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ARVO Annual Meeting Abstract June 2020

Probing the Differentiation of Retinal Ganglion Cells from Human Embryonic Stem Cells with Inducible CRISPR Interference

Jie Cheng; Xiaoli Chang; Yukan Duan; Cynthia Berlinicke; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3794. doi:

ARVO Annual Meeting Abstract June 2020

Physiological and morphological development of human embryonic stem cell derived retinal ganglion cells

Michael L Risner; Cathryn Formichella; xitiz chamling; Thomas A Reh; Jeffrey Louis Goldberg; Donald J Zack; David J Calkins

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3871. doi:

ARVO Annual Meeting Abstract June 2020

Single-cell lineage tracing of developing retinal systems

Claire Bell; Weixiang Fang; Cynthia Berlinicke; Aniruddhah Kaushik; Pengfei Zhang; Tza-Huei Wang; Reza Kalhor; Hongkai Ji; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4014. doi:

ARVO Annual Meeting Abstract June 2020

Development of a Screening Platform that uses Genome Engineered hPSC-Derived OPCs for the Discovery of Remyelination Promoting Compounds

xitiz chamling; Cynthia Berlinicke; Yukan Duan; Xiaoli Chang; Peter Calabresi; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5184. doi:

ARVO Annual Meeting Abstract June 2020

Lysosome dependent mitophagy is critical for human RGC survival which is disrupted in glaucoma-associated Optineurin E50K mutation

Arupratan Das; Nicholas Marsh-Armstrong; Jason S Meyer; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):265. doi:

ARVO Annual Meeting Abstract June 2020

Enzymatic disruption of retinal extracellular matrix affects surface topology of transplanted human retinal ganglion cells

Kevin Y Zhang; Caitlyn Tuffy; Joseph L Mertz; Harry A Quigley; Donald J Zack; Thomas Vincent Johnson

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):635. doi:

ARVO Annual Meeting Abstract June 2020

Structural incorporation of transplanted human retinal ganglion cell neurites following proteolytic digestion or transgenic disruption of retinal extracellular matrix components

Thomas Vincent Johnson; Caitlyn Tuffy; Kevin Zhang; Joseph L Mertz; Harry A Quigley; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1163. doi:

Visual Neuroscience February 2020

TNFα-Mediated Priming of Mesenchymal Stem Cells Enhances Their Neuroprotective Effect on Retinal Ganglion Cells

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Ben Mead; Xitiz Chamling; Donald J. Zack; Zubair Ahmed; Stanislav Tomarev
TAGS: culture media, conditioned, exosomes, neuroprotection, neuroprotective effect, retinal ganglion cells, stem cell, mesenchymal, cell culture techniques
Invest. Ophthalmol. Vis. Sci.. 2020; 61(2):6. doi: https://doi.org/10.1167/iovs.61.2.6

ARVO Annual Meeting Abstract July 2019

Thyroid hormone signaling specifies cone subtypes in human retinal organoids

Robert J Johnston; Kiara Eldred; Sarah Hadyniak; Katarzyna Hussey; Boris Brenerman; Ping-Wu Zhang; Xitiz Chamling; Valentin Sluch; Derek Stuart Welsbie; Samer Hattar; James Taylor; Karl J Wahlin; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6405. doi:

ARVO Annual Meeting Abstract July 2019

Methods to improve and quantify retinal integration of transplanted stem cell-derived retinal ganglion cells for optic nerve regeneration

Thomas Vincent Johnson; Caitlyn Tuffy; Joseph L Mertz; Harry A Quigley; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):652. doi:

ARVO Annual Meeting Abstract July 2019

Inhibition of NF-kB signaling modulates epithelial to mesenchymal transition in human stem cell-derived retinal pigment epithelial cells

Srinivas Rao Sripathi; Ming-Wen Hu; Jie Cheng; Melissa Liu; Yukan Duan; Jun Wan; Xue Yang; Joseph L Mertz; Cynthia Berlinicke; Julien Maruotti; Karl J Wahlin; Noriko Esumi; Jiang Qian; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1738. doi:

ARVO Annual Meeting Abstract July 2019

MAP4K4 and GSK-3 pathways complement DLK/LZK signaling to control cell death and axon degeneration in retinal ganglion cells

Amit K Patel; Katy Mitchell; Baranda S. Hansen; Cindy Berlinicke; Risa Broyer; Donald J Zack; Derek Stuart Welsbie

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2255. doi:

ARVO Annual Meeting Abstract July 2019

Single-cell transcriptomic analysis of human NRL null retinal organoids

Donald J Zack; Alyssa Kallman; Elizabeth E. Capowski; Anu Kaushik; Liben Chen; Melissa Liu; Alex Jansen; Kim Edwards; Cindy Berlinicke; Ming-Wen Hu; Jiang Qian; Eric A Pierce; Jeff Wang; David M Gamm

