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ARVO Annual Meeting Abstract September 2016

The Herpes Simplex Virus LAT Gene is Associated with a Broader Repertoire of Virus-Specific Exhausted CD8 + T Cells Retained within the Trigeminal Ganglia of Latently Infected HLA Transgenic Rabbits

Lbachir BenMohamed; Arif Khan; Ruchi Srivastava; Steven Wechsler; Anthony B Nesburn

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3293. doi:

ARVO Annual Meeting Abstract September 2016

Increased Frequency of Herpes Simplex Virus-Specific Effector Memory CD26+CD8+ T Cells in HSV-Seropositive Ocular Herpes Asymptomatic Patients

Anthony B Nesburn; Ruchi Srivastava; Arif Khan; Steven Wechsler; Lbachir BenMohamed

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3318. doi:

ARVO Annual Meeting Abstract September 2016

Functional Dissection Shows FOXE3 Contributes to Peters Anomaly through the Transcriptional Regulation of an Autophagy Associated Co-Chaperone, DNAJB1

Shahid Yar Khan; Shivakumar Vasanth; Firoz Kabir; Arif O. Khan; Zhiwei Ma; Sheikh Riazuddin; Nader Pourmand; Norann A Zaghloul; J. Fielding Hejtmancik; S Amer Riazuddin

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

Immunology and Microbiology June 2015

A Herpes Simplex Virus Type 1 Human Asymptomatic CD8 + T-Cell Epitopes-Based Vaccine Protects Against Ocular Herpes in a “Humanized” HLA Transgenic Rabbit Model

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Ruchi Srivastava; Arif A. Khan; Jiawei Huang; Anthony B. Nesburn; Steven L. Wechsler; Lbachir BenMohamed
TAGS: epitopes, human herpesvirus 1, human leukocyte antigens, keratitis, herpetic, oryctolagus cuniculus, peptides, t-lymphocytes, vaccines, hla-a2 antigen, immunization
Invest. Ophthalmol. Vis. Sci.. 2015; 56(6):4013-4028. doi: https://doi.org/10.1167/iovs.15-17074

ARVO Annual Meeting Abstract June 2015

Phenotypic and Functional Characterization of Herpes Simplex Virus Glycoprotein B Epitope-specific Effector and Memory CD8 + T Cells from Ocular Herpes Symptomatic and Asymptomatic Individuals

Lbachir BenMohamed; Arif A Khan; Ruchi Srivastava; Doran Spencer; Sumit Garg; Steven Wechsler; Anthony B Nesburn

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4402. doi:

ARVO Annual Meeting Abstract June 2015

Therapeutic Immunization with Herpes Simplex Virus Type 1 Glycoprotein D Derived “Asymptomatic” Human CD8 + T-cell Epitopes Protects Against Recurrent Ocular Herpetic in Latently Infected HLA Transgenic Rabbits: Correlation with low Frequency of Exhausted PD-1 + TIM-3 + CD8 + T Cells

Anthony Nesburn; Arif A Khan; Ruchi Srivastava; Steven Wechsler; Lbachir BenMohamed

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1855. doi:

ARVO Annual Meeting Abstract June 2015

HLA-A02:01-Restricted Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP11/12 Preferentially Recall Polyfunctional Effector Memory CD8 + T Cells from Seropositive Asymptomatic Individuals and Protect “Humanized” HLA-A*02:01 Transgenic Mice Against Ocular Herpes

Ruchi Srivastava; Arif A Khan; Doran Spencer; Sumit Garg; Anthony B Nesburn; Steven Wechsler; Lbachir BenMohamed

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1858. doi:

ARVO Annual Meeting Abstract June 2015

A common ancestral mutation in CRYBB3 identified in multiple consanguineous pedigrees with congenital cataracts

Xiaodong Jiao; Firoz Kabir; Arif Khan; Qiwei Wang; David Li; Shaheen N khan; Tayyab Husnain; Sheikh Riazuddin; J. Fielding Hejtmancik; S Amer Riazuddin

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2527. doi:

ARVO Annual Meeting Abstract June 2015

Results of candidate gene analysis for Peters anomaly phenotypes on the Arabian Peninsula

