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ARVO Annual Meeting Abstract June 2025

A cross-species comparison of the role of noggin in corneal endothelial health and disease

Sara M Thomasy; Karolina Roszak; Rachel Brady; Julia Malvick; Raneesh Ramarapu; M. Isabel Casanova; Sangwan Park; Xin Gong; Chao Xing; Connor Chang; Allysa Hoehn; Andrew Blandino; Ariana Marangakis; Monica Motta; Michelle Ferneding; Nayeli Echeverria; Monica Ardon; Brian Leonard; Vinod V Mootha; Rebecca Bellone

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2961.

ARVO Annual Meeting Abstract June 2024

Single cell RNA-seq characterization of corneal wound healing following PRK

Katherine Borner; Ze Yu; Chao Xing; Matthew Petroll

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):506.

ARVO Annual Meeting Abstract June 2024

Bi-Allelic TCF4 Trinucleotide Repeat Expansions in Fuchs’ Endothelial Corneal Dystrophy

Danielle Block; Jiaxin Hu; Xin Gong; David Corey; Nick Hogan; Chao Xing; Vinod V Mootha

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5795.

ARVO Annual Meeting Abstract June 2024

Muller glia cell-specific activation of the Ephrin receptor-signaling pathway mediates recovery response in the mouse retina after light injury

Bogale Aredo; Ashwani Kumar; Chao Xing; Bo Chen; Yi Ding; Mark Henkemeyer; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5370.

Retinal Cell Biology August 2023

Single Cell RNA Sequencing Analysis of Mouse Retina Identifies a Subpopulation of Muller Glia Involved in Retinal Recovery From Injury in the FCD-LIRD Model

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Bogale Aredo; Ashwani Kumar; Bo Chen; Chao Xing; Rafael L. Ufret-Vincenty
TAGS: mice, radial retinal glial cell, recovery of function, retina, wounds and injuries, focal cortical dysplasia, gene expression, rna-seq
Invest. Ophthalmol. Vis. Sci.. 2023; 64(11):2. https://doi.org/10.1167/iovs.64.11.2

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Characterization of differential gene expression patterns during corneal fibroblast migration in vivo

Katherine Borner; Chao Xing; Matthew Petroll

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4600.

Cornea April 2023

Mice Deficient in TAZ (Wwtr1) Demonstrate Clinical Features of Late-Onset Fuchs’ Endothelial Corneal Dystrophy

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Brian C. Leonard; Sangwan Park; Soohyun Kim; Laura J. Young; Iman Jalilian; Krista Cosert; Xunzhi Zhang; Jessica M. Skeie; Hanna Shevalye; Nayeli Echeverria; Vanessa Rozo; Xin Gong; Chao Xing; Christopher J. Murphy; Mark A. Greiner; V. Vinod Mootha; Vijay Krishna Raghunathan; Sara M. Thomasy
TAGS: cornea, endothelium, hereditary corneal dystrophy, mice, signs and symptoms, proteins
Invest. Ophthalmol. Vis. Sci.. 2023; 64(4):22. https://doi.org/10.1167/iovs.64.4.22

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Differential response of Muller cells to retinal injury in the fundus camera-delivered light induced retinal degeneration (FCD-LIRD) model

Bogale Aredo; Bo Chen; Yi Ding; Cynthia X. Zhao; Ashwani Kumar; Chao Xing; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1367 – F0298.

ARVO Annual Meeting Abstract June 2021

Analysis of cell type-specific responses to retinal injury in the fundus camera delivered-light induced retinal degeneration (FCD-LIRD) model

Bogale Aredo; Bo Chen; Yi Ding; Cynthia Zhao; Ashwani Kumar; Chao Xing; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3120.

ARVO Annual Meeting Abstract June 2020

Forward genetic analysis combined with OCT and fundus photography identifies mutations leading to progressive outer retinal degeneration in C57BL/6J mice

Bogale Aredo; Bo Chen; Yi Ding; Yuanfei Zhu; Cynthia Zhao; Ashwani Kumar; Chao Xing; Stephen Lyon; Jamie Russell; Xiaohong Li; Miao Tang; Priscilla Anderton; Sara Ludwig; Eva Marie Moresco; Bruce Beutler; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1896.

Cornea August 2018

Instability of TCF4 Triplet Repeat Expansion With Parent–Child Transmission in Fuchs' Endothelial Corneal Dystrophy

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Joanna S. Saade; Chao Xing; Xin Gong; Zhengyang Zhou; V. Vinod Mootha
TAGS: alleles, child, endothelium, hereditary corneal dystrophy, parent, trinucleotide repeats
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):4065-4070. https://doi.org/10.1167/iovs.18-24119

Includes: Supplemental Content

Cornea September 2017

Fuchs' Endothelial Corneal Dystrophy and RNA Foci in Patients With Myotonic Dystrophy

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V. Vinod Mootha; Brock Hansen; Ziye Rong; Pradeep P. Mammen; Zhengyang Zhou; Chao Xing; Xin Gong
TAGS: endothelium, hereditary corneal dystrophy, myotonic dystrophy, rna, trinucleotide repeats, endothelial cells, cornea
Invest. Ophthalmol. Vis. Sci.. 2017; 58(11):4579-4585. https://doi.org/10.1167/iovs.17-22350

