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Meeting Abstract (12)
Journal Articles (5)

Journal

Investigative Ophthalmology & Visual Science (17)

Article Type

ARVO Annual Meeting Abstract (12)
Glaucoma (4)
Biochemistry and Molecular Biology (1)

Topics

Eye Anatomy and Disorders (4)
Glaucoma (4)
Retina (4)
Visual Neuroscience (4)
Biochemistry and Molecular Biology (3)
Genetics (3)
Eye Injuries / Ocular Trauma (1)
Immunology and Microbiology (1)
Oncology (1)

Tags

mice (4)
optic nerve (4)
apoptosis (3)
retina (3)
ganglia (2)
histone deacetylase (2)
histones (2)
immunohistochemistry (2)
retinal ganglion cells (2)
atrophy (1)

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Glaucoma August 2021

Increased Susceptibility and Intrinsic Apoptotic Signaling in Neurons by Induced HDAC3 Expression

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Heather M. Schmitt; Rachel L. Fehrman; Margaret E. Maes; Huan Yang; Lian-Wang Guo; Cassandra L. Schlamp; Heather R. Pelzel; Robert W. Nickells
TAGS: apoptosis, disease susceptibility, immunohistochemistry, mice, neurons, plasmids, signal transduction, proteins, caspase-3, histone deacetylase
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):14. doi: https://doi.org/10.1167/iovs.62.10.14

Includes: Supplemental Content

Glaucoma December 2017

AAV2-Mediated Transduction of the Mouse Retina After Optic Nerve Injury

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Robert W. Nickells; Heather M. Schmitt; Margaret E. Maes; Cassandra L. Schlamp
TAGS: mice, optic nerve, optic nerve injuries, retina, eye
Invest. Ophthalmol. Vis. Sci.. 2017; 58(14):6091-6104. doi: https://doi.org/10.1167/iovs.17-22634

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Characteristics of AAV2 mediated gene transfer in retinas after optic nerve injury

Robert W Nickells; Cassandra Schlamp; Heather M Schmitt

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4081. doi:

ARVO Annual Meeting Abstract June 2017

Overexpression of histone deacetylase 3 (HDAC3) induces apoptosis in differentiated retinal neurons

Heather M Schmitt; Cassandra Schlamp; Huan Yang; Lian-Wang Guo; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2539. doi:

ARVO Annual Meeting Abstract September 2016

Comparison of Transcriptomes of Models of Optic Nerve Injury

Ryan Donahue; Cassandra Schlamp; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4787. doi:

ARVO Annual Meeting Abstract September 2016

Characterization of the preservative effects of UW cold storage solution on mouse eyes harvested for whole eye transplants

Robert W Nickells; Cassandra Schlamp; Heather M Schmitt; Bikash R Pattnaik

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):706. doi:

ARVO Annual Meeting Abstract September 2016

Systemic dosing of an HDAC3-selective inhibitor prevents retinal ganglion cell nuclear atrophy and apoptosis after optic nerve injury

Heather M Schmitt; Cassandra Schlamp; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2554. doi:

ARVO Annual Meeting Abstract June 2015

Pannexin 1 expression in macroglia modulates their activation after optic nerve crush

Caitlin Mac Nair; Cassandra Schlamp; Valery I Shestopalov; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4948. doi:

ARVO Annual Meeting Abstract June 2015

BAX Oligomerization Kinetics and its Role in Retinal Ganglion Cell Death

Margaret Maes; Cassandra Schlamp; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4952. doi:

ARVO Annual Meeting Abstract June 2015

Small molecule inhibition of Histone Deacetylase 3 (HDAC3) reduces RGC damage and apoptosis induced by acute optic nerve injury

Heather Schmitt; Cassandra Schlamp; Robert W Nickells

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2425. doi:

ARVO Annual Meeting Abstract June 2013

The role of Rgcs1 gene Spink2 in Autophagy and ganglion cell susceptibility to optic nerve damage

Margaret Maes; Joel Dietz; Cassandra Schlamp; Robert Nickells

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1601. doi:

ARVO Annual Meeting Abstract June 2013

Adenosine triphosphate (ATP) Signaling Pathways Trigger Glial Activation in the Mouse Retina

Caitlin Mac Nair; Cassandra Schlamp; Robert Nickells

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):286. doi:

ARVO Annual Meeting Abstract June 2013

Histone Deacetylase 3 (HDAC3) plays an important role in retinal ganglion cell death after acute optic nerve injury

Heather Schmitt; Cassandra Schlamp; Robert Nickells

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):6112. doi:

Glaucoma March 2013

Nuclear Atrophy of Retinal Ganglion Cells Precedes the Bax -Dependent Stage of Apoptosis

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Katherine T. Janssen; Caitlin E. Mac Nair; Joel A. Dietz; Cassandra L. Schlamp; Robert W. Nickells
TAGS: atrophy, ganglia, mice, optic nerve, retinal ganglion cells, apoptosis, retina
Invest. Ophthalmol. Vis. Sci.. 2013; 54(3):1805-1815. doi: https://doi.org/10.1167/iovs.11-9310

Includes: Supplemental Content

ARVO Annual Meeting Abstract March 2012

Attenuated Glial Activation After Optic Nerve Crush In Bax-deficient Mice

Caitlin E. Mac Nair; Cassandra L. Schlamp; Robert W. Nickells

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3871. doi:

Glaucoma March 2012

Silencing of Fem1c R3 Gene Expression in the DBA/2J Mouse Precedes Retinal Ganglion Cell Death and Is Associated with Histone Deacetylase Activity

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Heather R. Pelzel; Cassandra L. Schlamp; Michael Waclawski; Malissa K. Shaw; Robert W. Nickells
TAGS: gene expression, glaucoma, histone deacetylase, mice, retinal ganglion cells, histones, ganglia, optic nerve
Invest. Ophthalmol. Vis. Sci.. 2012; 53(3):1428-1435. doi: https://doi.org/10.1167/iovs.11-8872

Biochemistry and Molecular Biology October 2003

Vitamin D Analogues Increase p53, p21, and Apoptosis in a Xenograft Model of Human Retinoblastoma

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Isabelle Audo; Soesiawati R. Darjatmoko; Cassandra L. Schlamp; Janice M. Lokken; Mary J. Lindstrom; Daniel M. Albert; Robert W. Nickells
TAGS: apoptosis, cell death, neoplasms, retinoblastoma, transplantation, heterologous, vitamin d, in situ nick-end labeling, bromodeoxyuridine, calcitriol, immunohistochemistry
Invest. Ophthalmol. Vis. Sci.. 2003; 44(10):4192-4199. doi: https://doi.org/10.1167/iovs.02-1198

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Online ISSN: 1552-5783

Investigative Ophthalmology & Visual Science
Journal of Vision
Translational Vision Science & Technology

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Copyright © 2015 Association for Research in Vision and Ophthalmology.

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