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ARVO Annual Meeting Abstract June 2024

Electric Field Stimulation Collaborates with Ciliary Neurotrophic Factor to Direct Retinal Ganglion Cell Axon Regeneration After Optic Nerve Crush Injury

Connie Huang; Sasha Medvidovic; Timothy Kim; Gigi Niu; Anahit Simonyan; Pooyan Pahlavan; Ege Iseri; Vahini Garimella; Mahnaz Shahidi; Darrin Jason Lee; Biju Thomas; Derek S. Welsbie; Gianluca Lazzi; Kimberly K. Gokoffski

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):687.

ARVO Annual Meeting Abstract June 2024

Noninvasive Ultrasound Stimulation for Optic Nerve Protection and Whole RNA sequencing

chen gong; jie ji; Junhang Zhang; Biju Thomas; Mark S. Humayun; qianbin wang; Qifa Zhou

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3946.

ARVO Annual Meeting Abstract June 2024

Accelerated Retina Organoid Differentiation and Maturation through a Brief Exposure to Electrical Field

Deepthi S. Rajendran Nair; Ege Iseri; Andrea Shehi; Anika Gupta; Anagha Krishnagiri; Stella Quach; Tianyuan Wei; Magdalene J Seiler; Gianluca Lazzi; Biju Thomas

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4545.

ARVO Annual Meeting Abstract June 2023

Ultrasound Stimulation for Optic Nerve Reparation

Gengxi Lu; Chen Gong; Biju Thomas; Mark S Humayun; Qifa Zhou

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1990.

ARVO Annual Meeting Abstract June 2023

Electric Field Application and mTOR Activation Collaborate to Direct Optic Nerve Regeneration After Crush Injury

Timothy Kim; Sasha Medvidovic; Phillip Lam; Petcy Yao; Ege Iseri; Micalla Peng; Anahit Simonyan; Biju Thomas; Mahnaz Shahidi; Gianluca Lazzi; Kimberly Gokoffski

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1569.

ARVO Annual Meeting Abstract June 2023

Stem cell-derived retinal co-grafts repair permanent retinal damage in a rat model of laser injury

Deepthi S. Rajendran Nair; Magdalene J Seiler; Juan Carlos Martinez; Ruchi Sharma; Kapil Bharti; Mark S Humayun; Biju B Thomas

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1616.

ARVO Annual Meeting Abstract June 2023

Application of Electric Fields with Asymmetric Charge Balanced Waveforms Directs Optic Nerve Regeneration After Crush Injury

Sasha Medvidovic; Timothy Kim; Phillip Lam; Petcy Yao; Ege Iseri; Micalla Peng; Anahit Simonyan; Biju B Thomas; Mahnaz Shahidi; Gianluca Lazzi; Kimberly Gokoffski

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1565.

ARVO Annual Meeting Abstract June 2022

Electric Fields Direct Full-Length Optic Nerve Regeneration and Partial Restoration of Visual Function

Micalla Peng; Phillip Lam; Manjunath Machnoor; Javad Paknahad; Ege Iseri; Xiecheng Shao; Mahnaz Shahidi; Biju Thomas; Gianluca Lazzi; Kimberly Gokoffski

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1139.

ARVO Annual Meeting Abstract June 2022

Non-invasive ultrasound retinal stimulation for vision restoration and its frequency-dependent efficiency

Gengxi Lu; Xuejun Qian; Runze Li; Yushun Zeng; Biju Thomas; Mark S Humayun; Qifa Zhou

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4535 – F0322.

Retinal Cell Biology September 2020

Retina Organoid Transplants Develop Photoreceptors and Improve Visual Function in RCS Rats With RPE Dysfunction

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Bin Lin; Bryce T. McLelland; Robert B. Aramant; Biju B. Thomas; Gabriel Nistor; Hans S. Keirstead; Magdalene J. Seiler
TAGS: organoids, pathophysiology, photoreceptors, rats, rats, nude, retina, surgical procedures, operative, transplantation, vision, electroretinography
Invest. Ophthalmol. Vis. Sci.. 2020; 61(11):34. https://doi.org/10.1167/iovs.61.11.34

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

hESC-derived retina organoid sheet transplants develop photoreceptors, connect with the host retina and improve visual function in immunodeficient RCS rats

Magdalene J Seiler; Bin Lin; Bryce McLelland; Gabriel Nistor; Robert B Aramant; Biju Thomas; Hans Keirstead

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2889.

ARVO Annual Meeting Abstract July 2019

Co-grafted sheets of hESC derived retina organoids and RPE improve vision function in RCS rats

Bin Lin; Juan Carlos Martinez; Dan Hong Zhu; David R Hinton; Mark Humayun; Bryce McLelland; Robert Aramant; Magdalene J Seiler; Biju Thomas

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2890.

ARVO Annual Meeting Abstract July 2019

The effect of reduced oxygen delivery and metabolism on electroretinogram b-wave in rats

Nathanael Matei; James Burford; Sophie Leahy; Selin L Auvazian; Biju Thomas; Norman P Blair; Mahnaz Shahidi

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6077.

