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ARVO Annual Meeting Abstract June 2022

Peptide-based immunotherapy against oxidized elastin ameliorates pathology in mouse model of smoke-induced ocular injury

Baerbel Rohrer; Nathaniel Parsons; Balasubramaniam Annamalai; Crystal Nicholson; Elisabeth Obert; Bryan W. Jones; Andrew D Dick

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4600 – F0392. doi:

ARVO Annual Meeting Abstract June 2022

Regulatable complement inhibition of the alternative pathway mitigates age-related macular degeneration pathology

Nathaniel Parsons; Baerbel Rohrer

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4596 – F0388. doi:

Retina April 2021

Subretinal Rather Than Intravitreal Adeno-Associated Virus–Mediated Delivery of a Complement Alternative Pathway Inhibitor Is Effective in a Mouse Model of RPE Damage

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Balasubramaniam Annamalai; Nathaniel Parsons; Crystal Nicholson; Elisabeth Obert; Bryan Jones; Bärbel Rohrer
TAGS: complement system proteins, familial hypercholesterolemia, family history, mice, adeno-associated virus
Invest. Ophthalmol. Vis. Sci.. 2021; 62(4):11. doi: https://doi.org/10.1167/iovs.62.4.11

Retina December 2020

Systemic Inflammation by Collagen-Induced Arthritis Affects the Progression of Age-Related Macular Degeneration Differently in Two Mouse Models of the Disease

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Gloriane Schnabolk; Elisabeth Obert; Nirmal K. Banda; Bärbel Rohrer

Invest. Ophthalmol. Vis. Sci.. 2020; 61(14):11. doi: https://doi.org/10.1167/iovs.61.14.11

ARVO Annual Meeting Abstract June 2020

Induction of antibodies against oxidized elastin exacerbates structural and functional damage in mouse models of age-related macular degeneration.

Baerbel Rohrer; Crystal Nicholson; Balasubramanian Annamalai; Sarah Stephenson; Carl Atkinson; Bryan W Jones; Nathaniel Parsons

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1115. doi:

ARVO Annual Meeting Abstract June 2020

Mice lacking the Vitamin A transporter RBPR2 show decreased Ocular Retinoid Content and Photoreceptor Phenotypes

GLENN LOBO; Elisabeth obert; Altaf A Kondkar; Ashish Solanki; Wayne Fitzgibbon; Deepak Nihalani; Baerbel Rohrer

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4010. doi:

Immunology and Microbiology March 2020

Immunization Against Oxidized Elastin Exacerbates Structural and Functional Damage in Mouse Model of Smoke-Induced Ocular Injury

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Balasubramaniam Annamalai; Crystal Nicholson; Nathaniel Parsons; Sarah Stephenson; Carl Atkinson; Bryan Jones; Bärbel Rohrer
TAGS: complement activation, elastin, immunization, mice, smoke, eye injuries, immunoglobulin g
Invest. Ophthalmol. Vis. Sci.. 2020; 61(3):45. doi: https://doi.org/10.1167/iovs.61.3.45

Clinical and Epidemiologic Research August 2019

Increased Nonexudative Age-Related Macular Degeneration Diagnosis Among Medicare Beneficiaries With Rheumatoid Arthritis

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Gloriane Schnabolk; Bärbel Rohrer; Kit N. Simpson
TAGS: age-related macular degeneration, nonexudative, medicare, rheumatoid arthritis, survival analysis, cohort studies, tumor necrosis factors
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3520-3526. doi: https://doi.org/10.1167/iovs.18-26444

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Increased Sodium Iodate-Induced Retinal Degeneration in the Presence of Systemic Inflammation Caused by Collagen-Induced Arthritis

Gloriane Schnabolk; Elisabeth Obert; Nirmal Banda; Baerbel Rohrer

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):782. doi:

ARVO Annual Meeting Abstract July 2019

Exosome-mediated long-range communication in stressed retinal pigment epithelial cell monolayers – focus on up-take mechanisms.

Baerbel Rohrer; Masakii Ishii; Crystal Nicholson; Carlene Brandon; Bala Annamalai; Navjot Shah

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1916. doi:

ARVO Annual Meeting Abstract July 2019

Importance of an essential ligand-binding domain in the vitamin A transporter Rbpr2 for proper eye development and photoreceptor cell survival in Zebrafish

GLENN LOBO; Ashish Solanki; altaf kondkar; Yanhui Su; Deepak Nihalani; Baerbel Rohrer

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2363. doi:

ARVO Annual Meeting Abstract July 2018

Systemic inflammation in a collagen-induced arthritis mouse model of rheumatoid arthritis leads to attenuated laser-induced choroidal neovascularization

Gloriane Schnabolk; Elisabeth Obert; Nirmal K. Banda; Baerbel Rohrer

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5559. doi:

ARVO Annual Meeting Abstract July 2018

Complement activation products, single nucleotide polymorphisms and age-related macular degeneration (AMD).

