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Retina September 2018

Three-Dimensional Microscopy Demonstrates Series and Parallel Organization of Human Peripapillary Capillary Plexuses

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Erandi Chandrasekera; Dong An; Ian L. McAllister; Dao-Yi Yu; Chandrakumar Balaratnasingam
TAGS: microcirculation, blood capillaries
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4327-4344. doi: 10.1167/iovs.18-24105

ARVO Annual Meeting Abstract July 2018

Histologically-guided metrics for atrophy progression in age-related macular degeneration (AMD) tested via clinicopathologic correlation.

Rosa Dolz-Marco; Chandrakumar Balaratnasingam; Jerry Messinger; Miaoling Li; K Bailey Freund; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4482. doi:

Glaucoma March 2018

Microvascular Density Is Associated With Retinal Ganglion Cell Axonal Volume in the Laminar Compartments of the Human Optic Nerve Head

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Min H. Kang; Mengchen Suo; Chandrakumar Balaratnasingam; Paula K. Yu; William H. Morgan; Dao-Yi Yu
TAGS: optic disk, retinal ganglion cells, body tissue, eye, cribriform plate, volume, microvessels
Invest. Ophthalmol. Vis. Sci.. 2018; 59(3):1562-1570. doi: 10.1167/iovs.17-23183

Retina January 2018

Quantitative Study of the Macular Microvasculature in Human Donor Eyes

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Paula K. Yu; Zaid Mammo; Chandrakumar Balaratnasingam; Dao-Yi Yu
TAGS: macula lutea, perfusion, diagnostic imaging, eye, macula densa, quantitative research, diameter, donors, microvascular network
Invest. Ophthalmol. Vis. Sci.. 2018; 59(1):108-116. doi: 10.1167/iovs.17-22542

Special Issue August 2017

Activated Retinal Pigment Epithelium, an Optical Coherence Tomography Biomarker for Progression in Age-Related Macular Degeneration

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Christine A. Curcio; Emma C. Zanzottera; Thomas Ach; Chandrakumar Balaratnasingam; K. Bailey Freund
TAGS: drusen, atrophy, biological markers, eye, histology, age-related macular degeneration, optical coherence tomography, retinal pigment epithelium, spectral-domain optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2017; 58(6):BIO211-BIO226. doi: 10.1167/iovs.17-21872

Includes: Multimedia, Supplemental Content

Retina October 2016

Associations Between Retinal Pigment Epithelium and Drusen Volume Changes During the Lifecycle of Large Drusenoid Pigment Epithelial Detachments

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Chandrakumar Balaratnasingam; Lawrence A. Yannuzzi; Christine A. Curcio; William H. Morgan; Giuseppe Querques; Vittorio Capuano; Eric Souied; Jesse Jung; K. Bailey Freund
TAGS: drusen, epithelium, pigment, visual acuity, volume, parents' evaluation of developmental status (pediatric screen), retinal pigment epithelium, parents’ evaluation of developmental status, retinal pigment epithelial detachment, spectral-domain optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2016; 57(13):5479-5489. doi: 10.1167/iovs.16-19816

Retina September 2016

Fractal Dimensional Analysis of Optical Coherence Tomography Angiography in Eyes With Diabetic Retinopathy

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Sarwar Zahid; Rosa Dolz-Marco; K. Bailey Freund; Chandrakumar Balaratnasingam; Kunal Dansingani; Fatimah Gilani; Nitish Mehta; Emma Young; Meredith R. Klifto; Bora Chae; Lawrence A. Yannuzzi; Joshua A. Young
TAGS: angiogram, diabetes mellitus, diabetic retinopathy, fractals, diagnostic imaging, eye, optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2016; 57(11):4940-4947. doi: 10.1167/iovs.16-19656

Articles July 2016

A Comparison Between Optical Coherence Tomography Angiography and Fluorescein Angiography for the Imaging of Type 1 Neovascularization

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Maiko Inoue; Jesse J. Jung; Chandrakumar Balaratnasingam; Kunal K. Dansingani; Elona Dhrami-Gavazi; Mihoko Suzuki; Talisa E. de Carlo; Abtin Shahlaee; Michael A. Klufas; Adil El Maftouhi; Jay S. Duker; Allen C. Ho; Maddalena Quaranta-El Maftouhi; David Sarraf; K. Bailey Freund; for the COFT-1 Study Group
TAGS: angiogram, face, fluorescein angiography, neovascularization, pathologic, diagnostic imaging, eye, optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2016; 57(9):OCT314-OCT323. doi: 10.1167/iovs.15-18900

