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ARVO Annual Meeting Abstract July 2018

Human HSV-Specific Memory CD8 + T EM Cells with Unique JAK/STAT, Chemokine and Anti-Inflammatory Gene Signatures Are Associated with Asymptomatic Ocular Herpes Infection

Lbachir BenMohamed; Hawa Vahed; Ruchi Srivastava; Anthony B Nesburn

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):519. doi:

ARVO Annual Meeting Abstract July 2018

Blockade of Lymphocyte activation gene-3 (LAG-3) Pathway Improved the Size and Protective Function of Herpes Simplex Virus-Specific CD8 + T cells against Ocular Herpes Infection and Disease

Anthony B Nesburn; Ruchi Srivastava; Roy Soumyabrata; Lbachir BenMohamed

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):520. doi:

ARVO Annual Meeting Abstract July 2018

Effects of Anti-VEGF and ALG-1001 on Human Retinal Cells in vitro

Cristina M Kenney; Marilyn Chwa; Javier Cáceres-del-Carpio; Deepika Malik; Shari Atilano; Kevin Schneider; G. Astrid Limb; David S Boyer; Anthony B Nesburn; Baruch D Kuppermann

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):771. doi:

ARVO Annual Meeting Abstract July 2018

PU-91, a mitochondria-stabilizing drug, rescues AMD ARPE-19 cybrid cells; implications for macular degeneration therapeutics

Sonali Nashine; Marilyn Chwa; Shari Atilano; Sudhakar R. Subramaniam; Howard Federoff; Anthony B Nesburn; Baruch D Kuppermann; Cristina M Kenney

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3268. doi:

ARVO Annual Meeting Abstract June 2017

Age-related macular degeneration (AMD) mitochondria modulate epigenetic machinery in transmitochondrial ARPE-19 cybrid cells

Sonali R Nashine; Stephanie Yiwei Lu; Anthony B Nesburn; Baruch D Kuppermann; Cristina M Kenney

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):612. doi:

ARVO Annual Meeting Abstract June 2017

The CXCL10/CXCR3 Chemokine Pathway is Required for the Generation and Protective Function of Tissue-Resident Memory CD103 + CD8 + T RM Cells Against Recurrent Ocular Herpes

Lbachir BenMohamed; Anthony B. Nesburn; Ruchi Srivastava

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3621. doi:

ARVO Annual Meeting Abstract June 2017

Mitochondrial DNA sensing by STING pathway mediates complement, inflammation and epigenetic genes

Cristina M Kenney; Kevin Schneider; Shari R. Atilano; Marilyn Chwa; Sonali R Nashine; Stephanie Yiwei Lu; Anthony B Nesburn; Baruch D Kuppermann

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5251. doi:

ARVO Annual Meeting Abstract September 2016

The Herpes Simplex Virus LAT Gene is Associated with a Broader Repertoire of Virus-Specific Exhausted CD8 + T Cells Retained within the Trigeminal Ganglia of Latently Infected HLA Transgenic Rabbits

Lbachir BenMohamed; Arif Khan; Ruchi Srivastava; Steven Wechsler; Anthony B Nesburn

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3293. doi:

ARVO Annual Meeting Abstract September 2016

Increased Frequency of Herpes Simplex Virus-Specific Effector Memory CD26+CD8+ T Cells in HSV-Seropositive Ocular Herpes Asymptomatic Patients

Anthony B Nesburn; Ruchi Srivastava; Arif Khan; Steven Wechsler; Lbachir BenMohamed

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3318. doi:

ARVO Annual Meeting Abstract September 2016

Mitochondria from AMD subjects can mediate RNA and protein levels of complement markers in transmitochondrial cybrids

Cristina M Kenney; Sonali R Nashine; Shari R Atilano; Marilyn Chwa; Mina Kazemian; Kunal Thaker; Stephanie Lu; Anthony B Nesburn; Baruch D Kuppermann

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5803. doi:

ARVO Annual Meeting Abstract September 2016

Comparison of Lipid and Cholesterol-Biosynthesis Gene Products in H- and K-mt-DNA haplogroup cybrids

