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ARVO Annual Meeting Abstract June 2024

A compact fundus image guided adaptive optics scanning laser ophthalmoscope (AOSLO) imaging system with active eye tracking designed for clinical use

ji ren; Qi Yin; Peng Fu; Kaiwen Li; Ruoyang Liu; Teng Zhang; Weixiao Fan; Kang Zhou; QIAN LIU; Bo Lei; Jin Yao; Jie Zhang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3397.

ARVO Annual Meeting Abstract June 2024

Novel variants in CLN3 associate respectively with juvenile neuron ceroid lipofuscinosis and isolated cone-rod dystrophy

Bo Lei; Ya Li

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4661.

Cornea & External Disease October 2023

Pathogenicity and Function Analysis of Two Novel SLC4A11 Variants in Patients With Congenital Hereditary Endothelial Dystrophy

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Tianjiao Zhen; Ya Li; Qingge Guo; Shun Yao; Ya You; Bo Lei
TAGS: apoptosis, endothelium, mitochondria, mitochondrial membranes, mutation, pathogenicity, proteins, plasmids, pathophysiology, transfection
Trans. Vis. Sci. Tech.. 2023; 12(10):1. https://doi.org/10.1167/tvst.12.10.1

ARVO Imaging in the Eye Conference Abstract June 2023

Choroidal Caverns in a Cohort of Patients with High Myopia

Xiaohong Guo; Bo Lei

Invest. Ophthalmol. Vis. Sci.. 2023; 64(9):PB0067.

ARVO Annual Meeting Abstract June 2023

Pathogenicity and functional analysis of CFAP410 mutations causing axial Spondylometaphyseal dysplasia with cone-rod dystrophy

Bo Lei; Shaoqing Yang

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4537.

ARVO Annual Meeting Abstract June 2023

Mitochondrial functional impairment in skin fibroblasts of patients with ARL3-related retinitis pigmentosa

Shun Yao; Bo Lei

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):244.

ARVO Annual Meeting Abstract June 2023

Multiple retinitis pigmentosa associated proteins are involved in retinal degeneration in a mouse model bearing a pde6 b mutation

Mingzhu Yang; Bo Lei

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1539.

ARVO Annual Meeting Abstract June 2022

A novel mutation located in the intermembrane space domain of AFG3L2 causes dominant optic atrophy through decreasing the stability of the encoded protein by ubiquitin-proteasome pathway

Lin Yang; jin xiuxiu; Bo Lei

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):982 – F0379.

ARVO Annual Meeting Abstract June 2021

Autosomal recessive rod-cone dystrophy associated with compound heterozygous variants in ARL3 gene

Bo Lei; Leming Fu

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1570.

Immunology and Microbiology June 2021

Retinal Pigment Epithelial Cells Express Antimicrobial Peptide Lysozyme – A Novel Mechanism of Innate Immune Defense of the Blood-Retina Barrier

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Jian Liu; Caijiao Yi; Wei Ming; Miao Tang; Xiao Tang; Chang Luo; Bo Lei; Mei Chen; Heping Xu
TAGS: muramidase, retinal pigment cell, antimicrobials, peptides
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):21. https://doi.org/10.1167/iovs.62.7.21

Articles April 2021

Association Between the Types of Posterior Staphyloma and Their Risk Factors in Pathological Myopia

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Guangqi An; Fangfang Dai; Rui Wang; Zhenhui Liu; Ju Guo; Meng Pan; Xuemin Jin; Bo Lei
TAGS: 3d mri, eye, myopia, risk factors, staphyloma, shape
Trans. Vis. Sci. Tech.. 2021; 10(4):5. https://doi.org/10.1167/tvst.10.4.5

ARVO Annual Meeting Abstract July 2019

Whole-exome sequencing identifies a novel homozygous missense variant in REEP6 gene in a retinitis pigmentosa patient complicated with macular hole

Bo Lei

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4489.

Retinal Cell Biology December 2018

Light-Induced Lipocalin 2 Facilitates Cellular Apoptosis by Positively Regulating Reactive Oxygen Species/Bim Signaling in Retinal Degeneration

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Wenyi Tang; Jun Ma; Ruiping Gu; Boya Lei; Xinyi Ding; Gezhi Xu
TAGS: apoptosis, lcn2 gene, lentivirus, lipocalin-2 protein, photoreceptors, reactive oxygen species, retina, retinal degeneration, signal transduction, protein overexpression
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):6014-6025. https://doi.org/10.1167/iovs.18-25213

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

The effects of exogenous and endogenous liver X receptor agonists on LPS-induced inflammation in human retinal pigment epithelium cells

Peng Yu; Yiguo Qiu; Lin Yang; Yuxin Mai; Bo Lei

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5323.

ARVO Annual Meeting Abstract July 2018

Attenuation of Intraocular Inflammatory Responses in Experimental Autoimmune Uveitis by TMP Is Associated with Modulating of the STAT3 and STAT4 Pathways

Bo Lei; Ru Lin

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5328.

