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Glaucoma October 2022

Optic Nerve Head Myelin-Related Protein, GFAP, and Iba1 Alterations in Non-Human Primates With Early to Moderate Experimental Glaucoma

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Priya Chaudhary; Cheri Stowell; Juan Reynaud; Stuart K. Gardiner; Hongli Yang; Galen Williams; Imee Williams; Nicholas Marsh-Armstrong; Claude F. Burgoyne
TAGS: eye, glaucoma, glial fibrillary acidic protein, myelin, optic disk, pixel, proteins, optic nerve, primates, paraffin
Invest. Ophthalmol. Vis. Sci.. 2022; 63(11):9. doi: https://doi.org/10.1167/iovs.63.11.9

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Decreased retrolaminar Myelin protein expression in Non-Human Primate (NHP) Early Experimental Glaucoma (EG) is accompanied by increased Iba1(+) cell counts and decreased GFAP signal intensity

Priya Chaudhary; Cheri Stowell; Juan Reynaud; Stuart Keith Gardiner; Galen Williams; Imee Williams; Nicholas Marsh-Armstrong; Claude F Burgoyne

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):933 – A0402. doi:

ARVO Annual Meeting Abstract June 2022

Correlating longitudinal Optical Coherence Tomography (OCT) structural change to retrolaminar myelin-related protein alteration in non-human primate (NHP) early experimental glaucoma (EG)

Hongli Yang; Priya Chaudhary; Cheri Stowell; Juan Reynaud; Stuart Keith Gardiner; Galen Williams; Imee Williams; Nicholas Marsh-Armstrong; Claude F Burgoyne

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3095. doi:

ARVO Annual Meeting Abstract June 2021

Diagnostic accuracy of inner retinal layer thickness and reflectance intensity measurements assessed in posterior pole OCT scans of healthy and glaucomatous eyes

Hongli Yang; Juan Reynaud; Glen P Sharpe; Dawn Jennings; Cindy Albert; Galen Williams; Xiue Jiang; Shaban Demirel; Steven L Mansberger; Jayme R Vianna; Marcelo Nicolela; Balwantray C Chauhan; Claude F Burgoyne; Stuart Keith Gardiner; Brad Fortune

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1836. doi:

ARVO Annual Meeting Abstract June 2021

Optic Nerve Head Cavernous Voids in Glaucoma Suspect and Glaucoma Patients

Bennett Hong; Robert Kinast; Brad Fortune; Claude F Burgoyne; Steven L Mansberger

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3394. doi:

ARVO Annual Meeting Abstract June 2020

Diagnostic accuracy of individual and combined retinal layer thickness measurements assessed at each pixel within posterior pole OCT scans of healthy and glaucomatous eyes

Hongli Yang; Juan Reynaud; Glen P Sharpe; Dawn Jennings; Cindy Albert; Galen Williams; Xiue Jiang; Shaban Demirel; Steven L Mansberger; Jayme R Vianna; Marcelo T Nicolela; Stuart Keith Gardiner; Balwantray C Chauhan; Claude F Burgoyne; Brad Fortune

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3935. doi:

ARVO Annual Meeting Abstract June 2020

Asymmetry of Peripapillary Retinal Blood Vessel Position and Thickness in Healthy Right and Left Eyes

Jack Quach; Glen P Sharpe; Shaban Demirel; Christopher A Girkin; Christian Y Mardin; Alexander Friedrich Scheuerle; Claude F Burgoyne; Balwantray C Chauhan; Jayme R Vianna

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3918. doi:

ARVO Annual Meeting Abstract June 2020

Novel Eye Drop Delivery Aid Preferred Over Traditional Eye Drop Delivery

Facundo Gregorio Sanchez; Steven L Mansberger; Yungtai Kung; Stuart Keith Gardiner; Claude F Burgoyne; Emily P Jones; Robert M Kinast

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2663. doi:

ARVO Annual Meeting Abstract June 2020

Does loss of vasculature contribute to early stage glaucomatous thinning of the retinal nerve fiber layer (RNFL)?

