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ARVO Annual Meeting Abstract June 2021

Efficacy, durability, and safety of faricimab in diabetic macular edema (DME): one-year results from the phase 3 YOSEMITE and RHINE trials

John A Wells; Charles Clifton Wykoff; Jeffrey R Willis; Zdenka Haskova; Hugh Lin; David Silverman; Anthony P Adamis; Jane Ives; Francis Abreu; Karen Basu; Ramin Tadayoni

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1037. doi:

ARVO Annual Meeting Abstract July 2019

Deep learning predicts OCT measures of diabetic macular thickening from color fundus photographs

Jeffrey Ryuta Willis; Filippo Arcadu; Fethallah Benmansour; Andreas Maunz; John Michon; Zdenka Haskova; Dana McClintock; Anthony P Adamis; Marco Prunotto

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1538. doi:

Retina March 2019

Deep Learning Predicts OCT Measures of Diabetic Macular Thickening From Color Fundus Photographs

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Filippo Arcadu; Fethallah Benmansour; Andreas Maunz; John Michon; Zdenka Haskova; Dana McClintock; Anthony P. Adamis; Jeffrey R. Willis; Marco Prunotto
TAGS: color, deep learning, diabetes mellitus, diabetic macular edema, fundus photography, datasets
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):852-857. doi: https://doi.org/10.1167/iovs.18-25634

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Cardiovascular and cerebrovascular safety of ranibizumab (RBZ) in diabetic macular edema (DME): A comprehensive patient-level meta-analysis at month 12

Howard Snow; Natasha Singh; Soumil Parikh; Steven Francom; Cornelia Dunger-Baldauf; Zdenka Haskova; Philippe Margaron; Anthony P Adamis

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1506. doi:

Translational Research June 2014

Spontaneous CNV in a Novel Mutant Mouse Is Associated With Early VEGF-A–Driven Angiogenesis and Late-Stage Focal Edema, Neural Cell Loss, and Dysfunction

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Norihiro Nagai; Pete Lundh von Leithner; Kanako Izumi-Nagai; Brett Hosking; Bo Chang; Ron Hurd; Peter Adamson; Anthony P. Adamis; Richard H. Foxton; Yin Shan Ng; David T. Shima
TAGS: choroidal neovascularization, edema, mice, pathophysiology, vascular endothelial growth factor a, angiogenesis, neurons
Invest. Ophthalmol. Vis. Sci.. 2014; 55(6):3709-3719. doi: https://doi.org/10.1167/iovs.14-13989

Includes: Multimedia, Supplemental Content

Lecture April 2011

Introducing Jayakrishna Ambati, the Recipient of the 2010 Cogan Award

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Anthony P. Adamis
TAGS: awards and prizes
Invest. Ophthalmol. Vis. Sci.. 2011; 52(5):2165. doi: https://doi.org/10.1167/iovs.11-7329

Physiology and Pharmacology February 2010

Assessment of the Integrin α5β1 Antagonist JSM6427 in Proliferative Vitreoretinopathy Using In Vitro Assays and a Rabbit Model of Retinal Detachment

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Grit Zahn; Kristine Volk; Geoffrey P. Lewis; Dörte Vossmeyer; Roland Stragies; Jeffrey S. Heier; Paul E. Daniel, Jr; Anthony P. Adamis; Ethan A. Chapin; Steven K. Fisher; Frank G. Holz; Karin U. Löffler; Jochen Knolle
TAGS: integrins, oryctolagus cuniculus, retinal detachment, vitreoretinopathy, proliferative, antagonists, tissue membrane
Invest. Ophthalmol. Vis. Sci.. 2010; 51(2):1028-1035. doi: https://doi.org/10.1167/iovs.09-3575

Physiology and Pharmacology February 2008

Simultaneous but Not Prior Inhibition of VEGF165 Enhances the Efficacy of Photodynamic Therapy in Multiple Models of Ocular Neovascularization

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Meihua Ju; Carolina Mailhos; John Bradley; Tracy Dowie; Mary Ganley; Gary Cook; Perry Calias; Norbert Lange; Anthony P. Adamis; David T. Shima; Gregory S. Robinson
TAGS: cornea, neovascularization, pathologic, pegaptanib, photochemotherapy, sodium, choroidal neovascularization
Invest. Ophthalmol. Vis. Sci.. 2008; 49(2):662-670. doi: https://doi.org/10.1167/iovs.07-0195

Includes: Supplemental Content

Glaucoma March 2007

Erythropoietin Promotes Survival of Retinal Ganglion Cells in DBA/2J Glaucoma Mice

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Lichun Zhong; John Bradley; William Schubert; Ednan Ahmed; Anthony P. Adamis; David T. Shima; Gregory S. Robinson; Yin-Shan Ng
TAGS: erythropoietin, glaucoma, mice, retinal ganglion cells, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2007; 48(3):1212-1218. doi: https://doi.org/10.1167/iovs.06-0757