ARVO Annual Meeting Abstract July 2018

HLA-E-Expressing “Universal” Pluripotent Stem Cells as a Source of Retinal Pigment Epithelium to Treat Age-Related Macular Degeneration

mei jiang; Marta Stevanovic; Vanda Lopes; Biju Thomas; David Russell; Mark S. Humayun; Dennis O Clegg

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):539.

ARVO Annual Meeting Abstract July 2018

A Complete Retina Patch to Treat Irreversible Retinal Injuries

Biju Thomas; Bryce T McLelland; Danhong Zhu; Gabriel Nistor; Robert B Aramant; David R Hinton; Mark S. Humayun; Hans S Keirstead; Magdalene J Seiler

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):558.

Retinal Cell Biology May 2018

Transplanted hESC-Derived Retina Organoid Sheets Differentiate, Integrate, and Improve Visual Function in Retinal Degenerate Rats

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Bryce T. McLelland; Bin Lin; Anuradha Mathur; Robert B. Aramant; Biju B. Thomas; Gabriel Nistor; Hans S. Keirstead; Magdalene J. Seiler
TAGS: organoids, rats, rats, nude, retina, transplantation, vision, photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2018; 59(6):2586-2603. https://doi.org/10.1167/iovs.17-23646

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Survival and functionality of iPSC-RPE cultured as a polarized monolayer on ultrathin parylene assessed in a new immunodeficient RCS rat model

Biju Thomas; Yousuf Shad; Juan Carlos Martinez; Niharika Singh; Young Chang Kim; Seth Freeman; Sean Anthony Mu; Vishweshwer Shastri; Kapil Bharti; Mark S Humayun; David R Hinton; Danhong Zhu

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3263.

ARVO Annual Meeting Abstract June 2017

Retina organoids derived from hESCs and transplanted to immunodeficient RCS rats

Magdalene J Seiler; Bryce T McLelland; Anuradha Mathur; Bin Lin; Gabriel Nistor; Robert B Aramant; Biju Thomas; Hans S Keirstead

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4580.

ARVO Annual Meeting Abstract June 2017

Progressive changes in RCS rat retina during OCT/FAF-based in vivo imaging and their correlation with histological and visual functional analysis

Juan Carlos Martinez; Laura Liu; Juan Carlos Gutiérrez-Hernández; Alejandra Gonzalez Calle; Biju Thomas; Mark S Humayun

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):281.

Retina January 2017

Vision Recovery and Connectivity by Fetal Retinal Sheet Transplantation in an Immunodeficient Retinal Degenerate Rat Model

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Magdalene J. Seiler; Robert E. Lin; Bryce T. McLelland; Anuradha Mathur; Bin Lin; Jaclyn Sigman; Alexander T. De Guzman; Leonard M. Kitzes; Robert B. Aramant; Biju B. Thomas
TAGS: rats, nude, transplantation, vision, immunologic deficiency syndromes, eye, rats, fetus, retina
Invest. Ophthalmol. Vis. Sci.. 2017; 58(1):614-630. https://doi.org/10.1167/iovs.15-19028

Includes: Supplemental Content

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Electric Field Stimulation Collaborates with Ciliary Neurotrophic Factor to Direct Retinal Ganglion Cell Axon Regeneration After Optic Nerve Crush Injury

Noninvasive Ultrasound Stimulation for Optic Nerve Protection and Whole RNA sequencing

Accelerated Retina Organoid Differentiation and Maturation through a Brief Exposure to Electrical Field

Ultrasound Stimulation for Optic Nerve Reparation

Electric Field Application and mTOR Activation Collaborate to Direct Optic Nerve Regeneration After Crush Injury

Stem cell-derived retinal co-grafts repair permanent retinal damage in a rat model of laser injury

Application of Electric Fields with Asymmetric Charge Balanced Waveforms Directs Optic Nerve Regeneration After Crush Injury

Electric Fields Direct Full-Length Optic Nerve Regeneration and Partial Restoration of Visual Function

Non-invasive ultrasound retinal stimulation for vision restoration and its frequency-dependent efficiency

Retina Organoid Transplants Develop Photoreceptors and Improve Visual Function in RCS Rats With RPE Dysfunction

hESC-derived retina organoid sheet transplants develop photoreceptors, connect with the host retina and improve visual function in immunodeficient RCS rats

Co-grafted sheets of hESC derived retina organoids and RPE improve vision function in RCS rats

The effect of reduced oxygen delivery and metabolism on electroretinogram b-wave in rats

HLA-E-Expressing “Universal” Pluripotent Stem Cells as a Source of Retinal Pigment Epithelium to Treat Age-Related Macular Degeneration

A Complete Retina Patch to Treat Irreversible Retinal Injuries

Transplanted hESC-Derived Retina Organoid Sheets Differentiate, Integrate, and Improve Visual Function in Retinal Degenerate Rats

Survival and functionality of iPSC-RPE cultured as a polarized monolayer on ultrathin parylene assessed in a new immunodeficient RCS rat model

Retina organoids derived from hESCs and transplanted to immunodeficient RCS rats

Progressive changes in RCS rat retina during OCT/FAF-based in vivo imaging and their correlation with histological and visual functional analysis

Vision Recovery and Connectivity by Fetal Retinal Sheet Transplantation in an Immunodeficient Retinal Degenerate Rat Model

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