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ARVO Annual Meeting Abstract June 2025

Brain-derived neurotrophic factor deficiency triggers early loss of retinal ganglion cells in mice

Sabrina Reinehr; Julia Zehge; Katharina Klöster; Maike Müller; Hasan Hüseyin Hendek; H. Burkhard Dick; Ralf Gold; Simon Faissner; Stephanie C Joachim

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5340.

ARVO Annual Meeting Abstract June 2025

Optimized technique of the LIRIC (Laser-Induced-Refractive-Index-Change)-procedure for non-invasive, non-surgical correction of ametropia

Pascal Naubereit; Athina Chalkidis; Simas Sobutas; Agne Šuminiene; Stephanie C. Joachim; Teresa Tsai; H. Burkhard Dick; Samuel Arba Mosquera

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):170.

ARVO Annual Meeting Abstract June 2025

Intermittent fasting reduces glaucomatous damage in an HSP27 autoimmune mouse model

Dominik Leonard Maler; Sabrina Reinehr; Leonie Deppe; H. Burkhard Dick; Stephanie C Joachim

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4904.

ARVO Annual Meeting Abstract June 2025

Evaluating Oxidative Stress and Inflammatory Response in Porcine Corneas Following Laser-Induced Refractive Index Change (LIRIC)

Stephanie C Joachim; Rainer Koetter; Pascal Naubereit; Athina Chalkidis; H. Burkhard Dick; Teresa Tsai

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2298.

ARVO Annual Meeting Abstract June 2025

Divergent Pathways in Optic Neuritis: Transcriptomic Insights into Demyelinating Disorder Models

Maria Fernanda Valdes Michel; Sabrina Reinehr; Katharina Klöster; Erin N Capper; Jeffrey J Anders; Michael Chimenti; Laura Neumann; Randy H Kardon; H. Burkhard Dick; Ralf Gold; Simon Faissner; Stephanie C Joachim; Oliver W Gramlich

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3212.

ARVO Annual Meeting Abstract June 2024

The NLRP3 inflammasome mediates neurodegeneration in an ischemia-reperfusion injury model of acute angle-closure glaucoma

Andrew R. Griswold; Sarah B. Dickman; Victoria McGilligan; Meredith S Gregory-Ksander

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):699.

ARVO Annual Meeting Abstract June 2024

Early autophagy activation after retinal ischemia in mice

Teresa Tsai; Alexandra Strubbe; Leonie Deppe; H. Burkhard Dick; Stephanie C Joachim

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1256.

ARVO Annual Meeting Abstract June 2024

Phaco Longitudinal Mode Heat Generation, a Two-System Efficiency Comparison Study

Benjamin Dickerhoff; Asael Papour

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2090.

ARVO Annual Meeting Abstract June 2024

Induced oxidative stress in ex vivo porcine corneas downregulates mRNA expression

Stephanie C Joachim; Gülsüm Deniz Köseoğlu; Teresa Tsai; Pascal Naubereit; H. Burkhard Dick

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4504.

ARVO Annual Meeting Abstract June 2024

Advanced age accelerates inflammation in mice with high-pressure glaucoma

Sabrina Reinehr; Rahim Pamuk; Nils Kluge; Rudolf Fuchshofer; H. Burkhard Dick; Stephanie C Joachim

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6764.

Biochemistry and Molecular Biology October 2023

Investigation of Inter- and Intra-Day Variability of Tear Fluid Regarding Flow Rate, Protein Concentration as well as Protein Composition

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Annika Guntermann; Oluwaseun Fatoba; Marc Kronenberg; Sabrina Reinehr; Pia Grotegut; Marc Schargus; Teresa Tsai; Svetlana Ivanova; Bettina Serschnitzki; Nina Kumowski; Christoph Maier; Katrin Marcus; H. Burkhard Dick; Stephanie C. Joachim; Caroline May
TAGS: mass or substance concentration per volume, proteins, unit of flow rate
Invest. Ophthalmol. Vis. Sci.. 2023; 64(13):13. https://doi.org/10.1167/iovs.64.13.13

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

HPS27 induced glaucomatous damage in young and aged mice

Stephanie C Joachim; Clivia Erb; Carsten Theiss; Nina Schonhoven; H B Dick; Sabrina Reinehr

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1020.

ARVO Annual Meeting Abstract June 2023

Protection against oxidative stress by coenzyme Q10 in a porcine organculture

Teresa Tsai; Leonie Deppe; Ana M. Mueller-Buehl; H B Dick; Stephanie C Joachim

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2588.

