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ARVO Annual Meeting Abstract June 2025

Insight into the ARMS2 gene region: long non-coding RNA HTRA1-AS1 and a 5-SNP block affecting protein-interaction are associated with AMD

Pingwu Zhang; Sheng Liu; Srinivasa Rao Sripathi; Weifeng Li; Zi-He Wan; Sean Li; Laura Fan; Casey Keuthan; Cynthia Berlinicke; Shannath L Merbs; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4607.

ARVO Annual Meeting Abstract June 2025

Oligodendrocyte-specific knock-out of glutathione peroxidase-4 delays visual evoked potential implicit time and provides a potential new optic neuropathy model.

Abhishek Vats; Kavita Vats; Cheng Qian; Kunal Singh; Aman Shah; Kunal Mehta; Cynthia Berlinicke; Yuri L Bunimovich; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2329.

ARVO Annual Meeting Abstract June 2025

CRISPRi Screening Identifies Potential Protective Targets for Retinal Ganglion Cell Survival Under Axon Damage

Weifeng Li; Yukan Duan; Cynthia Berlinicke; Xitiz Chamling; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2659.

ARVO Annual Meeting Abstract June 2025

Amiloride inhibits sterile alpha and toll/interleukin receptor motif-containing protein 1 (SARM1) activity and delays axon degeneration

Sean Christopher Chapman; Amit K Patel; Maria Paula Avila; Cynthia Berlinicke; Sophie Chayoung Kim; Julian Bahramipour; Kathy Michelle Oraha; Donald J Zack; Derek S. Welsbie

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3410.

ARVO Annual Meeting Abstract June 2024

Analyzing mRNA isoforms in human stem cell-derived retinal neurons using long-read transcriptomics

Casey J Keuthan; Sowmya Parthiban; Yen Yu Chang; Xiaoli Chang; Ethan Yan; Cynthia Berlinicke; Sheridan Cavalier; Corina Anastasaki; David Gutmann; David M Gamm; Yuan Zhu; Winston Timp; Stephanie Hicks; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4697.

ARVO Annual Meeting Abstract June 2023

The kinase inhibitor SBJ-051 protects mice from light damage and attenuates photoreceptor degeneration in a genetic mouse model of retinitis pigmentosa

Pingwu Zhang; Brendan Lilley; Stacey Cole; Cynthia Berlinicke; Gloria Li; Derek Welsbie; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4890.

ARVO Annual Meeting Abstract June 2023

Single-cell RNA-seq of Human Embryonic Stem Cell-derived Retinal Ganglion Cells Unravels New Potential Regulators of Retinal Ganglion Cell Differentiation

Weifeng Li; Cynthia A Berlinicke; Jie Cheng; Xiaoli Chang; Felipe Takaesu; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3204.

ARVO Annual Meeting Abstract June 2023

CRISPR interference knockdown of Dynamin-Related Protein 1 ( DRP1 ) restores mitochondrial homeostasis disrupted by inhibition of Optic Atrophy 1 ( OPA1) expression

Jie Cheng; Yukan Duan; Cynthia A Berlinicke; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1897.

ARVO Annual Meeting Abstract June 2023

Investigating the function of BLIMP1 on bipolar and photoreceptor cell development in human retinal organoids

Yen Yu Chang; Casey J. Keuthan; Claire Bell; Xitiz Chamling; Ah Yang; Cynthia A Berlinicke; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4494.

Cornea July 2022

Integrated Stress Response Regulation of Corneal Epithelial Cell Motility and Cytokine Production

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Hsiao-Sang Chu; Cornelia Peterson; Xitiz Chamling; Cynthia Berlinicke; Donald Zack; Albert S. Jun; James Foster
TAGS: agonists, cell lines, cell motility, corneal epithelial cells, corneal epithelium, cyclophosphamide, doxorubicin, prednisone, and vincristine, cytokine, regulation, stress response, cornea
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):1. https://doi.org/10.1167/iovs.63.8.1

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

High content screen for small molecules that inhibit epithelial to mesenchymal transition in human stem cell-derived RPE cells

Srinivasa Sripathi; Cynthia Berlinicke; Xitiz Chamling; Rebekah Mikeasky; Yukan Duan; Caire Bell; Ming-Wen Hu; Julien Maruotti; Karl J Wahlin; Jiang Qian; Noriko Esumi; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):683 – F0137.

ARVO Annual Meeting Abstract June 2022

Histone Deacetylase and Myosin Inhibitors Promote Neurite Outgrowth in Injured Retinal Ganglion Cells Derived from Human Pluripotent Stem Cells

Jie Cheng; Shuaizhang Li; Cynthia Berlinicke; Pingwu Zhang; Xiaoli Chang; Derek Stuart Welsbie; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2445 – F0389.

ARVO Annual Meeting Abstract June 2022

Investigating the cell autonomous effects of NF1 mutation on human RGC development and survival

Casey Keuthan; Shuaizhang Li; Pingwu Zhang; Corina Anastasaki; Cynthia Berlinicke; Yuan Zhu; David Gutmann; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3910 – A0112.

