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ARVO Imaging in the Eye Conference Abstract July 2020

Segmentation of the RPE-BM complex on OCT imaging from multiple devices based on convolutional neural networks

Danilo Andrade De Jesus; Sander Wooning; Daniël Luttikhuizen; Muhammad Shirazi; Michael Pircher; Caroline Klaver; Johannes R. Vingerling; Stefan Klein; Theo van Walsum; Luisa Sanchez Brea

Invest. Ophthalmol. Vis. Sci.. 2020; 61(9):PB00104. doi:

ARVO Annual Meeting Abstract June 2020

Gene-based Rare Variant Tests Identify Multiple Genome-wide Significant Associations with Refractive Error in Europeans

Anthony Musolf; Annechien E. G. Haarman; Deyana Lewis; Virginie J.M. Verhoeven; Caroline Klaver; Joan E Bailey-Wilson

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):92. doi:

ARVO Annual Meeting Abstract June 2020

Systemic metformin use reduces open-angle glaucoma risk

Joëlle Vergroesen; Bruno HC Stricker; Arfan M Ikram; Maryam Kavousi; Albert Hofman; Caroline Klaver; Wishal Ramdas

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):656. doi:

ARVO Annual Meeting Abstract June 2020

Phenotypic consequences of GJD2, the first GWAS hit for common myopia

Annechien Haarman; Clair Enthoven; Jan Keunen; Camiel Boon; Annette Geerards; Gregorius P M Luyten; The Erasmus MC Myopia Research Group Rotterdam; Virginie J.M. Verhoeven; Caroline Klaver

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):850. doi:

ARVO Annual Meeting Abstract June 2020

Axial length growth from 6 to 13 years of age and risk of myopia at age 13: the Generation R study

Willem Tideman; Clair Enthoven; Vincent Jaddoe; Jan Roelof (JR) Polling; Caroline Klaver

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):852. doi:

ARVO Annual Meeting Abstract June 2020

Atropine for myopia progression: high dose vs low dose in a real-world setting

Jan Roelof (JR) Polling; Emily Tan; Willem Tideman; Caroline Klaver

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1134. doi:

ARVO Annual Meeting Abstract June 2020

A large cross-ancestry meta-analysis of genome-wide association studies identifies 69 novel risk loci for primary open-angle glaucoma, and shows a genetic link to Alzheimer’s disease.

Janey Wiggs; Puya Gharahkhani; Eric Jorgenson; Pirro G Hysi; Anthony Khawaja; Sarah Pendergrass; Xikun Han; David Mackey; Christopher Hammond; Michael A Hauser; Louis R Pasquale; Caroline Klaver; Michiaki Kubo; Tin Aung; Jamie E Craig; Stuart MacGregor

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1890. doi:

ARVO Annual Meeting Abstract June 2020

The phenotype of the ARMS2 risk variant in age-related macular degeneration. Findings from the E3 & EYE-RISK consortium

Eric F. Thee; Johanna Colijn; Magda A. Meester; Anneke Den Hollander; Timo Verzijden; Caroline Klaver

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2312. doi:

ARVO Annual Meeting Abstract June 2020

Diagnostic exome sequencing in 50 patients with high myopia

Virginie Verhoeven; Annechien Haarman; Jan Roelof (JR) Polling; Marianne van Tienhoven; Alberta Thiadens; Sjoukje E Loudon; Arjan Bouman; Anneke JA Kievit; Lies H Hoefsloot; Caroline Klaver

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2673. doi:

ARVO Annual Meeting Abstract June 2020

A two-year prospective natural history study in patients with CRB1-associated retinal dystrophies: establishing clinical endpoints for future gene therapy trials

Xuan-Thanh-An Nguyen; Mays Talib; Mary J. van Schooneveld; Jan Wijnholds; Maria M. van Genderen; Ralph J. Florijn; Jacoline ten Brink; Frans P Cremers; Magda A. Meester; Caroline Klaver; L. Ingeborgh van den Born; Carel C B Hoyng; Alberta Thiadens; Arthur Bergen; Camiel Boon

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3051. doi:

ARVO Annual Meeting Abstract June 2020

Genotype-phenotype correlation in geographic atrophy secondary to age-related macular degeneration. The EYE-RISK Consortium

Marc Biarnes Perez; Johanna Colijn; Jose Sousa; Lucia Ferraro; Míriam Garcia; Timo Verzijden; Magda A. Meester; Cecile Delcourt; Caroline Klaver; Anneke Den Hollander; Imre Lengyel; Tunde Peto; Jordi Monés

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3520. doi:

ARVO Annual Meeting Abstract June 2020

Estimating Uncertainty of Deep Neural Networks for Age-related Macular Degeneration Grading using Optical Coherence Tomography

Coen de Vente; Mark van Grinsven; carlos ciller; Sandro De Zanet; Agata Mosinska; Raphael Sznitman; Caroline Klaver; Clara I Sanchez

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1630. doi:

ARVO Annual Meeting Abstract June 2020

Assessing the natural course of keratoconus using Scheimpflug based tomography

Mahmoud M.M.A. Habeeb; Annette Geerards; Magda A. Meester; Caroline Klaver; Wishal Ramdas; Bart T H Van Dooren

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4063. doi:

