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Clinical and Epidemiologic Research February 2020

Evidence That Emmetropization Buffers Against Both Genetic and Environmental Risk Factors for Myopia

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Alfred Pozarickij; Clair A. Enthoven; Neema Ghorbani Mojarrad; Denis Plotnikov; Milly S. Tedja; Annechien E.G. Haarman; J. Willem L. Tideman; Jan Roelof Polling; Kate Northstone; Cathy Williams; Caroline C. W. Klaver; Jeremy A. Guggenheim
TAGS: alspac study, buffers, child, environmental factors, genetics, myopia, refractive errors, risk factors, parent, cohort studies
Invest. Ophthalmol. Vis. Sci.. 2020; 61(2):41. doi: https://doi.org/10.1167/iovs.61.2.41

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

A registry and research database for retinal dystrophies – the RD5000 database

Magda Meester; Maikel Vermeer; Camiel Boon; Maria M. van Genderen; Carel C B Hoyng; Frans P Cremers; Clasien Oomen; Alberta A H J Thiadens; Jan-Willem R. Pott; Mary J van Schooneveld; Caroline C W Klaver; L. Ingeborgh van den Born

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3962. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Grading of retinal complications in high myopia occurring in Europeans

Annechien Haarman; Milly S. Tedja; Corina Brussee; Gwyneth A van Rijn; Johannes R. Vingerling; Jan Keunen; Camiel Boon; Annette J.M. Geerards; Gregorius P.M. Luyten; Virginie JM Verhoeven; Caroline C W Klaver

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4349. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

The disease course of rhodopsin (RHO) -associated retinitis pigmentosa (RP): a follow-up study

Xuan-Thanh-An Nguyen; Mays Talib; Mary J van Schooneveld; Caroline Van Cauwenbergh; Jacoline B ten Brink; Ralph J Florijn; Nicoline Schalij-Delfos; Maria M. van Genderen; Frans P Cremers; L. Ingeborgh van den Born; Alberta A H J Thiadens; Carel C B Hoyng; Caroline C W Klaver; Arthur A Bergen; Bart P Leroy; Camiel Boon

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4505. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Metabolomics in Age-related Macular Degeneration: The EYE-RISK Consortium

Ilhan Erkin Acar; Magda Meester; Laura Lorés de Motta; Daniel Pauleikhoff; Sascha Fauser; Carel C B Hoyng; Cecile DelCourt; Caroline C W Klaver; Tessel E Galesloot; Anneke I Den Hollander

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1004. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Automated grading of fundus photographs to identify referable AMD for first-line eye care

Eric Ferdinand Thee; Mark J. van Grinsven; Timo Verzijden; Daniel T. Luttikhuizen; Magda Meester; Johanna Maria Colijn; Clara I Sanchez; Caroline C W Klaver

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1532. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Development of a Genotyping Assay for Age-Related Macular Degeneration: The EYE-RISK Consortium

Anita de Breuk; Ilhan Erkin Acar; Magda Meester; Mascha MVAP Schijvenaars; Eveline Kersten; Jordi Mones; Daniel Pauleikhoff; Rufino Silva; Sascha Fauser; Carel C B Hoyng; Cecile DelCourt; Caroline C W Klaver; Marieke JH Coenen; Anneke I Den Hollander

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2955. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Genetic risk scores of the largest multi-trait GWAS meta-analysis on refractive errors

Caroline C W Klaver; Milly S. Tedja; Xikun Han; Virginie JM Verhoeven; Nick Ericksson; Nick Furlotte; Najaf Amin; Cornelia van Duijn; Stuart MacGregor

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3143. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Development of a prediction model for advanced age-related macular degeneration using a penalized machine learning approach: the EYE-RISK project

Soufiane Ajana; Audrey Cougnard-Gregoire; Benedicte MJ Merle; Timo Verzijden; Magda Meester; Boris Hejblum; Johanna Maria Colijn; Jean-Francois Korobelnik; Caroline C W Klaver; Hélène Jacqmin-Gadda; Cecile DelCourt

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4799. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Effect of the age of myopia onset, environmental factors and genetic risk on myopia in the CREAM Consortium

Katie Williams; Pirro G Hysi; Sonoko Sensaki; Willem Tideman; Seyhan Yazar; juho wedenoja; Mingguang He; Olavi Parssinen; David A Mackey; Caroline C W Klaver; Christopher J Hammond; Seang-Mei Saw

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5226. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

The impact of computers on myopia in 6 to 9 year old school children.

Clair Enthoven; Willem Tideman; Jan Roelof Polling; Virginie JM Verhoeven; Caroline C W Klaver

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5831. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Opening the “black box” of deep learning in automated screening of eye diseases

Cristina González-Gonzalo; Bart Liefers; Akshayaa Vaidyanathan; Harm van Zeeland; Caroline C W Klaver; Clara I Sanchez

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1443. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Prediction of areas at risk of developing geographic atrophy in color fundus images using deep learning

Bart Liefers; Johanna Maria Colijn; Cristina González-Gonzalo; Akshayaa Vaidyanathan; Harm van Zeeland; Paul Mitchell; Caroline C W Klaver; Clara I Sanchez

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1455. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

EyeNED workstation: Development of a multi-modal vendor-independent application for annotation, spatial alignment and analysis of retinal images

Harm van Zeeland; James Meakin; Bart Liefers; Cristina González-Gonzalo; Akshayaa Vaidyanathan; Bram van Ginneken; Caroline C W Klaver; Clara I Sanchez

