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ARVO Annual Meeting Abstract July 2018

Aflibercept in combination with nesvacumab (anti-Ang2) induces vascular remodeling in a rabbit model of pathological neovascularization.

Bibiana Iglesias; Thomas MacPherson; Jingtai Cao; Carmelo Romano

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1447. doi:

ARVO Annual Meeting Abstract July 2018

Effect of Anti-Human C5 Antibodies on Ocular Inflammation in Experimental Autoimmune Uveitis in Humanized C5 Mice Aixu Sun, Henry Chen, Hua Yang, Adrianna Latuszek, Ying Hu, Pamela Krueger, Tammy Huang, Jingtai Cao, Carmelo Romano Regeneron Pharmaceuticals, Inc. Tarrytown, NY

Aixu Sun; Henry Chen; Hua Yang; Adrianna Latuszek; Ying Hu; Pamela Krueger; Tammy Huang; Jingtai Cao; Carmelo Romano

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2534. doi:

ARVO Annual Meeting Abstract July 2018

Wild Type and Mutant Retinoschisin Subunits Co-assemble When Expressed in the Same Cells

Duo Sun; Yang Liu; Nicole Zazzarino; Jifang Tao; Joel Martin; William Olson; Jingtai Cao; Carmelo Romano

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3050. doi:

ARVO Annual Meeting Abstract July 2018

VEGFR1 inhibition hinders developmental retinal vessel outgrowth in pups and reduces pathological neovascularization in OIR model in mice

Eunice Cheung; Jingtai Cao; Carmelo Romano

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5461. doi:

ARVO Annual Meeting Abstract July 2018

Neuroprotective effect of TrkB agonist antibody in humanized TrkB rat

Henry Chen; Adrianna Latuszek; Ying Hu; Jeffrey Lee; William Poueymirou; Jingtai Cao; William Olson; Brian Zambrowicz; Carmelo Romano

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6134. doi:

Retina February 2018

Aflibercept Action in a Rabbit Model of Chronic Retinal Neovascularization: Reversible Inhibition of Pathologic Leakage With Dose-Dependent Duration

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Jingtai Cao; Thomas C. MacPherson; Bibiana V. Iglesias; Yang Liu; Natasha Tirko; George D. Yancopoulos; Stanley J. Wiegand; Carmelo Romano
TAGS: injection of therapeutic agent, oryctolagus cuniculus, retinal neovascularization, diagnostic imaging, eye, aflibercept, anti-vascular endothelial growth factor therapy
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):1033-1044. doi: 10.1167/iovs.17-22897

ARVO Annual Meeting Abstract September 2016

Angiopoietin-like 3 (ANGPTL3) Does not Induce Corneal Neovascularization (CoNV) after Intrastromal Injection of Plasmid DNA Encoding ANGPTL3 in Mice

Duo Sun; hong li; Yang Liu; Panayiotis Stevis; Viktoria Gusarova; Carmelo Romano; Jingtai Cao

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3532. doi:

ARVO Annual Meeting Abstract September 2016

Inhibiting Platelet Derived Growth Factor Receptor β (PDGFRβ) affects vessel morphology and growth of developing retinal vessels, and induces leucocyte infiltration in mice

Eunice Cheung; Stanley J Wiegand; Jingtai Cao; Carmelo Romano; Ivan B Lobov

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4605. doi:

ARVO Annual Meeting Abstract September 2016

In vivo assessment of the impact of neutralizing antibodies on intravitreal AAV2.7m8 administration

Annahita Keravala; Kathryn W Woodburn; Sharmila Vijay; Carmelo Romano; Stanley J Wiegand; Andrew Murphy; Thomas Walter Chalberg; Mehdi Gasmi

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):782. doi:

ARVO Annual Meeting Abstract September 2016

Evaluation of AAV Variants for Transgene Expression and Distribution in Rabbits and Non-Human Primate Eyes Following Intravitreal Delivery

Bibiana Veronica Iglesias; Kathryn W Woodburn; Jingtai Cao; Stanley J Wiegand; Annahita Keravala; Carmelo Romano; Mehdi Gasmi

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):786. doi:

Retina July 2012

A Phage Display-Based Approach to Investigate Abnormal Neovessels of the Retina

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Magdalena Staniszewska; Xiaolin Gu; Carmelo Romano; Andrius Kazlauskas
TAGS: bacteriophages, peptides, retina
Invest. Ophthalmol. Vis. Sci.. 2012; 53(8):4371-4379. doi: 10.1167/iovs.12-9690

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract March 2012

AL-78898A Inhibits Complement Deposition in a Primate Light Damage Model

Robert J. Collier; Sherry Smith; Hayden Hoang; Elizabeth Martin; Yu Wang; Li Zhu; Richard Ornberg; Carmelo Romano

