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ARVO Annual Meeting Abstract June 2022

Classification and growth rate of retinal atrophy after voretigene neparvovec-rzyl for RPE65-mediated retinal dystrophy

Nikhil Bommakanti; Benjamin Young; Robert Sisk; Audina M. Berrocal; Jacque L Duncan; Benjamin Bakall; Marc Mathias; Aaron Nagiel; Cagri G Besirli

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):456. doi:

ARVO Annual Meeting Abstract June 2022

Flow cytometry methods to detect markers of outer retinal stress and cell death in a model of acute nutrient stress

Shubha Subramaya; Roshini Fernando; Moloy Goswami; Eric Weh; HEATHER HAGER; Cagri G Besirli; Thomas J Wubben

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):792 – F0351. doi:

ARVO Annual Meeting Abstract June 2022

Novel PKM2 activators for photoreceptor neuroprotection: identifying potential clinical candidates

Sraboni Chaudhury; JASON RECH; BRENNAN WATCH; Eric Weh; HEATHER HAGER; Thomas J Wubben; Cagri G Besirli

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):670 – F0124. doi:

ARVO Annual Meeting Abstract June 2022

Small molecule PKM2 activators in the treatment of rd10 photoreceptor degeneration

Warren Pan; Eric Weh; Roshini Fernando; Sraboni Chaudhury; Cagri G Besirli; Thomas J Wubben

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1779 – F0328. doi:

ARVO Annual Meeting Abstract June 2022

Promoting PKM2 tetramerization to treat RPE epithelial-to-mesenchymal transition in proliferative vitreoretinopathy

Vikram Sharma; Moloy Goswami; Qitao Zhang; Sraboni Chaudhury; Katie Li; Hima Bindu Durumulta; Anthony Andren; Costas A Lyssiotis; Cagri G Besirli; Jason Matthew Lewis Miller; Thomas J Wubben

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3051 – F0422. doi:

ARVO Annual Meeting Abstract June 2022

Trends in retinopathy of prematurity training and future practice intentions among retina and pediatric ophthalmology fellows

Emily Eton; Benjamin Young; Cagri G Besirli

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4173 – F0233. doi:

ARVO Annual Meeting Abstract June 2021

Perifoveal Chorioretinal Atrophy Following Subretinal Injection of Voretigene Neparvovec-rzyl for RPE65-mediated Leber Congenital Amaurosis

William S Gange; Robert A Sisk; Cagri G Besirli; Thomas C Lee; Mark Borchert; Jesse Sengillo; Carlos Mendoza; Audina M Berrocal; Aaron Nagiel

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3292. doi:

ARVO Annual Meeting Abstract June 2021

Modulation of pyruvate kinase M2 activity as a therapy in a primary RPE cell culture model of proliferative vitreoretinopathy

Katie Xiaoou Li; Moloy T. Goswami; Qitao Zhang; Hima Bindu Durumutla; Sraboni Chaudhury; Cagri G Besirli; Jason Miller; Thomas J Wubben

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2213. doi:

ARVO Annual Meeting Abstract June 2021

HK2 and PKM2 deletion leads to outer segment shortening and photoreceptor degeneration

Eric Weh; Katie Xiaoou Li; Heather Hager; Sarah Sheskey; Thomas J Wubben; Cagri G Besirli

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2985. doi:

ARVO Annual Meeting Abstract June 2021

Quantitative Analysis of VEGF in Infant Tears as a Biomarker for ROP

Omar Moinuddin; Jessie Magnani; Sanjana Sathrasala; Mercy Pawar; Rebecca Vartanian; Cagri G Besirli

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3257. doi:

ARVO Annual Meeting Abstract June 2021

Glutaminase deficiency disrupts the bioenergetic and antioxidant fidelity of photoreceptors to induce rapid degeneration

Moloy Goswami; Eric Weh; Hima Bindu Durmutla; Heather Hager; Sraboni Chaudhury; costas lyssiotis; Cagri G Besirli; Thomas J Wubben

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3075. doi:

ARVO Annual Meeting Abstract June 2020

Association of metformin and development of dry age-related macular degeneration in a U.S. insurance claims database

Emily Ann Eton; Thomas J Wubben; Cagri G Besirli; Peiying Hua; Brendan McGeehan; Brian L VanderBeek

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2993. doi:

ARVO Annual Meeting Abstract June 2020

Development of novel pyruvate kinase muscle isoform 2 (PKM2) activators for photoreceptor neuroprotection

Thomas J Wubben; Jason C Rech; Mercy D Pawar; Eric Weh; Cagri G Besirli

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4938. doi:

