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Articles March 2019

Latent Sensitization in a Mouse Model of Ocular Neuropathic Pain

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Jooyoung Cho; Nicholas Bell; Gregory Botzet; Paras Vora; Benjamin J. Fowler; Renee Donahue; Heather Bush; Bradley K. Taylor; Romulo J. C. Albuquerque
TAGS: hypersensitivity, neurons, wounds and injuries, cornea, eye, mice, neuropathic pain, sensitization
Trans. Vis. Sci. Tech.. 2019; 8(2):6. doi: https://doi.org/10.1167/tvst.8.2.6

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Non-integrated, reverse transcribed Alu complementary DNAs in Geographic Atrophy cause RPE toxicity

Shinichi Fukuda; Benjamin J Fowler; Tetsuhiro Yasuma; Akhil Varshney; Kameshwari Ambati; Nagaraj Kerur; Bradley Gelfand; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2456. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2018

Nucleoside reverse transcriptase inhibitors are broad-spectrum RPE protectants

Shuichiro Hirahara; Shinichi Fukuda; Younghee Kim; Reo Yasuma; Kameshwari Ambati; Junichi Fukuhara; Dongxu Fu; DAIPAYAN BANERJEE; Benjamin J Fowler; Tetsuhiro Yasuma; Nagaraj Kerur; Bradley Gelfand; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2459. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2018

Nucleoside reverse transcriptase inhibitors (NRTI) prevent inflammasome activation in retinal pigmented epithelium cells.

DAIPAYAN BANERJEE; Junichi Fukuhara; Dongxu Fu; Shinichi Fukuda; Shuichiro Hirahara; Younghee Kim; Benjamin J Fowler; Tetsuhiro Yasuma; Reo Yasuma; Kameshwari Ambati; Nagaraj Kerur; Bradley Gelfand; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2475. doi: https://doi.org/

ARVO Annual Meeting Abstract June 2017

Endogenous complementary DNA in age-related macular degeneration

Shinichi Fukuda; Tetsuhiro Yasuma; Benjamin J Fowler; Bradley D Gelfand; Nagaraj Kerur; Reo Yasuma; Brian Werner; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5262. doi: https://doi.org/

ARVO Annual Meeting Abstract September 2016

Nucleoside reverse transcriptase inhibitors are anti-inflammatory and inhibit poly I:C-induced retinal pigment epithelium degeneration

Shinichi Fukuda; Junichi Fukuhara; Younghee Kim; Benjamin Fowler; Tetsuhiro Yasuma; Reo Yasuma; Takako Fukuhara; Nagaraj Kerur; Bradley D Gelfand; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6551. doi: https://doi.org/

ARVO Annual Meeting Abstract September 2016

Nucleoside reverse transcriptase inhibitors attenuate amyloid-beta-induced retinal pigment epithelium degeneration

Takako Fukuhara; Junichi Fukuhara; Younghee Kim; Tetsuhiro Yasuma; Reo Yasuma; Benjamin Fowler; Shinichi Fukuda; Nagaraj Kerur; Bradley D Gelfand; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6552. doi: https://doi.org/

ARVO Annual Meeting Abstract September 2016

Non-canonical NLRP3 Inflammasome activation in Geographic Atrophy

Nagaraj Kerur; Younghee Kim; Shinichi Fukuda; Reo Yasuma; Ana Bastos-Carvalho; Daipayan Banerjee; Benjamin Fowler; Tetsuhiro Yasuma; Bradley D Gelfand; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):486. doi: https://doi.org/

ARVO Annual Meeting Abstract September 2016

Role of interferon signaling in Alu RNA-induced AMD

Daipayan Banerjee; Younghee Kim; Shinichi Fukuda; Reo Yasuma; Ana Bastos-Carvalho; Benjamin Fowler; Tetsuhiro Yasuma; Bradley D Gelfand; Nagaraj Kerur; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):487. doi: https://doi.org/

ARVO Annual Meeting Abstract September 2016

Nucleoside reverse transcriptase inhibitors prevent iron-induced retinal pigment epithelium cell death

Junichi Fukuhara; Younghee Kim; Tetsuhiro Yasuma; Reo Yasuma; Benjamin Fowler; Shinichi Fukuda; Takako Fukuhara; Nagaraj Kerur; Bradley D Gelfand; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5005. doi: https://doi.org/

Retinal Cell Biology November 2015

Nucleoside Reverse Transcriptase Inhibitors Suppress Laser-Induced Choroidal Neovascularization in Mice

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Takeshi Mizutani; Benjamin J. Fowler; Younghee Kim; Reo Yasuma; Laura A. Krueger; Bradley D. Gelfand; Jayakrishna Ambati
TAGS: vascular endothelial growth factor a, choroidal neovascularization, lasers, mice, nucleoside reverse transcriptase inhibitors, p2rx7 gene
Invest. Ophthalmol. Vis. Sci.. 2015; 56(12):7122-7129. doi: https://doi.org/10.1167/iovs.15-17440

ARVO Annual Meeting Abstract June 2015

Nucleoside reverse transcriptase inhibitor (NRTI) protection against iron cytotoxicity

Charles B Wright; Younghee Kim; Tetsuhiro Yasuma; Reo Yasuma; Shengjian Li; Benjamin J Fowler; Ana Bastos-Carvalho; Mark Ellsworth Kleinman; Jayakrishna Ambati; Bradley D Gelfand

