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Retinal Cell Biology February 2025

Regional Alterations in Müller Cell Protein Expression in Human and a Rat Model of Geographic Atrophy

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Poonam Naik; D. Scott McLeod; Imran A. Bhutto; Malia M. Edwards
TAGS: age-related macular degeneration, nonexudative, atrophic condition of skin, embryonic lethal mutation, eye, injections, proteins, retina, tissue membrane, glial fibrillary acidic protein, immunohistochemistry
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):21. https://doi.org/10.1167/iovs.66.2.21

Includes: Supplemental Content

Retina January 2025

Fundus Autofluorescence Variation in Geographic Atrophy of Age-Related Macular Degeneration: A Clinicopathologic Correlation

PDF

Christine A. Curcio; Jeffrey D. Messinger; Andreas Berlin; Kenneth R. Sloan; D. Scott McLeod; Malia M. Edwards; Jacques Bijon; K. Bailey Freund
TAGS: age-related macular degeneration, age-related macular degeneration, nonexudative, atrophic condition of skin, atrophy, autofluorescence, drusen, fundus autofluorescence imaging, histology, pathology, clinical, photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):49. https://doi.org/10.1167/iovs.66.1.49

Includes: Multimedia, Supplemental Content

Retina December 2024

The Umbra and the Penumbra: Longitudinal Effects of Geographic Atrophy in AMD on the Outer Choroid by Imaging Analysis and Histopathological Correlation

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Enrico Borrelli; Francesco Cappellani; Jose S. Pulido; Daniel Pauleikhoff; Imran A. Bhutto; D. Scott McLeod; Michele Reibaldi; Malia M. Edwards
TAGS: age-related macular degeneration, nonexudative, choroid, diagnostic imaging, eye, follow-up, histopathology tests, retinal pigment epithelium atrophy, chief complaint
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):2. https://doi.org/10.1167/iovs.65.14.2

ARVO Annual Meeting Abstract June 2024

Investigation of Müller Cell Profiles in Humans and an In-Vivo Model of Geographic Atrophy

POONAM NAIK; Imran Ahmed Bhutto; D. Scott McLeod; Malia Michelle Edwards

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):768.

ARVO Annual Meeting Abstract June 2024

Clinicopathological features of retinal glial and choroidal changes in an eye with multi-focal geographic atrophy.

Malia Michelle Edwards; D. Scott McLeod; Imran Ahmed Bhutto; Jeffrey Messinger; Andreas Berlin; Jacques Bijon; K Bailey Freund; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):763.

ARVO Annual Meeting Abstract June 2024

CRP activates choroidal mast cell degranulation and alterations in retinal pigment epithelial cells

Imran Ahmed Bhutto; Marzieh Moghadas; Shreya Jolly Jolly; D Scott McLeod; Malia Michelle Edwards

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):724.

ARVO Annual Meeting Abstract June 2024

Histology of fundus autofluorescence (FAF) in multifocal geographic atrophy (GA) with thick choroid in age-related macular degeneration (AMD)

Christine A Curcio; Jeffrey Messinger; Andreas Berlin; Malia Michelle Edwards; D. Scott McLeod; Jacques Bijon; K. Bailey Freund

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2284.

Retina February 2024

Histologic and Immunohistochemical Characterization of GA-Like Pathology in the Rat Subretinal Sodium Iodate Model

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Poonam Naik; Rhonda Grebe; Imran A. Bhutto; D. Scott McLeod; Malia M. Edwards
TAGS: atrophic condition of skin, atrophy, eye, immunohistochemistry, injections, iodates, pathology, sodium, tissue membrane, choroid
Trans. Vis. Sci. Tech.. 2024; 13(2):10. https://doi.org/10.1167/tvst.13.2.10

Retinal Cell Biology March 2023

Clinicopathologic Findings in Three Siblings With Geographic Atrophy

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Malia M. Edwards; D. Scott McLeod; Mengxi Shen; Rhonda Grebe; Janet S. Sunness; Imran A. Bhutto; Erin McDonnell; Alexandra M. Pado; Giovanni Gregori; Philip J. Rosenfeld; Gerard A. Lutty
TAGS: atrophy, drusen, eye, retina, relationship - sibling, choroidal neovascularization, chief complaint, pathology, clinical, donors, atrophic condition of skin
Invest. Ophthalmol. Vis. Sci.. 2023; 64(3):2. https://doi.org/10.1167/iovs.64.3.2

Retinal Cell Biology July 2020

Retinal Glial and Choroidal Vascular Pathology in Donors Clinically Diagnosed With Stargardt Disease

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Malia M. Edwards; Vera L. Bonilha; Imran A. Bhutto; Brent A. Bell; D. Scott McLeod; Joe G. Hollyfield; Gerard A. Lutty
TAGS: donors, retina, stargardt's disease, chief complaint, atrophy, diagnostic imaging, pathology, tissue membrane, eye, neuroglia
Invest. Ophthalmol. Vis. Sci.. 2020; 61(8):27. https://doi.org/10.1167/iovs.61.8.27

Includes: Supplemental Content

Special Issue September 2018

An Acute Injury Model for the Phenotypic Characteristics of Geographic Atrophy

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Imran A. Bhutto; Shuntaro Ogura; Rajkumar Baldeosingh; D. Scott McLeod; Gerard A. Lutty; Malia M. Edwards
TAGS: atrophy, injections, phenotype, wounds and injuries, eye, chief complaint, photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2018; 59(4):AMD143-AMD151. https://doi.org/10.1167/iovs.18-24245

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Choriocapillaris dropout in early age-related macular degeneration

Gerard A Lutty; Imran A. Bhutto; Malia Michelle Edwards; D. Scott McLeod

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2435.

