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Meeting Abstract (47)
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Investigative Ophthalmology & Visual Science (67)

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ARVO Annual Meeting Abstract (47)
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ARVO Annual Meeting Abstract June 2022

Lutein, Zeaxanthin, and Meso-Zeaxanthin Supplementation Improves Multisensory Integration in Open-Angle Glaucoma.

Ekaterina Loskutova; John S Butler; Annalisa Setti; Gareth Lingham; Colm J O'Brien; James Loughman

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3881 – A0083. doi:

ARVO Annual Meeting Abstract June 2022

Higher Macular Pigment Levels are Associated with Better Contrast Sensitivity and Photostress Recovery Time in Patients with Open-Angle Glaucoma Supplemented with Carotenoids

Aoife Mary Louise Hunter; Ekaterina Loskutova; Gareth Lingham; Colm J O'Brien; John S Butler; James Loughman

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2699 – A0063. doi:

ARVO Annual Meeting Abstract June 2022

Serum c-reactive protein (CRP) relationship with macular pigment and response to carotenoid supplementation in open-angle glaucoma

Matilda Biba; Ekaterina Loskutova; Gareth Lingham; John S Butler; Colm J O'Brien; James Loughman

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2700 – A0064. doi:

Glaucoma January 2022

Matrix Mechanotransduction via Yes-Associated Protein in Human Lamina Cribrosa Cells in Glaucoma

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Rory Murphy; Mustapha Irnaten; Alan Hopkins; Jeffrey O'Callaghan; W. Daniel Stamer; Abbot F. Clark; Deborah Wallace; Colm J. O'Brien
TAGS: glaucoma, proteins, verteporfin, cribriform plate, mechanotransduction, cellular
Invest. Ophthalmol. Vis. Sci.. 2022; 63(1):16. doi: https://doi.org/10.1167/iovs.63.1.16

ARVO Annual Meeting Abstract June 2021

Elevated Expression of ADAM 12 and 19 in Human Glaucoma Lamina Cribrosa Cells

Aoife Smyth; Mustapha Irnaten; Sarah Kate Powell; Colm J O'Brien

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2770. doi:

ARVO Annual Meeting Abstract June 2021

Elucidating the Role of AMP-activated protein kinase (AMPK) in Human Glaucomatous Lamina Cribrosa (LC) cells

Sarah Kate Powell; Mustapha Irnaten; Aoife Smyth; Colm J O'Brien

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2764. doi:

ARVO Annual Meeting Abstract June 2021

The Role of the Lysophosphatidic Acid Axis in the Fibrotic Changes of the Lamina Cribrosa in Glaucoma

Amy O'Regan; Sarah B Eivers; Colm J O'Brien

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2756. doi:

ARVO Annual Meeting Abstract June 2021

Investigating the role of Plasminogen Activator Inhibitor-1 (PAI-1) in lamina cribrosa fibrosis using single cell RNA sequencing.

Caoimhe Normile; Mustapha Irnaten; David Simpson; Oisín Cappa; Abbot F Clark; Colm J O'Brien

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1650. doi:

ARVO Annual Meeting Abstract June 2021

Elucidating the role of p53 and MDM2 in glaucomatous lamina cribrosa cells.

Kealan McElhinney; Mustapha Irnaten; Deborah Wallace; Colm J O'Brien

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1642. doi:

ARVO Annual Meeting Abstract June 2021

Retinoblastoma signalling pathway inhibitor CDKN2B is regulated by promoter methylation in the lamina cribrosa region in primary open angle glaucoma

Sarah B Eivers; Colm J O'Brien

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1641. doi:

ARVO Annual Meeting Abstract June 2021

A Drug-Eluting Biomaterial Device for Reducing Post-Surgical Inflammation and Fibrosis in Glaucoma Patients

Alan Hibbitts; Mark Lemoine; Zülal Demir; Colm J O'Brien; Fergal O'Brien

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):628. doi:

ARVO Annual Meeting Abstract June 2021

Macular pigment response to carotenoid supplementation in patients with open angle glaucoma: the ENIGMA trial.

James Loughman; Colm J O'Brien; John S Butler; Ian Flitcroft; Ekaterina Loskutova

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2953. doi:

ARVO Annual Meeting Abstract June 2021

Bioenergetics Assessment and ECM gene expression in Glaucoma Lamina Cribrosa cells: Role of Metformin

Daire Hurley; Sophia Millington-Ward; Mustapha Irnaten; G. Jane Farrar; Colm J O'Brien

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2768. doi:

Glaucoma November 2020

Reduced Oxidative Phosphorylation and Increased Glycolysis in Human Glaucoma Lamina Cribrosa Cells

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Khalid Kamel; Colm J. O'Brien; Alexander V. Zhdanov; Dmitri B. Papkovsky; Abbot F. Clark; W. Daniel Stamer; Mustapha Irnaten

Invest. Ophthalmol. Vis. Sci.. 2020; 61(13):4. doi: https://doi.org/10.1167/iovs.61.13.4

ARVO Annual Meeting Abstract June 2020

Methylation regulates Lysyl oxidase like 1 (LOXL1) expression in Pseudoexfoliation Glaucoma

Alison G Greene; Sarah Eivers; Fiona McDonnell; Edward Dervan; Colm J O'Brien; Deborah Wallace

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1231. doi:

ARVO Annual Meeting Abstract June 2020

The mechanical rigidity of the extracellular matrix regulates the structure, proliferation and stiffness of human trabecular meshwork cells

Sarah Eivers; Baiyun Liu; Jason Kilpatrick; Bartlomiej Lukasz; Suzanne Jarvis; Abbot F Clark; Deborah Wallace; Colm J O'Brien

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3457. doi:

ARVO Annual Meeting Abstract June 2020

An Implantable Device for Reducing Post-Trabeculectomy Fibrosis in Glaucoma Patients

Alan Hibbitts; Mark Lemoine; Zulal Demir; Deirdre Brennan; Colm J O'Brien; Fergal O'Brien

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1418. doi:

ARVO Annual Meeting Abstract June 2020

Single-Cell RNA Sequencing of Lamina Cribrosa Fibroblasts in Glaucoma

Caoimhe Normile; Mustapha Irnaten; David A Simpson; Oisín Cappa; Colm J O'Brien

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2002. doi:

ARVO Annual Meeting Abstract July 2019

The Role of Yes-Associated Protein (YAP) in Mechanotransduction at the Lamina Cribrosa and its Potential as a Novel Therapeutic Target In Glaucoma.

Rory Murphy; Alan Hopkins; Mustapha Irnaten; W Daniel Stamer; Abbot F Clark; Deirdre Brennan; Deborah Wallace; Colm J O'Brien

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1786. doi:

ARVO Annual Meeting Abstract July 2019

TGF-β induces NOX4 and fibrotic genes in trabecular meshwork cells: role in glaucoma.

Reinold Kirton Goetz; Mustapha Irnaten; Colm J O'Brien

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3800. doi:

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Online ISSN: 1552-5783

Investigative Ophthalmology & Visual Science
Journal of Vision
Translational Vision Science & Technology

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