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ARVO Annual Meeting Abstract July 2019

Inhibition of NF-kB signaling modulates epithelial to mesenchymal transition in human stem cell-derived retinal pigment epithelial cells

Srinivas Rao Sripathi; Ming-Wen Hu; Jie Cheng; Melissa Liu; Yukan Duan; Jun Wan; Xue Yang; Joseph L Mertz; Cynthia Berlinicke; Julien Maruotti; Karl J Wahlin; Noriko Esumi; Jiang Qian; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1738. doi:

ARVO Annual Meeting Abstract July 2019

MAP4K4 and GSK-3 pathways complement DLK/LZK signaling to control cell death and axon degeneration in retinal ganglion cells

Amit K Patel; Katy Mitchell; Baranda S. Hansen; Cindy Berlinicke; Risa Broyer; Donald J Zack; Derek Stuart Welsbie

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2255. doi:

ARVO Annual Meeting Abstract July 2019

Single-cell transcriptomic analysis of human NRL null retinal organoids

Donald J Zack; Alyssa Kallman; Elizabeth E. Capowski; Anu Kaushik; Liben Chen; Melissa Liu; Alex Jansen; Kim Edwards; Cindy Berlinicke; Ming-Wen Hu; Jiang Qian; Eric A Pierce; Jeff Wang; David M Gamm

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4766. doi:

ARVO Annual Meeting Abstract July 2019

Gene regulation dynamics induced by the protein kinase inhibitor, SBJ-051 associated with neuroprotection in light-induced photoreceptor cell death

Byung-Jin Kim; Jie Wang; Tomohiro Masuda; Melissa Liu; Reji Nair; Jiang Qian; Derek Stuart Welsbie; Thomas Bannister; Timothy Spicer; Louis Scampavia; George Trainor; Amy Trainor; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4863. doi:

ARVO Annual Meeting Abstract July 2019

Neuroprotection of retinal ganglion cells by BMSC-derived exosomes

Ben Mead; Donald J Zack; Zubair Ahmed; Stanislav I Tomarev

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5174. doi:

ARVO Annual Meeting Abstract July 2019

“Cellular heterogeneity of human stem cell-derived RGCs”

Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5636. doi:

ARVO Annual Meeting Abstract July 2019

Thyroid hormone signaling specifies cone subtypes in human retinal organoids

Robert J Johnston; Kiara Eldred; Sarah Hadyniak; Katarzyna Hussey; Boris Brenerman; Ping-Wu Zhang; Xitiz Chamling; Valentin Sluch; Derek Stuart Welsbie; Samer Hattar; James Taylor; Karl J Wahlin; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6405. doi:

ARVO Annual Meeting Abstract July 2019

Proteomic Approaches to Study Cell Death Mechanisms in Human Stem Cell-Derived Retinal Ganglion Cells

Joseph L Mertz; Xitiz Chamling; David J Clark; Kyung Cho Cho; Cynthia Berlinicke; Hui Zhang; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):629. doi:

ARVO Annual Meeting Abstract July 2019

Switching from the proteasomal to the lysosomal pathway for MQC during human RGC differentiation is essential for RGC survival

Arupratan Das; Claire Wenger; Cindy Berlinicke; Nicholas Marsh-Armstrong; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):654. doi:

ARVO Annual Meeting Abstract July 2019

Methods to improve and quantify retinal integration of transplanted stem cell-derived retinal ganglion cells for optic nerve regeneration

Thomas Vincent Johnson; Caitlyn Tuffy; Joseph L Mertz; Harry A Quigley; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):652. doi:

Perspective July 2018

Inherited Retinal Degenerations: Current Landscape and Knowledge Gaps

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Jacque L. Duncan; Eric A. Pierce; Amy M. Laster; Stephen P. Daiger; David G. Birch; John D. Ash; Alessandro Iannaccone; John G. Flannery; José A. Sahel; Donald J. Zack; Marco A. Zarbin; and the Foundation Fighting Blindness Scientific Advisory Board
TAGS: mutation, genetics, genes, animal model, retinal degeneration, comprehension
Trans. Vis. Sci. Tech.. 2018; 7(4):6. doi: 10.1167/tvst.7.4.6

ARVO Annual Meeting Abstract July 2018

Large-scale Whole-organism Phenotypic Screen Identifies Rod Cell Neuroprotectants Effective in Zebrafish and Mouse Models of Retinitis Pigmentosa

Liyun Zhang; Conan Chen; Jiang Qian; Hongkai Ji; Donald J Zack; Justin Hanes; David Ackerley; Baerbel Rohrer; Jeff S Mumm

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):980. doi:

ARVO Annual Meeting Abstract July 2018

Polymeric Nanoparticles: A promising platform for gene delivery to RPE monolayers

Bibhudatta Mishra; David R. Wilson; Srinivas R. Sripathi; Yuan Rui; Mark P. Suprenant; Baranda S. Hansen; Cynthia Berlinicke; Jordan Green; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2466. doi:

ARVO Annual Meeting Abstract July 2018

Single-cell transcriptomic analysis of human and murine NRL-null retinas

Alyssa Kallman; Elizabeth E Capowski; Aniruddha M. Kaushik; Melissa Liu; Baranda S. Hansen; Liben Chen; Jie Cheng; Karl Wahlin; Ming-Wen Hu; Loyal A Goff; Jiang Qian; Cynthia Berlinicke; Jeff (Tza-Huei) Wang; David M Gamm; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3105. doi:

ARVO Annual Meeting Abstract July 2018

Genetic deletion of DLK and LZK reduce colchicine-induced cell death in human s tem cell-derived retinal ganglion cells

Pingwu Zhang; Yukan Duan; Jie Cheng; Cynthia Berlinicke; Amit K Patel; Derek Stuart Welsbie; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6152. doi:

ARVO Annual Meeting Abstract July 2018

Single-Cell Transcriptome Profiling of Human Stem Cell-Derived Retinal Ganglion Cells in a Dominant Optic Atrophy Model

Jie Cheng; Melissa Liu; Aniruddha M. Kaushik; Xiaoli Chang; Yukan Duan; Liben Chen; Jeff (Tza-Huei) Wang; Cynthia Berlinicke; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1988. doi:

ARVO Annual Meeting Abstract July 2018

Identification of a retinal neuroprotective kinase inhibitor with preferential activity against DLK compared to LZK

Derek Stuart Welsbie; Hartmut Schirok; Katherine Mitchell; Michael Koch; Byung-Jin Kim; Mario Lobell; Amit K Patel; Simon Holton; Dmitrij Hristodorov; Julian Esteve-Rudd; Cynthia Berlinicke; Carsten Terjung; Baranda S. Hansen; Nicolas Werbeck; William Schubert; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2493. doi:

ARVO Annual Meeting Abstract July 2018

Identification of MAP4K4/GSK-3 as a parallel acting pathway with DLK/LZK signaling to control cell death programs in retinal ganglion cells

Amit K Patel; Katherine Mitchell; Baranda Hansen; Cindy Berlinicke; Miranda Montgomery; Risa Broyer; Donald J Zack; Derek Stuart Welsbie

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2612. doi:

ARVO Annual Meeting Abstract July 2018

Epithelial to mesenchymal transition of human stem cell-derived retinal pigment epithelium cells modulates expression of axonal guidance molecules

Srinivas Rao Sripathi; Melissa M Liu; Ming-Wen Hu; Jun Wan; Jie Cheng; Joseph L Mertz; Cynthia Berlinicke; Julien Maruotti; Karl Wahlin; Jiang Qian; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4002. doi:

Glaucoma February 2018

Testosterone Pathway Genetic Polymorphisms in Relation to Primary Open-Angle Glaucoma: An Analysis in Two Large Datasets

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Jessica N. Cooke Bailey; Puya Gharahkhani; Jae H. Kang; Mariusz Butkiewicz; David A. Sullivan; Robert N. Weinreb; Hugues Aschard; R. Rand Allingham; Allison Ashley-Koch; Richard K. Lee; Sayoko E. Moroi; Murray H. Brilliant; Gadi Wollstein; Joel S. Schuman; John H. Fingert; Donald L. Budenz; Tony Realini; Terry Gaasterland; William K. Scott; Kuldev Singh; Arthur J. Sit; Robert P. Igo, Jr; Yeunjoo E. Song; Lisa Hark; Robert Ritch; Douglas J. Rhee; Douglas Vollrath; Donald J. Zack; Felipe Medeiros; Thasarat S. Vajaranant; Daniel I. Chasman; William G. Christen; Margaret A. Pericak-Vance; Yutao Liu; Peter Kraft; Julia E. Richards; Bernard A. Rosner; Michael A. Hauser; Jamie E. Craig; Kathryn P. Burdon; Alex W. Hewitt; David A. Mackey; Jonathan L. Haines; Stuart MacGregor; Janey L. Wiggs; Louis R. Pasquale; for the Australian and New Zealand Registry of Advanced Glaucoma (ANZRAG) Consortium
TAGS: testosterone, metabolism, polymorphism, glaucoma, genes, open-angle glaucoma, datasets
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):629-636. doi: 10.1167/iovs.17-22708

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Inhibition of NF-kB signaling modulates epithelial to mesenchymal transition in human stem cell-derived retinal pigment epithelial cells

MAP4K4 and GSK-3 pathways complement DLK/LZK signaling to control cell death and axon degeneration in retinal ganglion cells

Single-cell transcriptomic analysis of human NRL null retinal organoids

Gene regulation dynamics induced by the protein kinase inhibitor, SBJ-051 associated with neuroprotection in light-induced photoreceptor cell death

Neuroprotection of retinal ganglion cells by BMSC-derived exosomes

“Cellular heterogeneity of human stem cell-derived RGCs”

Thyroid hormone signaling specifies cone subtypes in human retinal organoids

Proteomic Approaches to Study Cell Death Mechanisms in Human Stem Cell-Derived Retinal Ganglion Cells

Switching from the proteasomal to the lysosomal pathway for MQC during human RGC differentiation is essential for RGC survival

Methods to improve and quantify retinal integration of transplanted stem cell-derived retinal ganglion cells for optic nerve regeneration

Inherited Retinal Degenerations: Current Landscape and Knowledge Gaps

Large-scale Whole-organism Phenotypic Screen Identifies Rod Cell Neuroprotectants Effective in Zebrafish and Mouse Models of Retinitis Pigmentosa

Polymeric Nanoparticles: A promising platform for gene delivery to RPE monolayers

Single-cell transcriptomic analysis of human and murine NRL-null retinas

Genetic deletion of DLK and LZK reduce colchicine-induced cell death in human s tem cell-derived retinal ganglion cells

Single-Cell Transcriptome Profiling of Human Stem Cell-Derived Retinal Ganglion Cells in a Dominant Optic Atrophy Model

Identification of a retinal neuroprotective kinase inhibitor with preferential activity against DLK compared to LZK

Identification of MAP4K4/GSK-3 as a parallel acting pathway with DLK/LZK signaling to control cell death programs in retinal ganglion cells

Epithelial to mesenchymal transition of human stem cell-derived retinal pigment epithelium cells modulates expression of axonal guidance molecules

Testosterone Pathway Genetic Polymorphisms in Relation to Primary Open-Angle Glaucoma: An Analysis in Two Large Datasets

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