Retina July 2017

Glucocorticoid-Induced Leucine Zipper Protects the Retina From Light-Induced Retinal Degeneration by Inducing Bcl-xL in Rats

PDF

Ruiping Gu; Wenyi Tang; Boya Lei; Xinyi Ding; Cheng Jiang; Gezhi Xu
TAGS: bcl-xl protein, glucocorticoids, leucine zippers, light exposure, opportunity for error, protein overexpression, rats, retina, retinal degeneration, wounds and injuries
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3656-3668. https://doi.org/10.1167/iovs.17-22116

Includes: Supplemental Content

Retinal Cell Biology June 2017

Overexpression of Angiotensin-Converting Enzyme 2 Ameliorates Amyloid β-Induced Inflammatory Response in Human Primary Retinal Pigment Epithelium

PDF

Xinyu Fu; Ru Lin; Yiguo Qiu; Peng Yu; Bo Lei
TAGS: amyloid, angiotensin-converting enzyme, cytokine, inflammation, inflammatory response, protein overexpression, proteins, rna, messenger, polymerase chain reaction, apoptosis
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3018-3028. https://doi.org/10.1167/iovs.17-21546

Physiology and Pharmacology January 2017

Glucocorticoid-Induced Leucine Zipper Suppresses ICAM-1 and MCP-1 Expression by Dephosphorylation of NF-κB p65 in Retinal Endothelial Cells

PDF

Ruiping Gu; Boya Lei; Chen Jiang; Gezhi Xu
TAGS: glucocorticoids, intercellular adhesion molecule 1, leucine zippers, monocyte chemoattractant protein-1, endothelial cells, protein overexpression, opportunity for error
Invest. Ophthalmol. Vis. Sci.. 2017; 58(1):631-641. https://doi.org/10.1167/iovs.16-20933

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

Amelioration of Amyloid β induced retinal inflammatory responses by a LXR agonist TO901317 is associated with inactivation of the NF-κB signaling and NLRP3 Inflammasome

Bo Lei; Chunyan Lei

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12)

ARVO Annual Meeting Abstract June 2015

Downregulating p22phox ameliorates inflammation in Angiotensin II induced oxidative stress by regulating MAPK and NF-κB pathways in ARPE-19 cells

Yiguo Qiu; Lifei Tao; Peizeng Yang; Qiuhong Li; Bo Lei

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):839.

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A compact fundus image guided adaptive optics scanning laser ophthalmoscope (AOSLO) imaging system with active eye tracking designed for clinical use

Novel variants in CLN3 associate respectively with juvenile neuron ceroid lipofuscinosis and isolated cone-rod dystrophy

Pathogenicity and Function Analysis of Two Novel SLC4A11 Variants in Patients With Congenital Hereditary Endothelial Dystrophy

Choroidal Caverns in a Cohort of Patients with High Myopia

Pathogenicity and functional analysis of CFAP410 mutations causing axial Spondylometaphyseal dysplasia with cone-rod dystrophy

Mitochondrial functional impairment in skin fibroblasts of patients with ARL3-related retinitis pigmentosa

Multiple retinitis pigmentosa associated proteins are involved in retinal degeneration in a mouse model bearing a pde6 b mutation

A novel mutation located in the intermembrane space domain of AFG3L2 causes dominant optic atrophy through decreasing the stability of the encoded protein by ubiquitin-proteasome pathway

Autosomal recessive rod-cone dystrophy associated with compound heterozygous variants in ARL3 gene

Retinal Pigment Epithelial Cells Express Antimicrobial Peptide Lysozyme – A Novel Mechanism of Innate Immune Defense of the Blood-Retina Barrier

Association Between the Types of Posterior Staphyloma and Their Risk Factors in Pathological Myopia

Whole-exome sequencing identifies a novel homozygous missense variant in REEP6 gene in a retinitis pigmentosa patient complicated with macular hole

Light-Induced Lipocalin 2 Facilitates Cellular Apoptosis by Positively Regulating Reactive Oxygen Species/Bim Signaling in Retinal Degeneration

The effects of exogenous and endogenous liver X receptor agonists on LPS-induced inflammation in human retinal pigment epithelium cells

Attenuation of Intraocular Inflammatory Responses in Experimental Autoimmune Uveitis by TMP Is Associated with Modulating of the STAT3 and STAT4 Pathways

Glucocorticoid-Induced Leucine Zipper Protects the Retina From Light-Induced Retinal Degeneration by Inducing Bcl-xL in Rats

Overexpression of Angiotensin-Converting Enzyme 2 Ameliorates Amyloid β-Induced Inflammatory Response in Human Primary Retinal Pigment Epithelium

Glucocorticoid-Induced Leucine Zipper Suppresses ICAM-1 and MCP-1 Expression by Dephosphorylation of NF-κB p65 in Retinal Endothelial Cells

Amelioration of Amyloid β induced retinal inflammatory responses by a LXR agonist TO901317 is associated with inactivation of the NF-κB signaling and NLRP3 Inflammasome

Downregulating p22phox ameliorates inflammation in Angiotensin II induced oxidative stress by regulating MAPK and NF-κB pathways in ARPE-19 cells

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