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ARVO Annual Meeting Abstract June 2021

Chronic Oxidative Stress in Primary Retinal Pigmented Epithelium Monolayers Increases Basolateral Exosome Release and Changes Both Exosome and Extracellular Matrix Proteomes

Belinda Hernandez; Mikael Klingeborn; Nikolai Skiba; Daniel Grigsby; Una Kelly; Martha Caday; Arvydas Maminishkis; TeddiJo Watkins; Sheldon S Miller; W. Daniel Stamer; Catherine Bowes Rickman

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):256. doi:

ARVO Annual Meeting Abstract July 2019

Systemic AAV delivery of complement regulator, Factor H Like-1 (FHL-1) impacts visual function.

Daniel Grigsby; Michael Landowski; Una Kelly; Mikael Klingeborn; Marybeth Groelle; Catherine Bowes Rickman

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5197. doi:

ARVO Annual Meeting Abstract July 2018

Dietary Cholesterol Contributes to Vision Loss in a Complement-Dysregulated AMD Mouse Model

Michael Landowski; Una L Kelly; Daniel Grigsby; Marybeth Groelle; Catherine Bowes Rickman

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):348. doi:

ARVO Annual Meeting Abstract July 2018

Exosome uptake is selective but not species or tissue-specific

Anna Figueroa; Nicole R. Congrove; Sara Ann Sillik; Doraid Tarek Sadideen; Torsten Falk; Catherine Bowes Rickman; Brian S McKay

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3993. doi:

Retinal Cell Biology February 2018

Effect of Anti-C5a Therapy in a Murine Model of Early/Intermediate Dry Age-Related Macular Degeneration

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Christopher B. Toomey; Michael Landowski; Mikael Klingeborn; Una Kelly; John Deans; Holly Dong; Ons Harrabi; Thomas Van Blarcom; Yik Andy Yeung; Ruslan Grishanin; John C. Lin; Daniel R. Saban; Catherine Bowes Rickman
TAGS: mice, antibodies, choroidal neovascularization, age-related macular degeneration, choroid
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):662-673. doi: https://doi.org/10.1167/iovs.17-23134

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Four-dimensional microscope-integrated optical coherence tomography (4D MIOCT) guidance in subretinal surgery

Karim Sleiman; Lejla Vajzovic; Oscar Carrasco-Zevallos; Mikael Klingeborn; Alexandria Dandridge; Christian Viehland; Catherine Bowes Rickman; Joseph A Izatt; Cynthia A Toth

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1190. doi:

ARVO Annual Meeting Abstract June 2017

Lipoprotein synthesis and deposition in the eye is regulated by the complement system and glycosaminoglycans (GAGs).

Una L Kelly; Michael Landowski; Nikolai Skiba; Jian Liu; Catherine Bowes Rickman

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5249. doi:

ARVO Annual Meeting Abstract September 2016

Effect of Complement Factor H Variants in Regulating AMD-like Pathologies In Vivo .

Michael Landowski; Jindong Ding; Mikael Klingeborn; Una Kelly; Marybeth Groelle; Catherine Bowes Rickman

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6526. doi:

ARVO Annual Meeting Abstract June 2015

Complement dysregulation exacerbates AMD-like phenotype in APOE4 transgenic mouse model of AMD

John R Deans; Christopher B Toomey; Una Kelly; Mikael Klingeborn; Catherine Bowes Rickman

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):831. doi:

ARVO Annual Meeting Abstract June 2015

Depletion of Very Long Chain Polyunsaturated Fatty Acids Causes Functional and Ultrastructural Changes in Photoreceptors Independent of Mutant ELOVL4 Expression

Martin-Paul Gameli Agbaga; Jindong Ding; Blake Hopiavuori; Feng Li; Richard Steven Brush; Radha Ayyagari; Catherine Bowes Rickman; Robert E Anderson; Retinal Cell Biology

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):34. doi:

ARVO Annual Meeting Abstract April 2014

The Apolipoprotein E4 Targeted Replacement (APOE4 TR) Mouse Model of Age-Related Macular Degeneration (AMD) Exhibits Anti-Retinal Autoreactivity

Albert H. Alhatem; Nataliya Lenchik; Sarka Beranova-Giorgianni; Mikael Klingeborn; David D New; Francesco Giorgianni; Ivan Gerling; Marko Radic; Catherine Bowes Rickman; Alessandro Iannaccone

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1173. doi:

ARVO Annual Meeting Abstract April 2014

Exogenous CFH Contributes to Complement Regulation in the Eyes of Cfh-Deficient Animals.