Brad Fortune; Juan Reynaud; Christy Hardin; Laura J Wilsey; Taylor Sund; Stuart Keith Gardiner; Claude F Burgoyne

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3531. doi:

ARVO Annual Meeting Abstract June 2020

Comparison of glaucoma diagnostic OCT parameters derived directly from circumpapillary and radial B-scans versus from raster grid scans

Christy Hardin; Juan Reynaud; Laura J Wilsey; Taylor Sund; Stuart Keith Gardiner; Claude F Burgoyne; Brad Fortune

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4792. doi:

Glaucoma October 2019

The Relationship Between Scleral Strain Change and Differential Cumulative Intraocular Pressure Exposure in the Nonhuman Primate Chronic Ocular Hypertension Model

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Massimo A. Fazio; Michael J. A. Girard; Wonyul Lee; Jeffrey S. Morris; Claude F. Burgoyne; J. Crawford Downs
TAGS: eye, intraocular pressure, ocular hypertension, sclera, primates
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4141-4150. doi: https://doi.org/10.1167/iovs.19-27060

ARVO Annual Meeting Abstract July 2019

Anterior Scleral Canal Opening (ASCO) offset relative to Bruch’s Membrane Opening (BMO) influences the Angular Location of Peak Retinal Nerve Fiber Layer Thickness (RNFLT) in Healthy Human Eyes

Seung Woo Hong; Hongli Yang; Stuart Keith Gardiner; Haomin Luo; Christy A Hardin; Glen Sharpe; Joseph Caprioli; Shaban Demirel; Christopher A Girkin; Jeffrey M Liebmann; Christian Y Mardin; Harry A Quigley; Alexander F Scheuerle; Brad Fortune; Balwantray C Chauhan; Claude F Burgoyne

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4740. doi:

ARVO Annual Meeting Abstract July 2019

Improved Detection of Optical Coherence Tomography (OCT) Structural Abnormality in Glaucoma (GL) with Combined Sectoral Rim and Retinal Nerve Fiber Layer (RNFL) Criteria

Hongli Yang; Haomin Luo; Christy A Hardin; Cindy Albert; Jayme Vianna; Glen Sharpe; Juan Reynaud; Shaban Demirel; Steven L Mansberger; Brad Fortune; Stuart Keith Gardiner; Balwantray C Chauhan; Claude F Burgoyne

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4818. doi:

ARVO Annual Meeting Abstract July 2019

Frequent non-intact axons and extensive extracellular debris in the optic nerve head at very early stages of non-human primate experimental glaucoma

Nicholas Marsh-Armstrong; Catherine Hou; Cheri Stowell; Imee Williams; Eric Bushong; Howard Lockwood; Juan Reynaud; Mark Ellisman; Claude F Burgoyne

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):670. doi:

ARVO Annual Meeting Abstract July 2019

Optical Coherence Tomography (OCT) Anterior Scleral Canal Opening (ASCO) Tilt and Rotation relative to Bruch’s Membrane Opening (BMO) and Peripapillary Scleral Bowing (PSB) in Healthy Eyes

Ya Xing Wang; Hongli Yang; Haomin Luo; Seung Woo Hong; Stuart Keith Gardiner; Jin Wook Jeoung; Joseph Caprioli; Shaban Demirel; Christopher A Girkin; Jeffrey M Liebmann; Christian Y Mardin; Harry A Quigley; Alexander F Scheuerle; Balwantray C Chauhan; Claude F Burgoyne

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5516. doi:

ARVO Annual Meeting Abstract July 2019

Machine Learning-Based Quantification of Axonal Damage in Glaucomatous Rat Optic Nerves

Bailey Hannon; Matthew Ritch; Robert Christian Ford; Arthur Thomas Read; Kristin Gao; Eva L. Dyer; Juan Reynaud; Grant Cull; Claude F Burgoyne; Machelle T Pardue; C Ross Ethier

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2854. doi:

ARVO Annual Meeting Abstract July 2019

Optical Coherence Tomography (OCT) Optic Nerve Head (ONH) Neural Canal Direction, Obliqueness and Minimum Cross-sectional Area in Highly Myopic versus Age-Matched Healthy Eyes

Jin Wook Jeoung; Hongli Yang; Stuart Keith Gardiner; Yaxing Wang; Seung Woo Hong; Michael J A Girard; Christy A Hardin; Ping Wei; Jayme Vianna; Balwantray C Chauhan; Claude F Burgoyne

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5552. doi:

ARVO Annual Meeting Abstract July 2019

Serial Block-Face Scanning EM (SBEM) Provides Evidence for Retrolaminar Demyelination of Structurally Intact Axons in Non-Human Primate (NHP) Early Experimental Glaucoma (EG)

Cheri Stowell; Eric Bushong; Howard Lockwood; Imee Williams; Juan Reynaud; Stuart Keith Gardiner; Nicholas Marsh-Armstrong; Mark Ellisman; Claude F Burgoyne

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5658. doi:

ARVO Annual Meeting Abstract July 2019

Optic nerve head (ONH) hypercompliance and blood flow autoregulation dysfunction detected by OCT-angiography (OCTA) in early-stage experimental glaucoma (EG)

Brad Fortune; Juan Reynaud; Christy A Hardin; Grant Cull; Lin Wang; Claude F Burgoyne

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4822. doi:

ARVO Annual Meeting Abstract July 2019

Optic nerve head prelaminar tissue schisis: a sign of glaucomatous deformation?

Eugene Lowry; Steven L Mansberger; Stuart Keith Gardiner; Hongli Yang; Facundo Gregorio Sanchez; David Sebastian Sanders; Shaban Demirel; Claude F Burgoyne; Brad Fortune

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5596. doi:

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Optic Nerve Head Myelin-Related Protein, GFAP, and Iba1 Alterations in Non-Human Primates With Early to Moderate Experimental Glaucoma

Decreased retrolaminar Myelin protein expression in Non-Human Primate (NHP) Early Experimental Glaucoma (EG) is accompanied by increased Iba1(+) cell counts and decreased GFAP signal intensity

Correlating longitudinal Optical Coherence Tomography (OCT) structural change to retrolaminar myelin-related protein alteration in non-human primate (NHP) early experimental glaucoma (EG)

Diagnostic accuracy of inner retinal layer thickness and reflectance intensity measurements assessed in posterior pole OCT scans of healthy and glaucomatous eyes

Optic Nerve Head Cavernous Voids in Glaucoma Suspect and Glaucoma Patients

Diagnostic accuracy of individual and combined retinal layer thickness measurements assessed at each pixel within posterior pole OCT scans of healthy and glaucomatous eyes

Asymmetry of Peripapillary Retinal Blood Vessel Position and Thickness in Healthy Right and Left Eyes

Novel Eye Drop Delivery Aid Preferred Over Traditional Eye Drop Delivery

Does loss of vasculature contribute to early stage glaucomatous thinning of the retinal nerve fiber layer (RNFL)?

Comparison of glaucoma diagnostic OCT parameters derived directly from circumpapillary and radial B-scans versus from raster grid scans

The Relationship Between Scleral Strain Change and Differential Cumulative Intraocular Pressure Exposure in the Nonhuman Primate Chronic Ocular Hypertension Model

Anterior Scleral Canal Opening (ASCO) offset relative to Bruch’s Membrane Opening (BMO) influences the Angular Location of Peak Retinal Nerve Fiber Layer Thickness (RNFLT) in Healthy Human Eyes

Improved Detection of Optical Coherence Tomography (OCT) Structural Abnormality in Glaucoma (GL) with Combined Sectoral Rim and Retinal Nerve Fiber Layer (RNFL) Criteria

Frequent non-intact axons and extensive extracellular debris in the optic nerve head at very early stages of non-human primate experimental glaucoma

Optical Coherence Tomography (OCT) Anterior Scleral Canal Opening (ASCO) Tilt and Rotation relative to Bruch’s Membrane Opening (BMO) and Peripapillary Scleral Bowing (PSB) in Healthy Eyes

Machine Learning-Based Quantification of Axonal Damage in Glaucomatous Rat Optic Nerves

Optical Coherence Tomography (OCT) Optic Nerve Head (ONH) Neural Canal Direction, Obliqueness and Minimum Cross-sectional Area in Highly Myopic versus Age-Matched Healthy Eyes

Serial Block-Face Scanning EM (SBEM) Provides Evidence for Retrolaminar Demyelination of Structurally Intact Axons in Non-Human Primate (NHP) Early Experimental Glaucoma (EG)

Optic nerve head (ONH) hypercompliance and blood flow autoregulation dysfunction detected by OCT-angiography (OCTA) in early-stage experimental glaucoma (EG)

Optic nerve head prelaminar tissue schisis: a sign of glaucomatous deformation?

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