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ARVO Annual Meeting Abstract June 2021

Common and rare genetic risk variants for Age-related Macular Degeneration progression in the Coimbra Eye Study.

Claudia Farinha; Patricia Barreto; Rita Coimbra; Maria Luz Cachulo; Joana Barbosa Melo; Isabel Marques Carreira; Maria Helena Madeira; Anneke I Den Hollander; Carel Hoyng; Jose G Cunha-Vaz; Rufino Silva

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1489. doi:

ARVO Annual Meeting Abstract June 2021

Clinical and genetic spectrum of patients with GUCY2D -associated retinal dystrophies

Leo Hahn; Mary J. van Schooneveld; Michalis Georgiou; Magda Meester-Smoor; Andrew J Lotery; Maria M. van Genderen; Jeannette Ossewaarde-van Norel; L. Ingeborgh van den Born; Carel Hoyng; Caroline C. W. Klaver; Susan M Downes; Martin McKibbin; Arthur A.B. Bergen; Bart Leroy; Michel Michaelides; Camiel Boon

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1544. doi:

ARVO Annual Meeting Abstract June 2021

X-linked retinoschisis: Long-term follow-up and genetic spectrum in 340 patients

Camiel J F Boon; Leo Hahn; Mary J. van Schooneveld; Ralph J. Florijn; Jacoline B. ten Brink; Ine Strubbe; Michel H. Hof; Magda Meester-Smoor; Caroline C. W. Klaver; Alberta A. Thiadens; Jeannette Ossewaarde-van Norel; L. Ingeborgh van den Born; Carel Hoyng; Maria M. van Genderen; Bart P Leroy; Arthur A.B. Bergen

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2172. doi:

ARVO Annual Meeting Abstract June 2021

Long-term follow-up of chronic central serous chorioretinopathy patients after primary treatment of oral eplerenone or half-dose photodynamic therapy and crossover treatment: SPECTRA trial report No. 3

Helena Feenstra; Thomas Jurian van Rijssen; Roselie Diederen; Carel Hoyng; Reinier Schlingemann; Elon van Dijk; Camiel J F Boon

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2170. doi:

ARVO Annual Meeting Abstract June 2021

Patient-reported visual functioning in persons with bi-allelic USH2A variants

Elise Heon; B. Michele Melia; Laura E Bocchino; Jacque L Duncan; Allison Ayala; Chris Bradley; Isabelle Audo; Janet K Cheetham; Gislin Dagnelie; Todd Durham; Carel Hoyng; Nieraj Jain; Thiran Jayasundera; Mark E Pennesi; Christina Y Weng

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3541. doi:

ARVO Annual Meeting Abstract June 2021

Supplement intake and plasma nutritional biomarkers reduce risk for second eye progression in age-related macular degeneration.

Yara T E Lechanteur; Thomas J Heesterbeek; Anneke I Den Hollander; Laura Lores de Motta; Ilhan E Acar; Eiko K de Jong; B. Jeroen Klevering; Caroline C. W. Klaver; Carel Hoyng

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):347. doi:

ARVO Annual Meeting Abstract June 2021

Genetic characterization of a Portuguese age-related macular degeneration population

Patrícia Barreto; Claudia Farinha; Rita Coimbra; Maria Luz Cachulo; Joana Barbosa Melo; Isabel Marques Carreira; Maria Helena Madeira; Carel Hoyng; Anneke I Den Hollander; Jose G Cunha-Vaz; Rufino Silva

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):310. doi:

ARVO Annual Meeting Abstract June 2021

Long-read technologies unravel hidden inversion-duplication in a family with choroideremia

Susanne Roosing; Zeinab Fadaie; Tuomo Mantere; Ronny Derks; Amber den Ouden; Michael Kwint; Luke O'Gorman; Dyon Valkenburg; Carel Hoyng; Christian Gilissen; Lisenka E.L.M. Vissers; Marcel Nelen; Frans P.M. Cremers; Kornelia Neveling; Alexander Hoischen

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1. doi:

Perspective April 2021

Tackling the Challenges of Product Development Through a Collaborative Rare Disease Network: The Foundation Fighting Blindness Consortium

