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Articles December 2019

Topical Brimonidine or Intravitreal BDNF, CNTF, or bFGF Protect Cones Against Phototoxicity

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Francisco J. Valiente-Soriano; Arturo Ortín-Martínez; Johnny Di Pierdomenico; Diego García-Ayuso; Alejandro Gallego-Ortega; Juan A. Miralles de Imperial-Ollero; Manuel Jiménez-López; María Paz Villegas-Pérez; Larry A. Wheeler; Manuel Vidal-Sanz
TAGS: brain-derived neurotrophic factor, brimonidine, ciliary neurotrophic factor, fibroblast growth factor 2, lip, phototoxicity, retina, retinal cone, opsin, mice
Trans. Vis. Sci. Tech.. 2019; 8(6):36. doi: https://doi.org/10.1167/tvst.8.6.36

ARVO Annual Meeting Abstract July 2019

Transplanted photoreceptors exchange proteins to host photoreceptors via neurites

Arturo Ortin-Martinez; En Leh Samuel Tsai; Lacrimioara Comanita; Nicole Yan; Nobuhiko Tachibana; Akshay Gurdita; Zhongda Chris Liu; Philip Nickerson; Suying Lu; Rod Bremner; Valerie Wallace

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):442. doi:

ARVO Annual Meeting Abstract July 2019

An in-vitro retina aggregate system to investigate the effects of environment on photoreceptor neurite outgrowth

En Leh Samuel Tsai; Arturo Ortin-Martinez; Akshay Gurdita; Lacrimioara Comanita; Nicole Yan; Sheila Smiley; Philip Nickerson; Vianney Delplace; Molly Shoichet; Valerie Wallace

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3312. doi:

ARVO Annual Meeting Abstract July 2019

Making eyes invisible to make things more visible: An optimized tissue clearing approach for three-dimensional imaging and high-throughput analysis of whole rodent eyes

Akshay Gurdita; Philip Nickerson; Neno Pokrajac; Arturo Ortin-Martinez; Samuel Tsai; Lacrimioara Comanita; Nobuhiko Tachibana; Zhongda Chris Liu; Danian Chen; Rod Bremner; Valerie Wallace

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5990. doi:

ARVO Annual Meeting Abstract July 2019

A novel in vitro model of intracellular protein exchange between primary photoreceptors

Nicole Yan; Lacrimioara Comanita; Zhongda Chris Liu; Arturo Ortin-Martinez; En Leh Samuel Tsai; Nobuhiko Tachibana; Valerie Wallace

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6040. doi:

ARVO Annual Meeting Abstract September 2016

Study of the neuroprotective effects of BDNF, bFGF, CNTF or several doses of PEDF in a focal Light-emission-diode (LED) - induced phototoxicity model in adult albino mice

F Javier Valiente-Soriano; Diego García-Ayuso; Arturo Ortin-Martinez; Manuel Jimenez-Lopez; Yolanda Caja-Matas; Antonio Cánovas-León; Jose Manuel Bernal-Garro; S Patricia Becerra; María Paz Villegas-Pérez; Manuel Vidal-Sanz

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):186. doi:

Retina July 2015

Transient Downregulation of Melanopsin Expression After Retrograde Tracing or Optic Nerve Injury in Adult Rats

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Francisco M. Nadal-Nicolás; Maria H. Madeira; Manuel Salinas-Navarro; Manuel Jiménez-López; Caridad Galindo-Romero; Arturo Ortín-Martínez; Ana Raquel Santiago; Manuel Vidal-Sanz; Marta Agudo-Barriuso
TAGS: axotomy, melanopsin, retina, rats, down-regulation, spinal cord injuries, albinism, optic nerve injuries
Invest. Ophthalmol. Vis. Sci.. 2015; 56(8):4309-4323. doi: https://doi.org/10.1167/iovs.15-16963

ARVO Annual Meeting Abstract June 2015

Focal Light-emitting-diode (LED)-induced cone photoreceptor degeneration in mice can be prevented with Brimonidine or trophic factors.

Manuel Vidal-Sanz; F Javier Valiente-Soriano; Arturo Ortin-Martinez; Diego García-Ayuso; Manuel Jiménez-López; Jose M Bernal-Garro; Luis Alarcón-Martínez; Larry A Wheeler; Maria Paz Villegas-Perez

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5667. doi:

ARVO Annual Meeting Abstract April 2014

DIFFERENCES IN CONE TYPE PROPORTIONS AND DISTRIBUTION BETWEEN PIGMENTED AND ALBINO STRAINS OF ADULT MICE

Manuel Vidal-Sanz; Arturo Ortin-Martinez; Francisco Manuel Nadal-Nicolas; Manuel Jimenez-Lopez; Juan J Alburquerque-Bejar; Leticia Nieto-Lopez; Maria Paz Villegas-Perez; Marta Agudo

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4366. doi:

ARVO Annual Meeting Abstract April 2014

Characterization of a new model of focal cone degeneration induced by a Light-emitting-diode (LED).