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6118. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Validation of lens-induced myopia protocols in C57BL/6 mice

Emilie van der Sande; Beerend Winkelman; Chris de Zeeuw; Caroline C W Klaver

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5867. doi: https://doi.org/

Genetics July 2019

Determining Possible Shared Genetic Architecture Between Myopia and Primary Open-Angle Glaucoma

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Adriana I. Iglesias; Jue Sheng Ong; Anthony P. Khawaja; Puya Gharahkhani; Milly S. Tedja; Virginie J. M. Verhoeven; Pieter W. M. Bonnemaijer; Roger C. W. Wolfs; Terri L. Young; Nomdo M. Jansonius; Jamie E. Craig; Dwight Stambolian; Cornelia M. van Duijn; Stuart MacGregor; Caroline C. W. Klaver; for the International Glaucoma Genetics Consortium (IGGC) and Consortium for Refractive Error and Myopia (CREAM)
TAGS: myopia, open-angle glaucoma, genetics
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):3142-3149. doi: https://doi.org/10.1167/iovs.18-26231

Includes: Supplemental Content

Genetics May 2019

Extending the Spectrum of EYS -Associated Retinal Disease to Macular Dystrophy

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Laurence H. M. Pierrache; Muriël Messchaert; Alberta A. H. J. Thiadens; Lonneke Haer-Wigman; Yvonne de Jong-Hesse; Wendy A. G. van Zelst-Stams; Rob W. J. Collin; Caroline C. W. Klaver; L. Ingeborgh van den Born
TAGS: phenotype, genotype, retinal diseases, vision, macular dystrophy
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):2049-2063. doi: https://doi.org/10.1167/iovs.18-25531

Includes: Supplemental Content

Genetics March 2019

Macular Dystrophy and Cone-Rod Dystrophy Caused by Mutations in the RP1 Gene: Extending the RP1 Disease Spectrum

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Sanne K. Verbakel; Ramon A. C. van Huet; Anneke I. den Hollander; Maartje J. Geerlings; Eveline Kersten; B. Jeroen Klevering; Caroline C. W. Klaver; Astrid S. Plomp; Nieneke L. Wesseling; Arthur A. B. Bergen; Konstantinos Nikopoulos; Carlo Rivolta; Yasuhiro Ikeda; Koh-Hei Sonoda; Yuko Wada; Camiel J. F. Boon; Toru Nakazawa; Carel B. Hoyng; Koji M. Nishiguchi
TAGS: phenotype, mutation, family, genes, retinitis pigmentosa, genetics, age-related macular degeneration, macular dystrophy
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):1192-1203. doi: https://doi.org/10.1167/iovs.18-26084

Includes: Supplemental Content

Special Issue February 2019

IMI – Myopia Control Reports Overview and Introduction

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James S. Wolffsohn; Daniel Ian Flitcroft; Kate L. Gifford; Monica Jong; Lyndon Jones; Caroline C. W. Klaver; Nicola S. Logan; Kovin Naidoo; Serge Resnikoff; Padmaja Sankaridurg; Earl L. Smith, III; David Troilo; Christine F. Wildsoet
TAGS: myopia
Invest. Ophthalmol. Vis. Sci.. 2019; 60(3):M1-M19. doi: https://doi.org/10.1167/iovs.18-25980

Special Issue February 2019

IMI – Myopia Genetics Report

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Milly S. Tedja; Annechien E. G. Haarman; Magda A. Meester-Smoor; Jaakko Kaprio; David A. Mackey; Jeremy A. Guggenheim; Christopher J. Hammond; Virginie J. M. Verhoeven; Caroline C. W. Klaver; for the CREAM Consortium
TAGS: genes, myopia, refractive errors, genetics, genome-wide association study, universities
Invest. Ophthalmol. Vis. Sci.. 2019; 60(3):M89-M105. doi: https://doi.org/10.1167/iovs.18-25965

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Evidence That Emmetropization Buffers Against Both Genetic and Environmental Risk Factors for Myopia

A registry and research database for retinal dystrophies – the RD5000 database

Grading of retinal complications in high myopia occurring in Europeans

The disease course of rhodopsin (RHO) -associated retinitis pigmentosa (RP): a follow-up study

Metabolomics in Age-related Macular Degeneration: The EYE-RISK Consortium

Automated grading of fundus photographs to identify referable AMD for first-line eye care

Development of a Genotyping Assay for Age-Related Macular Degeneration: The EYE-RISK Consortium

Genetic risk scores of the largest multi-trait GWAS meta-analysis on refractive errors

Development of a prediction model for advanced age-related macular degeneration using a penalized machine learning approach: the EYE-RISK project

Effect of the age of myopia onset, environmental factors and genetic risk on myopia in the CREAM Consortium

The impact of computers on myopia in 6 to 9 year old school children.

Opening the “black box” of deep learning in automated screening of eye diseases

Prediction of areas at risk of developing geographic atrophy in color fundus images using deep learning

EyeNED workstation: Development of a multi-modal vendor-independent application for annotation, spatial alignment and analysis of retinal images

Validation of lens-induced myopia protocols in C57BL/6 mice

Determining Possible Shared Genetic Architecture Between Myopia and Primary Open-Angle Glaucoma

Extending the Spectrum of EYS -Associated Retinal Disease to Macular Dystrophy

Macular Dystrophy and Cone-Rod Dystrophy Caused by Mutations in the RP1 Gene: Extending the RP1 Disease Spectrum

IMI – Myopia Control Reports Overview and Introduction

IMI – Myopia Genetics Report

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