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Retinal Cell Biology October 2022

Targeted Expression of Retinoschisin by Retinal Bipolar Cells in XLRS Promotes Resolution of Retinoschisis Cysts Sans RS1 From Photoreceptors

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Camasamudram Vijayasarathy; Yong Zeng; Dario Marangoni; Lijin Dong; Zhuo-Hua Pan; Elizabeth M. Simpson; Robert N. Fariss; Paul A. Sieving
TAGS: cysts, mice, photoreceptors, retina, retinal bipolar cells, retinoschisis, spatial vectors
Invest. Ophthalmol. Vis. Sci.. 2022; 63(11):8. doi: https://doi.org/10.1167/iovs.63.11.8

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Inhibition of Sodium Iodate-Induced Apoptosis in Human RPE by the Stearoyl Coenzyme A Desaturase Inhibitor Sterculic acid

William Samuel; Camasamudram Vijayasarathy; Sheetal Uppal; Todd Duncan; T. Michael Redmond

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3906 – A0108. doi:

Articles June 2020

Trans-Ocular Electric Current In Vivo Enhances AAV-Mediated Retinal Transduction in Large Animal Eye After Intravitreal Vector Administration

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Hongman Song; Yong Zeng; Sheik Pran Babu Sardar Pasha; Ronald A. Bush; Camasamudram Vijayasarathy; Haohua Qian; Lisa Wei; Henry E. Wiley; Zhijian Wu; Paul A. Sieving
TAGS: eye, retina, spatial vectors, transfer technique, oryctolagus cuniculus, mice, fibroblast growth factor 2, intravitreal injections
Trans. Vis. Sci. Tech.. 2020; 9(7):28. doi: https://doi.org/10.1167/tvst.9.7.28

Retina March 2017

Rearing Light Intensity Affects Inner Retinal Pathology in a Mouse Model of X-Linked Retinoschisis but Does Not Alter Gene Therapy Outcome

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Dario Marangoni; Zeng Yong; Sten Kjellström; Camasamudram Vijayasarathy; Paul A. Sieving; Ronald A. Bush
TAGS: gene therapy, light intensity, mice, x-linked retinoschisis, electroretinography, pathology
Invest. Ophthalmol. Vis. Sci.. 2017; 58(3):1656-1664. doi: https://doi.org/10.1167/iovs.16-21016

Articles July 2016

Retinal Structure and Gene Therapy Outcome in Retinoschisin-Deficient Mice Assessed by Spectral-Domain Optical Coherence Tomography

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Yong Zeng; Ronald S. Petralia; Camasamudram Vijayasarathy; Zhijian Wu; Suja Hiriyanna; Hongman Song; Ya-Xian Wang; Paul A. Sieving; Ronald A. Bush
TAGS: gene therapy, mice, retina, diagnostic imaging, mice, knockout
Invest. Ophthalmol. Vis. Sci.. 2016; 57(9):OCT277-OCT287. doi: https://doi.org/10.1167/iovs.15-18920

Includes: Supplemental Content

Retinal Cell Biology May 2016

NADPH Oxidase Contributes to Photoreceptor Degeneration in Constitutively Active RAC1 Mice

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Hongman Song; Camasamudram Vijayasarathy; Yong Zeng; Dario Marangoni; Ronald A. Bush; Zhijian Wu; Paul A. Sieving
TAGS: mice, nadph oxidases, photoreceptors, retina, rod photoreceptors, superoxides, tissue degeneration, injections, proteins, oxidative stress
Invest. Ophthalmol. Vis. Sci.. 2016; 57(6):2864-2875. doi: https://doi.org/10.1167/iovs.15-18974

Retina October 2015

Intravitreal Ciliary Neurotrophic Factor Transiently Improves Cone-Mediated Function in a CNGB3 −/− Mouse Model of Achromatopsia

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Dario Marangoni; Camasamudram Vijayasarathy; Ronald A. Bush; Lisa L. Wei; Rong Wen; Paul A. Sieving
TAGS: ciliary neurotrophic factor, mice, retinal cone, electroretinography, achromatopsia
Invest. Ophthalmol. Vis. Sci.. 2015; 56(11):6810-6822. doi: https://doi.org/10.1167/iovs.15-16866

ARVO Annual Meeting Abstract June 2015

Proinflammatory Cytokines Induce Epithelial-Mesenchymal Transition in Retinal Pigment Epithelial Cells

R Krishnan Kutty; William Samuel; Chandrasekharam N Nagineni; Cynthia Jaworski; Todd Duncan; Camasamudram Vijayasarathy; T Michael Redmond

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4222. doi:

ARVO Annual Meeting Abstract June 2015

Intravitreal CNTF transiently improves residual cone function in CNGB3 −/− mouse

Dario Marangoni; Camasamudram Vijayasarathy; Ronald A Bush; Lisa Wei; Rong Wen; Paul A Sieving

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):479. doi:

ARVO Annual Meeting Abstract June 2015

Constitutively Active RAC1 Causes Photoreceptor Degeneration through NADPH Oxidase-Mediated Oxidative Stress

Hongman Song; Ronald A Bush; Yong Zeng; Camasamudram Vijayasarathy; Dario Marangoni; Paul A Sieving

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5451. doi:

