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Immunology and Microbiology February 2025

Elevated Plasma Complement Factors in CRB1 -Associated Inherited Retinal Dystrophies

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Lude Moekotte; Joke H. de Boer; Sanne Hiddingh; Aafke de Ligt; Xuan-Thanh-An Nguyen; Carel B. Hoyng; Chris F. Inglehearn; Martin McKibbin; Tina M. Lamey; Jennifer A. Thompson; Fred K. Chen; Terri L. McLaren; Alaa AlTalbishi; Daan M. Panneman; Erica G. M. Boonen; Sandro Banfi; Béatrice Bocquet; Isabelle Meunier; Elfride De Baere; Robert Koenekoop; Monika Ołdak; Carlo Rivolta; Lisa Roberts; Raj Ramesar; Rasa Strupaitė-Šileikienė; Susanne Kohl; G. Jane Farrar; Marion van Vugt; Jessica van Setten; Susanne Roosing; L. Ingeborgh van den Born; Camiel J. F. Boon; Maria M. van Genderen; Jonas J. W. Kuiper
TAGS: complement system proteins, hereditary retinal dystrophy, plasma, proteins, genotype, proteome, genes
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):55. https://doi.org/10.1167/iovs.66.2.55

Includes: Supplemental Content

Artificial Intelligence September 2024

Generalizable Deep Learning for the Detection of Incomplete and Complete Retinal Pigment Epithelium and Outer Retinal Atrophy: A MACUSTAR Report

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Coen de Vente; Philippe Valmaggia; Carel B. Hoyng; Frank G. Holz; Mohammad M. Islam; Caroline C. W. Klaver; Camiel J. F. Boon; Steffen Schmitz-Valckenberg; Adnan Tufail; Marlene Saßmannshausen; Clara I. Sánchez; on behalf of the MACUSTAR Consortium
TAGS: datasets, deep learning, eye, retinal atrophy, retinal pigment epithelium, biological markers, cohort studies, training
Trans. Vis. Sci. Tech.. 2024; 13(9):11. https://doi.org/10.1167/tvst.13.9.11

Includes: Supplemental Content

Genetics August 2024

Frequency and Genetic Spectrum of Inherited Retinal Dystrophies in a Large Dutch Pediatric Cohort: The RD5000 Consortium

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Pam A. T. Heutinck; L. Ingeborgh van den Born; Maikel Vermeer; Adriana I. Iglesias Gonzales; Carel B. Hoyng; Jan Willem R. Pott; Hester Y. Kroes; Mary J. van Schooneveld; Camiel J. F. Boon; Maria M. van Genderen; Astrid S. Plomp; Yvonne de Jong-Hesse; Michelle B. van Egmond-Ebbeling; Lies H. Hoefsloot; Arthur A. Bergen; Caroline C. W. Klaver; Magda A. Meester-Smoor; Alberta A. H. J. Thiadens; Virginie J. M. Verhoeven
TAGS: child, cohort studies, dutch, genetics, hereditary retinal dystrophy, pediatrics, phenotype, genes
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):40. https://doi.org/10.1167/iovs.65.10.40

Includes: Supplemental Content

Retina July 2024

Differential Expression of Sex-Steroid Receptors in the Choroid Aligns With Central Serous Chorioretinopathy Sex Prevalence Across Different Ages

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Sekar Galuh; Onno C. Meijer; Joost Brinks; Reinier O. Schlingemann; Camiel J. F. Boon; Robert M. Verdijk; Elon H. C. van Dijk
TAGS: central serous chorioretinopathy, choroid, gonadal steroid hormones, prevalence, electroconvulsive therapy, epidural cortical stimulation, stromal cells, premenopause
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):5. https://doi.org/10.1167/iovs.65.8.5

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Choroidal hyperpermeability patterns correlate with disease severity in central serous chorioretinopathy: CERTAIN study report 2.

Laurenz J. B. Pauleikhoff; Roselie M. H. Diederen; Jennifer M. Chang-Wolf; Annette C. Moll; Reinier O. Schlingemann; Elon H. C. van Dijk; Camiel J. F. Boon

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1727.

ARVO Annual Meeting Abstract June 2024

Test-retest variability of mean sensitivity and volume sensitivity on microperimetry in patients with retinitis pigmentosa

Jessica Serena Karuntu; Xuan-Thanh-An Nguyen; Jasleen K Jolly; Camiel J. F. Boon

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3093.

ARVO Annual Meeting Abstract June 2024

Genome-wide association study meta-analysis in CSCR points to genes important in vascular tissue

Elizabeth J Rossin; Joel Rämö; Bryan Gorman; Elon Van Dijk; Wen-Chih Wu; Suzanne Yzer; Neal S Peachey; Joni Tururen; Camiel J. F. Boon; Patrick Ellinor; Mark Daly; Sudha K Iyengar

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3119.