Includes: Supplemental Content

Glaucoma May 2016

eNOS Activity in CAV1 Knockout Mouse Eyes

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Yuan Lei; Maomao Song; Jihong Wu; Chao Xing; Xinghuai Sun
TAGS: eye, intraocular pressure, mice, nitric oxide synthase, mice, knockout, donors
Invest. Ophthalmol. Vis. Sci.. 2016; 57(6):2805-2813. https://doi.org/10.1167/iovs.15-18841

Cornea March 2015

TCF4 Triplet Repeat Expansion and Nuclear RNA Foci in Fuchs' Endothelial Corneal Dystrophy

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V. Vinod Mootha; Imran Hussain; Khrishen Cunnusamy; Eric Graham; Xin Gong; Sudha Neelam; Chao Xing; Ralf Kittler; W. Matthew Petroll
TAGS: endothelium, hereditary corneal dystrophy, rna, rna, nuclear, trinucleotide repeats, cornea
Invest. Ophthalmol. Vis. Sci.. 2015; 56(3):2003-2011. https://doi.org/10.1167/iovs.14-16222

Includes: Supplemental Content

Cornea November 2014

Transethnic Replication of Association of CTG18.1 Repeat Expansion of TCF4 Gene With Fuchs' Corneal Dystrophy in Chinese Implies Common Causal Variant

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Chao Xing; Xin Gong; Imran Hussain; Chiea-Chuen Khor; Donald T. H. Tan; Tin Aung; Jodhbir S. Mehta; Eranga N. Vithana; V. Vinod Mootha
TAGS: alleles, chinese (other dialects), chinese people, genes, hereditary corneal dystrophy, polymorphism
Invest. Ophthalmol. Vis. Sci.. 2014; 55(11):7073-7078. https://doi.org/10.1167/iovs.14-15390

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2014

CTG18.1 Trinucleotide Repeat Expansion of TCF4 Gene in Fuchs’ Endothelial Corneal Dystrophy

Ahmed Z Soliman; Xin Gong; Imran Hussain; Chao Xing; Vinod V Mootha

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1005.

Cornea January 2014

Association and Familial Segregation of CTG18.1 Trinucleotide Repeat Expansion of TCF4 Gene in Fuchs' Endothelial Corneal Dystrophy

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V. Vinod Mootha; Xin Gong; Hung-Chih Ku; Chao Xing
TAGS: alleles, endothelium, family, genes, hereditary corneal dystrophy, polymerase chain reaction, trinucleotide repeat expansion, polymorphism, dominant autosomal hereditary disorder with incomplete penetrance, genotype determination
Invest. Ophthalmol. Vis. Sci.. 2014; 55(1):33-42. https://doi.org/10.1167/iovs.13-12611

Includes: Supplemental Content

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A cross-species comparison of the role of noggin in corneal endothelial health and disease

Single cell RNA-seq characterization of corneal wound healing following PRK

Bi-Allelic TCF4 Trinucleotide Repeat Expansions in Fuchs’ Endothelial Corneal Dystrophy

Muller glia cell-specific activation of the Ephrin receptor-signaling pathway mediates recovery response in the mouse retina after light injury

Single Cell RNA Sequencing Analysis of Mouse Retina Identifies a Subpopulation of Muller Glia Involved in Retinal Recovery From Injury in the FCD-LIRD Model

Characterization of differential gene expression patterns during corneal fibroblast migration in vivo

Mice Deficient in TAZ (Wwtr1) Demonstrate Clinical Features of Late-Onset Fuchs’ Endothelial Corneal Dystrophy

Differential response of Muller cells to retinal injury in the fundus camera-delivered light induced retinal degeneration (FCD-LIRD) model

Analysis of cell type-specific responses to retinal injury in the fundus camera delivered-light induced retinal degeneration (FCD-LIRD) model

Forward genetic analysis combined with OCT and fundus photography identifies mutations leading to progressive outer retinal degeneration in C57BL/6J mice

Instability of TCF4 Triplet Repeat Expansion With Parent–Child Transmission in Fuchs' Endothelial Corneal Dystrophy

Fuchs' Endothelial Corneal Dystrophy and RNA Foci in Patients With Myotonic Dystrophy

eNOS Activity in CAV1 Knockout Mouse Eyes

TCF4 Triplet Repeat Expansion and Nuclear RNA Foci in Fuchs' Endothelial Corneal Dystrophy

Transethnic Replication of Association of CTG18.1 Repeat Expansion of TCF4 Gene With Fuchs' Corneal Dystrophy in Chinese Implies Common Causal Variant

CTG18.1 Trinucleotide Repeat Expansion of TCF4 Gene in Fuchs’ Endothelial Corneal Dystrophy

Association and Familial Segregation of CTG18.1 Trinucleotide Repeat Expansion of TCF4 Gene in Fuchs' Endothelial Corneal Dystrophy

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