Retinal Cell Biology April 2014

Transgenic Expression of Constitutively Active RAC1 Disrupts Mouse Rod Morphogenesis

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Hongman Song; Ronald A. Bush; Camasamudram Vijayasarathy; Robert N. Fariss; Sten Kjellstrom; Paul A. Sieving
TAGS: animals, transgenic, mice, morphogenesis, photoreceptors, retina, rod photoreceptors, rhodopsin, polarity, proteins, antibodies
Invest. Ophthalmol. Vis. Sci.. 2014; 55(4):2659-2668. doi: https://doi.org/10.1167/iovs.13-13649

ARVO Annual Meeting Abstract June 2013

Resveratrol Protects Human Retinal Pigment Epithelial Cells from Inflammatory Insults

R Kutty; Chandra Nagineni; William Samuel; Todd Duncan; Camasamudram Vijayasarathy; Cynthia Jaworski; T. Michael Redmond

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):4989. doi:

ARVO Annual Meeting Abstract April 2011

Rs1 Knockout Mice Show Altered Transducin Translocation But Not Arrestin In Response To Light At Early Age

Lucia Ziccardi; Camasamudram Vijayasarathy; Robert N. Fariss; Maria M. Campos; Ronald A. Bush; Paul A. Sieving

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2667. doi:

Retina November 2009

Null Retinoschisin-Protein Expression from an RS1 c354del1-ins18 Mutation Causing Progressive and Severe XLRS in a Cross-Sectional Family Study

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Camasamudram Vijayasarathy; Lucia Ziccardi; Yong Zeng; Nizar Smaoui; Rafael C. Caruso; Paul A. Sieving
TAGS: electroretinography, family studies, mutation, proteins, exons, reverse transcriptase polymerase chain reaction
Invest. Ophthalmol. Vis. Sci.. 2009; 50(11):5375-5383. doi: https://doi.org/10.1167/iovs.09-3839

Retinal Cell Biology August 2008

Synaptic Pathology in Retinoschisis Knockout ( Rs1 −/ y ) Mouse Retina and Modification by rAAV- Rs1 Gene Delivery

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Yuichiro Takada; Camasamudram Vijayasarathy; Yong Zeng; Sten Kjellstrom; Ronald A. Bush; Paul A. Sieving
TAGS: genes, mice, retina, retinoschisis, proteins, photoreceptors, electroretinography, postsynaptic density protein-95, pathology
Invest. Ophthalmol. Vis. Sci.. 2008; 49(8):3677-3686. doi: https://doi.org/10.1167/iovs.07-1071

Biochemistry and Molecular Biology March 2007

Retinoschisin Is a Peripheral Membrane Protein with Affinity for Anionic Phospholipids and Affected by Divalent Cations

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Camasamudram Vijayasarathy; Yuichiro Takada; Yong Zeng; Ronald A. Bush; Paul A. Sieving
TAGS: divalent cations, membrane proteins, phospholipids, proteins, tissue membrane, lipids, affinity, photoreceptors, cell membrane
Invest. Ophthalmol. Vis. Sci.. 2007; 48(3):991-1000. doi: https://doi.org/10.1167/iovs.06-0915

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Targeted Expression of Retinoschisin by Retinal Bipolar Cells in XLRS Promotes Resolution of Retinoschisis Cysts Sans RS1 From Photoreceptors

Inhibition of Sodium Iodate-Induced Apoptosis in Human RPE by the Stearoyl Coenzyme A Desaturase Inhibitor Sterculic acid

Trans-Ocular Electric Current In Vivo Enhances AAV-Mediated Retinal Transduction in Large Animal Eye After Intravitreal Vector Administration

Rearing Light Intensity Affects Inner Retinal Pathology in a Mouse Model of X-Linked Retinoschisis but Does Not Alter Gene Therapy Outcome

Retinal Structure and Gene Therapy Outcome in Retinoschisin-Deficient Mice Assessed by Spectral-Domain Optical Coherence Tomography

NADPH Oxidase Contributes to Photoreceptor Degeneration in Constitutively Active RAC1 Mice

Intravitreal Ciliary Neurotrophic Factor Transiently Improves Cone-Mediated Function in a CNGB3 −/− Mouse Model of Achromatopsia

Proinflammatory Cytokines Induce Epithelial-Mesenchymal Transition in Retinal Pigment Epithelial Cells

Intravitreal CNTF transiently improves residual cone function in CNGB3 −/− mouse

Constitutively Active RAC1 Causes Photoreceptor Degeneration through NADPH Oxidase-Mediated Oxidative Stress

Transgenic Expression of Constitutively Active RAC1 Disrupts Mouse Rod Morphogenesis

Resveratrol Protects Human Retinal Pigment Epithelial Cells from Inflammatory Insults

Rs1 Knockout Mice Show Altered Transducin Translocation But Not Arrestin In Response To Light At Early Age

Null Retinoschisin-Protein Expression from an RS1 c354del1-ins18 Mutation Causing Progressive and Severe XLRS in a Cross-Sectional Family Study

Synaptic Pathology in Retinoschisis Knockout ( Rs1 −/ y ) Mouse Retina and Modification by rAAV- Rs1 Gene Delivery

Retinoschisin Is a Peripheral Membrane Protein with Affinity for Anionic Phospholipids and Affected by Divalent Cations

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