Retina May 2024

Retinal Dystrophies Associated With Peripherin-2: Genetic Spectrum and Novel Clinical Observations in 241 Patients

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Rachael C. Heath Jeffery; Jennifer A. Thompson; Johnny Lo; Enid S. Chelva; Sean Armstrong; Jose S. Pulido; Rebecca Procopio; Andrea L. Vincent; Lorenzo Bianco; Maurizio Battaglia Parodi; Lucia Ziccardi; Giulio Antonelli; Lucilla Barbano; João P. Marques; Sara Geada; Ana L. Carvalho; Wei C. Tang; Choi M. Chan; Camiel J. F. Boon; Jonathan Hensman; Ta-Ching Chen; Chien-Yu Lin; Pei-Lung Chen; Ajoy Vincent; Anupreet Tumber; Elise Heon; John R. Grigg; Robyn V. Jamieson; Elisa E. Cornish; Benjamin M. Nash; Shyamanga Borooah; Lauren N. Ayton; Alexis Ceecee Britten-Jones; Thomas L. Edwards; Jonathan B. Ruddle; Abhishek Sharma; Rowan G. Porter; Tina M. Lamey; Terri L. McLaren; Samuel McLenachan; Danial Roshandel; Fred K. Chen
TAGS: genetics, phenotype, retinal dystrophies, fundus autofluorescence imaging, electroretinography
Invest. Ophthalmol. Vis. Sci.. 2024; 65(5):22. https://doi.org/10.1167/iovs.65.5.22

Includes: Supplemental Content

Immunology and Microbiology October 2023

CRB1 -Associated Retinal Dystrophy Patients Have Expanded Lewis Glycoantigen-Positive T Cells

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Lude Moekotte; Jonas J. W. Kuiper; Sanne Hiddingh; Xuan-Thanh-An Nguyen; Camiel J. F. Boon; L. Ingeborgh van den Born; Joke H. de Boer; Maria M. van Genderen
TAGS: retinal dystrophies, t-lymphocytes, flow cytometry
Invest. Ophthalmol. Vis. Sci.. 2023; 64(13):6. https://doi.org/10.1167/iovs.64.13.6

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Risk variants in the CFH gene associate with elevated levels of coagulation and complement factors in idiopathic multifocal choroiditis

Evianne Laura de Groot; Jeannette Ossewaarde-van Norel; Joke H. de Boer; Sanne Hiddingh; Bjorn Bakker; Ramon A.C. van Huet; Ninette H. ten Dam-van Loon; Alberta A H J Thiadens; Magda A. Meester; Yvonne de Jong-Hesse; Leonoor I. Los; Anneke I. den Hollander; Camiel J F Boon; Kristel R. van Eijk; Carel C B Hoyng; Jonas J.W. Kuiper

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4528.

ARVO Annual Meeting Abstract June 2023

Risk factors for developing subretinal fluid in the fellow eye in chronic central serous chorioretinopathy patients

Helena Margaret Anthonia Feenstra; Tahir Çakar; Camiel J F Boon; Elon Van Dijk

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5405.

ARVO Annual Meeting Abstract June 2023

CLINICAL, GENOTYPIC AND IMAGING CHARACTERISTICS OF DIFFERENT ABCA4 RETINOPATHIES

Francesca Lamanna; Francesco Romano; Alessandro Siligato; Camiel J F Boon; Aniruddha Agarwal; Gagan Kalra; Chiara Medori; Matteo Bertelli; Alessandro Invernizzi; Anna Paola Salvetti; Giovanni Staurenghi

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1532.

ARVO Annual Meeting Abstract June 2023

Efficacy of carbonic anhydrase inhibitors on cystoid macular lesions and visual acuity in patients with X-linked retinoschisis

Jonathan Hensman; Leo Hahn; Rosalie Diederen; Jacoline ten Brink; Ralph Florijn; Arthur Bergen; Ine Strubbe; Pam Heutinck; Maria M van Genderen; Ingeborgh Van Den Born; Alberta A H J Thiadens; Carel C B Hoyng; Bart Peter Leroy; Camiel J F Boon

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1550.

ARVO Annual Meeting Abstract June 2023

Features of venous overload in central serous chorioretinopathy

Laurenz J. B. Pauleikhoff; Rosalie Diederen; Elon Van Dijk; Camiel J F Boon

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3656.