Baerbel Rohrer; ashley Frazer-Abel; Anthony Leonard; Rinki Ratnapriya; Tyson Ward; Alexandra Pietraszkiewicz; Elizabeth O’Quinn; Katherine Adams; Anand Swaroop; Bethany Wolf

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):792. doi:

ARVO Annual Meeting Abstract July 2018

Large-scale Whole-organism Phenotypic Screen Identifies Rod Cell Neuroprotectants Effective in Zebrafish and Mouse Models of Retinitis Pigmentosa

Liyun Zhang; Conan Chen; Jiang Qian; Hongkai Ji; Donald J Zack; Justin Hanes; David Ackerley; Baerbel Rohrer; Jeff S Mumm

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):980. doi:

Articles March 2018

Encapsulated Cell Technology-Based Delivery of a Complement Inhibitor Reduces Choroidal Neovascularization in a Mouse Model

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Balasubramaniam Annamalai; Nathaniel Parsons; Marwa Belhaj; Carlene Brandon; Jay Potts; Bärbel Rohrer
TAGS: choroidal neovascularization, complement inhibitor, familial hypercholesterolemia, family history, mice, technology, complement system proteins
Trans. Vis. Sci. Tech.. 2018; 7(2):3. doi: https://doi.org/10.1167/tvst.7.2.3

ARVO Annual Meeting Abstract June 2017

Increased age-related macular degeneration diagnosis among Medicare beneficiaries with rheumatoid arthritis

Gloriane Schnabolk; Baerbel Rohrer; Kit Simpson

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1517. doi:

ARVO Annual Meeting Abstract June 2017

Interactive Ca 2+ signaling in the RPE by anaphylatoxins

Olaf Strauss; Khava Abdusalamova; Christian Huber; Baerbel Rohrer; Catharina Busch

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2277. doi:

ARVO Annual Meeting Abstract June 2017

Anaphylatoxins activate Akt/PI3-kinase and FOXO1/FoxP3-signaling pathways in the retinal pigment epithelium

Catharina Busch; Balasubramaniam Annamalai; Maria Diedrichs-Möhring; Gerhild Wildner; Olaf Strauss; Baerbel Rohrer

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2278. doi:

ARVO Annual Meeting Abstract June 2017

Metabolic impacts of cigarette smoke on the retina of complement-compromised mice

Felix R Vazquez-Chona; Alexandra Butler; Emilie McKinnon; Baerbel Rohrer; Bryan W Jones

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2282. doi:

ARVO Annual Meeting Abstract June 2017

Mechanistic Insight into the Effects of the αCT1 Peptide on RPE Cell Integrity in Models of AMD

Elisabeth Obert; Gautam Ghatnekar; Robert Gourdie; Baerbel Rohrer

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3383. doi:

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Peptide-based immunotherapy against oxidized elastin ameliorates pathology in mouse model of smoke-induced ocular injury

Regulatable complement inhibition of the alternative pathway mitigates age-related macular degeneration pathology

Subretinal Rather Than Intravitreal Adeno-Associated Virus–Mediated Delivery of a Complement Alternative Pathway Inhibitor Is Effective in a Mouse Model of RPE Damage

Systemic Inflammation by Collagen-Induced Arthritis Affects the Progression of Age-Related Macular Degeneration Differently in Two Mouse Models of the Disease

Induction of antibodies against oxidized elastin exacerbates structural and functional damage in mouse models of age-related macular degeneration.

Mice lacking the Vitamin A transporter RBPR2 show decreased Ocular Retinoid Content and Photoreceptor Phenotypes

Immunization Against Oxidized Elastin Exacerbates Structural and Functional Damage in Mouse Model of Smoke-Induced Ocular Injury

Increased Nonexudative Age-Related Macular Degeneration Diagnosis Among Medicare Beneficiaries With Rheumatoid Arthritis

Increased Sodium Iodate-Induced Retinal Degeneration in the Presence of Systemic Inflammation Caused by Collagen-Induced Arthritis

Exosome-mediated long-range communication in stressed retinal pigment epithelial cell monolayers – focus on up-take mechanisms.

Importance of an essential ligand-binding domain in the vitamin A transporter Rbpr2 for proper eye development and photoreceptor cell survival in Zebrafish

Systemic inflammation in a collagen-induced arthritis mouse model of rheumatoid arthritis leads to attenuated laser-induced choroidal neovascularization

Complement activation products, single nucleotide polymorphisms and age-related macular degeneration (AMD).

Large-scale Whole-organism Phenotypic Screen Identifies Rod Cell Neuroprotectants Effective in Zebrafish and Mouse Models of Retinitis Pigmentosa

Encapsulated Cell Technology-Based Delivery of a Complement Inhibitor Reduces Choroidal Neovascularization in a Mouse Model

Increased age-related macular degeneration diagnosis among Medicare beneficiaries with rheumatoid arthritis

Interactive Ca 2+ signaling in the RPE by anaphylatoxins

Anaphylatoxins activate Akt/PI3-kinase and FOXO1/FoxP3-signaling pathways in the retinal pigment epithelium

Metabolic impacts of cigarette smoke on the retina of complement-compromised mice

Mechanistic Insight into the Effects of the αCT1 Peptide on RPE Cell Integrity in Models of AMD

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