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ARVO Annual Meeting Abstract June 2024

A C3-targeting nanobody as a novel strategy to inhibit the complement system in cell and mouse models of Age-related macular degeneration (AMD)

Emilie Grarup Grarup Jensen; Thomas Stax Jakobsen; Gloriane Schnabolk; Kyrie Wilson; Nanna Jensen; Mathias Rask-Pedersen; Lars Aagaard; Steffen Thiel; Gregers Rom Andersen; Baerbel Rohrer; Anne Louise Askou; Thomas Corydon

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3803.

ARVO Annual Meeting Abstract June 2024

A novel small molecule reduces cell death and improves mitochondrial structure and function in models of genetic and age-related retinal degeneration

Baerbel Rohrer; Masaaki Ishii; Elisabeth O'Quinn; Christopher Charles Lindsey; Craig Beeson

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):206.

ARVO Annual Meeting Abstract June 2024

Mice Lacking the Systemic Retinol Transporter RBPR2 are Susceptible to Vitamin A Deficiencies and Display Reduced Cone Specific Visual Responses and Reduced Systemic Vitamin A

Glenn P Lobo; Rakesh Radhakrishnan; Baerbel Rohrer; Matthias Leung

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4649.

ARVO Annual Meeting Abstract June 2024

Complement and mitochondria in RPE cell function

Baerbel Rohrer

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6465.

ARVO Annual Meeting Abstract June 2023

Therapeutic potential of elastase inhibition in age-related macular degeneration (AMD)

Soumya Navneet; Baerbel Rohrer

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2095.

ARVO Annual Meeting Abstract June 2023

Oxidative stress tips the balance in favor of anaphylatoxin C5a receptor signaling triggering excessive mitochondrial fission instead of fusion in RPE cells.

Baerbel Rohrer; Masaaki Ishii

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4453.

ARVO Annual Meeting Abstract June 2022

Peptide-based immunotherapy against oxidized elastin ameliorates pathology in mouse model of smoke-induced ocular injury

Baerbel Rohrer; Nathaniel Parsons; Balasubramaniam Annamalai; Crystal Nicholson; Elisabeth Obert; Bryan W. Jones; Andrew D Dick

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4600 – F0392.

ARVO Annual Meeting Abstract June 2022

Regulatable complement inhibition of the alternative pathway mitigates age-related macular degeneration pathology

Nathaniel Parsons; Baerbel Rohrer

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4596 – F0388.

ARVO Annual Meeting Abstract June 2020

Induction of antibodies against oxidized elastin exacerbates structural and functional damage in mouse models of age-related macular degeneration.

Baerbel Rohrer; Crystal Nicholson; Balasubramanian Annamalai; Sarah Stephenson; Carl Atkinson; Bryan W Jones; Nathaniel Parsons

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1115.

ARVO Annual Meeting Abstract June 2020

Mice lacking the Vitamin A transporter RBPR2 show decreased Ocular Retinoid Content and Photoreceptor Phenotypes

GLENN LOBO; Elisabeth obert; Altaf A Kondkar; Ashish Solanki; Wayne Fitzgibbon; Deepak Nihalani; Baerbel Rohrer

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4010.

ARVO Annual Meeting Abstract July 2019

Increased Sodium Iodate-Induced Retinal Degeneration in the Presence of Systemic Inflammation Caused by Collagen-Induced Arthritis

Gloriane Schnabolk; Elisabeth Obert; Nirmal Banda; Baerbel Rohrer

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):782.

ARVO Annual Meeting Abstract July 2019

Exosome-mediated long-range communication in stressed retinal pigment epithelial cell monolayers – focus on up-take mechanisms.

Baerbel Rohrer; Masakii Ishii; Crystal Nicholson; Carlene Brandon; Bala Annamalai; Navjot Shah

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1916.

ARVO Annual Meeting Abstract July 2019

Importance of an essential ligand-binding domain in the vitamin A transporter Rbpr2 for proper eye development and photoreceptor cell survival in Zebrafish

GLENN LOBO; Ashish Solanki; altaf kondkar; Yanhui Su; Deepak Nihalani; Baerbel Rohrer

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2363.

ARVO Annual Meeting Abstract July 2018

Systemic inflammation in a collagen-induced arthritis mouse model of rheumatoid arthritis leads to attenuated laser-induced choroidal neovascularization

Gloriane Schnabolk; Elisabeth Obert; Nirmal K. Banda; Baerbel Rohrer

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5559.

