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Glaucoma October 2024

Diagnostic Performance for Detection of Glaucomatous Structural Damage Using Pixelwise Analysis of Retinal Thickness Measurements

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Hongli Yang; Juan Reynaud; Glen P. Sharpe; Dawn Jennings; Cindy Albert; Trinity Holthausen; Xiue Jiang; Shaban Demirel; Steven L. Mansberger; Marcelo T. Nicolela; Stuart K. Gardiner; Balwantray C. Chauhan; Claude F. Burgoyne; Brad Fortune
TAGS: eye, glaucoma, pixel
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):17. https://doi.org/10.1167/iovs.65.12.17

Includes: Supplemental Content

ARVO Imaging in the Eye Conference Abstract July 2024

OCT Optic Nerve Head Neural Canal Exposed Scleral Flange Running Length and Bowing in Non-Highly Myopic Healthy and Highly Myopic Eyes

Anuwat Jiravarnsirikul; Nikola Meier; Yaxing Wang; Jin Wook Jeoung; Seung Woo Hong; Stuart Gardiner; Brad Fortune; Marcelo Nicolela; Linda Zangwill; Balwantray Chauhan; Claude Burgoyne; Hongli Yang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(9):PB00102.

ARVO Annual Meeting Abstract June 2024

Optic Nerve Head (ONH) Spatial Transcriptomics in Non-Human Primate (NHP) Experimental Glaucoma (EG)

Galen Williams; Jinho Lee; Cheri Stowell; Juan Reynaud; Hongli Yang; Stuart Keith Gardiner; Nicholas Marsh-Armstrong; Claude F Burgoyne; Priya Chaudhary

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):635.

Glaucoma February 2024

Retrolaminar Demyelination of Structurally Intact Axons in Nonhuman Primate Experimental Glaucoma

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Priya Chaudhary; Howard Lockwood; Cheri Stowell; Eric Bushong; Juan Reynaud; Hongli Yang; Stuart K. Gardiner; Galen Wiliams; Imee Williams; Mark Ellisman; Nick Marsh-Armstrong; Claude Burgoyne
TAGS: axon, eye, glaucoma, myelin, demyelination
Invest. Ophthalmol. Vis. Sci.. 2024; 65(2):36. https://doi.org/10.1167/iovs.65.2.36

ARVO Imaging in the Eye Conference Abstract June 2023

Localized orbital optic nerve axon loss estimates correlate with localized OCT measurements of retinal nerve fiber layer thickness (RNFLT) and minimum rim width (MRW) experimental glaucoma (EG).

Galen Williams; Priya Chaudhary; Juan Reynaud; Cheri Stowell; Grant Cull; Stuart Gardiner; Brad Fortune; Nick Marsh-Armstrong; Claude Burgoyne; Hongli Yang

Invest. Ophthalmol. Vis. Sci.. 2023; 64(9):PB0024.

ARVO Annual Meeting Abstract June 2023

Variability in Posterior Laminar Surface segmentation and colocalization does not affect the detection of significant increases in retrolaminar Myelin Onset Distance in Non-Human Primate Early Experimental Glaucoma

Priya Chaudhary; Howard Lockwood; Cheri Stowell; Juan Reynaud; Hongli Yang; Stuart Keith Gardiner; Galen Williams; Eric Bushong; Mark Ellisman; Nicholas Marsh-Armstrong; Claude Burgoyne

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1023.

ARVO Annual Meeting Abstract June 2023

During progression of glaucomatous damage, the rate of functional microvascular tissue loss exceeds loss of non-vascular tissue within the retinal nerve fiber layer, but declines proportionally within the optic nerve head neuroretinal rim

Brad Fortune; Grant Cull; Michaela Dunn; Dawn Jennings; Howard Lockwood; Trinity Holthausen; Stuart Keith Gardiner; Ian A Sigal; Claude Burgoyne; Adriana Di Polo

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3784.

ARVO Annual Meeting Abstract June 2023

Peri-Neural Canal Scleral Bowing and Choroidal Thickness in High Myopia

Hongli Yang; Ya Xing Wang; JInwook Jeoung; Seungwoo Hong; Stuart Keith Gardiner; Juan Reynaud; Brad Fortune; Michael J A Girard; Glen Sharpe; Marcelo Nicolela; Balwantray C Chauhan; Claude F Burgoyne

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4159.