Includes: Supplemental Content

Retina February 2007

Inhibition of Diabetic Leukostasis and Blood-Retinal Barrier Breakdown with a Soluble Form of a Receptor for Advanced Glycation End Products

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Yuichi Kaji; Tomohiko Usui; Susumu Ishida; Kenji Yamashiro; Tara C. B. Moore; Jonathan Moore; Yasuhiko Yamamoto; Hiroshi Yamamoto; Anthony P. Adamis
TAGS: blood-retinal barrier, diabetes mellitus, leukostasis, rage, receptor for advanced glycation endproducts, intercellular adhesion molecule 1, vascular endothelial growth factor a, mice
Invest. Ophthalmol. Vis. Sci.. 2007; 48(2):858-865. doi: https://doi.org/10.1167/iovs.06-0495

Biochemistry and Molecular Biology February 2004

VEGF 164(165) as the Pathological Isoform: Differential Leukocyte and Endothelial Responses through VEGFR1 and VEGFR2

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Tomohiko Usui; Susumu Ishida; Kenji Yamashiro; Yuichi Kaji; Vasiliki Poulaki; Johnny Moore; Tara Moore; Shiro Amano; Yoshitaka Horikawa; Darlene Dartt; Matthew Golding; David T. Shima; Anthony P. Adamis
TAGS: protein isoforms, vascular endothelial growth factor a, leukocytes
Invest. Ophthalmol. Vis. Sci.. 2004; 45(2):368-374. doi: https://doi.org/10.1167/iovs.03-0106

Retina October 2003

The Role of Advanced Glycation End Products in Retinal Microvascular Leukostasis

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Tara C. B. Moore; Jonathan E. Moore; Yuichi Kaji; Norma Frizzell; Tomohiko Usui; Vasiliki Poulaki; Iain L. Campbell; Alan W. Stitt; Tom A. Gardiner; Desmond B. Archer; Anthony P. Adamis
TAGS: glycosylation end products, advanced, intercellular adhesion molecule 1, leukostasis, mice, proteins, endothelial cells, albumins, blood-retinal barrier, retina, rna, messenger
Invest. Ophthalmol. Vis. Sci.. 2003; 44(10):4457-4464. doi: https://doi.org/10.1167/iovs.02-1063

Retina June 2003

Targeted Disruption of the CD18 or ICAM-1 Gene Inhibits Choroidal Neovascularization

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Eiji Sakurai; Hogara Taguchi; Akshay Anand; Balamurali K. Ambati; Evangelos S. Gragoudas; Joan W. Miller; Anthony P. Adamis; Jayakrishna Ambati
TAGS: cd18 antigens, choroidal neovascularization, intercellular adhesion molecule 1, genes
Invest. Ophthalmol. Vis. Sci.. 2003; 44(6):2743-2749. doi: https://doi.org/10.1167/iovs.02-1246

Retina May 2003

VEGF 164 Is Proinflammatory in the Diabetic Retina

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Susumu Ishida; Tomohiko Usui; Kenji Yamashiro; Yuichi Kaji; Ednan Ahmed; Karen G. Carrasquillo; Shiro Amano; Tetsuo Hida; Yoshihisa Oguchi; Anthony P. Adamis
TAGS: diabetes mellitus, leukostasis, retina, vascular endothelial growth factor a, intercellular adhesion molecule 1
Invest. Ophthalmol. Vis. Sci.. 2003; 44(5):2155-2162. doi: https://doi.org/10.1167/iovs.02-0807

Cornea February 2003

Expression and Function of Receptors for Advanced Glycation End Products in Bovine Corneal Endothelial Cells

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Yuichi Kaji; Shiro Amano; Tomohiko Usui; Tetsuro Oshika; Kenji Yamashiro; Susumu Ishida; Kaori Suzuki; Sumiyoshi Tanaka; Anthony P. Adamis; Ryoji Nagai; Seiko Horiuchi
TAGS: cattle, chronic exertional compartment syndrome, cornea, endothelial cells, galectin 3, glycosylation end products, advanced, rage, proteins, culture media
Invest. Ophthalmol. Vis. Sci.. 2003; 44(2):521-528. doi: https://doi.org/10.1167/iovs.02-0268

Cornea February 2003

Sustained Inhibition of Corneal Neovascularization by Genetic Ablation of CCR5

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Balamurali K. Ambati; Akshay Anand; Antonia M. Joussen; William A. Kuziel; Anthony P. Adamis; Jayakrishna Ambati
TAGS: ablation, chemokine (c-c motif) receptor 5, corneal neovascularization, genetics, vascular endothelial growth factor a, cornea
Invest. Ophthalmol. Vis. Sci.. 2003; 44(2):590-593. doi: https://doi.org/10.1167/iovs.02-0685