ARVO Annual Meeting Abstract July 2018

Complement activation products, single nucleotide polymorphisms and age-related macular degeneration (AMD).

Baerbel Rohrer; ashley Frazer-Abel; Anthony Leonard; Rinki Ratnapriya; Tyson Ward; Alexandra Pietraszkiewicz; Elizabeth O’Quinn; Katherine Adams; Anand Swaroop; Bethany Wolf

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):792.

ARVO Annual Meeting Abstract July 2018

Large-scale Whole-organism Phenotypic Screen Identifies Rod Cell Neuroprotectants Effective in Zebrafish and Mouse Models of Retinitis Pigmentosa

Liyun Zhang; Conan Chen; Jiang Qian; Hongkai Ji; Donald J Zack; Justin Hanes; David Ackerley; Baerbel Rohrer; Jeff S Mumm

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):980.

ARVO Annual Meeting Abstract June 2017

Increased age-related macular degeneration diagnosis among Medicare beneficiaries with rheumatoid arthritis

Gloriane Schnabolk; Baerbel Rohrer; Kit Simpson

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1517.

ARVO Annual Meeting Abstract June 2017

Interactive Ca 2+ signaling in the RPE by anaphylatoxins

Olaf Strauss; Khava Abdusalamova; Christian Huber; Baerbel Rohrer; Catharina Busch

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2277.

ARVO Annual Meeting Abstract June 2017

Anaphylatoxins activate Akt/PI3-kinase and FOXO1/FoxP3-signaling pathways in the retinal pigment epithelium

Catharina Busch; Balasubramaniam Annamalai; Maria Diedrichs-Möhring; Gerhild Wildner; Olaf Strauss; Baerbel Rohrer

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2278.

ARVO Annual Meeting Abstract June 2017

Metabolic impacts of cigarette smoke on the retina of complement-compromised mice

Felix R Vazquez-Chona; Alexandra Butler; Emilie McKinnon; Baerbel Rohrer; Bryan W Jones

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2282.

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A C3-targeting nanobody as a novel strategy to inhibit the complement system in cell and mouse models of Age-related macular degeneration (AMD)

A novel small molecule reduces cell death and improves mitochondrial structure and function in models of genetic and age-related retinal degeneration

Mice Lacking the Systemic Retinol Transporter RBPR2 are Susceptible to Vitamin A Deficiencies and Display Reduced Cone Specific Visual Responses and Reduced Systemic Vitamin A

Complement and mitochondria in RPE cell function

Therapeutic potential of elastase inhibition in age-related macular degeneration (AMD)

Oxidative stress tips the balance in favor of anaphylatoxin C5a receptor signaling triggering excessive mitochondrial fission instead of fusion in RPE cells.

Peptide-based immunotherapy against oxidized elastin ameliorates pathology in mouse model of smoke-induced ocular injury

Regulatable complement inhibition of the alternative pathway mitigates age-related macular degeneration pathology

Induction of antibodies against oxidized elastin exacerbates structural and functional damage in mouse models of age-related macular degeneration.

Mice lacking the Vitamin A transporter RBPR2 show decreased Ocular Retinoid Content and Photoreceptor Phenotypes

Increased Sodium Iodate-Induced Retinal Degeneration in the Presence of Systemic Inflammation Caused by Collagen-Induced Arthritis

Exosome-mediated long-range communication in stressed retinal pigment epithelial cell monolayers – focus on up-take mechanisms.

Importance of an essential ligand-binding domain in the vitamin A transporter Rbpr2 for proper eye development and photoreceptor cell survival in Zebrafish

Systemic inflammation in a collagen-induced arthritis mouse model of rheumatoid arthritis leads to attenuated laser-induced choroidal neovascularization

Complement activation products, single nucleotide polymorphisms and age-related macular degeneration (AMD).

Large-scale Whole-organism Phenotypic Screen Identifies Rod Cell Neuroprotectants Effective in Zebrafish and Mouse Models of Retinitis Pigmentosa

Increased age-related macular degeneration diagnosis among Medicare beneficiaries with rheumatoid arthritis

Interactive Ca 2+ signaling in the RPE by anaphylatoxins

Anaphylatoxins activate Akt/PI3-kinase and FOXO1/FoxP3-signaling pathways in the retinal pigment epithelium

Metabolic impacts of cigarette smoke on the retina of complement-compromised mice

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