Michael J Landowski; Una L Kelly; Marybeth Groelle; Jindong Ding; Catherine Bowes Rickman

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1321. doi:

Articles December 2013

Dry Age-Related Macular Degeneration: Mechanisms, Therapeutic Targets, and Imaging

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Catherine Bowes Rickman; Sina Farsiu; Cynthia A. Toth; Mikael Klingeborn
TAGS: age-related macular degeneration, diagnostic imaging, drusen, eye, proteins, autophagy, retinal pigment cell, complement system proteins, photoreceptors, oxidative stress
Invest. Ophthalmol. Vis. Sci.. 2013; 54(14):ORSF68-ORSF80. doi: https://doi.org/10.1167/iovs.13-12757

ARVO Annual Meeting Abstract June 2013

Human Complement Factor H (CFH) Transgene Expression Rescues the Visual Function and Retina Abnormalities in Aged cfh-/- Mice

Jindong Ding; Una Kelly; Marybeth Groelle; Catherine Bowes Rickman

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):5015. doi:

ARVO Annual Meeting Abstract June 2013

Oxidative Stress Significantly Increases Expression of Inflammatory and Antioxidant Markers in Complement Factor H Deficient Mice Compared to Wild-Type Mice

Terry Singhapricha; Una Kelly; Michael Landowski; Marybeth Groelle; Peter Saloupis; Catherine Bowes Rickman

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):364. doi:

ARVO Annual Meeting Abstract March 2012

Effect of Excess Complement Activation on AMD-like Pathology in the APOE4/cfh Knockout Transgenic Murine Model: Does Loss-of-function Exacerbate Retinal Disease?

Joseph G. Christenbury; Jin-Dong Ding; Una Kelly; Marybeth Groelle; Catherine Bowes Rickman

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1641. doi:

ARVO Annual Meeting Abstract March 2012

Properdin and Malondialdehyde (MDA) effects on the APOE4 mouse model of Age-Related Macula Degeneration (AMD)

Una L. Kelly; Marybeth Groelle; Jindong Ding; Wen-Chao Song; Catherine Bowes Rickman

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6466. doi:

ARVO Annual Meeting Abstract April 2011

Development and Characterization of Humanized Complement Factor H (CFH) Transgenic Mice

Jindong Ding; Una Kelly; Stephanie G. Smith; Marybeth Groelle; Catherine Bowes Rickman

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):958. doi:

ARVO Annual Meeting Abstract April 2011

Laminin β1 upregulation in Pseudoexfoliation syndrome

Pratap Challa; Anna H. Bordelon; Guorong Li; Catherine Bowes Rickman; David L. Epstein; Pedro Gonzalez

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):72. doi:

ARVO Annual Meeting Abstract April 2011

Morphometric Investigation of Human Retinal Pigment Epithelium (RPE) Flat Mounts: The Good, The Bad and The Ugly

Stephanie G. Smith; Jindong Ding; Sina Farsiu; Melody Chan; Catherine Bowes Rickman

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):1761. doi:

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Chronic Oxidative Stress in Primary Retinal Pigmented Epithelium Monolayers Increases Basolateral Exosome Release and Changes Both Exosome and Extracellular Matrix Proteomes

Systemic AAV delivery of complement regulator, Factor H Like-1 (FHL-1) impacts visual function.

Dietary Cholesterol Contributes to Vision Loss in a Complement-Dysregulated AMD Mouse Model

Exosome uptake is selective but not species or tissue-specific

Effect of Anti-C5a Therapy in a Murine Model of Early/Intermediate Dry Age-Related Macular Degeneration

Four-dimensional microscope-integrated optical coherence tomography (4D MIOCT) guidance in subretinal surgery

Lipoprotein synthesis and deposition in the eye is regulated by the complement system and glycosaminoglycans (GAGs).

Effect of Complement Factor H Variants in Regulating AMD-like Pathologies In Vivo .

Complement dysregulation exacerbates AMD-like phenotype in APOE4 transgenic mouse model of AMD

Depletion of Very Long Chain Polyunsaturated Fatty Acids Causes Functional and Ultrastructural Changes in Photoreceptors Independent of Mutant ELOVL4 Expression

The Apolipoprotein E4 Targeted Replacement (APOE4 TR) Mouse Model of Age-Related Macular Degeneration (AMD) Exhibits Anti-Retinal Autoreactivity

Exogenous CFH Contributes to Complement Regulation in the Eyes of Cfh-Deficient Animals.

Dry Age-Related Macular Degeneration: Mechanisms, Therapeutic Targets, and Imaging

Human Complement Factor H (CFH) Transgene Expression Rescues the Visual Function and Retina Abnormalities in Aged cfh-/- Mice

Oxidative Stress Significantly Increases Expression of Inflammatory and Antioxidant Markers in Complement Factor H Deficient Mice Compared to Wild-Type Mice

Effect of Excess Complement Activation on AMD-like Pathology in the APOE4/cfh Knockout Transgenic Murine Model: Does Loss-of-function Exacerbate Retinal Disease?

Properdin and Malondialdehyde (MDA) effects on the APOE4 mouse model of Age-Related Macula Degeneration (AMD)

Development and Characterization of Humanized Complement Factor H (CFH) Transgenic Mice

Laminin β1 upregulation in Pseudoexfoliation syndrome

Morphometric Investigation of Human Retinal Pigment Epithelium (RPE) Flat Mounts: The Good, The Bad and The Ugly

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