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Retina November 2024

Diabetes Renders Photoreceptors Susceptible to Retinal Ischemia-Reperfusion Injury

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David A. Antonetti; Cheng-Mao Lin; Sumathi Shanmugam; Heather Hager; Manjing Cao; Xuwen Liu; Alyssa Dreffs; Adam Habash; Steven F. Abcouwer
TAGS: diabetes mellitus, wounds and injuries, mice, retina, photoreceptors, reperfusion injury, streptozocin
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):46. https://doi.org/10.1167/iovs.65.13.46

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Occludin carboxy terminus is a dynein adaptor required for mouse embryonic development

Xuwen Liu; Cheng-Mao Lin; Alyssa Ashleigh Dreffs; Enming Joe Su; Daniel A. Lawrence; David A Antonetti

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):315.

ARVO Annual Meeting Abstract June 2023

Diabetes renders photoreceptors susceptible to ischemia-reperfusion injury

Steven F Abcouwer; Cheng-mao Lin; Heather Hager; Sumathi Shanmugam; Alyssa Dreffs; David A Antonetti

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):993.

ARVO Annual Meeting Abstract June 2023

Norrin prevents visual loss in diabetic rats

Alyssa Dreffs; Cheng-mao Lin; Monica Diaz Coranguez; Sarah Sheskey; David A Antonetti

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):568.

ARVO Annual Meeting Abstract June 2022

Delivery of a hydrophobic small molecule LXR agonist via sHDL nanoparticles in a preclinical model of dry AMD

Eric Weh; Ling Mei; Lisa Walsh; Minzhi Yi; Cheng-mao Lin; Abigail T Fahim; Anna Schwendeman; Cagri Besirli

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):290 – F0093.

Retina August 2021

Correlation of Retinal Structure and Visual Function Assessments in Mouse Diabetes Models

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Sarah R. Sheskey; David A. Antonetti; René C. Rentería; Cheng-Mao Lin
TAGS: diabetes mellitus, diabetes mellitus, type 2, mice, visual acuity, vision, retina, blood glucose
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):20. https://doi.org/10.1167/iovs.62.10.20

Includes: Supplemental Content

Retina June 2020

All- trans -Retinaldehyde Contributes to Retinal Vascular Permeability in Ischemia Reperfusion

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Alyssa Dreffs; Cheng-Mao Lin; Xuwen Liu; Sumathi Shanmugam; Steven F. Abcouwer; Timothy S. Kern; David A. Antonetti
TAGS: endothelial cells, ischemia, mice, permeability, physiologic reperfusion, reperfusion therapy, retinaldehyde, vascular permeability, wounds and injuries, retina
Invest. Ophthalmol. Vis. Sci.. 2020; 61(6):8. https://doi.org/10.1167/iovs.61.6.8

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Effects of diabetes on retinal protein lysine malonylation

Steven F Abcouwer; Sumathi Shanmugam; Heather Hager; Cheng-mao Lin; Thomas W Gardner; Patrice E Fort; Kelli M. Sas; Subramaniam Pennathur

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2678.

ARVO Annual Meeting Abstract July 2019

Endothelial expression of permeability-resistant occludin mutant preserves visual function in diabetes

Cheng-mao Lin; Andreia Goncalves; Jason M Keil; Sarah Sheskey; David A Antonetti

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2692.

ARVO Annual Meeting Abstract July 2018

Disheveled localizes at tight junction sites and interacts with ZO1 in BREC

Monica Diaz-Coranguez; Cheng-mao Lin; David A Antonetti

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4617.

ARVO Annual Meeting Abstract June 2017

Diabetes hinders resolution of inflammation and reestablishment of the inner blood-retinal barrier following retinal ischemia-reperfusion injury

Sumathi Shanmugam; Cheng-mao Lin; Dejuan Kong; Heather Hager; David A Antonetti; Steven F Abcouwer

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2527.

ARVO Annual Meeting Abstract June 2017

Contribution of Th1 and Th17 Cell Responses toward Recoverin Retinal Autoantigen to the Pathogenesis of Autoimmune Retinopathy

Enayat Nikoopour; Cheng-mao Lin; Ray Ohara; John R Heckenlively; Steven K Lundy

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):540.

ARVO Annual Meeting Abstract September 2016

The role of autophagy in catabolism of visual transduction proteins

Jingyu Yao; Lin Jia; Kecia L Feathers; Cheng-mao Lin; Daniel Klionsky; Thomas A Ferguson; David N Zacks

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):185.