F Javier Valiente-Soriano; Arturo Ortin-Martinez; Diego García-Ayuso; Manuel Jimenez-Lopez; Luis Alarcon-Martinez; Jose Manuel Bernal-Garro; Francisco Manuel Nadal-Nicolas; Marta Agudo; Maria Paz Villegas-Perez; Manuel Vidal-Sanz

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4368. doi:

ARVO Annual Meeting Abstract April 2014

Cone neuroprotection afforded by Brimonidine and BDNF in a new model of focal Light-Emitting-Diode (LED)-induced phototoxicity

Arturo Ortin-Martinez; F Javier Valiente-Soriano; Diego García-Ayuso; Manuel Jimenez-Lopez; Luis Alarcon-Martinez; Jose Manuel Bernal-Garro; Leticia Nieto-Lopez; Marta Agudo; Maria Paz Villegas-Perez; Manuel Vidal-Sanz

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4369. doi:

Retina August 2013

Changes in the Photoreceptor Mosaic of P23H-1 Rats During Retinal Degeneration: Implications for Rod-Cone Dependent Survival

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Diego García-Ayuso; Arturo Ortín-Martínez; Manuel Jiménez-López; Caridad Galindo-Romero; Nicolás Cuenca; Isabel Pinilla; Manuel Vidal-Sanz; Marta Agudo-Barriuso; María P. Villegas-Pérez
TAGS: rats, retinal cone, rod photoreceptors, tissue degeneration, retinal degeneration, retina, photoreceptors, mosaicism
Invest. Ophthalmol. Vis. Sci.. 2013; 54(8):5888-5900. doi: https://doi.org/10.1167/iovs.13-12643

ARVO Annual Meeting Abstract March 2012

Whole Number And Spatial Distribution Of The Pou4f Family Of Transcription Factors In The Adult Rat Retina

Francisco M. Nadal-Nicolas; Manuel Jimemez-Lopez; Manuel Salinas-Navarro; Leticia Nieto-Lopez; Arturo Ortin-Martinez; Caridad Galindo-Romero; Maria Cielo Sanchez-Migallon; Paloma Sobrado-Calvo; Manuel Vidal-Sanz; Marta Agudo-Barriuso

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6562. doi:

ARVO Annual Meeting Abstract March 2012

IOP Induces Changes In The GFAP-Labelled Retinal Area But Not In Astrocyte Number In Mice Retina Contralateral To Experimental Glaucoma

Jose-Manuel Ramirez; Rosa De Hoz; Juan J. Salazar; Ana I. Ramirez; Blanca Rojas; Beatriz I. Gallego; Manuel Salinas-Navarro; Arturo Ortin-Martinez; Maria P. Villegas-Perez; Alberto Trivino

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):2025. doi:

ARVO Annual Meeting Abstract March 2012

Ocular Hypertension In The Adult Rat Retina Results In Protracted Loss Of S- And L-cones

Arturo Ortin-Martinez; Francisco M. Nadal-Nicolás; Manuel Salinas-Navarro; Francisco-Javier Valiente-Soriano; Juan-Jose Alburquerque-Bejar; Jose M. Bernal-Garro; Leticia Nieto-Lopez; Maria-Paz Villegas-Perez; Marta Agudo-Barriuso; Manuel Vidal-Sanz

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):2488. doi:

ARVO Annual Meeting Abstract April 2011

Cone Degeneration In A Model Of Hereditary Rod Degeneration: The P23H Rat

Diego Garcia-Ayuso; Arturo Ortín-Martínez; Marta Agudo-Barriuso; Manuel Jiménez-López; Jose Manuel Bernal-Garro; Leticia Nieto-López; Nicolas Cuenca; Isabel Pinilla; Manuel Vidal-Sanz; María Paz Villegas-Pérez

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):4338. doi:

ARVO Annual Meeting Abstract April 2011

Patterns Of Light-mediated C-fos Activity In The Medial Visual Cortex Of Mice Lacking Both Rods And Cones

F Javier Valiente-Soriano; Diego García-Ayuso; Arturo Ortín-Martínez; Ma'ayan Semo; Manuel Jiménez-López; Carlos Gias; Maria Paz Villegas-Pérez; Peter Coffey; Manuel Vidal-Sanz; Anthony A. Vugler

