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Retina November 2024

Optimization of HITI-Mediated Gene Insertion for Rhodopsin and Peripherin-2 in Mouse Rod Photoreceptors: Targeting Dominant Retinitis Pigmentosa

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Akishi Onishi; Yuji Tsunekawa; Michiko Mandai; Aiko Ishimaru; Yoko Ohigashi; Junki Sho; Kazushi Yasuda; Keiichiro Suzuki; Juan Carlos Izpisua Belmonte; Fumio Matsuzaki; Masayo Takahashi
TAGS: genes, genome editing, mice, retinitis pigmentosa, rhodopsin, rod photoreceptors, donors, plasmids, electroporation
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):38. https://doi.org/10.1167/iovs.65.13.38

Includes: Supplemental Content

Cornea January 2021

Sodium Channel Blockers Modulate Abnormal Activity of Regenerating Nociceptive Corneal Nerves After Surgical Lesion

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Carolina Luna; Kamila Mizerska; Susana Quirce; Carlos Belmonte; Juana Gallar; María del Carmen Acosta; Víctor Meseguer

Invest. Ophthalmol. Vis. Sci.. 2021; 62(1):2. https://doi.org/10.1167/iovs.62.1.2

ARVO Annual Meeting Abstract June 2020

Impulse activity of corneal cold nerve terminals modulation by ATP-gated ion channel permeant photoswitches

Juana Gallar; David Ares-Suarez; Almudena Iñigo-Portugues; Enrique Velasco; Susana Quirce; M Carmen Acosta; Carlos Belmonte; Victor M. Meseguer

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):160.

ARVO Annual Meeting Abstract July 2018

Ocular Surface Temperature in Sjögren's Syndrome

Maria L. Merino; Javier Belmonte; M Carmen Acosta; Carlos Belmonte; Juana Gallar

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):148.

ARVO Annual Meeting Abstract July 2018

Coding of small temperature changes by high-background cold thermosensitive trigeminal neurons innervating the ocular surface

Ariadna Diaz-Tahoces; Enrique Velasco; Carolina Luna García; Fernando A. Carrera; Carlos Belmonte; Juana Gallar; M Carmen Acosta

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):155.

ARVO Annual Meeting Abstract July 2018

Role of Resident Dendritic Cells on Corneal Cold Thermoreceptor Function

Yashar Seyed-Razavi; Laura Rincon Frutos; Carolina Luna García; Almudena Inigo-Portugues; M Carmen Acosta; Carlos Belmonte; Juana Gallar; Pedram Hamrah

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3309.

Cornea May 2018

Functional and Morphologic Alterations in Mechanical, Polymodal, and Cold Sensory Nerve Fibers of the Cornea Following Photorefractive Keratectomy

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Federico Bech; Omar González-González; Enol Artime; Joana Serrano; Ignacio Alcalde; Juana Gallar; Jesús Merayo-Lloves; Carlos Belmonte
TAGS: cold sensation, cold temperature, common cold, cornea, neurons, keratectomy, sensory nerves, thermoreceptors
Invest. Ophthalmol. Vis. Sci.. 2018; 59(6):2281-2292. https://doi.org/10.1167/iovs.18-24007

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Somatotopic organization of the different functional types of trigeminal ganglion neurons innervating the ocular surface and periocular tissues

Baldemar Santiago; Ariadna Diaz-Tahoces; Juana Gallar; Carlos Belmonte; M Carmen Acosta

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1020.

ARVO Annual Meeting Abstract June 2017

REMODELING OF CORNEAL COLD SENSORY NERVE FIBERS IN THE ADULT LIVING MOUSE

Almudena Íñigo-Portugués; Giovanna Exposito; Juana Gallar; Carlos Belmonte; Victor Meseguer

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1021.

Cornea January 2017

Functional Properties of Sensory Nerve Terminals of the Mouse Cornea

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Omar González-González; Federico Bech; Juana Gallar; Jesús Merayo-Lloves; Carlos Belmonte

Invest. Ophthalmol. Vis. Sci.. 2017; 58(1):404-415. https://doi.org/10.1167/iovs.16-20033

ARVO Annual Meeting Abstract September 2016

Altered Impulse Activity of Corneal Sensory Nerves Caused by Unilateral UV-induced Corneal Inflammation also Develops in the Contralateral Eye Sensory Nerves

Juana Gallar; Carolina Luna; Susana Quirce; Carlos Belmonte; M Carmen Acosta

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):429.

ARVO Annual Meeting Abstract September 2016

CORNEAL SURFACE TEMPERATURE, AND TEARING AND BLINKING RATES DURING ALLERGIC KERATOCONJUNCTIVITIS IN THE GUINEA PIG.

M Carmen Acosta; Carolina Luna; Susana Quirce; Adolfo Aracil; Carlos Belmonte; Juana Gallar

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):401.

ARVO Annual Meeting Abstract September 2016

AGING EFFECTS ON CORNEAL COLD THERMORECEPTOR NEURONS AND CORNEAL NERVES ARE RELATED WITH CHANGES IN BASAL TEARING AND BLINKING RATES

Almudena Íñigo-Portugués; Omar Gonzalez Gonzalez; Ignacio Alcalde; Federico Bech; Juana Gallar; Jesus Merayo-Lloves; Carlos Belmonte

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):402.