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Todd A. Durham; Jacque L. Duncan; Allison R. Ayala; David G. Birch; Janet K. Cheetham; Frederick L. Ferris, III; Carel B. Hoyng; Mark E. Pennesi; José-Alain Sahel; for the Foundation Fighting Blindness Consortium Investigator Group
TAGS: blindness, rare diseases
Trans. Vis. Sci. Tech.. 2021; 10(4):23. doi: https://doi.org/10.1167/tvst.10.4.23

Articles March 2021

Correlation of Morphology and Function of Flecks Using Short-Wave Fundus Autofluorescence and Microperimetry in Patients With Stargardt Disease

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Patty P. A. Dhooge; Esmee H. Runhart; Stanley Lambertus; Nathalie M. Bax; Johannes M. M. Groenewoud; B. Jeroen Klevering; Carel B. Hoyng
TAGS: diagnostic imaging, eye, fundus autofluorescence imaging, language morphology, morphology, stargardt's disease, autofluorescence, follow-up
Trans. Vis. Sci. Tech.. 2021; 10(3):18. doi: https://doi.org/10.1167/tvst.10.3.18

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

A two-year prospective natural history study in patients with CRB1-associated retinal dystrophies: establishing clinical endpoints for future gene therapy trials

Xuan-Thanh-An Nguyen; Mays Talib; Mary J. van Schooneveld; Jan Wijnholds; Maria M. van Genderen; Ralph J. Florijn; Jacoline ten Brink; Frans P Cremers; Magda A. Meester; Caroline Klaver; L. Ingeborgh van den Born; Carel C B Hoyng; Alberta Thiadens; Arthur Bergen; Camiel Boon

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3051. doi:

Retina March 2020

Complement Activation Levels Are Related to Disease Stage in AMD

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Thomas J. Heesterbeek; Yara T. E. Lechanteur; Laura Lorés-Motta; Tina Schick; Mohamed R. Daha; Lebriz Altay; Sandra Liakopoulos; Dzenita Smailhodzic; Anneke I. den Hollander; Carel B. Hoyng; Eiko K. de Jong; B. Jeroen Klevering
TAGS: complement activation, complement system proteins, choroidal neovascularization
Invest. Ophthalmol. Vis. Sci.. 2020; 61(3):18. doi: https://doi.org/10.1167/iovs.61.3.18

Includes: Supplemental Content

Retina October 2019

Late-Onset Stargardt Disease Due to Mild, Deep-Intronic ABCA4 Alleles

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Esmee H. Runhart; Dyon Valkenburg; Stéphanie S. Cornelis; Mubeen Khan; Riccardo Sangermano; Silvia Albert; Nathalie M. Bax; Galuh D. N. Astuti; Christian Gilissen; Jan-Willem R. Pott; Joke B. G. M. Verheij; Ellen A. W. Blokland; Frans P. M. Cremers; L. Ingeborgh van den Born; Carel B. Hoyng
TAGS: alleles, introns, penetrance, genetic, stargardt's disease, cohort studies, photoreceptors, age of onset, stem cells
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4249-4256. doi: https://doi.org/10.1167/iovs.19-27524

Includes: Supplemental Content

Retina August 2019

Elevated Steroid Hormone Levels in Active Chronic Central Serous Chorioretinopathy

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Rosa L. Schellevis; Lebriz Altay; Asha Kalisingh; Timo W. F. Mulders; Vasilena Sitnilska; Carel B. Hoyng; Camiel J. F. Boon; Joannes M. M. Groenewoud; Eiko K. de Jong; Anneke I. den Hollander
TAGS: central serous chorioretinopathy, steroid hormone, steroids, hormones
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3407-3413. doi: https://doi.org/10.1167/iovs.19-26781

Includes: Supplemental Content

Retina August 2019

Foveal Sparing in Central Retinal Dystrophies

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Nathalie M. Bax; Dyon Valkenburg; Stanley Lambertus; B. Jeroen Klevering; Camiel J. F. Boon; Frank G. Holz; Frans P. M. Cremers; Monika Fleckenstein; Carel B. Hoyng; Moritz Lindner; for the Foveal Sparing Atrophy Study Team (FAST)
TAGS: atrophy, eye, fovea centralis, respiratory distress syndrome, newborn, retinal dystrophies, atrophic condition of skin, spectral domain-optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3456-3467. doi: https://doi.org/10.1167/iovs.18-26533

