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ARVO Annual Meeting Abstract April 2010

Targeted Sequence Capture and Next Generation Sequencing of a 5Mb Region on Chromosome 15q Previously Linked to Keratoconus

C. E. Willoughby; D. P. Dash; G. Silvestri; J. Jackson; D. G. Frazer; A. E. Hughes; D. A. C. Simpson

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):4644.

ARVO Annual Meeting Abstract April 2009

The Effect of Brimonidine in IOP Spike Prophylaxis After Argon Laser Trabeculoplasty or Selective Laser Trabeculoplasty Procedures in Chronic vs. Non-Chronic Users of Brimonidine

C. D. Simpson; B. A. Hughes; M. S. Juzych; A. Goyal; M. Y. Alexander; S. D. Wolfe; C. Kim

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):160.

ARVO Annual Meeting Abstract April 2009

The Effect of a Microsurgical Training Course on Resident Performed Cataract Surgery Outcomes

A. R. Anchala; C. D. Simpson; J. Yonker

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):5587.

Retinal Cell Biology January 2009

Advanced Glycation End Product (AGE) Accumulation on Bruch’s Membrane: Links to Age-Related RPE Dysfunction

PDF

Josephine V. Glenn; Helen Mahaffy; Keqiang Wu; Gill Smith; Ryoji Nagai; David A. C. Simpson; Michael E. Boulton; Alan W. Stitt
TAGS: age, bruch's basal membrane, glycosylation end products, advanced, pathophysiology, rna, messenger, lipofuscin, polymerase chain reaction, enzyme activity
Invest. Ophthalmol. Vis. Sci.. 2009; 50(1):441-451. https://doi.org/10.1167/iovs.08-1724

ARVO Annual Meeting Abstract May 2008

Modeling Aberrant Splicing in Mutant Bardet-Biedl Syndrome (BBS) Genes

D. O'Prey; D. A. C. Simpson; P. L. Beales; C. E. Willoughby

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):1719.

Biochemistry and Molecular Biology September 2007

Prediction and Verification of miRNA Expression in Human and Rat Retinas

PDF

Amit Arora; Gareth J. McKay; David A. C. Simpson
TAGS: micrornas, retina
Invest. Ophthalmol. Vis. Sci.. 2007; 48(9):3962-3967. https://doi.org/10.1167/iovs.06-1221

Includes: Supplemental Content

ARVO Annual Meeting Abstract May 2007

Retinal MicroRNA Prediction and Verification: A Novel Method Based on Target Gene Expression

A. Arora; D. A. C. Simpson

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):3776.

ARVO Annual Meeting Abstract May 2007

Validation of Alternative Splicing Events Predicted by Computational Scoring of Splice Site Strength in Transcripts Associated With Inherited Retinal Degeneration

C. E. Willoughby; D. O'Prey; D. A. C. Simpson

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):3803.

Retinal Cell Biology December 2006

Rod Photoreceptor Loss in Rho −/− Mice Reduces Retinal Hypoxia and Hypoxia-Regulated Gene Expression

PDF

Tanyth E. de Gooyer; Kathryn A. Stevenson; Pete Humphries; David A. C. Simpson; Timothy M. Curtis; Tom A. Gardiner; Alan W. Stitt
TAGS: gene expression, hypoxia, mice, rod photoreceptors, retina
Invest. Ophthalmol. Vis. Sci.. 2006; 47(12):5553-5560. https://doi.org/10.1167/iovs.06-0646

Retinal Cell Biology December 2006

Retinopathy Is Reduced during Experimental Diabetes in a Mouse Model of Outer Retinal Degeneration

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Tanyth E. de Gooyer; Kathryn A. Stevenson; Pete Humphries; David A. C. Simpson; Tom A. Gardiner; Alan W. Stitt
TAGS: diabetes mellitus, diabetes mellitus, type 2, mice, retinal degeneration, retinal diseases, retina, hypoxia
Invest. Ophthalmol. Vis. Sci.. 2006; 47(12):5561-5568. https://doi.org/10.1167/iovs.06-0647

ARVO Annual Meeting Abstract May 2006

Retinopathy Is Reduced During Experimental Diabetes in a Mouse Model of Retinitis Pigmentosa

A.W. Stitt; T.A. Gardiner; K.A. Stevenson; P. Humphries; D.A. C. Simpson; T.E. de Gooyer

Invest. Ophthalmol. Vis. Sci.. 2006; 47(13):2577.

ARVO Annual Meeting Abstract May 2006

Targeted Deletion of the Basic Helix–Loop–Helix (bHLH) Transcription Factor Nhlh2 in Mouse Affects Cone Photoreceptors

M. Dellett; K.A. Stevenson; J.H. P. Brogan; D.A. C. Simpson; T. Cogliati

Invest. Ophthalmol. Vis. Sci.. 2006; 47(13):2774.

ARVO Annual Meeting Abstract May 2006

Assessment of Major Age–Telated Macular Degeneration Susceptibility Loci in Age–Related Ophthalmic Disorders

G.J. McKay; G. Young; D. Patel; D.A. C. Simpson; C.C. Patterson; G. Silvestri

Invest. Ophthalmol. Vis. Sci.. 2006; 47(13):3265.

