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Genetics September 2020

The Role of Chromosome X in Intraocular Pressure Variation and Sex-Specific Effects

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Mark J. Simcoe; Anthony P. Khawaja; Omar A. Mahroo; Christopher J. Hammond; Pirro G. Hysi; for the UK Biobank Eye and Vision Consortium
TAGS: intraocular pressure, open-angle glaucoma, x chromosomes, single nucleotide polymorphism, biobanks, cohort studies
Invest. Ophthalmol. Vis. Sci.. 2020; 61(11):20. doi: https://doi.org/10.1167/iovs.61.11.20

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

A multiomics investigation of risk factors associated with intraocular pressure in the general population

Pirro G Hysi; Anthony P Khawaja; Christopher Hammond

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):979. doi:

ARVO Annual Meeting Abstract June 2020

Iris reflectance measurements in >1000 healthy adult twins: exploration of heritability and associations with eye color

Andrea Kimberly Uy; Xiaofan Jiang; Alex Tanner; Mark Simcoe; Diana Kozareva; Katie Williams; Pirro G Hysi; Christopher Hammond; Omar Abdul Rahman Mahroo

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1866. doi:

ARVO Annual Meeting Abstract June 2020

A large cross-ancestry meta-analysis of genome-wide association studies identifies 69 novel risk loci for primary open-angle glaucoma, and shows a genetic link to Alzheimer’s disease.

Janey Wiggs; Puya Gharahkhani; Eric Jorgenson; Pirro G Hysi; Anthony Khawaja; Sarah Pendergrass; Xikun Han; David Mackey; Christopher Hammond; Michael A Hauser; Louis R Pasquale; Caroline Klaver; Michiaki Kubo; Tin Aung; Jamie E Craig; Stuart MacGregor

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1890. doi:

ARVO Annual Meeting Abstract June 2020

Exploring rod system dysfunction in patients with CRX -associated retinopathy

Rola Ba-Abbad; Shaun Leo; Xiaofan Jiang; Isabelle Chow; Mathura Indusegaran; Christopher Hammond; Michel Michaelides; Andrew R. Webster; Anthony G Robson; Omar Abdul Rahman Mahroo

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3989. doi:

ARVO Annual Meeting Abstract June 2020

Electrophysiological Assessment in Birdshot Chorioretinopathy: Use of a Portable Device in the Clinic

Anna Michelle Waldie; Angharad E Hobby; Isabelle Chow; Elisa Eleanor Cornish; Mathura Indusegaran; Alexandra Pekacka; Vuong Nguyen; Clare Fraser; Alison M Binns; Miles R. Stanford; Christopher Hammond; Peter J McCluskey; John R Grigg; Omar Mahroo

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5045. doi:

ARVO Annual Meeting Abstract June 2020

Diminished light adaptation effect seen in cone-driven responses in GRK1 -associated Oguchi disease: evidence for possible rod input to cone adaptation pathways

ZIHE XU; Xiaofan Jiang; James Bellingham; Zakariya Jarrar; Christopher Hammond; Andrew R. Webster; Nigel Davies; Moin Mohamed; Gavin Arno; Pirro G Hysi; Omar Abdul Rahman Mahroo

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5052. doi:

ARVO Annual Meeting Abstract June 2020

Tracking Slowed Dark Adaptation Dynamically in Vitamin A deficiency and retinal disease by electroretinogram

Xiaofan Jiang; Shaun Leo; Isabelle Chow; Mathura Indusegaran; Anthony G Robson; Andrew R. Webster; Christopher Hammond; Omar Abdul Rahman Mahroo

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5053. doi:

Retina May 2020

Segmented Macular Layer Volumes from Spectral Domain Optical Coherence Tomography in 184 Adult Twins: Associations With Age and Heritability

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Ali Lamin; Zakariya Jarrar; Katie M. Williams; Anurag Garg; Khadijah Basheer; Sobha Sivaprasad; Christopher J. Hammond; Omar A. Mahroo
TAGS: adult, cohort studies, spectral domain-optical coherence tomography, twins, volume
Invest. Ophthalmol. Vis. Sci.. 2020; 61(5):44. doi: https://doi.org/10.1167/iovs.61.5.44

ARVO Annual Meeting Abstract July 2019

Gene-drug interactions alter response to prostaglandin analogue treatment of high intraocular pressure and glaucoma

Pirro G Hysi; Mark James Simcoe; Anthony P Khawaja; Christopher J Hammond

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5223. doi:

ARVO Annual Meeting Abstract July 2019

Effect of the age of myopia onset, environmental factors and genetic risk on myopia in the CREAM Consortium

Katie Williams; Pirro G Hysi; Sonoko Sensaki; Willem Tideman; Seyhan Yazar; juho wedenoja; Mingguang He; Olavi Parssinen; David A Mackey; Caroline C W Klaver; Christopher J Hammond; Seang-Mei Saw

