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Journal Articles (4)
Meeting Abstract (4)

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Investigative Ophthalmology & Visual Science (8)

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ARVO Annual Meeting Abstract (4)
Immunology and Microbiology (1)
Retina (1)
Retinal Cell Biology (1)
Visual Psychophysics and Physiological Optics (1)

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Eye Anatomy and Disorders (4)
Retina (4)
Genetics (3)
Immunology and Microbiology (2)
Nanotechnology and Regenerative Medicine (2)
Imaging (1)
Retinal Cell Biology (1)
Retinal Imaging (1)

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eye (3)
gene therapy (2)
retina (2)
retinal neovascularization (2)
vascular endothelial growth factor a (2)
adaptive testing (1)
adenoviruses (1)
blood capillaries (1)
cats (1)
dog, domestic (1)

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ARVO Annual Meeting Abstract July 2018

Subanalysis of data from rAAV.sFLT-1 phase 1 and 2a randomized gene therapy trials for wet age-related macular degeneration.

Elizabeth Rakoczy; Aaron Magno; Chooi-May Lai; Mariapia Degli-Esposti; Ian Constable

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1448. doi:

ARVO Annual Meeting Abstract June 2017

Safety and post hoc analysis of subretinal rAAV.sFLT-1 for wet age-related macular degeneration following a phase 2a randomized clinical trial

Elizabeth P Rakoczy; Chooi-May Lai; Aaron Magno; Martyn French; Steve Butler; Samuel Barone; Steven D Schwartz; Mark Blumenkranz; Mariapia Degli-Esposti; Ian Constable

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4476. doi:

ARVO Annual Meeting Abstract September 2016

Association of serum neutralizing antibodies with safety and efficacy outcomes in a Phase 2a trial of rAAV.sFlt-1 in the treatment of wet AMD

Elizabeth P Rakoczy; Chooi-May Lai; Aaron Magno; Martyn French; Samuel Bradley Barone; Steven D Schwartz; Mark Blumenkranz; Mariapia Degli-Esposti; Ian J Constable

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):526. doi:

ARVO Annual Meeting Abstract June 2015

One-year analysis of sFlt-1 and VEGF proteins and immunological markers in the bodily fluids of subjects participating in the Phase I rAAV.sFlt-1 trial.

Elizabeth P Rakoczy; Chooi-May Lai; Aaron Magno; Matthew Wikstrom; Martyn French; Steven D Schwartz; Mark S Blumenkranz; Thomas Walter Chalberg; Mariapia Degli-Espoti; Ian J Constable

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1281. doi:

Immunology and Microbiology September 2009

rAAV.sFlt-1 Gene Therapy Achieves Lasting Reversal of Retinal Neovascularization in the Absence of a Strong Immune Response to the Viral Vector

PDF

Chooi-May Lai; Marie J. Estcourt; Matthew Wikstrom; Robyn P. Himbeck; Nigel L. Barnett; Meliha Brankov; Lisa B. G. Tee; Sarah A. Dunlop; Mariapia A. Degli-Esposti; Elizabeth P. Rakoczy
TAGS: eye, gene therapy, immune response, mice, retinal neovascularization, viral vector, vascular endothelial growth factor a, proteins
Invest. Ophthalmol. Vis. Sci.. 2009; 50(9):4279-4287. doi: https://doi.org/10.1167/iovs.08-3253

Visual Psychophysics and Physiological Optics October 2006

Early Vascular and Neuronal Changes in a VEGF Transgenic Mouse Model of Retinal Neovascularization

PDF

Pauline E. van Eeden; Lisa B. G. Tee; Sherralee Lukehurst; Chooi-May Lai; Elizabeth P. Rakoczy; Lyn D. Beazley; Sarah A. Dunlop
TAGS: mice, transgenic, retinal neovascularization, vascular endothelial growth factor a, vascular lesions, blood capillaries, retina, rhodopsin
Invest. Ophthalmol. Vis. Sci.. 2006; 47(10):4638-4645. doi: https://doi.org/10.1167/iovs.06-0251

Includes: Multimedia, Supplemental Content

Retina April 2003

Functional and Structural Recovery of the Retina after Gene Therapy in the RPE65 Null Mutation Dog

PDF

Kristina Narfström; Martin L. Katz; Ragnheidur Bragadottir; Mathias Seeliger; Ana Boulanger; T. Michael Redmond; Lynette Caro; Chooi-May Lai; P. Elizabeth Rakoczy
TAGS: dog, domestic, eye, gene therapy, mutation, retina, recovery of function, surgical procedures, operative, electroretinography
Invest. Ophthalmol. Vis. Sci.. 2003; 44(4):1663-1672. doi: https://doi.org/10.1167/iovs.02-0595

Retinal Cell Biology February 2000

The Use of Adenovirus-Mediated Gene Transfer to Develop a Rat Model for Photoreceptor Degeneration

PDF

Chooi-May Lai; Wei-Yong Shen; Ian Constable; Piroska Elizabeth Rakoczy
TAGS: adenoviruses, eye, gene transfer techniques, photoreceptors, tissue degeneration, language morphology, morphology, adaptive testing, cats, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2000; 41(2):580-584. doi:

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Online ISSN: 1552-5783

Investigative Ophthalmology & Visual Science
Journal of Vision
Translational Vision Science & Technology

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Copyright © 2015 Association for Research in Vision and Ophthalmology.

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