ARVO Annual Meeting Abstract May 2005

Contribution of Rod Photoreceptor Loss to the Reduction of Retinal Hypoxia and Hypoxia–Regulated Gene Expression in Rho–/– Mice

T.E. de Gooyer; K.A. Stevenson; P. Humphries; D.A. C. Simpson; T.A. Gardiner; A.W. Stitt

Invest. Ophthalmol. Vis. Sci.. 2005; 46(13):1667.

ARVO Annual Meeting Abstract May 2005

Use of Comparative Genomics to Facilitate Identification of Mutational Hotspots for Development of an RP Genotyping Array

G.J. McKay; A. Arora; S.K. Todd; G. Silvestri; D.A. C. Simpson

Invest. Ophthalmol. Vis. Sci.. 2005; 46(13):1811.

Retina January 2005

Pigmented Paravenous Chorioretinal Atrophy Is Associated with a Mutation within the Crumbs Homolog 1 ( CRB1 ) Gene

PDF

Gareth J. McKay; Stephen Clarke; Jason A. Davis; David A. C. Simpson; Giuliana Silvestri
TAGS: atrophy, genes, mutation, family
Invest. Ophthalmol. Vis. Sci.. 2005; 46(1):322-328. https://doi.org/10.1167/iovs.04-0734

ARVO Annual Meeting Abstract May 2004

IDENTIFICATION OF ION CHANNELS IN RETINAL PIGMENT EPITHELIUM USING cDNA MICROARRAYS

K. Martin; T.M. Curtis; D.A. C. Simpson

Invest. Ophthalmol. Vis. Sci.. 2004; 45(13):3687.

ARVO Annual Meeting Abstract May 2004

Mutation studies of CRB1 and other genes in pigmented paravenous retinochoroidal atrophy (PPRCA)

G.J. McKay; S. Clarke; G. Silvestri; D.A. C. Simpson

Invest. Ophthalmol. Vis. Sci.. 2004; 45(13):4732.

ARVO Annual Meeting Abstract May 2004

Effects of loss of Nhlh1 and Nhlh2 basic helix–loop–helix (bHLH) transcription factors on retinal development

T. Cogliati; P. Delgado–Romero; K. Stevenson; D.A. C. Simpson; I.R. Kirsch

Invest. Ophthalmol. Vis. Sci.. 2004; 45(13):5320.

Retinal Cell Biology February 2003

Role of Vascular Endothelial Growth Factor and Placental Growth Factors During Retinal Vascular Development and Hyaloid Regression

PDF

Susan A. Feeney; David A. C. Simpson; Thomas A. Gardiner; Cliona Boyle; Pamela Jamison; Alan W. Stitt
TAGS: growth factor, placenta growth factor, vascular endothelial growth factor a, retina, placenta, antibodies, mice
Invest. Ophthalmol. Vis. Sci.. 2003; 44(2):839-847. https://doi.org/10.1167/iovs.02-0040

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Targeted Sequence Capture and Next Generation Sequencing of a 5Mb Region on Chromosome 15q Previously Linked to Keratoconus

The Effect of Brimonidine in IOP Spike Prophylaxis After Argon Laser Trabeculoplasty or Selective Laser Trabeculoplasty Procedures in Chronic vs. Non-Chronic Users of Brimonidine

The Effect of a Microsurgical Training Course on Resident Performed Cataract Surgery Outcomes

Advanced Glycation End Product (AGE) Accumulation on Bruch’s Membrane: Links to Age-Related RPE Dysfunction

Modeling Aberrant Splicing in Mutant Bardet-Biedl Syndrome (BBS) Genes

Prediction and Verification of miRNA Expression in Human and Rat Retinas

Retinal MicroRNA Prediction and Verification: A Novel Method Based on Target Gene Expression

Validation of Alternative Splicing Events Predicted by Computational Scoring of Splice Site Strength in Transcripts Associated With Inherited Retinal Degeneration

Rod Photoreceptor Loss in Rho −/− Mice Reduces Retinal Hypoxia and Hypoxia-Regulated Gene Expression

Retinopathy Is Reduced during Experimental Diabetes in a Mouse Model of Outer Retinal Degeneration

Retinopathy Is Reduced During Experimental Diabetes in a Mouse Model of Retinitis Pigmentosa

Targeted Deletion of the Basic Helix–Loop–Helix (bHLH) Transcription Factor Nhlh2 in Mouse Affects Cone Photoreceptors

Assessment of Major Age–Telated Macular Degeneration Susceptibility Loci in Age–Related Ophthalmic Disorders

Contribution of Rod Photoreceptor Loss to the Reduction of Retinal Hypoxia and Hypoxia–Regulated Gene Expression in Rho–/– Mice

Use of Comparative Genomics to Facilitate Identification of Mutational Hotspots for Development of an RP Genotyping Array

Pigmented Paravenous Chorioretinal Atrophy Is Associated with a Mutation within the Crumbs Homolog 1 ( CRB1 ) Gene

IDENTIFICATION OF ION CHANNELS IN RETINAL PIGMENT EPITHELIUM USING cDNA MICROARRAYS

Mutation studies of CRB1 and other genes in pigmented paravenous retinochoroidal atrophy (PPRCA)

Effects of loss of Nhlh1 and Nhlh2 basic helix–loop–helix (bHLH) transcription factors on retinal development

Role of Vascular Endothelial Growth Factor and Placental Growth Factors During Retinal Vascular Development and Hyaloid Regression

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