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4211. doi: https://doi.org/

ARVO Annual Meeting Abstract June 2015

Next Generation Sequencing of Mobile Genetic Elements in Dry Age-Related Macular Degeneration

Mark Ellsworth Kleinman; Joel T Lowery; Chen Liu; Benjamin J Fowler; Dingyuan Lou; Subhash C Prajapati; Bradley D Gelfand; Mehdi Keddache; Jinze Liu; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4212. doi: https://doi.org/

ARVO Annual Meeting Abstract April 2014

Dideoxy-nucleosides are anti-inflammatory and inhibit RPE degeneration independent of reverse transcriptase inhibition

Benjamin Fowler; Younghee Kim; Yoshio Hirano; Nagaraj Kerur; Valeria Tarallo; Bradley D Gelfand; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1735. doi: https://doi.org/

ARVO Annual Meeting Abstract April 2014

Dual anti-angiogenic activity of Bevacizumab from its IgG1-Fc domain and VEGF neutralization

Takeshi Mizutani; Nagaraj Kerur; Shengjian Li; Younghee Kim; Reo Yasuma; Tetsuhiro Yasuma; Ana Bastos-Carvalho; Benjamin Fowler; Bradley D Gelfand; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1936. doi: https://doi.org/

ARVO Annual Meeting Abstract April 2014

Myd88 as a therapeutic target for choroidal neovascularization

Nagaraj Kerur; Younghee Kim; Yoshio Hirano; Valeria Tarallo; Ana Bastos-Carvalho; Benjamin Fowler; Tetsuhiro Yasuma; Reo Yasuma; Bradley D Gelfand; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2195. doi: https://doi.org/

ARVO Annual Meeting Abstract April 2014

Intravenous immunoglobulin treatment inhibits choroidal and corneal neovascularization via FcyR1

Reo Yasuma; Sasha Bogdanovich; Younghee Kim; Tetsuhiro Yasuma; Takeshi Mizutani; Ana Bastos-Carvalho; Benjamin Fowler; shengjian li; Bradley D Gelfand; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1190. doi: https://doi.org/

ARVO Annual Meeting Abstract April 2014

IL18 is not therapeutic for neovascular age-related macular degeneration

Bradley D Gelfand; Yoshio Hirano; Tetsuhiro Yasuma; Takeshi Mizutani; Benjamin J Fowler; Miho Nozaki; Hiroki Kaneko; Balamurali Ambati; David R Hinton; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3553. doi: https://doi.org/

ARVO Annual Meeting Abstract April 2014

Enhanced Alu RNA stability due to iron-mediated DICER1 impairment causes NLRP3 inflammasome priming

Charles B Wright; Younghee Kim; Tetsuhiro Yasuma; Shengjian Li; Benjamin J Fowler; Mark Ellsworth Kleinman; Jayakrishna Ambati; Bradley D Gelfand

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2187. doi: https://doi.org/

ARVO Annual Meeting Abstract April 2014

Mycobacterium tuberculosis secreted protein ESAT-6 activates the NLRP3 inflammasome in retinal pigment epithelium

Soumyava Basu; Nagaraj Kerur; Benjamin J Fowler; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2878. doi: https://doi.org/

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Latent Sensitization in a Mouse Model of Ocular Neuropathic Pain

Non-integrated, reverse transcribed Alu complementary DNAs in Geographic Atrophy cause RPE toxicity

Nucleoside reverse transcriptase inhibitors are broad-spectrum RPE protectants

Nucleoside reverse transcriptase inhibitors (NRTI) prevent inflammasome activation in retinal pigmented epithelium cells.

Endogenous complementary DNA in age-related macular degeneration

Nucleoside reverse transcriptase inhibitors are anti-inflammatory and inhibit poly I:C-induced retinal pigment epithelium degeneration

Nucleoside reverse transcriptase inhibitors attenuate amyloid-beta-induced retinal pigment epithelium degeneration

Non-canonical NLRP3 Inflammasome activation in Geographic Atrophy

Role of interferon signaling in Alu RNA-induced AMD

Nucleoside reverse transcriptase inhibitors prevent iron-induced retinal pigment epithelium cell death

Nucleoside Reverse Transcriptase Inhibitors Suppress Laser-Induced Choroidal Neovascularization in Mice

Nucleoside reverse transcriptase inhibitor (NRTI) protection against iron cytotoxicity

Next Generation Sequencing of Mobile Genetic Elements in Dry Age-Related Macular Degeneration

Dideoxy-nucleosides are anti-inflammatory and inhibit RPE degeneration independent of reverse transcriptase inhibition

Dual anti-angiogenic activity of Bevacizumab from its IgG1-Fc domain and VEGF neutralization

Myd88 as a therapeutic target for choroidal neovascularization

Intravenous immunoglobulin treatment inhibits choroidal and corneal neovascularization via FcyR1

IL18 is not therapeutic for neovascular age-related macular degeneration

Enhanced Alu RNA stability due to iron-mediated DICER1 impairment causes NLRP3 inflammasome priming

Mycobacterium tuberculosis secreted protein ESAT-6 activates the NLRP3 inflammasome in retinal pigment epithelium

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