Arif Khan; Saleh Al-Mesfer; S Amer Riazuddin

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2535. doi:

Genetics January 2015

Brittle Cornea Syndrome ZNF469 Mutation Carrier Phenotype and Segregation Analysis of Rare ZNF469 Variants in Familial Keratoconus

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Alice E. Davidson; Edmondo Borasio; Petra Liskova; Arif O. Khan; Hala Hassan; Michael E. Cheetham; Vincent Plagnol; Fowzan S. Alkuraya; Stephen J. Tuft; Alison J. Hardcastle
TAGS: ehlers-danlos syndrome 6b, keratoconus, mutation, corneal diseases, phenotype, segregation analysis, cohort studies
Invest. Ophthalmol. Vis. Sci.. 2015; 56(1):578-586. doi: https://doi.org/10.1167/iovs.14-15792

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2014

Ocular and extraocular features of Arabian children with Peters anomaly

Arif O Khan; Saleh Al-Mesfer; Shahira Al-Turkmani; S Amer Riazuddin

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4504. doi:

ARVO Annual Meeting Abstract April 2014

Identification of Herpes Simplex Virus Glycoprotein B Human Epitopes That Preferentially Recall Polyfunctional CD8+ T Cells from Seropositive Asymptomatic Individuals and Protect HLA Transgenic Mice Against Ocular Herpes

Anthony B Nesburn; Arif Khan; Ruchi Srivastava; Steven L Wechsler1; Lbachir BenMohamed

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):6255. doi:

ARVO Annual Meeting Abstract April 2014

Transcriptional characterization of the nonsense allele of FOXE3 responsible for Peters anomaly

Shahid Y Khan; Arif O Khan; Mei-Chong W Lee; Zhiwei Ma; Sheikh Riazuddin; Robert N Cole; Nader Pourmand; James F Hejtmancik; John Dunnegan Gottach; Amer S Riazuddin

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):6414. doi:

ARVO Annual Meeting Abstract April 2014

Differential Role of HSV-Specific Central vs. Effector Memory CD8+ T Cells in Ocular Herpes Disease

Lbachir BenMohamed; Arif Khan; Ruchi Srivastava; Thanh T Pham; Patricia P Lopes; Bertrand Wechsler; Anthony B Nesburn

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4061. doi:

ARVO Annual Meeting Abstract June 2013

Functional characterization of a homozygous nonsense FOXE3 mutation that causes Peters anomaly in a consanguineous family

Arif Khan; Shahid Khan; Zhiwei Ma; Saleh Al-Mesfer; Shahira Al Turkmani; Sheikh Riazuddin; Walter Stark; James Hejtmancik; John Gottsch; S. Amer Riazuddin

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1352. doi:

ARVO Annual Meeting Abstract June 2013

High-coverage next-generation sequencing (NGS) for retinal dystrophies and Usher syndrome: High diagnostic yield, CNV detection, novel disease mechanisms and therapy targets

Hanno Bolz; Christine Neuhaus; Markus Preising; Arif Khan; Martin Gliem; Peter Charbel Issa; Uwe Wolfrum; Andreas Gal; Birgit Lorenz; Tobias Eisenberger

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):3373. doi:

ARVO Annual Meeting Abstract June 2013

IOP measurement with I-CARE Rebound TONOMETER, PNEUMOTONOMETER and TONOPEN IN SEDATED CHILDREN with glaucoma and controls

Fatemah Al-Shamlan; Jonathan Song; Deepak Edward; Ibrahim Al Jadaan; Sami Al Shahwan; Jose Morales; Arif Khan; Saleh Al-Mesfer; Abdulaziz Awad; Shahira Al Turkmani

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):5624. doi:

ARVO Annual Meeting Abstract March 2012

Biometric and Molecular Correlations in Posterior Microphthalmos

Tariq M. Almudhaiyan; Sawsan R. Nowilaty; Arif O. Khan; Mohamed A. Aldahmesh; Khalid F. Tabbara; Fowzan S. Alkuraya

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1542. doi:

