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ARVO Annual Meeting Abstract June 2025

Uncovering potential texture-based approaches in retinal OCT imaging for the early diagnosis of diabetic retinopathy

Antonio Francisco Ambrosio; Sara Oliveira; Pedro Guimaraes; Angelo Rosado; Elisa Julião Campos; Pedro Serranho; Paulo Matafome; Rui Bernardes

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4223.

Multidisciplinary Ophthalmic Imaging January 2025

Retinal OCT-Derived Texture Features as Potential Biomarkers for Early Diagnosis and Progression of Diabetic Retinopathy

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Sara Oliveira; Pedro Guimarães; Elisa Julião Campos; Rosa Fernandes; João Martins; Miguel Castelo-Branco; Pedro Serranho; Paulo Matafome; Rui Bernardes; António Francisco Ambrósio
TAGS: biological markers, diabetes mellitus, diabetes mellitus, type 1, diabetic retinopathy, early diagnosis, retina, streptozocin, proteins
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):7. https://doi.org/10.1167/iovs.66.1.7

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Neuroprotective Impact of Müller Glia-Derived Microvesicles on Retinal Ganglion Cells Under High Pressure Conditions

Xandra Pereiro; Noelia Ruzafa; Carolina Santos; Mikel Azkargorta; Felix Elortza; António Francisco Ambrosio; Ana Raquel Santiago; Elena Vecino

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1677.

ARVO Annual Meeting Abstract June 2024

Texture of retinal OCT images as potential biomarker for early diagnosis of diabetic retinopathy: evidence from an animal model of type 1 diabetes

Sara Oliveira; Pedro Guimarães; Elisa Julião Campos; Rosa Fernandes; Pedro Serranho; Paulo Matafome; Rui Bernardes; António Francisco Ambrosio

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1370.

ARVO Annual Meeting Abstract June 2024

Ndr2 kinase regulates the microglia inflammatory response in high glucose conditions

Hélène M. Léger; Beatriz Fazendeiro; António Francisco Ambrosio; Paulo Fernando Martins dos Santos

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):934.

ARVO Annual Meeting Abstract June 2023

Sitagliptin, a drug for type 2 diabetes, significantly inhibits the pro-inflammatory microglia reactivity

António Francisco Ambrósio; Sandra Correia; Lucia Bufano; Cristiana Leote; Raquel Boia; Ana Raquel Santiago; Rosa Fernandes; Hélène Léger

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1006.

ARVO Annual Meeting Abstract June 2023

Different behavior of Müller cells according to their location in the retina: possible relation with the differential susceptibility of retinal ganglion cells in glaucoma.

Xandra Pereiro; Noelia Ruzafa; António Francisco Ambrósio; Ana Raquel Santiago; Elena Vecino

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1584.

ARVO Annual Meeting Abstract June 2023

EYS -ASSOCIATED RETINAL DEGENERATION: NATURAL HISTORY, GENETIC LANDSCAPE AND PHENOTYPIC SPECTRUM

Ricardo Soares; Ana Luísa Carvalho; Sílvia Simão; Célia Azevedo Soares; Miguel Raimundo; Henrique Alves; António Francisco Ambrósio; Joaquim Murta; Jorge Saraiva; Rufino Silva; João Pedro Marques

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4663.

ARVO Annual Meeting Abstract June 2021

Retinal microglial activation in the triple-transgenic Alzheimer’s Disease mouse model (3xTg-AD).

Juan J. Salazar; Elena Salobrar-García; Ana C. Rodrigues-Neves; Ana Ramirez; Rosa de Hoz; Jose A. Fernández-Albarral; Inés López Cuenca; Antonio F. Ambrosio; Jose Ramirez

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3103.

ARVO Annual Meeting Abstract July 2019

Adenosine A3 receptor agonist prevents the loss of retinal ganglion cells in a glaucoma model

Raquel Boia; Manuel Salinas-Navarro; Alejandro Gallego-Ortega; Caridad Galindo-Romero; Marta Agudo-Barriuso; Antonio F Ambrosio; Manuel Vidal-Sanz; Ana Raquel Santiago

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):625.

ARVO Annual Meeting Abstract July 2019

Extracellular vesicles released by microglia exposed to elevated hydrostatic pressure promote retinal neural cell loss and microglia reactivity

Ana Raquel Santiago; Ines Dinis Aires; Teresa Ribeiro-Rodrigues; Raquel Boia; Steve Catarino; Daniela Almeida; Henrique Girao; Antonio F Ambrosio

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4397.

ARVO Annual Meeting Abstract July 2019

Retinal thinning of inner layers is associated with visual cortex atrophy in a mouse model of Alzheimer’s disease: a longitudinal in vivo multimodal study

Antonio F Ambrosio; Samuel Chiquita; João Castelhano; Mário Ribeiro; José Sereno; Elisa J Campos; Paula I Moreira; Miguel Castelo-Branco

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4787.

ARVO Annual Meeting Abstract July 2019

Dipeptidyl deptidase-IV inhibition by sitagliptin slows down retinal neurodegeneration in rd10 mice retinas.

Oksana Kutsyr; Blanca Arango-Gonzalez; Laura Fernandez-Sanchez; Victoria Maneu; Pedro Lax; Antonio F Ambrosio; Marius Ueffing; Nicolas Cuenca

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4879.

