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Genetics September 2020

The Role of Chromosome X in Intraocular Pressure Variation and Sex-Specific Effects

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Mark J. Simcoe; Anthony P. Khawaja; Omar A. Mahroo; Christopher J. Hammond; Pirro G. Hysi; for the UK Biobank Eye and Vision Consortium
TAGS: intraocular pressure, open-angle glaucoma, x chromosomes, single nucleotide polymorphism, biobanks, cohort studies
Invest. Ophthalmol. Vis. Sci.. 2020; 61(11):20. doi: https://doi.org/10.1167/iovs.61.11.20

Includes: Supplemental Content

Retina May 2020

Segmented Macular Layer Volumes from Spectral Domain Optical Coherence Tomography in 184 Adult Twins: Associations With Age and Heritability

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Ali Lamin; Zakariya Jarrar; Katie M. Williams; Anurag Garg; Khadijah Basheer; Sobha Sivaprasad; Christopher J. Hammond; Omar A. Mahroo
TAGS: adult, cohort studies, spectral domain-optical coherence tomography, twins, volume
Invest. Ophthalmol. Vis. Sci.. 2020; 61(5):44. doi: https://doi.org/10.1167/iovs.61.5.44

ARVO Annual Meeting Abstract July 2019

Gene-drug interactions alter response to prostaglandin analogue treatment of high intraocular pressure and glaucoma

Pirro G Hysi; Mark James Simcoe; Anthony P Khawaja; Christopher J Hammond

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5223. doi:

ARVO Annual Meeting Abstract July 2019

Effect of the age of myopia onset, environmental factors and genetic risk on myopia in the CREAM Consortium

Katie Williams; Pirro G Hysi; Sonoko Sensaki; Willem Tideman; Seyhan Yazar; juho wedenoja; Mingguang He; Olavi Parssinen; David A Mackey; Caroline C W Klaver; Christopher J Hammond; Seang-Mei Saw

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5226. doi:

ARVO Annual Meeting Abstract July 2019

GWAS of corneal biomechanics identifies over 200 novel associated loci providing additional insight into the genetic aetiology of ocular disease

Mark James Simcoe; Anthony P Khawaja; Christopher J Hammond; Pirro G Hysi

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5227. doi:

ARVO Annual Meeting Abstract July 2019

The use of analgesics associated with refractive error shift toward hypermetropia

Karina Patasova; Pirro G Hysi; Christopher J Hammond; Robert Wojciechowski

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5844. doi:

ARVO Annual Meeting Abstract July 2019

Rapid non-mydriatic assessment of panretinal cone system function using a hand-held electroretinography device in ABCA4 retinopathy

diana-maria butu; Ana Fakin; Talha Soorma; April Q Neville; Christopher J Hammond; Michel Michaelides; Andrew Webster; Omar Abdul Rahman Mahroo

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5952. doi:

ARVO Annual Meeting Abstract July 2019

Big Data -Omics: Approaches for Genetics and Biological Research

Christopher J Hammond

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):15. doi:

ARVO Annual Meeting Abstract July 2019

Analysing the gut microbiome in relation to early age-related maculopathy (ARM) in a twin cohort.

Zakariya Jarrar; Adewale Adebayo; Ruth Bowyer; Philippa Wells; Katie Williams; Claire Steves; Christopher J Hammond

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1142. doi:

ARVO Annual Meeting Abstract July 2019

Cascade Screening Study of African-Caribbean patients with glaucoma

Sam Myers; Mark James Simcoe; Diana Kozareva; Christopher J Hammond

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1995. doi:

ARVO Annual Meeting Abstract July 2019

The incidence of negative electroretinograms in a healthy adult cohort

Talib Dar; Isabelle Chow; Xiaofan Jiang; Taha Bhatti; Ambreen Tariq; Katie Williams; Pirro G Hysi; Christopher J Hammond; Omar Abdul Rahman Mahroo

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2497. doi:

ARVO Annual Meeting Abstract July 2019

The double trough a-wave response in the DA 3.0 electroretinogram: possible contributions from cone-driven pathways

Mohamed Saad Mohamed Rashad; Mathura Indusegaran; Xiaofan Jiang; Isabelle Chow; ZIHE XU; Moin Mohamed; Christopher J Hammond; Omar Abdul Rahman Mahroo

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2500. doi:

ARVO Annual Meeting Abstract July 2019

Light adaptation of the photopic electroretinogram in healthy subjects, and in patients with diseases affecting ganglion cells, the retinal pigment epithelium and the rod system

ZIHE XU; Xiaofan Jiang; Isabelle Chow; Mathura Indusegaran; Zainab Saleem; Gordon T Plant; Andrew Webster; Christopher J Hammond; Omar Abdul Rahman Mahroo