ARVO Annual Meeting Abstract March 2012

Patterns of Submacular Fibrosis in the Enhanced S-Cone/Goldmann-Favre Syndrome

Sawsan R. Nowilaty; Arif O. Khan; Abdullah Abubaker; Leen Abu Safieh; Fowzan S. Alkuraya

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):5204. doi:

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology November 2009

Synergistic Divergence: A Distinct Ocular Motility Dysinnervation Pattern

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Darren T. Oystreck; Arif O. Khan; Antonio Aguirre Vila-Coro; Olugbemisola Oworu; Nada Al-Tassan; Wai-Man Chan; Elizabeth C. Engle; Thomas M. Bosley
TAGS: eye, eye movement, medial rectus muscle, abduction, gaze
Invest. Ophthalmol. Vis. Sci.. 2009; 50(11):5213-5216. doi: https://doi.org/10.1167/iovs.08-2928

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The Herpes Simplex Virus LAT Gene is Associated with a Broader Repertoire of Virus-Specific Exhausted CD8 + T Cells Retained within the Trigeminal Ganglia of Latently Infected HLA Transgenic Rabbits

Increased Frequency of Herpes Simplex Virus-Specific Effector Memory CD26+CD8+ T Cells in HSV-Seropositive Ocular Herpes Asymptomatic Patients

Functional Dissection Shows FOXE3 Contributes to Peters Anomaly through the Transcriptional Regulation of an Autophagy Associated Co-Chaperone, DNAJB1

A Herpes Simplex Virus Type 1 Human Asymptomatic CD8 + T-Cell Epitopes-Based Vaccine Protects Against Ocular Herpes in a “Humanized” HLA Transgenic Rabbit Model

Phenotypic and Functional Characterization of Herpes Simplex Virus Glycoprotein B Epitope-specific Effector and Memory CD8 + T Cells from Ocular Herpes Symptomatic and Asymptomatic Individuals

Therapeutic Immunization with Herpes Simplex Virus Type 1 Glycoprotein D Derived “Asymptomatic” Human CD8 + T-cell Epitopes Protects Against Recurrent Ocular Herpetic in Latently Infected HLA Transgenic Rabbits: Correlation with low Frequency of Exhausted PD-1 + TIM-3 + CD8 + T Cells

HLA-A02:01-Restricted Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP11/12 Preferentially Recall Polyfunctional Effector Memory CD8 + T Cells from Seropositive Asymptomatic Individuals and Protect “Humanized” HLA-A*02:01 Transgenic Mice Against Ocular Herpes

A common ancestral mutation in CRYBB3 identified in multiple consanguineous pedigrees with congenital cataracts

Results of candidate gene analysis for Peters anomaly phenotypes on the Arabian Peninsula

Brittle Cornea Syndrome ZNF469 Mutation Carrier Phenotype and Segregation Analysis of Rare ZNF469 Variants in Familial Keratoconus

Ocular and extraocular features of Arabian children with Peters anomaly

Identification of Herpes Simplex Virus Glycoprotein B Human Epitopes That Preferentially Recall Polyfunctional CD8+ T Cells from Seropositive Asymptomatic Individuals and Protect HLA Transgenic Mice Against Ocular Herpes

Transcriptional characterization of the nonsense allele of FOXE3 responsible for Peters anomaly

Differential Role of HSV-Specific Central vs. Effector Memory CD8+ T Cells in Ocular Herpes Disease

Functional characterization of a homozygous nonsense FOXE3 mutation that causes Peters anomaly in a consanguineous family

High-coverage next-generation sequencing (NGS) for retinal dystrophies and Usher syndrome: High diagnostic yield, CNV detection, novel disease mechanisms and therapy targets

IOP measurement with I-CARE Rebound TONOMETER, PNEUMOTONOMETER and TONOPEN IN SEDATED CHILDREN with glaucoma and controls

Biometric and Molecular Correlations in Posterior Microphthalmos

Patterns of Submacular Fibrosis in the Enhanced S-Cone/Goldmann-Favre Syndrome

Synergistic Divergence: A Distinct Ocular Motility Dysinnervation Pattern

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