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ARVO Annual Meeting Abstract June 2020

IVMED 80 eye drops for treatment of keratoconus in patients -Phase 1/2a

Sarah Molokhia; Santosh Kumar Muddana; Haeli Hauritz; Yuting Qiu; Michael Burr; Arturo Chayet; Balamurali K Ambati

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2587. doi:

ARVO Annual Meeting Abstract June 2020

Subretinal Injection of AAVBR1 Targets the RPE and Outer Retina

Lara Carroll; Hironori Uehara; Xiaohui Zhang; Balamurali K Ambati

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2901. doi:

Cornea January 2020

Topical Pergolide Enhance Corneal Nerve Regrowth Following Induced Corneal Abrasion

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Xiaohui Zhang; Santosh Muddana; Sangeetha Ravi Kumar; Joshua Nelson Burton; Pratima Labroo; Jill Shea; Parker Stocking; Cornelia Siegl; Bonnie Archer; Jayant Agarwal; Balamurali K. Ambati
TAGS: cornea, pergolide, corneal abrasions, neurons
Invest. Ophthalmol. Vis. Sci.. 2020; 61(1):4. doi: https://doi.org/10.1167/iovs.61.1.4

Includes: Supplemental Content

Retinal Cell Biology August 2019

COMP-Ang1 Stabilizes Hyperglycemic Disruption of Blood-Retinal Barrier Phenotype in Human Retinal Microvascular Endothelial Cells

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Keith D. Rochfort; Lara S. Carroll; Peter Barabas; Timothy M. Curtis; Balamurali K. Ambati; Niall Barron; Philip M. Cummins
TAGS: angiotensin i, hyperglycemia, hyperglycemic agents, endothelial cells, blood-retinal barrier, phenotype
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3547-3555. doi: https://doi.org/10.1167/iovs.19-27644

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Systemic Delivery Of Endothelial Colony Forming Cells Enables Vascular Integration Into Diabetic Mouse retinas, But Not Diabetic Mouse Retinas Treated With AAV2.COMP-Ang1

Lara Carroll; Xiaohui Zhang; Yufeng Huang; Yuanyuan Wu; Alan W Stitt; Tim M Curtis; Reinhold J. Medina; Balamurali K Ambati

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2724. doi:

ARVO Annual Meeting Abstract July 2019

Gene therapy targeting PDGF-B for neovascular AMD

Xiaohui Zhang; Hironori Uehara; Lara Carroll; Bonnie Archer; Balamurali K Ambati

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2981. doi:

ARVO Annual Meeting Abstract July 2019

Soluble form TrkB, but not full-length TrkB, express in mouse cornea

Hironori Uehara; Bonnie Archer; Balamurali K Ambati

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3235. doi:

ARVO Annual Meeting Abstract July 2019

IVMED-85 eye drops for myopia control in guinea pigs

Sarah Molokhia; Haeli Hauritz; Bonnie Archer; Michael Burr; Leah A. Owen; Balamurali K Ambati

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5896. doi:

Retina June 2019

Intravitreal AAV2.COMP-Ang1 Attenuates Deep Capillary Plexus Expansion in the Aged Diabetic Mouse Retina

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Lara S. Carroll; Hironori Uehara; Daniel Fang; Susie Choi; Xiaohui Zhang; Malkit Singh; Zoya Sandhu; Philip M. Cummins; Tim M. Curtis; Alan W. Stitt; Bonnie J. Archer; Balamurali K. Ambati
TAGS: angiotensin i, blood capillaries, diabetes mellitus, mice, retina
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2494-2502. doi: https://doi.org/10.1167/iovs.18-26182

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Early Outcomes of Pulsed, Accelerated, Epithelial-On Crosslinking for Keratoconus

Sneha Konda; Balamurali K Ambati

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4393. doi:

ARVO Annual Meeting Abstract July 2018

Detection of early microvascular retinal changes in type I diabetic mice with OCT-Angiography

Hironori Uehara; Timilai Lesuna; Balamurali K Ambati

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5817. doi:

ARVO Annual Meeting Abstract July 2018

Effect of IVMED-80 on Human Cadaver Cornea Crosslinking

Santosh Kumar Kumar Muddana; Balamurali K Ambati; Hironori Uehara; Michael Burr; Sarah Molokhia

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4392. doi:

ARVO Annual Meeting Abstract July 2018

IVMED-80 Eye Drops for Treatment of Keratoconus

Sarah Molokhia; Santosh Kumar Kumar Muddana; Hironori Uehara; Michael Burr; Haeli hauritz; James McCulloch; Balamurali K Ambati

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4454. doi:

ARVO Annual Meeting Abstract July 2018

Efficacy and Safety of AAV2.Flt23k Intraceptor Compared to AAV2.sFlt01

Xiaohui Zhang; Hironori Uehara; Lara S Carroll; Bonnie Archer; Balamurali K Ambati

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1449. doi:

ARVO Annual Meeting Abstract July 2018

Intravitreal COMP-Ang1 reduces vascular area in advanced diabetic retinopathy.