ARVO Annual Meeting Abstract June 2021

Simultaneous single-cell lineage tracing and transcriptomics of the developing mammalian retina

Claire Bell; Weixiang Fang; Stacey Cole; Kathleen Leeper; Cynthia Berlinicke; Pengfei Zhang; Tza-Huei Wang; Hongkai Ji; Reza Kalhor; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2614.

Biochemistry and Molecular Biology April 2021

Transcriptome Landscape of Epithelial to Mesenchymal Transition of Human Stem Cell–Derived RPE

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Srinivasa R. Sripathi; Ming-Wen Hu; Melissa M. Liu; Jun Wan; Jie Cheng; Yukan Duan; Joseph L. Mertz; Karl J. Wahlin; Julien Maruotti; Cynthia A. Berlinicke; Jiang Qian; Donald J. Zack
TAGS: epithelial to mesenchymal transition, dissociation, tumor necrosis factors, gene expression profiling
Invest. Ophthalmol. Vis. Sci.. 2021; 62(4):1. https://doi.org/10.1167/iovs.62.4.1

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Probing the Differentiation of Retinal Ganglion Cells from Human Embryonic Stem Cells with Inducible CRISPR Interference

Jie Cheng; Xiaoli Chang; Yukan Duan; Cynthia Berlinicke; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3794.

ARVO Annual Meeting Abstract June 2020

Single-cell lineage tracing of developing retinal systems

Claire Bell; Weixiang Fang; Cynthia Berlinicke; Aniruddhah Kaushik; Pengfei Zhang; Tza-Huei Wang; Reza Kalhor; Hongkai Ji; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4014.

ARVO Annual Meeting Abstract June 2020

Development of a Screening Platform that uses Genome Engineered hPSC-Derived OPCs for the Discovery of Remyelination Promoting Compounds

xitiz chamling; Cynthia Berlinicke; Yukan Duan; Xiaoli Chang; Peter Calabresi; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5184.

ARVO Annual Meeting Abstract July 2019

Proteomic Approaches to Study Cell Death Mechanisms in Human Stem Cell-Derived Retinal Ganglion Cells

Joseph L Mertz; Xitiz Chamling; David J Clark; Kyung Cho Cho; Cynthia Berlinicke; Hui Zhang; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):629.

ARVO Annual Meeting Abstract July 2019

Inhibition of NF-kB signaling modulates epithelial to mesenchymal transition in human stem cell-derived retinal pigment epithelial cells

Srinivas Rao Sripathi; Ming-Wen Hu; Jie Cheng; Melissa Liu; Yukan Duan; Jun Wan; Xue Yang; Joseph L Mertz; Cynthia Berlinicke; Julien Maruotti; Karl J Wahlin; Noriko Esumi; Jiang Qian; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1738.

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Insight into the ARMS2 gene region: long non-coding RNA HTRA1-AS1 and a 5-SNP block affecting protein-interaction are associated with AMD

Oligodendrocyte-specific knock-out of glutathione peroxidase-4 delays visual evoked potential implicit time and provides a potential new optic neuropathy model.

CRISPRi Screening Identifies Potential Protective Targets for Retinal Ganglion Cell Survival Under Axon Damage

Amiloride inhibits sterile alpha and toll/interleukin receptor motif-containing protein 1 (SARM1) activity and delays axon degeneration

Analyzing mRNA isoforms in human stem cell-derived retinal neurons using long-read transcriptomics

The kinase inhibitor SBJ-051 protects mice from light damage and attenuates photoreceptor degeneration in a genetic mouse model of retinitis pigmentosa

Single-cell RNA-seq of Human Embryonic Stem Cell-derived Retinal Ganglion Cells Unravels New Potential Regulators of Retinal Ganglion Cell Differentiation

CRISPR interference knockdown of Dynamin-Related Protein 1 ( DRP1 ) restores mitochondrial homeostasis disrupted by inhibition of Optic Atrophy 1 ( OPA1) expression

Investigating the function of BLIMP1 on bipolar and photoreceptor cell development in human retinal organoids

Integrated Stress Response Regulation of Corneal Epithelial Cell Motility and Cytokine Production

High content screen for small molecules that inhibit epithelial to mesenchymal transition in human stem cell-derived RPE cells

Histone Deacetylase and Myosin Inhibitors Promote Neurite Outgrowth in Injured Retinal Ganglion Cells Derived from Human Pluripotent Stem Cells

Investigating the cell autonomous effects of NF1 mutation on human RGC development and survival

Simultaneous single-cell lineage tracing and transcriptomics of the developing mammalian retina

Transcriptome Landscape of Epithelial to Mesenchymal Transition of Human Stem Cell–Derived RPE

Probing the Differentiation of Retinal Ganglion Cells from Human Embryonic Stem Cells with Inducible CRISPR Interference

Single-cell lineage tracing of developing retinal systems

Development of a Screening Platform that uses Genome Engineered hPSC-Derived OPCs for the Discovery of Remyelination Promoting Compounds

Proteomic Approaches to Study Cell Death Mechanisms in Human Stem Cell-Derived Retinal Ganglion Cells

Inhibition of NF-kB signaling modulates epithelial to mesenchymal transition in human stem cell-derived retinal pigment epithelial cells

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