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ARVO Annual Meeting Abstract June 2023

Intravitreal (IVT) CITED2 peptide attenuates early stages not late stages of Neovascularization in the Oxygen Induced Retinopathy (OIR) in Mice.

Eunice Cheung; Krunal Patel; Gabor Halasz; Jingtai Cao; Carl Romano; Botir T Sagdullaev

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4889.

Retina October 2022

Evaluation of Molecular Properties versus In Vivo Performance of Aflibercept, Brolucizumab, and Ranibizumab in a Retinal Vascular Hyperpermeability Model

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William Schubert; Carsten Terjung; Ashique Rafique; Carmelo Romano; Philipp Ellinger; Kay D. Rittenhouse
TAGS: aflibercept, brolucizumab, oryctolagus cuniculus, ranibizumab, vascular endothelial growth factor a, anti-vascular endothelial growth factor therapy, calcium
Trans. Vis. Sci. Tech.. 2022; 11(10):36. https://doi.org/10.1167/tvst.11.10.36

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Neuroprotection of retinal ganglion cells using two vector approach for expression of TrkB receptor and agonist ligand

Henry Chen; Adrianna Latuszek; Ying Hu; Brijeshkumar Patel; Gaurang Patel; Jingtai Cao; Carl Romano

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):972 – F0369.

ARVO Annual Meeting Abstract June 2022

Ciliary Neurotrophic Factor protects retinal pigment epithelium and photoreceptor cells in sodium iodate induced retinal degeneration model

rajeevalochan wudali; Ying Hu; Carl Romano

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1770 – F0319.

ARVO Annual Meeting Abstract June 2022

ANGPTL7: A PROMISING TARGET FOR GLAUCOMA THERAPEUTICS

Carl Romano; Kavita Praveen; Sabrina Walley; Brijeshkumar Patel; Sarthak R Zaveri; Ming Yuan; Hua Yang; Jeremy Rabinowitz; Stephanie Lefebvre; Sarah Hyde; Scott Waldron; James Mcninch; Ying Hu; Giovanni Coppola; Vasant Jadhav; Gaurang Patel

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2850 – A0373.

ARVO Annual Meeting Abstract June 2022

RNAi BASED APPROACH FOR MYOC-ASSOCIATED GLAUCOMA

Gaurang Patel; Brijeshkumar Patel; Charleen Hunt; Sarthak R Zaveri; Sabrina Walley; rajeevalochan wudali; Sven-Moller Tank; James Mcninch; Mark Schlegel; Adam Castoreno; Elena Castellanos-Rizaldos; Abigail Liebow; Kavita Praveen; Ying Hu; Vasant Jadhav; Carl Romano

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3092.

ARVO Annual Meeting Abstract June 2022

Differential expression of complement genes in mammalian eyes

Hua Yang; Ming Yuan; Patel Gaurang; Aixu Sun; Adrianna Latuszek; Ying Hu; Jingtai Cao; Carl Romano

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4594 – F0386.

ARVO Annual Meeting Abstract June 2022

Retinoschisin deficiency induces persistent aberrant waves of activity affecting neuroglial signaling in the developing retina

Cyril Eleftheriou; Carlo Corona; Shireen Khattak; Elena Ivanova; Paola Bianchimano; Yang Liu; Duo Sun; Rupesh Singh; Julia Batoki; J Jason McAnany; Neal S Peachey; Carl Romano; Botir Sagdullaev

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2655.

Genetics November 2021

ERAP1, ERAP2, and Two Copies of HLA-Aw19 Alleles Increase the Risk for Birdshot Chorioretinopathy in HLA-A29 Carriers

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Sahar Gelfman; Dominique Monnet; Ann J. Ligocki; Thierry Tabary; Arden Moscati; Xiaodong Bai; Jan Freudenberg; Blerta Cooper; Jack A. Kosmicki; Sarah Wolf; Manuel A. R. Ferreira; John Overton; Jonathan Weyne; Eli A. Stahl; Aris Baras; Carmelo Romano; Jacques H. M. Cohen; Giovanni Coppola; Antoine Brézin; for the Regeneron Genetics Center
TAGS: alleles, human leukocyte antigens, vitiliginous chorioretinitis
Invest. Ophthalmol. Vis. Sci.. 2021; 62(14):3. https://doi.org/10.1167/iovs.62.14.3

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

A novel method to rapidly expand and perform single cell sequencing on T cells from vitreous biopsies

Raquel Deering; Wen Fury; Sunil K. Srivastava; Se Jeong; Sumit Sharma; Kimberly Baynes; Ashley Lowe; Michael Ramos; Evangelia Malahias; Christina Adler; Min Ni; Yi Wei; Mickey Atwal; Carmelo Romano; Gavin Thurston; jonathan weyne

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3463.

ARVO Annual Meeting Abstract June 2021

Intravitreal administration, but not systemic administration, of VEGF Mini-Trap effectively inhibits neovascularization in the Oxygen Induced Retinopathy (OIR) in mice

Eunice Cheung; Jingtai Cao; Carmelo Romano

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3293.

ARVO Annual Meeting Abstract June 2021

An Aflibercept-derived Mini-VEGF-Trap as a Potential Next-Generation VEGF Inhibitor

Raymond Wilson Leidich; Krunal Patel; Ashique Rafique; Annabel Romero Hernandez; Matthew Franklin; Miguel Lazo; Aynur Hermann; Gitanjali Sharma; Yiming Zhao; Hunter Chen; Nina Liu; Michael Rosconi; Carmelo Romano; William Olson; Neil Stahl

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):204.