Review June 2020

Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium

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Debra A. Thompson; Alessandro Iannaccone; Robin R. Ali; Vadim Y. Arshavsky; Isabelle Audo; James W. B. Bainbridge; Cagri G. Besirli; David G. Birch; Kari E. Branham; Artur V. Cideciyan; Steven P. Daiger; Deniz Dalkara; Jacque L. Duncan; Abigail T. Fahim; John G. Flannery; Roberto Gattegna; John R. Heckenlively; Elise Heon; K. Thiran Jayasundera; Naheed W. Khan; Henry Klassen; Bart P. Leroy; Robert S. Molday; David C. Musch; Mark E. Pennesi; Simon M. Petersen-Jones; Eric A. Pierce; Rajesh C. Rao; Thomas A. Reh; Jose A. Sahel; Dror Sharon; Paul A. Sieving; Enrica Strettoi; Paul Yang; David N. Zacks; The Monaciano Consortium
TAGS: outcome measures, retinal diseases, surrogate endpoints, genetics, vision, natural history, ethics, gene therapy
Trans. Vis. Sci. Tech.. 2020; 9(7):2. doi: https://doi.org/10.1167/tvst.9.7.2

Articles September 2019

Magnetic Hyperthermia in Y79 Retinoblastoma and ARPE-19 Retinal Epithelial Cells: Tumor Selective Apoptotic Activity of Iron Oxide Nanoparticle

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Hakan Demirci; Naziha Slimani; Mercy Pawar; Ronald E. Kumon; Prem Vaishnava; Cagri G. Besirli
TAGS: ferumoxytol, hyperthermia, nanoparticles, neoplasms, retinoblastoma, epithelial cells
Trans. Vis. Sci. Tech.. 2019; 8(5):18. doi: https://doi.org/10.1167/tvst.8.5.18

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Survey of Intravitreal Injection Practice Patterns among Retina Specialists

Stephen J Smith; Therese Sassalos; Nish Patel; Chris Andrews; David C Musch; Cagri G Besirli

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):109. doi:

ARVO Annual Meeting Abstract July 2019

Protective role of mesencephalic astrocyte-derived neurotrophic factor (MANF) in photoreceptor death

Mercy D Pawar; Taichi Suzuki; Kevin Toolan; Cagri G Besirli

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6606. doi:

ARVO Annual Meeting Abstract July 2019

Photoreceptor Metabolic Reprogramming in an In-Vivo Model of NaIO3 Induced Retinal Degeneration

Omar Moinuddin; Eric Weh; Zuzanna Lutrzykowska; Cagri G Besirli

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1679. doi:

ARVO Annual Meeting Abstract July 2019

The neuroprotective role of Hexokinase 2 in photoreceptor survival

Eric Weh; Zuzanna Lutrzykowska; Mercy D Pawar; Heather Hager; Cagri G Besirli

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1721. doi:

ARVO Annual Meeting Abstract July 2019

Potential cancer therapy for activation of metabolic enzyme pyruvate kinase muscle isozyme 2, PKM2, provides photoreceptor neuroprotection

Thomas Wubben; Mercy D Pawar; Eric Weh; Zuzanna Lutrzykowska; Andrew Smith; Cagri G Besirli

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5178. doi:

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Classification and growth rate of retinal atrophy after voretigene neparvovec-rzyl for RPE65-mediated retinal dystrophy

Flow cytometry methods to detect markers of outer retinal stress and cell death in a model of acute nutrient stress

Novel PKM2 activators for photoreceptor neuroprotection: identifying potential clinical candidates

Small molecule PKM2 activators in the treatment of rd10 photoreceptor degeneration

Promoting PKM2 tetramerization to treat RPE epithelial-to-mesenchymal transition in proliferative vitreoretinopathy

Trends in retinopathy of prematurity training and future practice intentions among retina and pediatric ophthalmology fellows

Perifoveal Chorioretinal Atrophy Following Subretinal Injection of Voretigene Neparvovec-rzyl for RPE65-mediated Leber Congenital Amaurosis

Modulation of pyruvate kinase M2 activity as a therapy in a primary RPE cell culture model of proliferative vitreoretinopathy

HK2 and PKM2 deletion leads to outer segment shortening and photoreceptor degeneration

Quantitative Analysis of VEGF in Infant Tears as a Biomarker for ROP

Glutaminase deficiency disrupts the bioenergetic and antioxidant fidelity of photoreceptors to induce rapid degeneration

Association of metformin and development of dry age-related macular degeneration in a U.S. insurance claims database

Development of novel pyruvate kinase muscle isoform 2 (PKM2) activators for photoreceptor neuroprotection

Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium

Magnetic Hyperthermia in Y79 Retinoblastoma and ARPE-19 Retinal Epithelial Cells: Tumor Selective Apoptotic Activity of Iron Oxide Nanoparticle

Survey of Intravitreal Injection Practice Patterns among Retina Specialists

Protective role of mesencephalic astrocyte-derived neurotrophic factor (MANF) in photoreceptor death

Photoreceptor Metabolic Reprogramming in an In-Vivo Model of NaIO3 Induced Retinal Degeneration

The neuroprotective role of Hexokinase 2 in photoreceptor survival

Potential cancer therapy for activation of metabolic enzyme pyruvate kinase muscle isozyme 2, PKM2, provides photoreceptor neuroprotection

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