Retina December 2015

The Spatial Profile of Macular Pigments Is Related to the Topological Characteristics of the Foveal Avascular Zone

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Chandrakumar Balaratnasingam; Bora Chae; Meredith H. Remmer; Erasmo Gomez; Mihoko Suzuki; Michael Engelbert; Richard F. Spaide
TAGS: pigment, macular pigment
Invest. Ophthalmol. Vis. Sci.. 2015; 56(13):7859-7865. doi: 10.1167/iovs.15-17532

Retina August 2015

Quantitative Noninvasive Angiography of the Fovea Centralis Using Speckle Variance Optical Coherence Tomography

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Zaid Mammo; Chandrakumar Balaratnasingam; Paula Yu; Jing Xu; Morgan Heisler; Paul Mackenzie; Andrew Merkur; Andrew Kirker; David Albiani; K. Bailey Freund; Marinko V. Sarunic; Dao-Yi Yu
TAGS: angiogram, fovea centralis, macula lutea, blood capillaries, diagnostic imaging, eye, histology, macula densa, optical coherence tomography, heterogeneity of variance, donors
Invest. Ophthalmol. Vis. Sci.. 2015; 56(9):5074-5086. doi: 10.1167/iovs.15-16773

Retina June 2015

Quantitative Comparison of Retinal Capillary Images Derived By Speckle Variance Optical Coherence Tomography With Histology

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Priscilla Ern Zhi Tan; Chandrakumar Balaratnasingam; Jing Xu; Zaid Mammo; Sherry X. Han; Paul Mackenzie; Andrew W. Kirker; David Albiani; Andrew B. Merkur; Marinko V. Sarunic; Dao-Yi Yu
TAGS: blood capillaries, histology, optical coherence tomography, heterogeneity of variance
Invest. Ophthalmol. Vis. Sci.. 2015; 56(6):3989-3996. doi: 10.1167/iovs.14-15879

Physiology and Pharmacology August 2013

Quantitative Changes in Perifoveal Capillary Networks in Patients With Vascular Comorbidities

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Geoffrey Chan; Chandrakumar Balaratnasingam; Paula K. Yu; William H. Morgan; Ian L. McAllister; Stephen J. Cringle; Dao-Yi Yu
TAGS: comorbidity, blood capillaries, eye
Invest. Ophthalmol. Vis. Sci.. 2013; 54(8):5175-5185. doi: 10.1167/iovs.13-11945

Retina August 2012

Quantitative Confocal Imaging of the Retinal Microvasculature in the Human Retina

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Priscilla Ern Zhi Tan; Paula K. Yu; Chandrakumar Balaratnasingam; Stephen J. Cringle; William H. Morgan; Ian L. McAllister; Dao-Yi Yu
TAGS: blood capillaries, diagnostic imaging, eye, retina, microvascular network, retinal vasculature
Invest. Ophthalmol. Vis. Sci.. 2012; 53(9):5728-5736. doi: 10.1167/iovs.12-10017

Retina August 2012

Quantitative Morphometry of Perifoveal Capillary Networks in the Human Retina

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Geoffrey Chan; Chandrakumar Balaratnasingam; Paula K. Yu; William H. Morgan; Ian L. McAllister; Stephen J. Cringle; Dao-Yi Yu
TAGS: blood capillaries, retina, donors
Invest. Ophthalmol. Vis. Sci.. 2012; 53(9):5502-5514. doi: 10.1167/iovs.12-10265

Letters to the Editor March 2012

Author Response: Morphometric Characteristics of Central Retinal Artery and Vein in the Optic Nerve Head of Patients with Diabetes

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Dao-Yi Yu; Min H. Kang; Chandrakumar Balaratnasingam; Paula K. Yu; William H. Morgan; Ian L. McAllister; Stephen J. Cringle
TAGS: diabetes mellitus, optic disk, central retinal artery
Invest. Ophthalmol. Vis. Sci.. 2012; 53(3):1637-1638. doi: 10.1167/iovs.12-9703

Glaucoma March 2011

Morphometric Characteristics of Central Retinal Artery and Vein Endothelium in the Normal Human Optic Nerve Head

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Min H. Kang; Chandrakumar Balaratnasingam; Paula K. Yu; William H. Morgan; Ian L. McAllister; Stephen J. Cringle; Dao-Yi Yu
TAGS: endothelial cells, endothelium, optic disk, central retinal artery, eye, cribriform plate
Invest. Ophthalmol. Vis. Sci.. 2011; 52(3):1359-1367. doi: 10.1167/iovs.10-6366