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3464. doi:

ARVO Annual Meeting Abstract April 2011

Population Of Melanopsin-expressing Retinal Ganglion Cells In Aging Wildtype And Rodless/coneless Mice: A Detailed Quantitative And Topographical Analysis

Arturo Ortin-Martinez; Diego García-Ayuso; F Javier Valiente-Soriano; Manuel Jímenez-López; María P. Villegas-Pérez; Marta Agudo-Barriuso; Pete Coffey; Anthony A. Vugler; Manuel Vidal-Sanz; Ma'ayam Semo

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3466. doi:

ARVO Annual Meeting Abstract April 2011

Shortly After Ocular Hypertension There Is Loss Of Retinal Ganglion Cells, But Not Of Other Cells Of The Ganglion Cell Layer Of The Retina

Manuel Salinas-Navarro; Francisco Manuel Nadal-Nicolás; Leticia López-Nieto; Manuel Jiménez-López; Arturo Ortín-Martínez; Diego García-Ayuso; Caridad Galindo-Romero; Marta Agudo-Barriuso; María Paz Villegas-Pérez; Manuel Vidal-Sanz

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2459. doi:

Glaucoma November 2010

Quantification of the Effect of Different Levels of IOP in the Astroglia of the Rat Retina Ipsilateral and Contralateral to Experimental Glaucoma

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Ana I. Ramírez; Juan J. Salazar; Rosa de Hoz; Blanca Rojas; Beatriz I. Gallego; Manuel Salinas-Navarro; Luis Alarcón-Martínez; Arturo Ortín-Martínez; Marcelino Avilés-Trigueros; Manuel Vidal-Sanz; Alberto Triviño; Jose M. Ramírez
TAGS: astrocytes, eye, glaucoma, intraocular pressure, retina, ocular hypertension, did not receive therapy or drug
Invest. Ophthalmol. Vis. Sci.. 2010; 51(11):5690-5696. doi: https://doi.org/10.1167/iovs.10-5248

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Topical Brimonidine or Intravitreal BDNF, CNTF, or bFGF Protect Cones Against Phototoxicity

Transplanted photoreceptors exchange proteins to host photoreceptors via neurites

An in-vitro retina aggregate system to investigate the effects of environment on photoreceptor neurite outgrowth

Making eyes invisible to make things more visible: An optimized tissue clearing approach for three-dimensional imaging and high-throughput analysis of whole rodent eyes

A novel in vitro model of intracellular protein exchange between primary photoreceptors

Study of the neuroprotective effects of BDNF, bFGF, CNTF or several doses of PEDF in a focal Light-emission-diode (LED) - induced phototoxicity model in adult albino mice

Transient Downregulation of Melanopsin Expression After Retrograde Tracing or Optic Nerve Injury in Adult Rats

Focal Light-emitting-diode (LED)-induced cone photoreceptor degeneration in mice can be prevented with Brimonidine or trophic factors.

DIFFERENCES IN CONE TYPE PROPORTIONS AND DISTRIBUTION BETWEEN PIGMENTED AND ALBINO STRAINS OF ADULT MICE

Characterization of a new model of focal cone degeneration induced by a Light-emitting-diode (LED).

Cone neuroprotection afforded by Brimonidine and BDNF in a new model of focal Light-Emitting-Diode (LED)-induced phototoxicity

Changes in the Photoreceptor Mosaic of P23H-1 Rats During Retinal Degeneration: Implications for Rod-Cone Dependent Survival

Whole Number And Spatial Distribution Of The Pou4f Family Of Transcription Factors In The Adult Rat Retina

IOP Induces Changes In The GFAP-Labelled Retinal Area But Not In Astrocyte Number In Mice Retina Contralateral To Experimental Glaucoma

Ocular Hypertension In The Adult Rat Retina Results In Protracted Loss Of S- And L-cones

Cone Degeneration In A Model Of Hereditary Rod Degeneration: The P23H Rat

Patterns Of Light-mediated C-fos Activity In The Medial Visual Cortex Of Mice Lacking Both Rods And Cones

Population Of Melanopsin-expressing Retinal Ganglion Cells In Aging Wildtype And Rodless/coneless Mice: A Detailed Quantitative And Topographical Analysis

Shortly After Ocular Hypertension There Is Loss Of Retinal Ganglion Cells, But Not Of Other Cells Of The Ganglion Cell Layer Of The Retina

Quantification of the Effect of Different Levels of IOP in the Astroglia of the Rat Retina Ipsilateral and Contralateral to Experimental Glaucoma

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