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ARVO Annual Meeting Abstract June 2025

The essential role of a basic Helix-Loop-Helix (bHLH) E-protein family member Tcf12 in retinal health

Bogale Aredo; Gizem Ulker-Yilmazer; Tian Yu; Emily Turpin; Dogan Can Kirman; Yu-guang He; Sara Ludwig; Eva Moresco; Bruce Beutler; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5550.

ARVO Annual Meeting Abstract June 2025

Exploring molecular mechanisms of Leishmanolysin Like Peptidase (Lmln)-deficiency-induced subretinal microglia activation and retinal neurodegeneration

Dogan Can Kirman; Bogale Aredo; Gizem Ulker-Yilmazer; Emily Turpin; Yu-guang He; Eva Moresco; Bruce Beutler; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5332.

ARVO Annual Meeting Abstract June 2025

Forward genetic analysis using OCT screening identifies mutations associated with inner retinal thinning in mice

Tian Yu; Bogale Aredo; Bryce Johnson; Dogan Can Kirman; Emily Turpin; Eva Moresco; Bruce Beutler; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4871.

ARVO Annual Meeting Abstract June 2025

A mutation in a ubiquitin ligase complex component leads to retinal thickening without dysmorphia.

Emily R Turpin; Gizem Ulker-Yilmazer; Bogale Aredo; Dogan Can Kirman; Tian Yu; Yu-guang He; Sara Ludwig; Eva Moresco; Bruce Beutler; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4279.

ARVO Annual Meeting Abstract June 2025

Cargo adapter protein Bicdl1 has an essential role in retinal health

Gizem Ulker-Yilmazer; Bogale Aredo; Dogan Can Kirman; Emily Turpin; Sangita Shrestha; Seher Yuksel; Tian Yu; Yu-guang He; Sara Ludwig; Eva Moresco; Bruce Beutler; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3831.

ARVO Annual Meeting Abstract June 2024

Zinc-metallopeptidase Lmln deficiency induces subretinal microglia activation and retinal neurodegeneration

Dogan Can Kirman; Bogale Aredo; Yeshumenesh Zegeye; Sangita Shrestha; Emily Turpin; Gizem Ulker Yilmazer; Seher Yuksel; Yu-Guang He; Sara Ludwig; Eva Moresco; Bruce A. Beutler; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1658.

ARVO Annual Meeting Abstract June 2024

Muller glia cell-specific activation of the Ephrin receptor-signaling pathway mediates recovery response in the mouse retina after light injury

Bogale Aredo; Ashwani Kumar; Chao Xing; Bo Chen; Yi Ding; Mark Henkemeyer; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5370.

ARVO Annual Meeting Abstract June 2024

A cargo adaptor protein with an essential role in retinal health

Gizem Ulker Yilmazer; Bogale Aredo; Dogan Can Kirman; Emily Turpin; Sangita Shrestha; Seher Yuksel; Yu-Guang He; Sara Ludwig; Eva Moresco; Bruce A. Beutler; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6052.

Retinal Cell Biology August 2023

Single Cell RNA Sequencing Analysis of Mouse Retina Identifies a Subpopulation of Muller Glia Involved in Retinal Recovery From Injury in the FCD-LIRD Model

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Bogale Aredo; Ashwani Kumar; Bo Chen; Chao Xing; Rafael L. Ufret-Vincenty
TAGS: mice, radial retinal glial cell, recovery of function, retina, wounds and injuries, focal cortical dysplasia, gene expression, rna-seq
Invest. Ophthalmol. Vis. Sci.. 2023; 64(11):2. https://doi.org/10.1167/iovs.64.11.2

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Exploring the use of forward genetics to search for novel genetic associations to glaucoma

Bogale Aredo; Dogan Can Kirman; Yeshumenesh Zegeye; Emily Turpin; Sara Ludwig; Bo Chen; Yi Ding; Eva Marie Moresco; Bruce Beutler; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1027.

ARVO Annual Meeting Abstract June 2023

Herc3 mutations lead to prominent retinal microglial/macrophage activation and retinal degeneration.

Yeshumenesh Zegeye; Bogale Aredo; Seher Yuksel; Emily Turpin; Sangita Shrestha; Sara Ludwig; Bruce Beutler; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1587.

ARVO Annual Meeting Abstract June 2023

Non-redundant role of a zinc-metallopeptidase in retinal homeostasis.

Dogan Can Kirman; Bogale Aredo; Yeshumenesh Zegeye; Seher Yuksel; Sangita Shrestha; Emily Turpin; Sara Ludwig; Bruce Beutler; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3877.

ARVO Annual Meeting Abstract June 2022

Differential response of Muller cells to retinal injury in the fundus camera-delivered light induced retinal degeneration (FCD-LIRD) model

Bogale Aredo; Bo Chen; Yi Ding; Cynthia X. Zhao; Ashwani Kumar; Chao Xing; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1367 – F0298.

ARVO Annual Meeting Abstract June 2022

Novel association to retinal homeostasis identified for a gene involved in ubiquitination and proteasomal degradation.