Retina December 2010

Microstructure and Network Organization of the Microvasculature in the Human Macula

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Paula K. Yu; Chandrakumar Balaratnasingam; Stephen J. Cringle; Ian L. McAllister; Jan Provis; Dao-Yi Yu
TAGS: arteriole, endothelium, macula lutea, microfilaments, blood capillaries, eye, retina, macula densa, donors, microvascular network
Invest. Ophthalmol. Vis. Sci.. 2010; 51(12):6735-6743. doi: 10.1167/iovs.10-5415

Retina November 2010

Correlation of Histologic and Clinical Images to Determine the Diagnostic Value of Fluorescein Angiography for Studying Retinal Capillary Detail

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Kanishka R. Mendis; Chandrakumar Balaratnasingam; Paula Yu; Chris J. Barry; Ian L. McAllister; Stephen J. Cringle; Dao-Yi Yu
TAGS: fluorescein angiography, blood capillaries
Invest. Ophthalmol. Vis. Sci.. 2010; 51(11):5864-5869. doi: 10.1167/iovs.10-5333

Glaucoma June 2010

Time-Dependent Effects of Focal Retinal Ischemia on Axonal Cytoskeleton Proteins

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Chandrakumar Balaratnasingam; William H. Morgan; Louise Bass; Min Kang; Stephen J. Cringle; Dao-Yi Yu
TAGS: ischemia, retinal ischemia, axon, cytoskeleton, in situ nick-end labeling, optic disk, proteins, retina, did not receive therapy or drug
Invest. Ophthalmol. Vis. Sci.. 2010; 51(6):3019-3028. doi: 10.1167/iovs.09-4692

Retina January 2010

The Structural Relationship between the Microvasculature, Neurons, and Glia in the Human Retina

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Paula K. Yu; Chandrakumar Balaratnasingam; William H. Morgan; Stephen J. Cringle; Ian L. McAllister; Dao-Yi Yu
TAGS: immunohistochemistry, endothelial cells, cadherins, neuroglia, neurons, perfusion, choroid, diagnostic imaging, eye, retina, donors, microvascular network, retinal vasculature
Invest. Ophthalmol. Vis. Sci.. 2010; 51(1):447-458. doi: 10.1167/iovs.09-3978

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Three-Dimensional Microscopy Demonstrates Series and Parallel Organization of Human Peripapillary Capillary Plexuses

Histologically-guided metrics for atrophy progression in age-related macular degeneration (AMD) tested via clinicopathologic correlation.

Microvascular Density Is Associated With Retinal Ganglion Cell Axonal Volume in the Laminar Compartments of the Human Optic Nerve Head

Quantitative Study of the Macular Microvasculature in Human Donor Eyes

Activated Retinal Pigment Epithelium, an Optical Coherence Tomography Biomarker for Progression in Age-Related Macular Degeneration

Associations Between Retinal Pigment Epithelium and Drusen Volume Changes During the Lifecycle of Large Drusenoid Pigment Epithelial Detachments

Fractal Dimensional Analysis of Optical Coherence Tomography Angiography in Eyes With Diabetic Retinopathy

A Comparison Between Optical Coherence Tomography Angiography and Fluorescein Angiography for the Imaging of Type 1 Neovascularization

The Spatial Profile of Macular Pigments Is Related to the Topological Characteristics of the Foveal Avascular Zone

Quantitative Noninvasive Angiography of the Fovea Centralis Using Speckle Variance Optical Coherence Tomography

Quantitative Comparison of Retinal Capillary Images Derived By Speckle Variance Optical Coherence Tomography With Histology

Quantitative Changes in Perifoveal Capillary Networks in Patients With Vascular Comorbidities

Quantitative Confocal Imaging of the Retinal Microvasculature in the Human Retina

Quantitative Morphometry of Perifoveal Capillary Networks in the Human Retina

Author Response: Morphometric Characteristics of Central Retinal Artery and Vein in the Optic Nerve Head of Patients with Diabetes

Morphometric Characteristics of Central Retinal Artery and Vein Endothelium in the Normal Human Optic Nerve Head

Microstructure and Network Organization of the Microvasculature in the Human Macula

Correlation of Histologic and Clinical Images to Determine the Diagnostic Value of Fluorescein Angiography for Studying Retinal Capillary Detail

Time-Dependent Effects of Focal Retinal Ischemia on Axonal Cytoskeleton Proteins

The Structural Relationship between the Microvasculature, Neurons, and Glia in the Human Retina

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