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ARVO Annual Meeting Abstract June 2025

An Investigation of Anaphylatoxins-Induced Expression of Human Endogenous Retroviruses (HERVs) in Retinal Pigment Epithelium Cells

Congxiao Zhang; Ruchi Sharma; David McGaughey; Andrew Fausey; Joys David; Katherine Patterson; Jair Montford; Devika Abhijit Bose; Jiwon Ryu; Omar Memon; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):740.

ARVO Annual Meeting Abstract June 2024

Localization of Toll-like Receptors and Intracellular Lipid Droplets in an anaphylatoxin-induced AMD model in iPSC-derived retinal pigment epithelium

Katherine Patterson; Congxiao Zhang; Andrew Fausey; David McGaughey; Joys Annita David; Ruchi Sharma; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):739.

ARVO Annual Meeting Abstract June 2024

Interferon regulatory factor 5 (IRF5) gene ablation causes senescencent changes in mouse choroid

Congxiao Zhang; Russell Quinn; Joys Annita David; Katherine Patterson; Eric Nguyen; Ruchi Sharma; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):732.

ARVO Annual Meeting Abstract June 2024

Macrophages induce choroidal senescence in an in vitro model of 3D RPE/choroid to cause neovascular AMD-like phenotypes

Tea Soon Park; Russell Quinn; Congxiao Zhang; Eric Nguyen; Casey Cargill; Devika Abhijit Bose; Min Jae Song; Marc Ferrer; ruchi Fnu; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4962.

ARVO Annual Meeting Abstract June 2024

Comparison of older and younger fibroblast in the homeostasis of 3D bioprinted oBRB model

Casey Cargill; Eric Nguyen; Amir Ali; Tea Soon Park; Rishabh Hirday; russell quinn; Colby F. Lewallen; Mitra Farnoodian; Congxiao Zhang; Davide Ortolan; Devika Abhijit Bose; Jair Montford; Omar Memon; Arvydas Maminishkis; ruchi Fnu; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4526.

ARVO Annual Meeting Abstract June 2023

Anaphylatoxins increase transposable element expression in human retinal pigment epithelium

Congxiao Zhang; Joys Annika David; David McGaughey; Andrew Fausey; Ruchi Sharma; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2093.

ARVO Annual Meeting Abstract June 2023

Piezo1 channels highly expressed in human RPE

Qin Wan; Joys Annika David; Congxiao Zhang; Tea Soon Park; Mitra Farnoodian; Eric Nguyen; Jair Montford; Colby Lewallen; Aman George; Kiyoharu Miyagishima; David McGaughey; Davide Ortolan; Devika Abhijit Bose; Arvydas Maminishkis; Ruchi Sharma; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2982.

ARVO Annual Meeting Abstract June 2022

Senescent Macrophage Lead to Age Related Macular Degeneration-Like Phenotype in an in vitro 3D RPE/Choroid Model

Russell Quinn; Eric Nguyen; Tea Soon Park; Congxiao Zhang; Amir Ali; Rishabh Hirday; Devika Bose; Robert N Fariss; Marc Ferrer; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):24.

ARVO Annual Meeting Abstract June 2022

Targeted deletion of interferon regulatory factor 5 gene in mice triggers choroidal neovascularization

Congxiao Zhang; Russell Quinn; Eric Nguyen; Nilisha Fernando; Joys Annika G David; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3477.

ARVO Annual Meeting Abstract June 2022

TLR3 and TLR4 regulate complement-induced AMD cellular phenotype in iPSC-derived retinal pigment epithelium

Joys Annika G David; Congxiao Zhang; Andrew Fausey; Ruchi Sharma; Mitra Farnoodian; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4614 – F0406.

ARVO Annual Meeting Abstract June 2021

Human retinal pigment epithelium secretes insulin-like growth factor 2 in vitro

Charles DeYoung; Tyler Pfister; Congxiao Zhang; Aman George; Kapil Bharti; Tiziana Cogliati; Brian Patrick Brooks

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2991.

ARVO Annual Meeting Abstract June 2021

Interaction between CTRP5 & AdipoR1 and its implication to Late-onset retinal degeneration (L-ORD)

Andrew Fausey; Congxiao Zhang; Malika Nimmagadda; Kiyoharu Joshua Miyagishima; Ruchi Sharma; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3062.

ARVO Annual Meeting Abstract June 2020

Hypoxia-induced Alterations of miR-204 Regulates Autophagy Activity in Human Retinal Pigment Epithelium (hRPE)

Congxiao Zhang; Kiyoharu J Miyagishima; Ruchi Sharma; Malika Nimmagadda; Genqing Liang; Arvydas Maminishkis; Kapil Bharti; Sheldon S Miller

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3110.

ARVO Annual Meeting Abstract July 2019

Elevation of miR-155 induces a non-canonical inflammasome activation pathway in human retinal pigment epithelium (hRPE)

Congxiao Zhang; Arvydas Maminishkis; Kiyoharu miyagishima; Genqing Liang; Fnu Ruchi; Sheldon S Miller

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):766.

ARVO Annual Meeting Abstract July 2019

Regional transcriptome map of the adult rhesus macaque retina and RPE-choroid

Ameera Mungale; Temesgen D Fufa; David McGaughey; Congxiao Zhang; Arvydas Maminishkis; Sheldon S Miller; Brian Patrick Brooks; Robert Hufnagel

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):998.

ARVO Annual Meeting Abstract July 2019

Differential transcriptome profile associated with pigmentation defects in induced pluripotent stem cell-derived retinal pigment epithelium from Albinism patients

Aman George; Fnu Ruchi; Tyler Pfister; David McGaughey; Nathan Hotaling; Mones S Abu-Asab; Qin Wan; Congxiao Zhang; Kapil Bharti; Brian Patrick Brooks

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2877.

ARVO Annual Meeting Abstract June 2017

Analysis of Secretory Lipidomics and Proteomics of Late-Onset Retinal Degeneration iPSC-derived RPE

Kiyoharu J Miyagishima; Ruchi Sharma; Katharina Clore-Gronenborn; Zoya Qureshy; Bokkyoo Jun; William C Gordon; Nathan Hotaling; Congxiao Zhang; Catherine A Cukras; Paul A Sieving; Nicolas Guillermo Bazan; Sheldon S Miller; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3019.

ARVO Annual Meeting Abstract June 2017

RPE miR-204 or -211 KNOCK OUT ALTERS CELL MORPHOLOGY AND FUNCTION

Congxiao Zhang; Helen Zhao; Nathan Hotaling; Kiyoharu Miyagishima; Raymond Zhou; Lijing Dong; Arvydas Maminishkis; Kapil Bharti; Sheldon S Miller

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3568.

ARVO Annual Meeting Abstract June 2017

Visual function following Nitisinone treatment in a mouse model of OCA-1B (Tyr c-h/c-h )

Ighovie Felix Onojafe; Friedrich Kretschmer; Jung-Woong Kim; Kiyoharu Miyagishima; Congxiao Zhang; Haohua Qian; Tudor C Badea; Brian Patrick Brooks

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5868.

ARVO Annual Meeting Abstract September 2016

Functional Validation of GLP-grade Induced Pluripotent Stem Cell Derived Retinal Pigment Epithelium: developing a Cell Therapy for AMD.

Fnu Ruchi; Vladimir Khristov; Balendu Jha; Dishita Patel; Qin Wan; Nathan Hotaling; Congxiao Zhang; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2127.

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