ARVO Annual Meeting Abstract September 2016

Morphological and functional characteristics of regenerating corneal nerves in mice following photorefractive surgery

Omar Gonzalez Gonzalez; Federico Bech; Ignacio Alcalde; Almudena Íñigo-Portugués; Jesus Merayo-Lloves; Carlos Belmonte

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):906.

ARVO Annual Meeting Abstract September 2016

Interblink corneal temperature fall is faster in Sjögren’s syndrome patients

Maria L. Merino; Javier Belmonte; M Carmen Acosta; José Rosas; Carlos Belmonte; Juana Gallar

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5689.

ARVO Annual Meeting Abstract June 2015

EFFECTS OF AGING ON NEUROCHEMICAL PROPERTIES OF MOUSE CORNEAL COLD SENSORY NEURONS, CHANGES IN MORPHOLOGY IN THEIR AFFERENT PROJECTIONS AND IMPLICATIONS IN BASAL TEAR SECRETION

Almudena Íñigo-Portugués; Ignacio Alcalde; Omar Gonzalez Gonzalez; Juana Gallar; Jesus Merayo-Lloves; Carlos Belmonte

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):290.

ARVO Annual Meeting Abstract June 2015

FUNTIONAL ACTIVITY OF CORNEAL COLD SENSORY NERVE TERMINALS AND BASAL TEARING RATE IN YOUNG AND AGED MICE

Omar Gonzalez Gonzalez; Ignacio Alcalde; Almudena Íñigo-Portugués; Juana Gallar; Jesus Merayo-Lloves; Carlos Belmonte

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):292.

ARVO Annual Meeting Abstract June 2015

Corneal infrared thermography and tear meniscus height in dry eye syndrome.

Maria L. Merino; Javier Belmonte; Jose Rosas; M Carmen Acosta; Carlos Belmonte; Juana Gallar

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):315.

ARVO Annual Meeting Abstract June 2015

Effects of the sodium channel blocker amitriptyline on the spontaneous and stimulus-evoked activity of corneal cold-sensitive nerve terminals in intact and tear-deficient guinea-pig eyes.

Takayoshi Masuoka; Carlos Belmonte; Juana Gallar

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):330.

ARVO Annual Meeting Abstract June 2015

Evaluation of tearing rate, TBUT and corneal surface temperature in aging and tear deficient guinea pig eyes.

M Carmen Acosta; Elisa Alonso; Raquel Revert; Carolina Luna; Carlos Belmonte; Juana Gallar

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4458.

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Optimization of HITI-Mediated Gene Insertion for Rhodopsin and Peripherin-2 in Mouse Rod Photoreceptors: Targeting Dominant Retinitis Pigmentosa

Sodium Channel Blockers Modulate Abnormal Activity of Regenerating Nociceptive Corneal Nerves After Surgical Lesion

Impulse activity of corneal cold nerve terminals modulation by ATP-gated ion channel permeant photoswitches

Ocular Surface Temperature in Sjögren's Syndrome

Coding of small temperature changes by high-background cold thermosensitive trigeminal neurons innervating the ocular surface

Role of Resident Dendritic Cells on Corneal Cold Thermoreceptor Function

Functional and Morphologic Alterations in Mechanical, Polymodal, and Cold Sensory Nerve Fibers of the Cornea Following Photorefractive Keratectomy

Somatotopic organization of the different functional types of trigeminal ganglion neurons innervating the ocular surface and periocular tissues

REMODELING OF CORNEAL COLD SENSORY NERVE FIBERS IN THE ADULT LIVING MOUSE

Functional Properties of Sensory Nerve Terminals of the Mouse Cornea

Altered Impulse Activity of Corneal Sensory Nerves Caused by Unilateral UV-induced Corneal Inflammation also Develops in the Contralateral Eye Sensory Nerves

CORNEAL SURFACE TEMPERATURE, AND TEARING AND BLINKING RATES DURING ALLERGIC KERATOCONJUNCTIVITIS IN THE GUINEA PIG.

AGING EFFECTS ON CORNEAL COLD THERMORECEPTOR NEURONS AND CORNEAL NERVES ARE RELATED WITH CHANGES IN BASAL TEARING AND BLINKING RATES

Morphological and functional characteristics of regenerating corneal nerves in mice following photorefractive surgery

Interblink corneal temperature fall is faster in Sjögren’s syndrome patients

EFFECTS OF AGING ON NEUROCHEMICAL PROPERTIES OF MOUSE CORNEAL COLD SENSORY NEURONS, CHANGES IN MORPHOLOGY IN THEIR AFFERENT PROJECTIONS AND IMPLICATIONS IN BASAL TEAR SECRETION

FUNTIONAL ACTIVITY OF CORNEAL COLD SENSORY NERVE TERMINALS AND BASAL TEARING RATE IN YOUNG AND AGED MICE

Corneal infrared thermography and tear meniscus height in dry eye syndrome.

Effects of the sodium channel blocker amitriptyline on the spontaneous and stimulus-evoked activity of corneal cold-sensitive nerve terminals in intact and tear-deficient guinea-pig eyes.

Evaluation of tearing rate, TBUT and corneal surface temperature in aging and tear deficient guinea pig eyes.

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