Susie Choi; Lara S Carroll; Hironori Uehara; Malkit Singh; Balamurali K Ambati

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3572. doi:

Articles May 2017

Targeted Delivery of FLT-Morpholino Using Cyclic RGD Peptide

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Hironori Uehara; Santosh Kumar Muddana; Xiaohui Zhang; Subrata Kumar Das; Sai Bhuvanagiri; Jinlu Liu; Yuanyuan Wu; Susie Choi; Lara S. Carroll; Bonnie Archer; Balamurali K. Ambati

Trans. Vis. Sci. Tech.. 2017; 6(3):9. doi: https://doi.org/10.1167/tvst.6.3.9

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

Lens Capsule Biodegradable Lipid Implant for Sustained-Release Anti-VEGF Therapy of Neovascular AMD

Sarah Molokhia; Randon M Burr; Maggie Flood; Moritz Vallrath; Gerhard Winter; Balamurali Krishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4004. doi:

Cornea July 2014

Vimentin Knockdown Decreases Corneal Opacity

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Subrata K. Das; Isha Gupta; Yang Kyung Cho; Xiaohui Zhang; Hironori Uehara; Santosh Kumar Muddana; Ashlie A. Bernhisel; Bonnie Archer; Balamurali K. Ambati
TAGS: cornea, corneal opacity, mice, plasmids, vimentin
Invest. Ophthalmol. Vis. Sci.. 2014; 55(7):4030-4040. doi: https://doi.org/10.1167/iovs.13-13494

Multidisciplinary Ophthalmic Imaging June 2014

Angiographic Features of Transgenic Mice With Increased Expression of Human Serine Protease HTRA1 in Retinal Pigment Epithelium

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Sandeep Kumar; Zachary Berriochoa; Balamurali K Ambati; Yingbin Fu
TAGS: angiogram, htra1 gene, mice, mice, transgenic, ophthalmoscopy, retinal pigment epithelium, serine endopeptidases, polyps, animal model, phenotype
Invest. Ophthalmol. Vis. Sci.. 2014; 55(6):3842-3850. doi: https://doi.org/10.1167/iovs.13-13111

Genetics June 2014

FLT1 Genetic Variation Predisposes to Neovascular AMD in Ethnically Diverse Populations and Alters Systemic FLT1 Expression

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Leah A. Owen; Margaux A. Morrison; Jeeyun Ahn; Se Joon Woo; Hajime Sato; Rosann Robinson; Denise J. Morgan; Fani Zacharaki; Marina Simeonova; Hironori Uehara; Usha Chakravarthy; Ruth E. Hogg; Balamurali K. Ambati; Maria Kotoula; Wolfgang Baehr; Neena B. Haider; Giuliana Silvestri; Joan W. Miller; Evangelia E. Tsironi; Lindsay A. Farrer; Ivana K. Kim; Kyu Hyung Park; Margaret M. DeAngelis
TAGS: cohort studies, exudative age-related macular degeneration, genetics, single nucleotide polymorphism, vascular endothelial growth factor a
Invest. Ophthalmol. Vis. Sci.. 2014; 55(6):3543-3554. doi: https://doi.org/10.1167/iovs.14-14047

Includes: Supplemental Content

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IVMED 80 eye drops for treatment of keratoconus in patients -Phase 1/2a

Subretinal Injection of AAVBR1 Targets the RPE and Outer Retina

Topical Pergolide Enhance Corneal Nerve Regrowth Following Induced Corneal Abrasion

COMP-Ang1 Stabilizes Hyperglycemic Disruption of Blood-Retinal Barrier Phenotype in Human Retinal Microvascular Endothelial Cells

Systemic Delivery Of Endothelial Colony Forming Cells Enables Vascular Integration Into Diabetic Mouse retinas, But Not Diabetic Mouse Retinas Treated With AAV2.COMP-Ang1

Gene therapy targeting PDGF-B for neovascular AMD

Soluble form TrkB, but not full-length TrkB, express in mouse cornea

IVMED-85 eye drops for myopia control in guinea pigs

Intravitreal AAV2.COMP-Ang1 Attenuates Deep Capillary Plexus Expansion in the Aged Diabetic Mouse Retina

Early Outcomes of Pulsed, Accelerated, Epithelial-On Crosslinking for Keratoconus

Detection of early microvascular retinal changes in type I diabetic mice with OCT-Angiography

Effect of IVMED-80 on Human Cadaver Cornea Crosslinking

IVMED-80 Eye Drops for Treatment of Keratoconus

Efficacy and Safety of AAV2.Flt23k Intraceptor Compared to AAV2.sFlt01

Intravitreal COMP-Ang1 reduces vascular area in advanced diabetic retinopathy.

Targeted Delivery of FLT-Morpholino Using Cyclic RGD Peptide

Lens Capsule Biodegradable Lipid Implant for Sustained-Release Anti-VEGF Therapy of Neovascular AMD

Vimentin Knockdown Decreases Corneal Opacity

Angiographic Features of Transgenic Mice With Increased Expression of Human Serine Protease HTRA1 in Retinal Pigment Epithelium

FLT1 Genetic Variation Predisposes to Neovascular AMD in Ethnically Diverse Populations and Alters Systemic FLT1 Expression

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