Physiology and Pharmacology January 2003

Controlled Delivery of the Anti-VEGF Aptamer EYE001 with Poly(lactic- co -glycolic)Acid Microspheres

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Karen G. Carrasquillo; Joseph A. Ricker; Ioannis K. Rigas; Joan W. Miller; Evangelos S. Gragoudas; Anthony P. Adamis
TAGS: anti-vascular endothelial growth factor therapy, microspheres
Invest. Ophthalmol. Vis. Sci.. 2003; 44(1):290-299. doi: https://doi.org/10.1167/iovs.01-1156

Cornea January 2003

VEGF-Dependent Conjunctivalization of the Corneal Surface

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Antonia M. Joussen; Vassiliki Poulaki; Nicholas Mitsiades; Stephen U. Stechschulte; Bernd Kirchhof; Darlene A. Dartt; Guo-Hua Fong; John Rudge; Stanley J. Wiegand; George D. Yancopoulos; Anthony P. Adamis
TAGS: cornea, corneal neovascularization, goblet cells, vascular endothelial growth factor a, vegfr-1, epithelium
Invest. Ophthalmol. Vis. Sci.. 2003; 44(1):117-123. doi: https://doi.org/10.1167/iovs.01-1277

Cornea September 2002

The Inflammatory Milieu Associated with Conjunctivalized Cornea and Its Alteration with IL-1 RA Gene Therapy

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Jonathan E. Moore; Tara C. B. McMullen; Iain L. Campbell; Richard Rohan; Yuichi Kaji; Natalie A. Afshari; Tomo Usui; Desmond B. Archer; Anthony P. Adamis
TAGS: cornea, interleukin-1, transfection, wounds and injuries, cytokine
Invest. Ophthalmol. Vis. Sci.. 2002; 43(9):2905-2915. doi:

Physiology and Pharmacology April 2002

Role of Syndecan-1 in Leukocyte–Endothelial Interactions in the Ocular Vasculature

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Martin Götte; Antonia M. Joussen; Christoph Klein; Patrick Andre; Denisa D. Wagner; Michael T. Hinkes; Bernd Kirchhof; Anthony P. Adamis; Merton Bernfield
TAGS: cd138, endothelium, leukocytes, mice, vasculature, leukocyte cell adhesion, corneal neovascularization
Invest. Ophthalmol. Vis. Sci.. 2002; 43(4):1135-1141. doi:

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Efficacy, durability, and safety of faricimab in diabetic macular edema (DME): one-year results from the phase 3 YOSEMITE and RHINE trials

Deep learning predicts OCT measures of diabetic macular thickening from color fundus photographs

Deep Learning Predicts OCT Measures of Diabetic Macular Thickening From Color Fundus Photographs

Cardiovascular and cerebrovascular safety of ranibizumab (RBZ) in diabetic macular edema (DME): A comprehensive patient-level meta-analysis at month 12

Spontaneous CNV in a Novel Mutant Mouse Is Associated With Early VEGF-A–Driven Angiogenesis and Late-Stage Focal Edema, Neural Cell Loss, and Dysfunction

Introducing Jayakrishna Ambati, the Recipient of the 2010 Cogan Award

Assessment of the Integrin α5β1 Antagonist JSM6427 in Proliferative Vitreoretinopathy Using In Vitro Assays and a Rabbit Model of Retinal Detachment

Simultaneous but Not Prior Inhibition of VEGF165 Enhances the Efficacy of Photodynamic Therapy in Multiple Models of Ocular Neovascularization

Erythropoietin Promotes Survival of Retinal Ganglion Cells in DBA/2J Glaucoma Mice

Inhibition of Diabetic Leukostasis and Blood-Retinal Barrier Breakdown with a Soluble Form of a Receptor for Advanced Glycation End Products

VEGF 164(165) as the Pathological Isoform: Differential Leukocyte and Endothelial Responses through VEGFR1 and VEGFR2

The Role of Advanced Glycation End Products in Retinal Microvascular Leukostasis

Targeted Disruption of the CD18 or ICAM-1 Gene Inhibits Choroidal Neovascularization

VEGF 164 Is Proinflammatory in the Diabetic Retina

Expression and Function of Receptors for Advanced Glycation End Products in Bovine Corneal Endothelial Cells

Sustained Inhibition of Corneal Neovascularization by Genetic Ablation of CCR5

Controlled Delivery of the Anti-VEGF Aptamer EYE001 with Poly(lactic- co -glycolic)Acid Microspheres

VEGF-Dependent Conjunctivalization of the Corneal Surface

The Inflammatory Milieu Associated with Conjunctivalized Cornea and Its Alteration with IL-1 RA Gene Therapy

Role of Syndecan-1 in Leukocyte–Endothelial Interactions in the Ocular Vasculature

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