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):5362. doi:

Retinal Cell Biology October 2011

Complement Deposition and Microglial Activation in the Outer Retina in Light-Induced Retinopathy: Inhibition by a 5-HT 1A Agonist

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Robert J. Collier; Yu Wang; Sherry S. Smith; Elizabeth Martin; Richard Ornberg; Kristina Rhoades; Carmelo Romano
TAGS: serotonin, complement system proteins, microglia, retinal diseases, retina, agonists, light exposure, blue light
Invest. Ophthalmol. Vis. Sci.. 2011; 52(11):8108-8116. doi: 10.1167/iovs.10-6418

ARVO Annual Meeting Abstract April 2011

Molecular Characterization of Subretinal Fibrosis in Human Eyes with AMD

David P. Bingaman; Jasmine Hernandez; Carmelo Romano; Robert F. Mullins

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):1762. doi:

Retinal Cell Biology April 2011

Agonists at the Serotonin Receptor (5-HT 1A ) Protect the Retina from Severe Photo-Oxidative Stress

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Robert J. Collier; Yamini Patel; Elizabeth A. Martin; Olga Dembinska; Mark Hellberg; D. Scott Krueger; Michael A. Kapin; Carmelo Romano
TAGS: serotonin, serotonin receptor, rats, retina, stress, agonists, blue light
Invest. Ophthalmol. Vis. Sci.. 2011; 52(5):2118-2126. doi: 10.1167/iovs.10-6304

Retinal Cell Biology December 2004

Susceptibilities to and Mechanisms of Excitotoxic Cell Death of Adult Mouse Inner Retinal Neurons in Dissociated Culture

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Xianmin Luo; Akemichi Baba; Toshio Matsuda; Carmelo Romano
TAGS: adult, amacrine cells, cell death, ganglia, neurons, mice, agonists, glutamate
Invest. Ophthalmol. Vis. Sci.. 2004; 45(12):4576-4582. doi: 10.1167/iovs.04-0166

Glaucoma May 2001

Serum Autoantibody against Glutathione S -Transferase in Patients with Glaucoma

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Junjie Yang; Gülgün Tezel; Rajkumar V. Patil; Carmelo Romano; Martin B. Wax
TAGS: western blotting, glaucoma, glutathione, autoantibodies, transferase, proteins
Invest. Ophthalmol. Vis. Sci.. 2001; 42(6):1273-1276. doi:

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Aflibercept in combination with nesvacumab (anti-Ang2) induces vascular remodeling in a rabbit model of pathological neovascularization.

Effect of Anti-Human C5 Antibodies on Ocular Inflammation in Experimental Autoimmune Uveitis in Humanized C5 Mice Aixu Sun, Henry Chen, Hua Yang, Adrianna Latuszek, Ying Hu, Pamela Krueger, Tammy Huang, Jingtai Cao, Carmelo Romano Regeneron Pharmaceuticals, Inc. Tarrytown, NY

Wild Type and Mutant Retinoschisin Subunits Co-assemble When Expressed in the Same Cells

VEGFR1 inhibition hinders developmental retinal vessel outgrowth in pups and reduces pathological neovascularization in OIR model in mice

Neuroprotective effect of TrkB agonist antibody in humanized TrkB rat

Aflibercept Action in a Rabbit Model of Chronic Retinal Neovascularization: Reversible Inhibition of Pathologic Leakage With Dose-Dependent Duration

Angiopoietin-like 3 (ANGPTL3) Does not Induce Corneal Neovascularization (CoNV) after Intrastromal Injection of Plasmid DNA Encoding ANGPTL3 in Mice

Inhibiting Platelet Derived Growth Factor Receptor β (PDGFRβ) affects vessel morphology and growth of developing retinal vessels, and induces leucocyte infiltration in mice

In vivo assessment of the impact of neutralizing antibodies on intravitreal AAV2.7m8 administration

Evaluation of AAV Variants for Transgene Expression and Distribution in Rabbits and Non-Human Primate Eyes Following Intravitreal Delivery

A Phage Display-Based Approach to Investigate Abnormal Neovessels of the Retina

AL-78898A Inhibits Complement Deposition in a Primate Light Damage Model

Complement Deposition and Microglial Activation in the Outer Retina in Light-Induced Retinopathy: Inhibition by a 5-HT 1A Agonist

Molecular Characterization of Subretinal Fibrosis in Human Eyes with AMD

Agonists at the Serotonin Receptor (5-HT 1A ) Protect the Retina from Severe Photo-Oxidative Stress

Susceptibilities to and Mechanisms of Excitotoxic Cell Death of Adult Mouse Inner Retinal Neurons in Dissociated Culture

Serum Autoantibody against Glutathione S -Transferase in Patients with Glaucoma

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