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ARVO Annual Meeting Abstract June 2022

AAV-mediated anti-VEGF therapeutics increase corneal allograft survival-rate in a model of high-risk corneal transplantation

Evan Bilsbury; Wenqi Su; Shuo Sun; Sean Doherty; Emma Wood; Xiao Ke; Qiang Zheng; Phillip W.L. Tai; Haijiang Lin; Guangping Gao; Bo Tian

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):72 – A0045. doi:

ARVO Annual Meeting Abstract June 2022

Comparison of Adeno-Associated Virus Serotype Tropism in Human Retinal Explants and Non-Human Primates Retinal Explants

Emma Wood; shuo sun; Wenqi Su; Jun Xie; Ran He; Phillip W.L. Tai; Evan Bilsbury; Sean Doherty; Haijiang Lin; Guangping Gao; Bo Tian

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1792 – F0341. doi:

ARVO Annual Meeting Abstract June 2022

Transduction of self-complementary AAV in the Trabecular Meshwork and Anterior Chamber in mouse

Bo Tian; shuo sun; Wenqi Su; Abed Makhlouf; Ran He; Phillip W.L. Tai; Jun Xie; Guangping Gao; Haijiang Lin

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2824 – A0340. doi:

ARVO Annual Meeting Abstract June 2022

Overexpression of membrane bound Fas ligand accelerates inflammation in response to corneal alkali burns.

Sean Doherty; Wenqi Su; Shuo Sun; Evan Bilsbury; Emma Wood; Haijiang Lin; Ann Marshak-Rothstein; Bo Tian

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3236 – A0271. doi:

ARVO Annual Meeting Abstract June 2022

Gliosis in RPE65-associated inherited retinal degeneration

Abed Makhlouf; Wenqi Su; Shuo Sun; Haijiang Lin; Bo Tian

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3037 – F0408. doi:

ARVO Annual Meeting Abstract June 2022

Retinal pigment epithelium-derived 2’3’ cGAMP contributes to AMD progression

shuo sun; Wenqi Su; Ahmad Al Moujahed; Evan Bilsbury; Sean Doherty; Emma Wood; Abed Makhlouf; Bo Tian; Xiaorong Li; Haijiang Lin

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4620 – F0412. doi:

ARVO Annual Meeting Abstract June 2021

Inhibition of corneal neovascularization with rAAV-anti-VEGF in mouse corneal injury models

Wenqi Su; shuo sun; Bo Tian; Yongwen Luo; Jihye Ko; Phillip W.L. Tai; Xiao Ke; Qiang zheng; Hua Yan; Haijiang Lin; Guangping Gao

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):907. doi:

ARVO Annual Meeting Abstract June 2021

Low-dose rAAV-mediated inhibition of VEGF can treat neovascular pathologies without inducing retinal vasculitis

Shun-Yun cheng; Anneliese Malachi; Phillip W.L. Tai; Guangping Gao; Bo Tian; Haijiang Lin; Qiang zheng; Xiao Ke; Claudio Punzo

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1201. doi:

ARVO Annual Meeting Abstract June 2021

Suprachoroidal Injections of AAV for Retinal Gene Delivery in mouse

Bo Tian; Jun Xie; Wenqi Su; Shuo Sun; Qin Su; Guangping Gao; Haijiang Lin

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1177. doi:

ARVO Annual Meeting Abstract June 2021

Low-dose mTOR inhibitor alleviates RPE cellular senescence and pro-inflammation induced by accumulation of cytosolic nuclear DNA fragments

shuo sun; Wenqi Su; Haijiang Lin; Xiaorong Li; Bo Tian

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2961. doi:

ARVO Annual Meeting Abstract June 2020

STING mediates retinal lesion induced by cytosolic accumulation of damage DNA

Bo Tian; Hongtao Dong; Wenqi Su; Shuo Sun; Haijiang Lin

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3100. doi:

ARVO Annual Meeting Abstract June 2020

Abnormal mitochondrial dynamic correlats with the dysfunction of RPE phagocytosis in AMD

Haijiang Lin; Hongtao Dong; Wenqi Su; Shuo Sun; Bo Tian

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3542. doi:

ARVO Annual Meeting Abstract July 2018

The Role of Necroptosis Kinases in the Induction of iPSCs from Fibroblasts

Ahmad Al Moujahed; Bo Tian; Eleni Konstantinou; Haijiang Lin; Demetrios G. Vavvas

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4575. doi:

ARVO Annual Meeting Abstract July 2018

Damaged nuclear DNA accumulates in retinal pigment epithelium cells of age-related macular degeneration patients