Yeshumenesh Zegeye; Bogale Aredo; Seher Yuksel; Cynthia X. Zhao; Sara Ludwig; Miao Tang; Xiaohong Li; Bruce A. Beutler; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1963 – F0381.

ARVO Annual Meeting Abstract June 2022

Deletion of a cholesteryl ester hydrolase leads to a progressive retinal degeneration in mice

Seher Yuksel; Bogale Aredo; Yeshumenesh Zegeye; Cynthia X. Zhao; Miao Tang; Xiaohong Li; Laurent Gautron; Sara Ludwig; Igor A Butovich; Bruce A. Beutler; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1952 – F0370.

ARVO Annual Meeting Abstract June 2021

Analysis of cell type-specific responses to retinal injury in the fundus camera delivered-light induced retinal degeneration (FCD-LIRD) model

Bogale Aredo; Bo Chen; Yi Ding; Cynthia Zhao; Ashwani Kumar; Chao Xing; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3120.

ARVO Annual Meeting Abstract June 2020

Forward genetic analysis combined with OCT and fundus photography identifies mutations leading to progressive outer retinal degeneration in C57BL/6J mice

Bogale Aredo; Bo Chen; Yi Ding; Yuanfei Zhu; Cynthia Zhao; Ashwani Kumar; Chao Xing; Stephen Lyon; Jamie Russell; Xiaohong Li; Miao Tang; Priscilla Anderton; Sara Ludwig; Eva Marie Moresco; Bruce Beutler; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1896.

Retinal Cell Biology September 2019

Mice With a Combined Deficiency of Superoxide Dismutase 1 ( Sod1 ), DJ-1 ( Park7 ), and Parkin ( Prkn ) Develop Spontaneous Retinal Degeneration With Aging

PDF

Yuanfei Zhu; Bogale Aredo; Bo Chen; Cynthia X. Zhao; Yu-Guang He; Rafael L. Ufret-Vincenty
TAGS: aging, mice, parkinson disease 7, autosomal recessive early-onset, retinal degeneration, park2 gene, sod1 gene, retina, superoxide dismutase 1
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3740-3751. https://doi.org/10.1167/iovs.19-27212

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Mice with a combined deficiency of SOD1, DJ-1 and Parkin develop spontaneous retinal degeneration with aging

Bogale Aredo; Bo Chen; Yuanfei Zhu; Cynthia X Zhao; Yu_Guang He; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4915.

ARVO Annual Meeting Abstract July 2019

Forward genetics: searching for novel genes essential to retinal development and homeostasis

Rafael Ufret-Vincenty; Bogale Aredo; Bo Chen; Yuanfei Zhu; Yi Ding; Cynthia X Zhao; Bruce Beutler

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6060.

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The essential role of a basic Helix-Loop-Helix (bHLH) E-protein family member Tcf12 in retinal health

Exploring molecular mechanisms of Leishmanolysin Like Peptidase (Lmln)-deficiency-induced subretinal microglia activation and retinal neurodegeneration

Forward genetic analysis using OCT screening identifies mutations associated with inner retinal thinning in mice

A mutation in a ubiquitin ligase complex component leads to retinal thickening without dysmorphia.

Cargo adapter protein Bicdl1 has an essential role in retinal health

Zinc-metallopeptidase Lmln deficiency induces subretinal microglia activation and retinal neurodegeneration

Muller glia cell-specific activation of the Ephrin receptor-signaling pathway mediates recovery response in the mouse retina after light injury

A cargo adaptor protein with an essential role in retinal health

Single Cell RNA Sequencing Analysis of Mouse Retina Identifies a Subpopulation of Muller Glia Involved in Retinal Recovery From Injury in the FCD-LIRD Model

Exploring the use of forward genetics to search for novel genetic associations to glaucoma

Herc3 mutations lead to prominent retinal microglial/macrophage activation and retinal degeneration.

Non-redundant role of a zinc-metallopeptidase in retinal homeostasis.

Differential response of Muller cells to retinal injury in the fundus camera-delivered light induced retinal degeneration (FCD-LIRD) model

Novel association to retinal homeostasis identified for a gene involved in ubiquitination and proteasomal degradation.

Deletion of a cholesteryl ester hydrolase leads to a progressive retinal degeneration in mice

Analysis of cell type-specific responses to retinal injury in the fundus camera delivered-light induced retinal degeneration (FCD-LIRD) model

Forward genetic analysis combined with OCT and fundus photography identifies mutations leading to progressive outer retinal degeneration in C57BL/6J mice

Mice With a Combined Deficiency of Superoxide Dismutase 1 ( Sod1 ), DJ-1 ( Park7 ), and Parkin ( Prkn ) Develop Spontaneous Retinal Degeneration With Aging

Mice with a combined deficiency of SOD1, DJ-1 and Parkin develop spontaneous retinal degeneration with aging

Forward genetics: searching for novel genes essential to retinal development and homeostasis

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