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5226. doi:

ARVO Annual Meeting Abstract July 2019

GWAS of corneal biomechanics identifies over 200 novel associated loci providing additional insight into the genetic aetiology of ocular disease

Mark James Simcoe; Anthony P Khawaja; Christopher J Hammond; Pirro G Hysi

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5227. doi:

ARVO Annual Meeting Abstract July 2019

The use of analgesics associated with refractive error shift toward hypermetropia

Karina Patasova; Pirro G Hysi; Christopher J Hammond; Robert Wojciechowski

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5844. doi:

ARVO Annual Meeting Abstract July 2019

Rapid non-mydriatic assessment of panretinal cone system function using a hand-held electroretinography device in ABCA4 retinopathy

diana-maria butu; Ana Fakin; Talha Soorma; April Q Neville; Christopher J Hammond; Michel Michaelides; Andrew Webster; Omar Abdul Rahman Mahroo

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5952. doi:

ARVO Annual Meeting Abstract July 2019

Big Data -Omics: Approaches for Genetics and Biological Research

Christopher J Hammond

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):15. doi:

ARVO Annual Meeting Abstract July 2019

Analysing the gut microbiome in relation to early age-related maculopathy (ARM) in a twin cohort.

Zakariya Jarrar; Adewale Adebayo; Ruth Bowyer; Philippa Wells; Katie Williams; Claire Steves; Christopher J Hammond

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1142. doi:

ARVO Annual Meeting Abstract July 2019

Cascade Screening Study of African-Caribbean patients with glaucoma

Sam Myers; Mark James Simcoe; Diana Kozareva; Christopher J Hammond

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1995. doi:

ARVO Annual Meeting Abstract July 2019

The incidence of negative electroretinograms in a healthy adult cohort

Talib Dar; Isabelle Chow; Xiaofan Jiang; Taha Bhatti; Ambreen Tariq; Katie Williams; Pirro G Hysi; Christopher J Hammond; Omar Abdul Rahman Mahroo

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2497. doi:

ARVO Annual Meeting Abstract July 2019

The double trough a-wave response in the DA 3.0 electroretinogram: possible contributions from cone-driven pathways

Mohamed Saad Mohamed Rashad; Mathura Indusegaran; Xiaofan Jiang; Isabelle Chow; ZIHE XU; Moin Mohamed; Christopher J Hammond; Omar Abdul Rahman Mahroo

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2500. doi:

ARVO Annual Meeting Abstract July 2019

Light adaptation of the photopic electroretinogram in healthy subjects, and in patients with diseases affecting ganglion cells, the retinal pigment epithelium and the rod system

ZIHE XU; Xiaofan Jiang; Isabelle Chow; Mathura Indusegaran; Zainab Saleem; Gordon T Plant; Andrew Webster; Christopher J Hammond; Omar Abdul Rahman Mahroo

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2501. doi:

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The Role of Chromosome X in Intraocular Pressure Variation and Sex-Specific Effects

A multiomics investigation of risk factors associated with intraocular pressure in the general population

Iris reflectance measurements in >1000 healthy adult twins: exploration of heritability and associations with eye color

A large cross-ancestry meta-analysis of genome-wide association studies identifies 69 novel risk loci for primary open-angle glaucoma, and shows a genetic link to Alzheimer’s disease.

Exploring rod system dysfunction in patients with CRX -associated retinopathy

Electrophysiological Assessment in Birdshot Chorioretinopathy: Use of a Portable Device in the Clinic

Diminished light adaptation effect seen in cone-driven responses in GRK1 -associated Oguchi disease: evidence for possible rod input to cone adaptation pathways

Tracking Slowed Dark Adaptation Dynamically in Vitamin A deficiency and retinal disease by electroretinogram

Segmented Macular Layer Volumes from Spectral Domain Optical Coherence Tomography in 184 Adult Twins: Associations With Age and Heritability

Gene-drug interactions alter response to prostaglandin analogue treatment of high intraocular pressure and glaucoma

Effect of the age of myopia onset, environmental factors and genetic risk on myopia in the CREAM Consortium

GWAS of corneal biomechanics identifies over 200 novel associated loci providing additional insight into the genetic aetiology of ocular disease

The use of analgesics associated with refractive error shift toward hypermetropia

Rapid non-mydriatic assessment of panretinal cone system function using a hand-held electroretinography device in ABCA4 retinopathy

Big Data -Omics: Approaches for Genetics and Biological Research

Analysing the gut microbiome in relation to early age-related maculopathy (ARM) in a twin cohort.

Cascade Screening Study of African-Caribbean patients with glaucoma

The incidence of negative electroretinograms in a healthy adult cohort

The double trough a-wave response in the DA 3.0 electroretinogram: possible contributions from cone-driven pathways

Light adaptation of the photopic electroretinogram in healthy subjects, and in patients with diseases affecting ganglion cells, the retinal pigment epithelium and the rod system

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