ARVO Annual Meeting Abstract June 2023

Functional microvascular volume as a proportion of tissue volume is reduced in the RNFL but not the ONH rim at the onset of experimental glaucoma

Michaela Dunn; Juan Reynaud; Grant Cull; Dawn Jennings; Howard Lockwood; Trinity Holthausen; Stuart Keith Gardiner; Ian A Sigal; Claude F Burgoyne; Adriana Di Polo; Brad Fortune

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3779.

Artificial Intelligence March 2023

AxoNet 2.0: A Deep Learning-Based Tool for Morphometric Analysis of Retinal Ganglion Cell Axons

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Vidisha Goyal; A. Thomas Read; Matthew D. Ritch; Bailey G. Hannon; Gabriela Sanchez Rodriguez; Dillon M. Brown; Andrew J. Feola; Adam Hedberg-Buenz; Grant A. Cull; Juan Reynaud; Mona K. Garvin; Michael G. Anderson; Claude F. Burgoyne; C. Ross Ethier
TAGS: axon, datasets, learning
Trans. Vis. Sci. Tech.. 2023; 12(3):9. https://doi.org/10.1167/tvst.12.3.9

Includes: Supplemental Content

Glaucoma February 2023

Asymmetry of Peripapillary Retinal Blood Vessel and Retinal Nerve Fiber Layer Thickness Between Healthy Right and Left Eyes

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Jack Quach; Glen P. Sharpe; Shaban Demirel; Christopher A. Girkin; Christian Y. Mardin; Alexander F. Scheuerle; Claude F. Burgoyne; Balwantray C. Chauhan; Jayme R. Vianna
TAGS: eye, retinal nerve fiber layer, retinal vessels
Invest. Ophthalmol. Vis. Sci.. 2023; 64(2):17. https://doi.org/10.1167/iovs.64.2.17

Glaucoma October 2022

Optic Nerve Head Myelin-Related Protein, GFAP, and Iba1 Alterations in Non-Human Primates With Early to Moderate Experimental Glaucoma

PDF

Priya Chaudhary; Cheri Stowell; Juan Reynaud; Stuart K. Gardiner; Hongli Yang; Galen Williams; Imee Williams; Nicholas Marsh-Armstrong; Claude F. Burgoyne
TAGS: eye, glaucoma, glial fibrillary acidic protein, myelin, optic disk, pixel, proteins, optic nerve, primates, paraffin
Invest. Ophthalmol. Vis. Sci.. 2022; 63(11):9. https://doi.org/10.1167/iovs.63.11.9

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Decreased retrolaminar Myelin protein expression in Non-Human Primate (NHP) Early Experimental Glaucoma (EG) is accompanied by increased Iba1(+) cell counts and decreased GFAP signal intensity

Priya Chaudhary; Cheri Stowell; Juan Reynaud; Stuart Keith Gardiner; Galen Williams; Imee Williams; Nicholas Marsh-Armstrong; Claude F Burgoyne

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):933 – A0402.

ARVO Annual Meeting Abstract June 2022

Correlating longitudinal Optical Coherence Tomography (OCT) structural change to retrolaminar myelin-related protein alteration in non-human primate (NHP) early experimental glaucoma (EG)

Hongli Yang; Priya Chaudhary; Cheri Stowell; Juan Reynaud; Stuart Keith Gardiner; Galen Williams; Imee Williams; Nicholas Marsh-Armstrong; Claude F Burgoyne

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3095.

ARVO Annual Meeting Abstract June 2021

Diagnostic accuracy of inner retinal layer thickness and reflectance intensity measurements assessed in posterior pole OCT scans of healthy and glaucomatous eyes

Hongli Yang; Juan Reynaud; Glen P Sharpe; Dawn Jennings; Cindy Albert; Galen Williams; Xiue Jiang; Shaban Demirel; Steven L Mansberger; Jayme R Vianna; Marcelo Nicolela; Balwantray C Chauhan; Claude F Burgoyne; Stuart Keith Gardiner; Brad Fortune

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1836.

ARVO Annual Meeting Abstract June 2021

Optic Nerve Head Cavernous Voids in Glaucoma Suspect and Glaucoma Patients

Bennett Hong; Robert Kinast; Brad Fortune; Claude F Burgoyne; Steven L Mansberger

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3394.

