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Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology June 2025

Biallelic NSUN3 Variants Cause Diverse Phenotypic Spectrum Disease: From Isolated Optic Atrophy to Severe Early-Onset Mitochondrial Disorder

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Neringa Jurkute; Heiko Brennenstuhl; Monika Kustermann; Lindsey Van Haute; Christian D. Mutti; Enrico Bugiardini; Takayuki Handa; Masaru Shimura; Axel Petzold; James Acheson; Anthony G. Robson; William L. Macken; Michael G. Hanna; Robert D. S. Pitceathly; Ashirwad Merve; Urania Kotzaeridou; Stefan Kölker; Michael Freilinger; Marcus Erdler; Reginald E. Bittner; Johannes A. Mayr; Yasushi Okazaki; Kei Murayama; Holger Prokisch; Andrew R. Webster; Michal Minczuk; Gavin Arno; Berthold Pemp; Georg F. Hoffmann; Wolfgang M. Schmidt; Patrick Yu-Wai-Man
TAGS: family, mitochondrial diseases, optic atrophy, phenotype, mitochondria, optic nerve disorders, respiratory chain
Invest. Ophthalmol. Vis. Sci.. 2025; 66(6):17. https://doi.org/10.1167/iovs.66.6.17

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Long-term safety of idebenone in patients with Leber hereditary optic neuropathy: Results from the PAROS study

Berthold Pemp; Thomas Klopstock; Xavier Llòria; Valerio Carelli

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):OD31.

ARVO Annual Meeting Abstract June 2022

Isolated dominant optic atrophy with childhood onset in a family with the heterozygous SDHA mutation c.1351C>T

Berthold Pemp; Wolfgang M Schmidt; Christoph Mitsch; Andreas Reitner

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):509 – A0086.

ARVO Annual Meeting Abstract July 2018

Changes in visual acuity in patients with chronic Leber hereditary optic neuropathy (LHON) during treatment with idebenone

Berthold Pemp; Karl Kircher; Andreas Reitner

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3357.

ARVO Annual Meeting Abstract April 2014

Measurements by Spectral Domain OCT in Papilledema are Associated with Reduced Retinal Nerve Fiber Layer Thickness after Resolution of Optic Disc Swelling

Berthold Pemp; Andreas Reitner; Karl Kircher; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5779.

ARVO Annual Meeting Abstract June 2013

Retinal morphometry changes observed in vivo measured with SD-OCT after pan-retinal photocoagulation in patients with proliferative diabetic retinopathy

Christoph Mitsch; Matthias Bolz; Berthold Pemp; Andreas Reitner; Christoph Scholda; Ursula Schmidt-Erfurth; Diabetic Retinopathy Research Group (DRRG) Vienna

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2432.

ARVO Annual Meeting Abstract June 2013

Changes of Choroidal Thickness as Measured with Spectral Domain OCT in Patients with Idiopathic Intracranial Hypertension after Lowering of Intracranial Pressure

Berthold Pemp; Karl Kircher; Andreas Reitner; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):4364.

ARVO Annual Meeting Abstract June 2013

Evaluating SAVE, a novel grading protocol for the treatment of diabetic macular edema

Sonja Prager; Matthias Bolz; Gabor Deak; Andreas Pollreisz; Berthold Pemp; Katharina Kriechbaum; Christoph Scholda; Ursula Schmidt-Erfurth; DRRG - Diabetic Retinopathy Research Group Vienna

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1238.

Clinical Trials March 2013

Role of Nitric Oxide in Optic Nerve Head Blood Flow Regulation during Isometric Exercise in Healthy Humans

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Doreen Schmidl; Agnes Boltz; Semira Kaya; Michael Lasta; Berthold Pemp; Gabriele Fuchsjager-Mayrl; Anton Hommer; Gerhard Garhofer; Leopold Schmetterer
TAGS: exercise, isometric, nitric oxide, omega-n-methylarginine, optic disk, placebos, regulation, vascular flow, phenylephrine, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2013; 54(3):1964-1970. https://doi.org/10.1167/iovs.12-11406

Clinical Trials January 2013

Neurovascular Dysfunction Precedes Neural Dysfunction in the Retina of Patients with Type 1 Diabetes

