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Special Issue February 2019

IMI – Myopia Genetics Report

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Milly S. Tedja; Annechien E. G. Haarman; Magda A. Meester-Smoor; Jaakko Kaprio; David A. Mackey; Jeremy A. Guggenheim; Christopher J. Hammond; Virginie J. M. Verhoeven; Caroline C. W. Klaver; for the CREAM Consortium
TAGS: genes, myopia, refractive errors, genetics, genome-wide association study, universities
Invest. Ophthalmol. Vis. Sci.. 2019; 60(3):M89-M105. doi: 10.1167/iovs.18-25965

ARVO Annual Meeting Abstract July 2018

Analyses of the UK Biobank data highlights hundreds of genetic loci and pathways associated with refractive error and myopia

Christopher J Hammond; Pirro G Hysi; Anthony Khawaja; Paul J Foster; Phillippa Cumberland; Peng Tee Khaw; Jugnoo Rahi

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):775. doi:

ARVO Annual Meeting Abstract July 2018

Circulating O-methylascorbate is associated with population IOP variation: a metabolomics and GWAS study

Pirro G Hysi; Tim Spector; Christopher J Hammond

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):777. doi:

ARVO Annual Meeting Abstract July 2018

GWAS identifies 52 genomic regions associated with iris colour in a study conducted using almost 200,000 participants of European descent

Mark James Simcoe; Manfred Kayser; Tim Spector; Christopher J Hammond; Pirro G Hysi

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):781. doi:

ARVO Annual Meeting Abstract July 2018

Genome-wide association study of intraocular pressure identifies 83 novel loci

Anthony P Khawaja; Jessica Cooke Bailey; Mark James Simcoe; Robert P Igo; Louis R. Pasquale; Paul J Foster; Janey L Wiggs; Christopher J Hammond; Pirro G Hysi

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1178. doi:

ARVO Annual Meeting Abstract July 2018

Does retinal neuronal processing slow with age? Photopic flicker electroretinograms from over 700 unrelated individuals

Omar Abdul Rahman Mahroo; Diana Kozareva; Talha Soorma; Alexander M Tanner; Ammar Yusuf; Haya Al-Ani; Christopher J Hammond

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1261. doi:

ARVO Annual Meeting Abstract July 2018

Post-GWAS analysis on the molecular machinery in refractive error development

Milly S. Tedja; Robert Wojciechowski; Pirro G Hysi; Virginie JM Verhoeven; Christopher J Hammond; Caroline C W Klaver

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1821. doi:

ARVO Annual Meeting Abstract July 2018

Assessment of shared heritability between spherical equivalent and the age of the first spectacle wear in UK Biobank cohort

Karina Patasova; Pirro G Hysi; Christopher J Hammond; Robert Wojciechowski; Phillippa Cumberland; Anthony P Khawaja; Jugnoo Rahi

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1826. doi:

ARVO Annual Meeting Abstract July 2018

A GWAS investigation of dry eye disease in two European populations

Jelle Vehof; Christopher J Hammond; Pirro G Hysi

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1962. doi:

ARVO Annual Meeting Abstract July 2018

The relationship between occupation and dry eye disease

Shehnaz Bazeer; Laura Wolpert; Christopher J Hammond; Jelle Vehof

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1964. doi:

ARVO Annual Meeting Abstract July 2018

Investigating the relationship between retinal nerve fibre layer thickness and intraocular pressure in an aging twin population

Claire Lixian Wong; Mark James Simcoe; Diana Kozareva; Christopher J Hammond

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2696. doi:

ARVO Annual Meeting Abstract July 2018

Quantifying the proportion of normal eyes deviating from the “ISNT” rule using OCT measurement of peripapillary retinal nerve fibre layer thickness in a healthy cohort

Zakariya Jarrar; Khadijah Basheer; Anurag Garg; Christopher J Hammond; Omar Abdul Rahman Mahroo

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4073. doi:

ARVO Annual Meeting Abstract July 2018

Genome-wide association study of primary open-angle glaucoma in continental and admixed African populations.