Christine Garabetian; Kunal Thaker; Javier Cáceres-del-Carpio; Shari R Atilano; Marilyn Chwa; Anthony B Nesburn; Cristina M Kenney

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6054. doi:

Immunology and Microbiology June 2015

A Herpes Simplex Virus Type 1 Human Asymptomatic CD8 + T-Cell Epitopes-Based Vaccine Protects Against Ocular Herpes in a “Humanized” HLA Transgenic Rabbit Model

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Ruchi Srivastava; Arif A. Khan; Jiawei Huang; Anthony B. Nesburn; Steven L. Wechsler; Lbachir BenMohamed
TAGS: animals, transgenic, human leukocyte antigens, epitopes, epitopes, t-lymphocyte, gabon, human herpesvirus 1, hla-a2 antigen, immunization, keratitis, herpetic, peptides, oryctolagus cuniculus, t-lymphocyte, vaccines, united kingdom
Invest. Ophthalmol. Vis. Sci.. 2015; 56(6):4013-4028. doi: 10.1167/iovs.15-17074

ARVO Annual Meeting Abstract June 2015

Phenotypic and Functional Characterization of Herpes Simplex Virus Glycoprotein B Epitope-specific Effector and Memory CD8 + T Cells from Ocular Herpes Symptomatic and Asymptomatic Individuals

Lbachir BenMohamed; Arif A Khan; Ruchi Srivastava; Doran Spencer; Sumit Garg; Steven Wechsler; Anthony B Nesburn

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4402. doi:

ARVO Annual Meeting Abstract June 2015

HLA-A02:01-Restricted Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP11/12 Preferentially Recall Polyfunctional Effector Memory CD8 + T Cells from Seropositive Asymptomatic Individuals and Protect “Humanized” HLA-A*02:01 Transgenic Mice Against Ocular Herpes

Ruchi Srivastava; Arif A Khan; Doran Spencer; Sumit Garg; Anthony B Nesburn; Steven Wechsler; Lbachir BenMohamed

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1858. doi:

ARVO Annual Meeting Abstract April 2014

Identification of Herpes Simplex Virus Glycoprotein B Human Epitopes That Preferentially Recall Polyfunctional CD8+ T Cells from Seropositive Asymptomatic Individuals and Protect HLA Transgenic Mice Against Ocular Herpes

Anthony B Nesburn; Arif Khan; Ruchi Srivastava; Steven L Wechsler1; Lbachir BenMohamed

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):6255. doi:

ARVO Annual Meeting Abstract April 2014

Different Epigenetic Methylation Patterns in Cells with African versus European Inherited Mitochondrial DNA Haplogroups: Possible Mechanism for Disease Susceptibilities?

Cristina M Kenney; Deepika Malik; Shari Atilano; Javier Caceres del Carpio; Marilyn Chwa; Anthony B Nesburn; David S Boyer; Baruch Kuppermann; Nitin Udar

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2189. doi:

ARVO Annual Meeting Abstract April 2014

Differential Role of HSV-Specific Central vs. Effector Memory CD8+ T Cells in Ocular Herpes Disease

Lbachir BenMohamed; Arif Khan; Ruchi Srivastava; Thanh T Pham; Patricia P Lopes; Bertrand Wechsler; Anthony B Nesburn

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4061. doi:

ARVO Annual Meeting Abstract March 2012

The Herpes Simplex Virus Type 1 Latency Associated Transcript Inhibits Phenotypic and Functional Maturation of Dendritic Cells

Lbachir BenMohamed; Aziz A. Chentoufi; Xavier Dervillez; Gargi Dasgupta; Chelsea Nguyen; Khaled K. Kabbara; Steven L. Wechsler; Anthony B. Nesburn

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6147. doi:

ARVO Annual Meeting Abstract March 2012

Protective Asymptomatic Human Leukocyte Antigen (HLA)-A*0201-Restricted CD8+ Cytotoxic T-Lymphocyte Epitopes Identified from Herpes Simplex Virus Glycoprotein B