ARVO Annual Meeting Abstract June 2020

Asymmetry of Peripapillary Retinal Blood Vessel Position and Thickness in Healthy Right and Left Eyes

Jack Quach; Glen P Sharpe; Shaban Demirel; Christopher A Girkin; Christian Y Mardin; Alexander Friedrich Scheuerle; Claude F Burgoyne; Balwantray C Chauhan; Jayme R Vianna

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3918.

ARVO Annual Meeting Abstract June 2020

Novel Eye Drop Delivery Aid Preferred Over Traditional Eye Drop Delivery

Facundo Gregorio Sanchez; Steven L Mansberger; Yungtai Kung; Stuart Keith Gardiner; Claude F Burgoyne; Emily P Jones; Robert M Kinast

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2663.

ARVO Annual Meeting Abstract June 2020

Does loss of vasculature contribute to early stage glaucomatous thinning of the retinal nerve fiber layer (RNFL)?

Brad Fortune; Juan Reynaud; Christy Hardin; Laura J Wilsey; Taylor Sund; Stuart Keith Gardiner; Claude F Burgoyne

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3531.

ARVO Annual Meeting Abstract June 2020

Comparison of glaucoma diagnostic OCT parameters derived directly from circumpapillary and radial B-scans versus from raster grid scans

Christy Hardin; Juan Reynaud; Laura J Wilsey; Taylor Sund; Stuart Keith Gardiner; Claude F Burgoyne; Brad Fortune

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4792.

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Diagnostic Performance for Detection of Glaucomatous Structural Damage Using Pixelwise Analysis of Retinal Thickness Measurements

OCT Optic Nerve Head Neural Canal Exposed Scleral Flange Running Length and Bowing in Non-Highly Myopic Healthy and Highly Myopic Eyes

Optic Nerve Head (ONH) Spatial Transcriptomics in Non-Human Primate (NHP) Experimental Glaucoma (EG)

Retrolaminar Demyelination of Structurally Intact Axons in Nonhuman Primate Experimental Glaucoma

Localized orbital optic nerve axon loss estimates correlate with localized OCT measurements of retinal nerve fiber layer thickness (RNFLT) and minimum rim width (MRW) experimental glaucoma (EG).

Variability in Posterior Laminar Surface segmentation and colocalization does not affect the detection of significant increases in retrolaminar Myelin Onset Distance in Non-Human Primate Early Experimental Glaucoma

During progression of glaucomatous damage, the rate of functional microvascular tissue loss exceeds loss of non-vascular tissue within the retinal nerve fiber layer, but declines proportionally within the optic nerve head neuroretinal rim

Peri-Neural Canal Scleral Bowing and Choroidal Thickness in High Myopia

Functional microvascular volume as a proportion of tissue volume is reduced in the RNFL but not the ONH rim at the onset of experimental glaucoma

AxoNet 2.0: A Deep Learning-Based Tool for Morphometric Analysis of Retinal Ganglion Cell Axons

Asymmetry of Peripapillary Retinal Blood Vessel and Retinal Nerve Fiber Layer Thickness Between Healthy Right and Left Eyes

Optic Nerve Head Myelin-Related Protein, GFAP, and Iba1 Alterations in Non-Human Primates With Early to Moderate Experimental Glaucoma

Decreased retrolaminar Myelin protein expression in Non-Human Primate (NHP) Early Experimental Glaucoma (EG) is accompanied by increased Iba1(+) cell counts and decreased GFAP signal intensity

Correlating longitudinal Optical Coherence Tomography (OCT) structural change to retrolaminar myelin-related protein alteration in non-human primate (NHP) early experimental glaucoma (EG)

Diagnostic accuracy of inner retinal layer thickness and reflectance intensity measurements assessed in posterior pole OCT scans of healthy and glaucomatous eyes

Optic Nerve Head Cavernous Voids in Glaucoma Suspect and Glaucoma Patients

Asymmetry of Peripapillary Retinal Blood Vessel Position and Thickness in Healthy Right and Left Eyes

Novel Eye Drop Delivery Aid Preferred Over Traditional Eye Drop Delivery

Does loss of vasculature contribute to early stage glaucomatous thinning of the retinal nerve fiber layer (RNFL)?

Comparison of glaucoma diagnostic OCT parameters derived directly from circumpapillary and radial B-scans versus from raster grid scans

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