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Michael Lasta; Berthold Pemp; Doreen Schmidl; Agnes Boltz; Semira Kaya; Stefan Palkovits; Rene Werkmeister; Kinga Howorka; Alina Popa-Cherecheanu; Gerhard Garhöfer; Leopold Schmetterer
TAGS: diabetes mellitus, diabetes mellitus, type 1, electroretinography, pathophysiology, photopsia, retina, diabetes mellitus, type 2
Invest. Ophthalmol. Vis. Sci.. 2013; 54(1):842-847. https://doi.org/10.1167/iovs.12-10873

ARVO Annual Meeting Abstract March 2012

Choroidal Thickness in Patients with Papilledema due to Idiopathic Intracranial Hypertension Compared to Patients with Buried Optic Disc Drusen as Measured by Spectral Domain OCT

Berthold Pemp; Andreas Reitner; Karl Kircher; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3921.

ARVO Annual Meeting Abstract March 2012

Comparison Of Macular Pigment In Patients With Age-related Macular Degeneration And Healthy Control Subjects - A Study Using Spectral Fundus Reflectance

Semira Kaya; Guenther Weigert; Berthold Pemp; Stefan Sacu; Rene M. Werkmeister; Nikolaus Dragostinoff; Gerhard Garhofer; Ursula Schmidt-Erfurth; Leopold Schmetterer

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):5385.

Clinical Trials October 2011

Effects of Lutein Supplementation on Macular Pigment Optical Density and Visual Acuity in Patients with Age-Related Macular Degeneration

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Günther Weigert; Semira Kaya; Berthold Pemp; Stefan Sacu; Michael Lasta; René Marcel Werkmeister; Nikolaus Dragostinoff; Christian Simader; Gerhard Garhöfer; Ursula Schmidt-Erfurth; Leopold Schmetterer
TAGS: age-related macular degeneration, lutein, optics, pigment, visual acuity, placebos
Invest. Ophthalmol. Vis. Sci.. 2011; 52(11):8174-8178. https://doi.org/10.1167/iovs.11-7522

Clinical Trials June 2011

Effect of Latanoprost on Choroidal Blood Flow Regulation in Healthy Subjects

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Agnes Boltz; Doreen Schmidl; Günther Weigert; Michael Lasta; Berthold Pemp; Hemma Resch; Gerhard Garhöfer; Gabriele Fuchsjäger-Mayrl; Leopold Schmetterer
TAGS: intraocular pressure, latanoprost, placebos, regulation, vascular flow, suction drainage
Invest. Ophthalmol. Vis. Sci.. 2011; 52(7):4410-4415. https://doi.org/10.1167/iovs.11-7263

Retina May 2011

Response of Retinal Vessels and Retrobulbar Hemodynamics to Intravitreal Anti-VEGF Treatment in Eyes with Branch Retinal Vein Occlusion

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Stefan Sacu; Berthold Pemp; Günther Weigert; Gerlinde Matt; Gerhard Garhofer; Christian Pruente; Leopold Schmetterer; Ursula Schmidt-Erfurth
TAGS: anti-vascular endothelial growth factor therapy, eye, hemodynamics, ranibizumab, retinal vessels, venous retinal branch occlusion, edema, visual acuity, doppler color flow, doppler echocardiography
Invest. Ophthalmol. Vis. Sci.. 2011; 52(6):3046-3050. https://doi.org/10.1167/iovs.10-5842

ARVO Annual Meeting Abstract April 2011

A Double-masked Randomized Cross-over Study Comparing Of The Effect Of Latanoprost/timolol And Brimonidine/timolol Fixed Combination On Intraocular Pressure And Ocular Blood Flow

Anton B. Hommer; Philip Sperl; Berthold Pemp; Michael Lasta; Doreen Schmidl; Clemens Vass; Gerhard Garhöfer; Leopold Schmetterer

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):239.

ARVO Annual Meeting Abstract April 2011

Reproducibility of a New Algorithm for Retinal Nerve Fiber Layer Thickness Measurement Using Spectral Domain OCT in Healthy Subjects

Berthold Pemp; Karl Kircher; Ursula Schmidt-Erfurth; Andreas Reitner

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):1022.