Review April 2020

The Complications of Myopia: A Review and Meta-Analysis

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Annechien E. G. Haarman; Clair A. Enthoven; J. Willem L. Tideman; Milly S. Tedja; Virginie J. M. Verhoeven; Caroline C. W. Klaver
TAGS: meta-analysis, myopia
Invest. Ophthalmol. Vis. Sci.. 2020; 61(4):49. doi: https://doi.org/10.1167/iovs.61.4.49

Includes: Supplemental Content

Special Issue April 2020

Performance of Classification Systems for Age-Related Macular Degeneration in the Rotterdam Study

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Eric F. Thee; Magda A. Meester-Smoor; Daniel T. Luttikhuizen; Johanna M. Colijn; Clair A. Enthoven; Annechien E. G. Haarman; Dimitris Rizopoulos; Caroline C. W. Klaver; for the EyeNED Reading Center
TAGS: age-related macular degeneration, drusen, incidence
Trans. Vis. Sci. Tech.. 2020; 9(2):26. doi: https://doi.org/10.1167/tvst.9.2.26

Includes: Supplemental Content

Clinical and Epidemiologic Research February 2020

Evidence That Emmetropization Buffers Against Both Genetic and Environmental Risk Factors for Myopia

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Alfred Pozarickij; Clair A. Enthoven; Neema Ghorbani Mojarrad; Denis Plotnikov; Milly S. Tedja; Annechien E.G. Haarman; J. Willem L. Tideman; Jan Roelof Polling; Kate Northstone; Cathy Williams; Caroline C. W. Klaver; Jeremy A. Guggenheim
TAGS: alspac study, buffers, child, environmental factors, genetics, myopia, refractive errors, risk factors, parent, cohort studies
Invest. Ophthalmol. Vis. Sci.. 2020; 61(2):41. doi: https://doi.org/10.1167/iovs.61.2.41

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Metabolomics in Age-related Macular Degeneration: The EYE-RISK Consortium

Ilhan Erkin Acar; Magda Meester; Laura Lorés de Motta; Daniel Pauleikhoff; Sascha Fauser; Carel C B Hoyng; Cecile DelCourt; Caroline C W Klaver; Tessel E Galesloot; Anneke I Den Hollander

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1004. doi:

ARVO Annual Meeting Abstract July 2019

Automated grading of fundus photographs to identify referable AMD for first-line eye care

Eric Ferdinand Thee; Mark J. van Grinsven; Timo Verzijden; Daniel T. Luttikhuizen; Magda Meester; Johanna Maria Colijn; Clara I Sanchez; Caroline C W Klaver

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1532. doi:

ARVO Annual Meeting Abstract July 2019

Development of a Genotyping Assay for Age-Related Macular Degeneration: The EYE-RISK Consortium

Anita de Breuk; Ilhan Erkin Acar; Magda Meester; Mascha MVAP Schijvenaars; Eveline Kersten; Jordi Mones; Daniel Pauleikhoff; Rufino Silva; Sascha Fauser; Carel C B Hoyng; Cecile DelCourt; Caroline C W Klaver; Marieke JH Coenen; Anneke I Den Hollander

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2955. doi:

ARVO Annual Meeting Abstract July 2019

Genetic risk scores of the largest multi-trait GWAS meta-analysis on refractive errors

Caroline C W Klaver; Milly S. Tedja; Xikun Han; Virginie JM Verhoeven; Nick Ericksson; Nick Furlotte; Najaf Amin; Cornelia van Duijn; Stuart MacGregor

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3143. doi:

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Segmentation of the RPE-BM complex on OCT imaging from multiple devices based on convolutional neural networks

Gene-based Rare Variant Tests Identify Multiple Genome-wide Significant Associations with Refractive Error in Europeans

Systemic metformin use reduces open-angle glaucoma risk

Phenotypic consequences of GJD2, the first GWAS hit for common myopia

Axial length growth from 6 to 13 years of age and risk of myopia at age 13: the Generation R study

Atropine for myopia progression: high dose vs low dose in a real-world setting

A large cross-ancestry meta-analysis of genome-wide association studies identifies 69 novel risk loci for primary open-angle glaucoma, and shows a genetic link to Alzheimer’s disease.

The phenotype of the ARMS2 risk variant in age-related macular degeneration. Findings from the E3 & EYE-RISK consortium

Diagnostic exome sequencing in 50 patients with high myopia

A two-year prospective natural history study in patients with CRB1-associated retinal dystrophies: establishing clinical endpoints for future gene therapy trials

Genotype-phenotype correlation in geographic atrophy secondary to age-related macular degeneration. The EYE-RISK Consortium

Estimating Uncertainty of Deep Neural Networks for Age-related Macular Degeneration Grading using Optical Coherence Tomography

Assessing the natural course of keratoconus using Scheimpflug based tomography

The Complications of Myopia: A Review and Meta-Analysis

Performance of Classification Systems for Age-Related Macular Degeneration in the Rotterdam Study

Evidence That Emmetropization Buffers Against Both Genetic and Environmental Risk Factors for Myopia

Metabolomics in Age-related Macular Degeneration: The EYE-RISK Consortium

Automated grading of fundus photographs to identify referable AMD for first-line eye care

Development of a Genotyping Assay for Age-Related Macular Degeneration: The EYE-RISK Consortium

Genetic risk scores of the largest multi-trait GWAS meta-analysis on refractive errors

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