ARVO Annual Meeting Abstract July 2018

Structural, functional and molecular alterations in the retina of a mouse model of Alzheimer’s disease

Antonio F Ambrosio; Catarina Neves; Samuel Chiquita; Rafael Carecho; Filipa Baptista; Elisa J. Campos; Paula Moreira

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6077.

ARVO Annual Meeting Abstract June 2017

Can the retina be used as a reliable mirror to evaluate changes occurring in the Alzheimer’s brain?

António Francisco Ambrósio; Samuel Chiquita; Catarina Neves; Rafael Carecho; Filipa Baptista; Elisa Campos; Paula Moreira

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5862.

Physiology and Pharmacology May 2016

Protective Effect of a GLP-1 Analog on Ischemia-Reperfusion Induced Blood–Retinal Barrier Breakdown and Inflammation

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Andreia Gonçalves; Cheng-Mao Lin; Arivalagan Muthusamy; Carlos Fontes-Ribeiro; António F. Ambrósio; Steven F. Abcouwer; Rosa Fernandes; David A. Antonetti
TAGS: blood-retinal barrier, glucagon-like peptide 1, inflammation, ischemia, microglia, pathophysiology, permeability, physiologic reperfusion, reperfusion therapy, wounds and injuries
Invest. Ophthalmol. Vis. Sci.. 2016; 57(6):2584-2592. https://doi.org/10.1167/iovs.15-19006

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Sitagliptin inhibits neuroinflammatory processes in retinal microglia

António Francisco Ambrósio; Sandra Correia; João Martins; Dan Brudzewsky; Elisa Campos; Ana Raquel Santiago

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3492.

Physiology and Pharmacology April 2015

Sildenafil Acutely Decreases Visual Responses in ON and OFF Retinal Ganglion Cells

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João Martins; Bogdan Kolomiets; Romain Caplette; José-Alain Sahel; Miguel Castelo-Branco; António F. Ambrósio; Serge Picaud
TAGS: sildenafil, mass or substance concentration per volume, retinal ganglion cells
Invest. Ophthalmol. Vis. Sci.. 2015; 56(4):2639-2648. https://doi.org/10.1167/iovs.14-15964

Retinal Cell Biology January 2013

Neuropeptide Y Receptors Y 1 and Y 2 are Present in Neurons and Glial Cells in Rat Retinal Cells in Culture

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Ana Santos-Carvalho; Célia A. Aveleira; Filipe Elvas; António Francisco Ambrósio; Cláudia Cavadas
TAGS: neurons, neuropeptide y, neuropeptide y receptor, cell culture techniques, neuroglia, retina
Invest. Ophthalmol. Vis. Sci.. 2013; 54(1):429-443. https://doi.org/10.1167/iovs.12-10776

ARVO Annual Meeting Abstract March 2012

Neuropeptide Y Protects Retinal Neural Cells From Glutamate-induced Toxicity Through The Activation Of NPY Y5 Receptor

Ana Santos-Carvalho; Antonio F. Ambrósio; Cláudia Cavadas

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6538.

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Uncovering potential texture-based approaches in retinal OCT imaging for the early diagnosis of diabetic retinopathy

Retinal OCT-Derived Texture Features as Potential Biomarkers for Early Diagnosis and Progression of Diabetic Retinopathy

Neuroprotective Impact of Müller Glia-Derived Microvesicles on Retinal Ganglion Cells Under High Pressure Conditions

Texture of retinal OCT images as potential biomarker for early diagnosis of diabetic retinopathy: evidence from an animal model of type 1 diabetes

Ndr2 kinase regulates the microglia inflammatory response in high glucose conditions

Sitagliptin, a drug for type 2 diabetes, significantly inhibits the pro-inflammatory microglia reactivity

Different behavior of Müller cells according to their location in the retina: possible relation with the differential susceptibility of retinal ganglion cells in glaucoma.

EYS -ASSOCIATED RETINAL DEGENERATION: NATURAL HISTORY, GENETIC LANDSCAPE AND PHENOTYPIC SPECTRUM

Retinal microglial activation in the triple-transgenic Alzheimer’s Disease mouse model (3xTg-AD).

Adenosine A3 receptor agonist prevents the loss of retinal ganglion cells in a glaucoma model

Extracellular vesicles released by microglia exposed to elevated hydrostatic pressure promote retinal neural cell loss and microglia reactivity

Retinal thinning of inner layers is associated with visual cortex atrophy in a mouse model of Alzheimer’s disease: a longitudinal in vivo multimodal study

Dipeptidyl deptidase-IV inhibition by sitagliptin slows down retinal neurodegeneration in rd10 mice retinas.

Structural, functional and molecular alterations in the retina of a mouse model of Alzheimer’s disease

Can the retina be used as a reliable mirror to evaluate changes occurring in the Alzheimer’s brain?

Protective Effect of a GLP-1 Analog on Ischemia-Reperfusion Induced Blood–Retinal Barrier Breakdown and Inflammation

Sitagliptin inhibits neuroinflammatory processes in retinal microglia

Sildenafil Acutely Decreases Visual Responses in ON and OFF Retinal Ganglion Cells

Neuropeptide Y Receptors Y 1 and Y 2 are Present in Neurons and Glial Cells in Rat Retinal Cells in Culture

Neuropeptide Y Protects Retinal Neural Cells From Glutamate-induced Toxicity Through The Activation Of NPY Y5 Receptor

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