ARVO Annual Meeting Abstract June 2023

Novel multifactorial glaucoma mouse model exhibits retinal T-cell response

Sabrina Reinehr; Julien Wulf; Kim Karla Schulte; Janine Theile; Marcus Peters; Rudolf Fuchshofer; H B Dick; Stephanie C Joachim

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3903.

ARVO Annual Meeting Abstract June 2023

Preclinical Pharmacokinetics and Bioavailability of VRDN-002, a Next-Generation Half-Life Extended Antagonist Antibody to IGF-1 Receptor for Thyroid Eye Disease (TED)

Robert Henderson; Kelly Foster; Brent Dickinson; Vahe Bedian

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4039.

ARVO Annual Meeting Abstract June 2023

VRDN-002, a Next-Generation Half-life Extended Antagonist Antibody to IGF-1 Receptor for Thyroid Eye Disease (TED): Safety and Pharmacokinetic/Pharmacodynamic (PK/PD) Results in Healthy Volunteers

Kelly Foster; Angela She; Rochelle M. Summerfelt; Brent Dickinson; Barrett Katz; Pawel Wiczling; Vahe Bedian

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4038.

ARVO Annual Meeting Abstract June 2023

Preclinical Pharmacokinetics of VRDN-003, A Next-Generation Half-life Extended Antibody to the IGF-1 Receptor for Thyroid Eye Disease

Brent Dickinson; Kelly Foster; Vahe Bedian

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4043.

ARVO Annual Meeting Abstract June 2022

Optic nerve degeneration due to complement activation in a combined glaucoma model

Kim Karla Schulte; Renée M. Girbig; Rudolf Fuchshofer; H. Bukhard Dick; Stephanie C Joachim; Sabrina Reinehr

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):926 – A0395.

ARVO Annual Meeting Abstract June 2022

Enhanced retinal ganglion cell loss is accompanied by microglia activation in a multifactorial glaucoma model

Sabrina Reinehr; Renée M. Girbig; Janine Theile; Rudolf Fuchshofer; H. Bukhard Dick; Stephanie C Joachim

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):922 – A0391.

ARVO Annual Meeting Abstract June 2022

Beneficial impact of primary RPE cells in a porcine organotypic co-cultivation model

Stephanie C Joachim; Natalie Wagner; Armin Safaei; Jose Hurst; Pia Vogt; Maurice R Gammel; H. Bukhard Dick; Sven Schnichels

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):797 – F0356.

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Brain-derived neurotrophic factor deficiency triggers early loss of retinal ganglion cells in mice

Optimized technique of the LIRIC (Laser-Induced-Refractive-Index-Change)-procedure for non-invasive, non-surgical correction of ametropia

Intermittent fasting reduces glaucomatous damage in an HSP27 autoimmune mouse model

Evaluating Oxidative Stress and Inflammatory Response in Porcine Corneas Following Laser-Induced Refractive Index Change (LIRIC)

Divergent Pathways in Optic Neuritis: Transcriptomic Insights into Demyelinating Disorder Models

The NLRP3 inflammasome mediates neurodegeneration in an ischemia-reperfusion injury model of acute angle-closure glaucoma

Early autophagy activation after retinal ischemia in mice

Phaco Longitudinal Mode Heat Generation, a Two-System Efficiency Comparison Study

Induced oxidative stress in ex vivo porcine corneas downregulates mRNA expression

Advanced age accelerates inflammation in mice with high-pressure glaucoma

Investigation of Inter- and Intra-Day Variability of Tear Fluid Regarding Flow Rate, Protein Concentration as well as Protein Composition

HPS27 induced glaucomatous damage in young and aged mice

Protection against oxidative stress by coenzyme Q10 in a porcine organculture

Novel multifactorial glaucoma mouse model exhibits retinal T-cell response

Preclinical Pharmacokinetics and Bioavailability of VRDN-002, a Next-Generation Half-Life Extended Antagonist Antibody to IGF-1 Receptor for Thyroid Eye Disease (TED)

VRDN-002, a Next-Generation Half-life Extended Antagonist Antibody to IGF-1 Receptor for Thyroid Eye Disease (TED): Safety and Pharmacokinetic/Pharmacodynamic (PK/PD) Results in Healthy Volunteers

Preclinical Pharmacokinetics of VRDN-003, A Next-Generation Half-life Extended Antibody to the IGF-1 Receptor for Thyroid Eye Disease

Optic nerve degeneration due to complement activation in a combined glaucoma model

Enhanced retinal ganglion cell loss is accompanied by microglia activation in a multifactorial glaucoma model

Beneficial impact of primary RPE cells in a porcine organotypic co-cultivation model

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