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2501. doi:

ARVO Annual Meeting Abstract July 2019

Genome-wide association study of macular ganglion cell complex thickness in 41,504 participants of the UK Biobank study

Hannah Currant; Tomas Fitzgerald; Pirro G Hysi; Charles A Reisman; Qi Yang; Christopher J Hammond; Peng Tee Khaw; Paul J Foster; Praveen Patel; Ewan Birney; Anthony P Khawaja

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2830. doi:

ARVO Annual Meeting Abstract July 2019

Dark-adapted rod and cone system responses in a genotyped twin cohort: exploring heritability and associations with a myopia risk variant

Xiaofan Jiang; Isabelle Chow; Ambreen Tariq; Taha Bhatti; Talha Soorma; Katie Williams; Christopher J Hammond; Omar Abdul Rahman Mahroo

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3144. doi:

ARVO Annual Meeting Abstract July 2019

Genome-wide association study on a large multi-ethnic sample identifies new genetic loci that predispose to keratoconus

Alison J Hardcastle; Pirro G Hysi; Karla Rojas-Lopez; Petra Liskova; Alice E Davidson; Manir Ali; Kathryn P Burdon; David O'Brart; Chris Inglehearn; Paul N Baird; Christopher J Hammond; Stephen J Tuft

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4249. doi:

ARVO Annual Meeting Abstract July 2019

Integrative analysis of GWAS and eQTLs proposes new genetic associations and causal genes for Primary Open Angle Glaucoma

Ayellet Segre; Andrew Hamel; John Rouhana; Anthony P Khawaja; Mark James Simcoe; Christopher J Hammond; Pirro G Hysi; GTEx consortium; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4252. doi:

ARVO Annual Meeting Abstract July 2019

The relationship between personality and eye disorders: from neuroticism in dry eye to excitement-seeking and invulnerability in refractive surgery patients

Jelle Vehof; Christopher J Hammond

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4461. doi:

Special Issue February 2019

IMI – Myopia Genetics Report

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Milly S. Tedja; Annechien E. G. Haarman; Magda A. Meester-Smoor; Jaakko Kaprio; David A. Mackey; Jeremy A. Guggenheim; Christopher J. Hammond; Virginie J. M. Verhoeven; Caroline C. W. Klaver; for the CREAM Consortium
TAGS: genetics, myopia, genome-wide association study, universities, refractive errors, genes
Invest. Ophthalmol. Vis. Sci.. 2019; 60(3):M89-M105. doi: https://doi.org/10.1167/iovs.18-25965

ARVO Annual Meeting Abstract July 2018

A hypothesis-free study of medication use and symptomatic dry eye in 79,866 participants

Laura Wolpert; Shehnaz Bazeer; Christopher J Hammond; Jelle Vehof

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):958. doi:

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The Role of Chromosome X in Intraocular Pressure Variation and Sex-Specific Effects

Segmented Macular Layer Volumes from Spectral Domain Optical Coherence Tomography in 184 Adult Twins: Associations With Age and Heritability

Gene-drug interactions alter response to prostaglandin analogue treatment of high intraocular pressure and glaucoma

Effect of the age of myopia onset, environmental factors and genetic risk on myopia in the CREAM Consortium

GWAS of corneal biomechanics identifies over 200 novel associated loci providing additional insight into the genetic aetiology of ocular disease

The use of analgesics associated with refractive error shift toward hypermetropia

Rapid non-mydriatic assessment of panretinal cone system function using a hand-held electroretinography device in ABCA4 retinopathy

Big Data -Omics: Approaches for Genetics and Biological Research

Analysing the gut microbiome in relation to early age-related maculopathy (ARM) in a twin cohort.

Cascade Screening Study of African-Caribbean patients with glaucoma

The incidence of negative electroretinograms in a healthy adult cohort

The double trough a-wave response in the DA 3.0 electroretinogram: possible contributions from cone-driven pathways

Light adaptation of the photopic electroretinogram in healthy subjects, and in patients with diseases affecting ganglion cells, the retinal pigment epithelium and the rod system

Genome-wide association study of macular ganglion cell complex thickness in 41,504 participants of the UK Biobank study

Dark-adapted rod and cone system responses in a genotyped twin cohort: exploring heritability and associations with a myopia risk variant

Genome-wide association study on a large multi-ethnic sample identifies new genetic loci that predispose to keratoconus

Integrative analysis of GWAS and eQTLs proposes new genetic associations and causal genes for Primary Open Angle Glaucoma

The relationship between personality and eye disorders: from neuroticism in dry eye to excitement-seeking and invulnerability in refractive surgery patients

IMI – Myopia Genetics Report

A hypothesis-free study of medication use and symptomatic dry eye in 79,866 participants

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