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Meeting Abstract (26)
Journal Articles (6)

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Investigative Ophthalmology & Visual Science (31)
Translational Vision Science & Technology (1)

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ARVO Annual Meeting Abstract (26)
Immunology and Microbiology (4)
Lens (1)
Special Issue (1)

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Immunology and Microbiology (5)
Eye Anatomy and Disorders (3)
Biochemistry and Molecular Biology (2)
Genetics (2)
Retina (2)
Lens (1)
Visual Neuroscience (1)

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mice (4)
cytokine (2)
proteins (2)
uveitis (2)
animals, transgenic (1)
antibodies (1)
antigens (1)
autoimmune diseases (1)
autoimmunity (1)
body tissue (1)

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ARVO Annual Meeting Abstract June 2024

A Nanobody targeting STAT3 suppresses uveitis and encephalomyelitis by inhibiting pathogenic Th17 cells differentiation

Evaristus C Mbanefo; Manoj Kumar Yadav; Cheng-Rong Yu; Ashutosh Parihar; Singh Sunanda; Charles E Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1448.

ARVO Annual Meeting Abstract June 2024

Interleukin 27 containing exosomes (i27-exosomes) secreted by Retinal Microglia Suppress Uveitis

Manoj Kumar Yadav; Cheng-Rong Yu; Evaristus C Mbanefo; Charles E Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1094.

ARVO Annual Meeting Abstract June 2024

Loss of Interleukin 35 Exacerbates Uveitis and Promotes Persistence of Intraocular Inflammation

Cheng-Rong Yu; Manoj Kumar Yadav; Lijin Dong; Charles E Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5066.

Special Issue December 2020

Identifying Mouse Autoimmune Uveitis from Fundus Photographs Using Deep Learning

PDF

Jian Sun; Xiaoqin Huang; Charles Egwuagu; Youakim Badr; Stephen Charles Dryden; Brian Thomas Fowler; Siamak Yousefi

Trans. Vis. Sci. Tech.. 2020; 9(2):59. https://doi.org/10.1167/tvst.9.2.59

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Loss of interferon regulatory factor 8 (IRF-8) in B cells promotes the expansion of regulatory B cells (Bregs) and suppresses intraocular autoimmune disease

Chengrong Yu; Hyunsu Lee; Daniel Gebreselasssie; Jin Kyeong Choi; Mary Mattapallil; Favour Oladipupop; Charles E Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2544.

ARVO Annual Meeting Abstract July 2018

Interferon Regulatory Factor 8 (IRF8) antagonizes IL-10 and CTLA4 production in T cells

Hyunsu Lee; Chengrong Yu; Charles E Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2545.

ARVO Annual Meeting Abstract July 2018

Therapeutic potential of IL-12p35 Subunit for treatment of uveitis and multiple sclerosis

Jin Kyeong Choi; Chengrong Yu; Anita Uche; Mary J Mattapallil; Favour Oladipupop; Minkyung Kang; Rachel R Caspi; Charles E Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2550.

ARVO Annual Meeting Abstract June 2017

IL-12p35 induces expansion of IL-10- and IL-35-expressing regulatory B cells (Bregs) and ameliorates autoimmune disease

Jin Kyeong Choi; Venkat Mohanram; Chengrong Yu; Anita Uche; Daniel Gebreselassie; Hyunsu lee; Charles Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):543.

ARVO Annual Meeting Abstract June 2017

Human IL35-producing B cells (I35Bregs) are induced by CpG DNA

Chengrong Yu; Charles Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):559.

ARVO Annual Meeting Abstract September 2016

IL-10- and IL-35-expressing cells are highly enriched among peripheral blood B cells during experimental autoimmune uveitis

Chengrong Yu; Rashid M Mahdi; Charles E Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):495.

ARVO Annual Meeting Abstract June 2015

Genetic engineering and characterization of recombinant mouse IL-27 cytokine

Justine Yeung; Lekha Nair; Lin Sun; Charles Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3489.

ARVO Annual Meeting Abstract April 2014

Suppression of experimental autoimmune uveitis (EAU) and recovery from uveitis correlate with expansion of regulatory B cells (Breg)

Chengrong Yu; Ivy M Dambuza; Sung-Hye Kim; Rashid M Mahdi; Charles Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2493.

ARVO Annual Meeting Abstract April 2014

Characterization of the Role of IRF-8 in the Retina During Autoimmune Uveitis

Sung-Hye Kim; Chengrong Yu; Charles Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2503.

ARVO Annual Meeting Abstract June 2013

Osteopontin is Expressed by Microglia and T Cells and Regulated by STAT3

Chengrong Yu; Waynekid Kam; Ivy Dambuza; Bernadette Marrero; Rashid Mahdi; Charles E. Egwuagu; immunology

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2050.

ARVO Annual Meeting Abstract June 2013

IRF-8 Antagonizes Th17 and Tc17 Expansion and Restrains Th17 Inflammatory Responses During Autoimmune Uveitis

Sung-Hye Kim; Chengrong Yu; Bernadette Marrero; Charles E. Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2535.

ARVO Annual Meeting Abstract June 2013

IL-12p35 Inhibits Th1 proliferation and promotes the expansion of Th17 and Treg

Ivy Dambuza; Chengrong Yu; Rashid Mahdi; Renxi Wang; Sung-Hye Kim; Charles E. Egwuagu; Immunology

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):101.

ARVO Annual Meeting Abstract June 2013

STAT3/SOCS3 axis modulates CD8-mediated host immunity against HSV-1

Fatemeh Navid; Chengrong Yu; Ivy Dambuza; Gregory M. Frank; Charles E. Egwuagu; Immunology

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):5989.

Immunology and Microbiology June 2013

STAT3 Activates miR-155 in Th17 Cells and Acts in Concert to Promote Experimental Autoimmune Uveitis

PDF

Thelma Escobar; Cheng-Rong Yu; Stefan A. Muljo; Charles E. Egwuagu
TAGS: autoimmune diseases, autoimmunity, mice, stat3 protein, th17 cells, t-lymphocytes, uveitis
Invest. Ophthalmol. Vis. Sci.. 2013; 54(6):4017-4025. https://doi.org/10.1167/iovs.13-11937

ARVO Annual Meeting Abstract March 2012

IL-27 regulates expression of Complement Factor H in the Retina

Ivy M. Dambuza; Ahjoku Amadi-Obi; Cheng-Rong Yu; Charles E. Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):5274.

ARVO Annual Meeting Abstract March 2012

Temporal Expression of miR-155 Correlates with the initiation and Development of Experimental Autoimmune Uveitis (EAU)

Bernadette Marrero; Yu Chen-Rong; Chandrasekharam Nagineni; Charles Egwuagu

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6238.

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