Retina February 2023

Repeatability of Quantitative Autofluorescence Imaging in a Multicenter Study Involving Patients With Recessive Stargardt Disease 1

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Patty P.A. Dhooge; Philipp T. Möller; Nils Meland; Katarina Stingl; Camiel J. F. Boon; Andrew J. Lotery; Maurizio Battaglia Parodi; Philipp Herrmann; Wolfgang Klein; Mario G. Fsadni; Thomas H. Wheeler-Schilling; Frank G. Holz; Carel B. Hoyng; Steffen Schmitz-Valckenberg; for the Soraprazan Consortium
TAGS: autofluorescence, diagnostic imaging, multicenter studies, stargardt's disease, reading (activity), eye
Trans. Vis. Sci. Tech.. 2023; 12(2):1. https://doi.org/10.1167/tvst.12.2.1

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

A comparison of human stem cell-retinal organoid protocols as a way to investigate the timing and regulation of RS1 protein

Andrea Heredero; Ellie L. Wagstaff; Anneloor L M A Ten Asbroek; Jacoline B ten Brink; Arthur A. Bergen; Camiel J F Boon

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2428 – F0372.

ARVO Annual Meeting Abstract June 2022

Safety and efficacy of fovea-involving half-dose photodynamic therapy for chronic central serous chorioretinopathy

Helena Margaret Anthonia Feenstra; Roselie M.H. Diederen; Martine J.C.M. Lamme; Sascha Fauser; Susan M. Downes; Reinier O. Schlingemann; Carel C B Hoyng; Elon H.C. van Dijk; Camiel J F Boon

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):37.

ARVO Annual Meeting Abstract June 2022

Sex Hormones in Males and Females with Active Central Serous Chorioretinopathy

Joost Brinks; Elon H.C. van Dijk; Roula Tsonaka; Onno C. Meijer; Camiel J F Boon

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1180 – A0034.

ARVO Annual Meeting Abstract June 2022

Clinical and histopathologic characteristics of autosomal dominant cone-rod dystrophy caused by mutations in the CRX gene

Isa van der Veen; Leo Hahn; Michalis Georgiou; Mary J. van Schooneveld; Jacoline B ten Brink; Ralph J. Florijn; Annette Ossewaarde-van Norel; Omar Abdul Rahman Mahroo; Emanuel de Carvalho; Arthur A. Bergen; Michel Michaelides; Camiel J F Boon

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1785 – F0334.

ARVO Annual Meeting Abstract June 2022

Generation of an in vitro stem cell based model for researching gyrate atrophy of the choroid and retina

Mark Buijs; Berith Balfoort; Anneloor L M A Ten Asbroek; Camiel J F Boon; Marion Brands; Riekelt Houtkooper; Margreet Wagenmakers; Hans Waterham; Corrie Timmer; Ronald Wanders; Clara Karnebeek; Arthur A. Bergen

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2430 – F0374.

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Elevated Plasma Complement Factors in CRB1 -Associated Inherited Retinal Dystrophies

Generalizable Deep Learning for the Detection of Incomplete and Complete Retinal Pigment Epithelium and Outer Retinal Atrophy: A MACUSTAR Report

Frequency and Genetic Spectrum of Inherited Retinal Dystrophies in a Large Dutch Pediatric Cohort: The RD5000 Consortium

Differential Expression of Sex-Steroid Receptors in the Choroid Aligns With Central Serous Chorioretinopathy Sex Prevalence Across Different Ages

Choroidal hyperpermeability patterns correlate with disease severity in central serous chorioretinopathy: CERTAIN study report 2.

Test-retest variability of mean sensitivity and volume sensitivity on microperimetry in patients with retinitis pigmentosa

Genome-wide association study meta-analysis in CSCR points to genes important in vascular tissue

Retinal Dystrophies Associated With Peripherin-2: Genetic Spectrum and Novel Clinical Observations in 241 Patients

CRB1 -Associated Retinal Dystrophy Patients Have Expanded Lewis Glycoantigen-Positive T Cells

Risk variants in the CFH gene associate with elevated levels of coagulation and complement factors in idiopathic multifocal choroiditis

Risk factors for developing subretinal fluid in the fellow eye in chronic central serous chorioretinopathy patients

CLINICAL, GENOTYPIC AND IMAGING CHARACTERISTICS OF DIFFERENT ABCA4 RETINOPATHIES

Efficacy of carbonic anhydrase inhibitors on cystoid macular lesions and visual acuity in patients with X-linked retinoschisis

Features of venous overload in central serous chorioretinopathy

Repeatability of Quantitative Autofluorescence Imaging in a Multicenter Study Involving Patients With Recessive Stargardt Disease 1

A comparison of human stem cell-retinal organoid protocols as a way to investigate the timing and regulation of RS1 protein

Safety and efficacy of fovea-involving half-dose photodynamic therapy for chronic central serous chorioretinopathy

Sex Hormones in Males and Females with Active Central Serous Chorioretinopathy

Clinical and histopathologic characteristics of autosomal dominant cone-rod dystrophy caused by mutations in the CRX gene

Generation of an in vitro stem cell based model for researching gyrate atrophy of the choroid and retina

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