Anthony B. Nesburn; Xavier Dervillez; Aziz A. Chentoufi; Gargi Dasgupta; Khaled W. Kabbara; Maria C. Villacres; Chelsea Nguyen; Steven L. Wechsler; Lbachir BenMohamed

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6152. doi:

ARVO Annual Meeting Abstract March 2012

Accumulation of Reactive Oxygen/Nitrogen Species is a Result of Decreased Expression of Antioxidant Enzymes in Keratoconus Cells

Payam Falatoonzadeh; Shari R. Atilano; Marilyn Chwa; Janelle Pavlis; Anthony B. Nesburn; Nitin Udar; Maria C. Kenney

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1108. doi:

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Human HSV-Specific Memory CD8 + T EM Cells with Unique JAK/STAT, Chemokine and Anti-Inflammatory Gene Signatures Are Associated with Asymptomatic Ocular Herpes Infection

Blockade of Lymphocyte activation gene-3 (LAG-3) Pathway Improved the Size and Protective Function of Herpes Simplex Virus-Specific CD8 + T cells against Ocular Herpes Infection and Disease

Effects of Anti-VEGF and ALG-1001 on Human Retinal Cells in vitro

PU-91, a mitochondria-stabilizing drug, rescues AMD ARPE-19 cybrid cells; implications for macular degeneration therapeutics

Age-related macular degeneration (AMD) mitochondria modulate epigenetic machinery in transmitochondrial ARPE-19 cybrid cells

The CXCL10/CXCR3 Chemokine Pathway is Required for the Generation and Protective Function of Tissue-Resident Memory CD103 + CD8 + T RM Cells Against Recurrent Ocular Herpes

Mitochondrial DNA sensing by STING pathway mediates complement, inflammation and epigenetic genes

The Herpes Simplex Virus LAT Gene is Associated with a Broader Repertoire of Virus-Specific Exhausted CD8 + T Cells Retained within the Trigeminal Ganglia of Latently Infected HLA Transgenic Rabbits

Increased Frequency of Herpes Simplex Virus-Specific Effector Memory CD26+CD8+ T Cells in HSV-Seropositive Ocular Herpes Asymptomatic Patients

Mitochondria from AMD subjects can mediate RNA and protein levels of complement markers in transmitochondrial cybrids

Comparison of Lipid and Cholesterol-Biosynthesis Gene Products in H- and K-mt-DNA haplogroup cybrids

A Herpes Simplex Virus Type 1 Human Asymptomatic CD8 + T-Cell Epitopes-Based Vaccine Protects Against Ocular Herpes in a “Humanized” HLA Transgenic Rabbit Model

Phenotypic and Functional Characterization of Herpes Simplex Virus Glycoprotein B Epitope-specific Effector and Memory CD8 + T Cells from Ocular Herpes Symptomatic and Asymptomatic Individuals

HLA-A02:01-Restricted Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP11/12 Preferentially Recall Polyfunctional Effector Memory CD8 + T Cells from Seropositive Asymptomatic Individuals and Protect “Humanized” HLA-A*02:01 Transgenic Mice Against Ocular Herpes

Identification of Herpes Simplex Virus Glycoprotein B Human Epitopes That Preferentially Recall Polyfunctional CD8+ T Cells from Seropositive Asymptomatic Individuals and Protect HLA Transgenic Mice Against Ocular Herpes

Different Epigenetic Methylation Patterns in Cells with African versus European Inherited Mitochondrial DNA Haplogroups: Possible Mechanism for Disease Susceptibilities?

Differential Role of HSV-Specific Central vs. Effector Memory CD8+ T Cells in Ocular Herpes Disease

The Herpes Simplex Virus Type 1 Latency Associated Transcript Inhibits Phenotypic and Functional Maturation of Dendritic Cells

Protective Asymptomatic Human Leukocyte Antigen (HLA)-A*0201-Restricted CD8+ Cytotoxic T-Lymphocyte Epitopes Identified from Herpes Simplex Virus Glycoprotein B

Accumulation of Reactive Oxygen/Nitrogen Species is a Result of Decreased Expression of Antioxidant Enzymes in Keratoconus Cells

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