Pieter W.M. Bonnemaijer; Adriana I Iglesias; Anna Sanyiwa; Hassan G Hassan; Heiko Philippin; Colin Cook; Janey L Wiggs; Christopher J Hammond; Michael A Hauser; Hans G Lemij; Ruth Loos; Cornelia van Duijn; Alberta A H J Thiadens; Caroline C W Klaver

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5136. doi:

ARVO Annual Meeting Abstract July 2018

Identifying discordant twins for glaucoma using self-report

Sam Myers; Mark James Simcoe; Jelle Vehof; Christopher J Hammond

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5154. doi:

ARVO Annual Meeting Abstract July 2018

A hypothesis-free study of medication use and symptomatic dry eye in 79,866 participants

Laura Wolpert; Shehnaz Bazeer; Christopher J Hammond; Jelle Vehof

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):958. doi:

Genetics May 2018

Family-Based Genome-Wide Association Study of South Indian Pedigrees Supports WNT7B as a Central Corneal Thickness Locus

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Bao Jian Fan; Xueli Chen; Nisha Sondhi; P. Ferdinamarie Sharmila; Nagasamy Soumittra; Sarangapani Sripriya; Srinivasan Sacikala; Rashima Asokan; David S. Friedman; Louis R. Pasquale; X. Raymond Gao; Lingam Vijaya; Jessica Cooke Bailey; Veronique Vitart; Stuart MacGregor; Christopher J. Hammond; Chiea Chuen Khor; Jonathan L. Haines; Ronnie George; Janey L. Wiggs; for the Mexican American Glaucoma Genetic Study; International Glaucoma Genetics Consortium; and NEIGHBORHOOD Consortium
TAGS: cohort studies, family, genetic pedigree, single nucleotide polymorphism, cornea, genome-wide association study
Invest. Ophthalmol. Vis. Sci.. 2018; 59(6):2495-2502. doi: 10.1167/iovs.17-23536

Includes: Supplemental Content

Glaucoma June 2017

Genetic African Ancestry Is Associated With Central Corneal Thickness and Intraocular Pressure in Primary Open-Angle Glaucoma

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Pieter W. M. Bonnemaijer; Colin Cook; Abhishek Nag; Christopher J. Hammond; Cornelia M. van Duijn; Hans G. Lemij; Caroline C. W. Klaver; Alberta A. H. J. Thiadens
TAGS: open-angle glaucoma, cornea, genetics, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3172-3180. doi: 10.1167/iovs.17-21716

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Towards elucidation of the myopia signalling cascade: association of human cone system electrophysiological response parameters with a myopia susceptibility polymorphism

Omar Abdul Rahman Mahroo; Ambreen Tariq; Taha Bhatti; Ting Shen; Katie M Williams; Christopher J Hammond; Pirro G Hysi

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1097. doi:

ARVO Annual Meeting Abstract June 2017

Light processing and regulators are important mechanisms in refractive error

Milly S. Tedja; Robert Wojciechowski; Pirro G Hysi; Virginie JM Verhoeven; Adriana I Iglesias; Roxanna Haak; Peter J Van der Spek; Christopher J Hammond; Caroline Klaver

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1225. doi:

ARVO Annual Meeting Abstract June 2017

Post-GWAS analysis approaches uncover dozens of novel genes associated with myopic refractive error

Stuart MacGregor; Milly S. Tedja; Robert Wojciechowski; Pirro G Hysi; Virginie JM Verhoeven; Christopher J Hammond; Adriana I Iglesias; David A Mackey; Cornelia van Duijn; Caroline Klaver

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1226. doi:

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IMI – Myopia Genetics Report

Analyses of the UK Biobank data highlights hundreds of genetic loci and pathways associated with refractive error and myopia

Circulating O-methylascorbate is associated with population IOP variation: a metabolomics and GWAS study

GWAS identifies 52 genomic regions associated with iris colour in a study conducted using almost 200,000 participants of European descent

Genome-wide association study of intraocular pressure identifies 83 novel loci

Does retinal neuronal processing slow with age? Photopic flicker electroretinograms from over 700 unrelated individuals

Post-GWAS analysis on the molecular machinery in refractive error development

Assessment of shared heritability between spherical equivalent and the age of the first spectacle wear in UK Biobank cohort

A GWAS investigation of dry eye disease in two European populations

The relationship between occupation and dry eye disease

Investigating the relationship between retinal nerve fibre layer thickness and intraocular pressure in an aging twin population

Quantifying the proportion of normal eyes deviating from the “ISNT” rule using OCT measurement of peripapillary retinal nerve fibre layer thickness in a healthy cohort

Genome-wide association study of primary open-angle glaucoma in continental and admixed African populations.

Identifying discordant twins for glaucoma using self-report

A hypothesis-free study of medication use and symptomatic dry eye in 79,866 participants

Family-Based Genome-Wide Association Study of South Indian Pedigrees Supports WNT7B as a Central Corneal Thickness Locus

Genetic African Ancestry Is Associated With Central Corneal Thickness and Intraocular Pressure in Primary Open-Angle Glaucoma

Towards elucidation of the myopia signalling cascade: association of human cone system electrophysiological response parameters with a myopia susceptibility polymorphism

Light processing and regulators are important mechanisms in refractive error

Post-GWAS analysis approaches uncover dozens of novel genes associated with myopic refractive error

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