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Comparing the efficacy of bevacizumab to ranibizumab in patients with diabetic macular edema: the BRDME study

Maartje J.C. Vader; Ann-Sofie M.E. Schauwvlieghe; Frank D Verbraak; Greetje Dijkman; Johanna M.M. Hooymans; Leonie I. Los; Aeilko H. Zwinderman; Tunde Peto; Carel B. Hoyng; Redmer van Leeuwen; Johannes R. Vingerling; Annette C. Moll; Janneke J.C. van Lith-Verhoeven; Marcel G.W. Dijkgraaf; Reinier O. Schlingemann

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3648. doi:

ARVO Annual Meeting Abstract July 2019

AAV-mediated protein trans -splicing in the retina

Patrizia Tornabene; Ivana Trapani; Fabio Dell'Aquila; Elena Marrocco; Carlo Gesualdo; Settimio Rossi; Laura Giaquinto; Silvia Albert; Carel B. Hoyng; Elena Polishchuk; Frans P Cremers; Enrico Maria Surace; Francesca Simonelli; Antonella De Matteis; Roman Polishchuk; Alberto Auricchio

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5199. doi:

ARVO Annual Meeting Abstract July 2019

The identification of a RNA splice variant in TULP1 in two siblings with early-onset photoreceptor dystrophy

Susanne Roosing; Sanne K Verbakel; Zeinab Fadaie; Jeroen Klevering; Maria M. van Genderen; Ilse Feenstra; Frans P Cremers; Carel C B Hoyng

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):423. doi:

ARVO Annual Meeting Abstract July 2019

Metabolomics in Age-related Macular Degeneration: The EYE-RISK Consortium

Ilhan Erkin Acar; Magda Meester; Laura Lorés de Motta; Daniel Pauleikhoff; Sascha Fauser; Carel C B Hoyng; Cecile DelCourt; Caroline C W Klaver; Tessel E Galesloot; Anneke I Den Hollander

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1004. doi:

ARVO Annual Meeting Abstract July 2019

Risk factors for Fellow Eye Progression in Patients with Unilateral Exudative Age-Related Macular Degeneration

Julia Lemke; Vasilena Sitnilska; Caroline Gietzelt; Tina Schick; Carel C B Hoyng; Anneke I Den Hollander; Sascha Fauser; Lebriz Altay

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1134. doi:

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Common and rare genetic risk variants for Age-related Macular Degeneration progression in the Coimbra Eye Study.

Clinical and genetic spectrum of patients with GUCY2D -associated retinal dystrophies

X-linked retinoschisis: Long-term follow-up and genetic spectrum in 340 patients

Long-term follow-up of chronic central serous chorioretinopathy patients after primary treatment of oral eplerenone or half-dose photodynamic therapy and crossover treatment: SPECTRA trial report No. 3

Patient-reported visual functioning in persons with bi-allelic USH2A variants

Supplement intake and plasma nutritional biomarkers reduce risk for second eye progression in age-related macular degeneration.

Genetic characterization of a Portuguese age-related macular degeneration population

Long-read technologies unravel hidden inversion-duplication in a family with choroideremia

Tackling the Challenges of Product Development Through a Collaborative Rare Disease Network: The Foundation Fighting Blindness Consortium

Correlation of Morphology and Function of Flecks Using Short-Wave Fundus Autofluorescence and Microperimetry in Patients With Stargardt Disease

A two-year prospective natural history study in patients with CRB1-associated retinal dystrophies: establishing clinical endpoints for future gene therapy trials

Complement Activation Levels Are Related to Disease Stage in AMD

Late-Onset Stargardt Disease Due to Mild, Deep-Intronic ABCA4 Alleles

Elevated Steroid Hormone Levels in Active Chronic Central Serous Chorioretinopathy

Foveal Sparing in Central Retinal Dystrophies

Comparing the efficacy of bevacizumab to ranibizumab in patients with diabetic macular edema: the BRDME study

AAV-mediated protein trans -splicing in the retina

The identification of a RNA splice variant in TULP1 in two siblings with early-onset photoreceptor dystrophy

Metabolomics in Age-related Macular Degeneration: The EYE-RISK Consortium

Risk factors for Fellow Eye Progression in Patients with Unilateral Exudative Age-Related Macular Degeneration

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