Haijiang Lin; Bo Tian; ahmad Al-moujahed; Joan W Miller; Demetrios G. Vavvas

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):795. doi:

Glaucoma August 2017

Effects of Vitrectomy and Lensectomy on Older Rhesus Macaques: Oxygen Distribution, Antioxidant Status, and Aqueous Humor Dynamics

PDF

Carla J. Siegfried; Ying-Bo Shui; Baohe Tian; T. Michael Nork; Gregg A. Heatley; Paul L. Kaufman
TAGS: antioxidants, aqueous humor, macaca, macaca mulatta, oxygen, surgical procedures, operative, vitrectomy, vitreous body, eye, cercopithecidae
Invest. Ophthalmol. Vis. Sci.. 2017; 58(10):4003-4014. doi: https://doi.org/10.1167/iovs.17-21890

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Absent in Melanoma 2 (AIM2) Recognizes Cytosolic DNA and Mediates Inflammation in RPE Cells

Ahmad Al Moujahed; Bo Tian; Joan W Miller; Haijiang Lin; Demetrios G. Vavvas

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):601. doi:

ARVO Annual Meeting Abstract June 2017

Atorvastatin Promotes Phagocytosis and Attenuates Pro-Inflammatory Response in Human Retinal Pigment Epithelial Cells

Bo Tian; Ahmad Al Moujahed; Peggy Bouzika; Yijun Hu; Shoji Notomi; Pavlina Tsoka; Joan W Miller; Haijiang Lin; Demetrios G. Vavvas

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2279. doi:

ARVO Annual Meeting Abstract June 2017

Accumulation of damaged nDNA promotes RPE cellular senescence and pro-inflammation

Haijiang Lin; Bo Tian; Ahmad Al Moujahed; Joan W Miller; Demetrios G. Vavvas

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5235. doi:

Retina October 2015

A Novel ImageJ Macro for Automated Cell Death Quantitation in the Retina

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Daniel E. Maidana; Pavlina Tsoka; Bo Tian; Bernard Dib; Hidetaka Matsumoto; Keiko Kataoka; Haijiang Lin; Joan W. Miller; Demetrios G. Vavvas
TAGS: cell death, in situ nick-end labeling, retina, script, cell count
Invest. Ophthalmol. Vis. Sci.. 2015; 56(11):6701-6708. doi: https://doi.org/10.1167/iovs.15-17599

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Mitochondrial DNA acts as pro-inflammatory in AMD

Bernard Dib; Haijiang Lin; Daniel E. Maidana; John B Miller; Peggy Bouzika; Bo Tian; Joan W Miller; Demetrios Vavvas

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):799. doi:

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AAV-mediated anti-VEGF therapeutics increase corneal allograft survival-rate in a model of high-risk corneal transplantation

Comparison of Adeno-Associated Virus Serotype Tropism in Human Retinal Explants and Non-Human Primates Retinal Explants

Transduction of self-complementary AAV in the Trabecular Meshwork and Anterior Chamber in mouse

Overexpression of membrane bound Fas ligand accelerates inflammation in response to corneal alkali burns.

Gliosis in RPE65-associated inherited retinal degeneration

Retinal pigment epithelium-derived 2’3’ cGAMP contributes to AMD progression

Inhibition of corneal neovascularization with rAAV-anti-VEGF in mouse corneal injury models

Low-dose rAAV-mediated inhibition of VEGF can treat neovascular pathologies without inducing retinal vasculitis

Suprachoroidal Injections of AAV for Retinal Gene Delivery in mouse

Low-dose mTOR inhibitor alleviates RPE cellular senescence and pro-inflammation induced by accumulation of cytosolic nuclear DNA fragments

STING mediates retinal lesion induced by cytosolic accumulation of damage DNA

Abnormal mitochondrial dynamic correlats with the dysfunction of RPE phagocytosis in AMD

The Role of Necroptosis Kinases in the Induction of iPSCs from Fibroblasts

Damaged nuclear DNA accumulates in retinal pigment epithelium cells of age-related macular degeneration patients

Effects of Vitrectomy and Lensectomy on Older Rhesus Macaques: Oxygen Distribution, Antioxidant Status, and Aqueous Humor Dynamics

Absent in Melanoma 2 (AIM2) Recognizes Cytosolic DNA and Mediates Inflammation in RPE Cells

Atorvastatin Promotes Phagocytosis and Attenuates Pro-Inflammatory Response in Human Retinal Pigment Epithelial Cells

Accumulation of damaged nDNA promotes RPE cellular senescence and pro-inflammation

A Novel ImageJ Macro for Automated Cell Death Quantitation in the Retina

Mitochondrial DNA acts as pro-inflammatory in AMD

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