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4766. doi:

ARVO Annual Meeting Abstract July 2019

Gene regulation dynamics induced by the protein kinase inhibitor, SBJ-051 associated with neuroprotection in light-induced photoreceptor cell death

Byung-Jin Kim; Jie Wang; Tomohiro Masuda; Melissa Liu; Reji Nair; Jiang Qian; Derek Stuart Welsbie; Thomas Bannister; Timothy Spicer; Louis Scampavia; George Trainor; Amy Trainor; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4863. doi:

ARVO Annual Meeting Abstract July 2019

Neuroprotection of retinal ganglion cells by BMSC-derived exosomes

Ben Mead; Donald J Zack; Zubair Ahmed; Stanislav I Tomarev

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5174. doi:

ARVO Annual Meeting Abstract July 2019

“Cellular heterogeneity of human stem cell-derived RGCs”

Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5636. doi:

ARVO Annual Meeting Abstract July 2019

Switching from the proteasomal to the lysosomal pathway for MQC during human RGC differentiation is essential for RGC survival

Arupratan Das; Claire Wenger; Cindy Berlinicke; Nicholas Marsh-Armstrong; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):654. doi:

ARVO Annual Meeting Abstract July 2019

Proteomic Approaches to Study Cell Death Mechanisms in Human Stem Cell-Derived Retinal Ganglion Cells

Joseph L Mertz; Xitiz Chamling; David J Clark; Kyung Cho Cho; Cynthia Berlinicke; Hui Zhang; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):629. doi:

Perspective July 2018

Inherited Retinal Degenerations: Current Landscape and Knowledge Gaps

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Jacque L. Duncan; Eric A. Pierce; Amy M. Laster; Stephen P. Daiger; David G. Birch; John D. Ash; Alessandro Iannaccone; John G. Flannery; José A. Sahel; Donald J. Zack; Marco A. Zarbin; and the Foundation Fighting Blindness Scientific Advisory Board
TAGS: genes, genetics, retinal degeneration, comprehension, animal model, mutation
Trans. Vis. Sci. Tech.. 2018; 7(4):6. doi: https://doi.org/10.1167/tvst.7.4.6

ARVO Annual Meeting Abstract July 2018

Large-scale Whole-organism Phenotypic Screen Identifies Rod Cell Neuroprotectants Effective in Zebrafish and Mouse Models of Retinitis Pigmentosa

Liyun Zhang; Conan Chen; Jiang Qian; Hongkai Ji; Donald J Zack; Justin Hanes; David Ackerley; Baerbel Rohrer; Jeff S Mumm

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):980. doi:

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Probing the Differentiation of Retinal Ganglion Cells from Human Embryonic Stem Cells with Inducible CRISPR Interference

Physiological and morphological development of human embryonic stem cell derived retinal ganglion cells

Single-cell lineage tracing of developing retinal systems

Development of a Screening Platform that uses Genome Engineered hPSC-Derived OPCs for the Discovery of Remyelination Promoting Compounds

Lysosome dependent mitophagy is critical for human RGC survival which is disrupted in glaucoma-associated Optineurin E50K mutation

Enzymatic disruption of retinal extracellular matrix affects surface topology of transplanted human retinal ganglion cells

Structural incorporation of transplanted human retinal ganglion cell neurites following proteolytic digestion or transgenic disruption of retinal extracellular matrix components

TNFα-Mediated Priming of Mesenchymal Stem Cells Enhances Their Neuroprotective Effect on Retinal Ganglion Cells

Thyroid hormone signaling specifies cone subtypes in human retinal organoids

Methods to improve and quantify retinal integration of transplanted stem cell-derived retinal ganglion cells for optic nerve regeneration

Inhibition of NF-kB signaling modulates epithelial to mesenchymal transition in human stem cell-derived retinal pigment epithelial cells

MAP4K4 and GSK-3 pathways complement DLK/LZK signaling to control cell death and axon degeneration in retinal ganglion cells

Single-cell transcriptomic analysis of human NRL null retinal organoids

Gene regulation dynamics induced by the protein kinase inhibitor, SBJ-051 associated with neuroprotection in light-induced photoreceptor cell death

Neuroprotection of retinal ganglion cells by BMSC-derived exosomes

“Cellular heterogeneity of human stem cell-derived RGCs”

Switching from the proteasomal to the lysosomal pathway for MQC during human RGC differentiation is essential for RGC survival

Proteomic Approaches to Study Cell Death Mechanisms in Human Stem Cell-Derived Retinal Ganglion Cells

Inherited Retinal Degenerations: Current Landscape and Knowledge Gaps

Large-scale Whole-organism Phenotypic Screen Identifies Rod Cell Neuroprotectants Effective in Zebrafish and Mouse Models of Retinitis Pigmentosa

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