ARVO Annual Meeting Abstract April 2011

A Study Investigating The Reproducibility Of Retinal Vessel Hemoglobin Oxygenation Saturation Measurements Using The Retinal Vessel Analyzer In Healthy Young Subjects

Michael Lasta; Agnes Boltz; Doreen Schmidl; Stefan Palkovits; Berthold Pemp; Semira Kaya; Gerhard Garhofer; Leopold Schmetterer

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):5637.

ARVO Annual Meeting Abstract April 2011

Effects Of Lutein Supplementation On Macular Pigment Optical Density And Visual Acuity In Patients With Age-related Macular Degeneration

Guenther Weigert; Semira Kaya; Berthold Pemp; Stefan Sacu; Michael Lasta; Rene M. Werkmeister; Nikolaus Dragostinoff; Gerhard Garhofer; Ursula Schmidt-Erfurth; Leopold Schmetterer

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):5658.

ARVO Annual Meeting Abstract April 2011

Optic Nerve Head Blood Flow Regulation during an Experimental Increase in Ocular Perfusion Pressure: Role of Nitric Oxide

Doreen Schmidl; Michael Lasta; Agnes Boltz; Berthold Pemp; Semira Kaya; Gerhard Garhofer; Gabriele Fuchsjaeger-Mayrl; Leopold Schmetterer

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):6053.

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Biallelic NSUN3 Variants Cause Diverse Phenotypic Spectrum Disease: From Isolated Optic Atrophy to Severe Early-Onset Mitochondrial Disorder

Long-term safety of idebenone in patients with Leber hereditary optic neuropathy: Results from the PAROS study

Isolated dominant optic atrophy with childhood onset in a family with the heterozygous SDHA mutation c.1351C>T

Changes in visual acuity in patients with chronic Leber hereditary optic neuropathy (LHON) during treatment with idebenone

Measurements by Spectral Domain OCT in Papilledema are Associated with Reduced Retinal Nerve Fiber Layer Thickness after Resolution of Optic Disc Swelling

Retinal morphometry changes observed in vivo measured with SD-OCT after pan-retinal photocoagulation in patients with proliferative diabetic retinopathy

Changes of Choroidal Thickness as Measured with Spectral Domain OCT in Patients with Idiopathic Intracranial Hypertension after Lowering of Intracranial Pressure

Evaluating SAVE, a novel grading protocol for the treatment of diabetic macular edema

Role of Nitric Oxide in Optic Nerve Head Blood Flow Regulation during Isometric Exercise in Healthy Humans

Neurovascular Dysfunction Precedes Neural Dysfunction in the Retina of Patients with Type 1 Diabetes

Choroidal Thickness in Patients with Papilledema due to Idiopathic Intracranial Hypertension Compared to Patients with Buried Optic Disc Drusen as Measured by Spectral Domain OCT

Comparison Of Macular Pigment In Patients With Age-related Macular Degeneration And Healthy Control Subjects - A Study Using Spectral Fundus Reflectance

Effects of Lutein Supplementation on Macular Pigment Optical Density and Visual Acuity in Patients with Age-Related Macular Degeneration

Effect of Latanoprost on Choroidal Blood Flow Regulation in Healthy Subjects

Response of Retinal Vessels and Retrobulbar Hemodynamics to Intravitreal Anti-VEGF Treatment in Eyes with Branch Retinal Vein Occlusion

A Double-masked Randomized Cross-over Study Comparing Of The Effect Of Latanoprost/timolol And Brimonidine/timolol Fixed Combination On Intraocular Pressure And Ocular Blood Flow

Reproducibility of a New Algorithm for Retinal Nerve Fiber Layer Thickness Measurement Using Spectral Domain OCT in Healthy Subjects

A Study Investigating The Reproducibility Of Retinal Vessel Hemoglobin Oxygenation Saturation Measurements Using The Retinal Vessel Analyzer In Healthy Young Subjects

Effects Of Lutein Supplementation On Macular Pigment Optical Density And Visual Acuity In Patients With Age-related Macular Degeneration

Optic Nerve Head Blood Flow Regulation during an Experimental Increase in Ocular Perfusion Pressure: Role of Nitric Oxide

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