Clinical and Epidemiologic Research February 2018

Clinical Age-Specific Seasonal Conjunctivitis Patterns and Their Online Detection in Twitter, Blog, Forum, and Comment Social Media Posts

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Michael S. Deiner; Stephen D. McLeod; James Chodosh; Catherine E. Oldenburg; Cherie A. Fathy; Thomas M. Lietman; Travis C. Porco
TAGS: conjunctivitis, allergic conjunctivitis, electronic medical records
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):910-920. https://doi.org/10.1167/iovs.17-22818

Includes: Supplemental Content

Retinal Cell Biology November 2017

Mast Cell-Derived Tryptase in Geographic Atrophy

PDF

D. Scott McLeod; Imran Bhutto; Malia M. Edwards; Manasee Gedam; Rajkumar Baldeosingh; Gerard A. Lutty
TAGS: atrophy, tryptase, eye, minimally conscious state
Invest. Ophthalmol. Vis. Sci.. 2017; 58(13):5887-5896. https://doi.org/10.1167/iovs.17-22989

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

A Rat Model of RPE Atrophy Resembling Human Geographic Atrophy

Imran Ahmed Bhutto; Siva Pramodh Kambhampati; D Scott McLeod; Malia Edwards; Gerard A Lutty

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2289.

ARVO Annual Meeting Abstract June 2017

Late Onset Infectious Keratitis after Laser in situ Keratomileusis

Megan Law; Stephen D McLeod; Steve Schallhorn; Julie Marie Schallhorn

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3880.

Retinal Cell Biology March 2017

Subretinal Glial Membranes in Eyes With Geographic Atrophy

PDF

Malia M. Edwards; D. Scott McLeod; Imran A. Bhutto; Rhonda Grebe; Maeve Duffy; Gerard A. Lutty
TAGS: atrophic condition of skin, atrophy, embryonic lethal mutation, eye, neuroglia, retina, tissue membrane, vimentin, glial fibrillary acidic protein
Invest. Ophthalmol. Vis. Sci.. 2017; 58(3):1352-1367. https://doi.org/10.1167/iovs.16-21229

Includes: Supplemental Content

Retinal Cell Biology November 2016

Distribution and Quantification of Choroidal Macrophages in Human Eyes With Age-Related Macular Degeneration

PDF

D. Scott McLeod; Imran Bhutto; Malia M. Edwards; Rachel E. Silver; Johanna M. Seddon; Gerard A. Lutty
TAGS: age-related macular degeneration, choroid, eye, hla-dr antigens, macrophages
Invest. Ophthalmol. Vis. Sci.. 2016; 57(14):5843-5855. https://doi.org/10.1167/iovs.16-20049

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract September 2016

Increased choroidal mast cells and their degranulation in age-related macular degeneration

Imran Ahmed Bhutto; D. Scott McLeod; Jing Tian; Rachel E Silver; Johanna M Seddon; Gerard A Lutty

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12)

ARVO Annual Meeting Abstract September 2016

Müller cell processes occupy the subretinal space in geographic atrophy and Stargardt disease.

Malia Michelle Edwards; D. Scott McLeod; Imran Ahmed Bhutto; Rhonda Grebe; Mercedes Villalonga; Vera L Bonilha; Joe G Hollyfield; Johanna M Seddon; Gerard A Lutty

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4191.

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Regional Alterations in Müller Cell Protein Expression in Human and a Rat Model of Geographic Atrophy

Fundus Autofluorescence Variation in Geographic Atrophy of Age-Related Macular Degeneration: A Clinicopathologic Correlation

The Umbra and the Penumbra: Longitudinal Effects of Geographic Atrophy in AMD on the Outer Choroid by Imaging Analysis and Histopathological Correlation

Investigation of Müller Cell Profiles in Humans and an In-Vivo Model of Geographic Atrophy

Clinicopathological features of retinal glial and choroidal changes in an eye with multi-focal geographic atrophy.

CRP activates choroidal mast cell degranulation and alterations in retinal pigment epithelial cells

Histology of fundus autofluorescence (FAF) in multifocal geographic atrophy (GA) with thick choroid in age-related macular degeneration (AMD)

Histologic and Immunohistochemical Characterization of GA-Like Pathology in the Rat Subretinal Sodium Iodate Model

Clinicopathologic Findings in Three Siblings With Geographic Atrophy

Retinal Glial and Choroidal Vascular Pathology in Donors Clinically Diagnosed With Stargardt Disease

An Acute Injury Model for the Phenotypic Characteristics of Geographic Atrophy

Choriocapillaris dropout in early age-related macular degeneration

Clinical Age-Specific Seasonal Conjunctivitis Patterns and Their Online Detection in Twitter, Blog, Forum, and Comment Social Media Posts

Mast Cell-Derived Tryptase in Geographic Atrophy

A Rat Model of RPE Atrophy Resembling Human Geographic Atrophy

Late Onset Infectious Keratitis after Laser in situ Keratomileusis

Subretinal Glial Membranes in Eyes With Geographic Atrophy

Distribution and Quantification of Choroidal Macrophages in Human Eyes With Age-Related Macular Degeneration

Increased choroidal mast cells and their degranulation in age-related macular degeneration

Müller cell processes occupy the subretinal space in geographic atrophy and Stargardt disease.

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