ARVO Annual Meeting Abstract September 2016

Onset and resolution of neuroinflammation and inner blood-retinal barrier disruption in a mouse retinal ischemia-reperfusion injury model

Steven F Abcouwer; Arivalagan Muthusamy; Sumathi Shanmugam; Cheng-mao Lin; Heather Hager; Dejuan Kong; David A Antonetti

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12)

ARVO Annual Meeting Abstract September 2016

Vascular endothelial growth factor (VEGF) and bradykinin induce increased electroretinogram amplitude and decreased visual acuity.

Allen C Clermont; Nivetha Murugesan; Cheng-mao Lin; Sarah R Sheskey; David A Antonetti; Edward P Feener

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12)

ARVO Annual Meeting Abstract September 2016

Generation and Phenotyping of P2x7r and Sod1 Double-Knockout Mice

Kyle Carver; Naheed W Khan; Cheng-mao Lin; Dongli Yang

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6546.

Physiology and Pharmacology May 2016

Protective Effect of a GLP-1 Analog on Ischemia-Reperfusion Induced Blood–Retinal Barrier Breakdown and Inflammation

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Andreia Gonçalves; Cheng-Mao Lin; Arivalagan Muthusamy; Carlos Fontes-Ribeiro; António F. Ambrósio; Steven F. Abcouwer; Rosa Fernandes; David A. Antonetti
TAGS: blood-retinal barrier, glucagon-like peptide 1, inflammation, ischemia, microglia, pathophysiology, permeability, physiologic reperfusion, reperfusion therapy, wounds and injuries
Invest. Ophthalmol. Vis. Sci.. 2016; 57(6):2584-2592. https://doi.org/10.1167/iovs.15-19006

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Ischemia-reperfusion injury as a model of activation and resolution of retinal neuroinflammation and vascular permeability

Steven F Abcouwer; Sumathi Shanmugam; Cheng-mao Lin; Heather Lindner; Dolly Ann Padovani-Claudio; Prathiba Jayaguru; Arivalagan Muthusamy; David A Antonetti

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3101.

ARVO Annual Meeting Abstract April 2014

Autophagy in the retinal pigment epithelium: Insights into age-related macular degeneration

Jingyu Yao; Lin Jia; Naheed W Khan; Cheng-mao Lin; Joshua L Dunaief; Michael E Boulton; Daniel Klionsky; Jun-Lin Guan; Debra A Thompson; David N Zacks

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4560.

Retina August 2013

Polychromatic Angiography for the Assessment of VEGF-Induced BRB Dysfunction in the Rabbit Retina

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Samir R. Tari; Maher Youssif; C. Michael Samson; Robert L. Harris; Cheng-Mao Lin; Uday B. Kompella; David A. Antonetti; Gaetano R. Barile
TAGS: angiogram, oryctolagus cuniculus, pathophysiology, retina, vascular endothelial growth factor a, bevacizumab
Invest. Ophthalmol. Vis. Sci.. 2013; 54(8):5550-5558. https://doi.org/10.1167/iovs.13-12144

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Diabetes Renders Photoreceptors Susceptible to Retinal Ischemia-Reperfusion Injury

Occludin carboxy terminus is a dynein adaptor required for mouse embryonic development

Diabetes renders photoreceptors susceptible to ischemia-reperfusion injury

Norrin prevents visual loss in diabetic rats

Delivery of a hydrophobic small molecule LXR agonist via sHDL nanoparticles in a preclinical model of dry AMD

Correlation of Retinal Structure and Visual Function Assessments in Mouse Diabetes Models

All- trans -Retinaldehyde Contributes to Retinal Vascular Permeability in Ischemia Reperfusion

Effects of diabetes on retinal protein lysine malonylation

Endothelial expression of permeability-resistant occludin mutant preserves visual function in diabetes

Disheveled localizes at tight junction sites and interacts with ZO1 in BREC

Diabetes hinders resolution of inflammation and reestablishment of the inner blood-retinal barrier following retinal ischemia-reperfusion injury

Contribution of Th1 and Th17 Cell Responses toward Recoverin Retinal Autoantigen to the Pathogenesis of Autoimmune Retinopathy

The role of autophagy in catabolism of visual transduction proteins

Onset and resolution of neuroinflammation and inner blood-retinal barrier disruption in a mouse retinal ischemia-reperfusion injury model

Vascular endothelial growth factor (VEGF) and bradykinin induce increased electroretinogram amplitude and decreased visual acuity.

Generation and Phenotyping of P2x7r and Sod1 Double-Knockout Mice

Protective Effect of a GLP-1 Analog on Ischemia-Reperfusion Induced Blood–Retinal Barrier Breakdown and Inflammation

Ischemia-reperfusion injury as a model of activation and resolution of retinal neuroinflammation and vascular permeability

Autophagy in the retinal pigment epithelium: Insights into age-related macular degeneration

Polychromatic Angiography for the Assessment of VEGF-Induced BRB Dysfunction in the Rabbit Retina

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