ARVO Annual Meeting Abstract June 2021

An AAV vector carrying a chimeric photopigment for evaluating gene therapy methods in Old World primates

Rachel Barborek; Jessica Rowlan; James Kuchenbecker; Dragos Rezeanu; Marcus Mazzaferri; Briyana Bembry; Jose Rojas; Yajun Tang; Carmelo Romano; Jay Neitz; Maureen Neitz

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2785.

ARVO Annual Meeting Abstract June 2021

Identification and spatial distribution of novel molecular features of adult human corneal cell subtypes

Guillermo Lehmann; Ann J Ligocki; Wen Fury; Christian Gutierrez; Christina Adler; Tao Yang; Min Ni; Yu Bai; Yi Wei; Carmelo Romano

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):687.

ARVO Annual Meeting Abstract June 2021

Suprachoroidal space injection of AAV provides widespread gene expression in the mouse eye.

Shireen Khattak; Matthew-Mina Reyad; Duo Sun; Yang Liu; Carmelo Romano

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1193.

ARVO Annual Meeting Abstract June 2020

Cas9 and AAV Vector-Based Strategies for X-linked Juvenile Retinoschisis (XLRS) Therapy

Yang Liu; Charleen Hunt; Duo Sun; Shireen Khattak; Timothy Hanna; Clarissa Herman; Lynn Lee; Katie Huling; Tara Liao; Jingtai Cao; Guochun Gong; Carl Romano

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):800.

ARVO Annual Meeting Abstract June 2020

Disrupted spontaneous calcium signals in the glia and neurons in the developing retinoschisin-deficient retina

Cyril Eleftheriou; Carlo Corona; Paola Bianchimano; Elena Ivanova; Yang Lin; Duo Sun; Jingtai Cao; Carl Romano; Botir T Sagdullaev

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1060.

ARVO Annual Meeting Abstract June 2020

Potassium Voltage-gated channel, Isk-related family 3 (Kcne3) is a novel tip cell marker that plays a role in normal retinal vascular development and revascularization in the Oxygen Induced Retinopathy (OIR) model in mice.

Eunice Cheung; Jingtai Cao; Carl Romano

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2231.

ARVO Annual Meeting Abstract June 2020

Single cell-based analysis of human trabecular meshwork tissue provides a comprehensive cellular and molecular classification, identifying cell-type and region-specific expression of genes

Gaurang Patel; Wen Fury; Hua Yang; Ying Hu; Daniel Stamer; Carl Romano

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2329.

ARVO Annual Meeting Abstract June 2020

Ocular distribution of AAV variants after intravitreal and intracameral injections in mouse

Adrianna Latuszek; Hua Yang; Ming Yuan; Henry Chen; Brijeshkumar Patel; Gaurang Patel; Ying Hu; Jingtai Cao; Carl Romano

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2467.

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Intravitreal (IVT) CITED2 peptide attenuates early stages not late stages of Neovascularization in the Oxygen Induced Retinopathy (OIR) in Mice.

Evaluation of Molecular Properties versus In Vivo Performance of Aflibercept, Brolucizumab, and Ranibizumab in a Retinal Vascular Hyperpermeability Model

Neuroprotection of retinal ganglion cells using two vector approach for expression of TrkB receptor and agonist ligand

Ciliary Neurotrophic Factor protects retinal pigment epithelium and photoreceptor cells in sodium iodate induced retinal degeneration model

ANGPTL7: A PROMISING TARGET FOR GLAUCOMA THERAPEUTICS

RNAi BASED APPROACH FOR MYOC-ASSOCIATED GLAUCOMA

Differential expression of complement genes in mammalian eyes

Retinoschisin deficiency induces persistent aberrant waves of activity affecting neuroglial signaling in the developing retina

ERAP1, ERAP2, and Two Copies of HLA-Aw19 Alleles Increase the Risk for Birdshot Chorioretinopathy in HLA-A29 Carriers

A novel method to rapidly expand and perform single cell sequencing on T cells from vitreous biopsies

Intravitreal administration, but not systemic administration, of VEGF Mini-Trap effectively inhibits neovascularization in the Oxygen Induced Retinopathy (OIR) in mice

An Aflibercept-derived Mini-VEGF-Trap as a Potential Next-Generation VEGF Inhibitor

An AAV vector carrying a chimeric photopigment for evaluating gene therapy methods in Old World primates

Identification and spatial distribution of novel molecular features of adult human corneal cell subtypes

Suprachoroidal space injection of AAV provides widespread gene expression in the mouse eye.

Cas9 and AAV Vector-Based Strategies for X-linked Juvenile Retinoschisis (XLRS) Therapy

Disrupted spontaneous calcium signals in the glia and neurons in the developing retinoschisin-deficient retina

Potassium Voltage-gated channel, Isk-related family 3 (Kcne3) is a novel tip cell marker that plays a role in normal retinal vascular development and revascularization in the Oxygen Induced Retinopathy (OIR) model in mice.

Single cell-based analysis of human trabecular meshwork tissue provides a comprehensive cellular and molecular classification, identifying cell-type and region-specific expression of genes

Ocular distribution of AAV variants after intravitreal and intracameral injections in mouse

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