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ARVO Annual Meeting Abstract June 2022

Intercellular material transfer following retinal ganglion cell transplantation

Kevin Yang Zhang; Erika Antuanette Aguzzi; Arumugam Nagalingam; Casey Keuthan; Xiaoli Chang; Donald J Zack; Thomas Vincent Johnson

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1119. doi:

ARVO Annual Meeting Abstract June 2022

Temporal and isoform-specific expression analysis of the multiuse CTBP2/RIBEYE locus in the developing chicken and human retina.

Ray Enke; Devansh Agarwal; Elizabeth Gage; Calvin Chenault; Kameron Washington-Brown; Sarah Szvetecz; Nusrat Jahan; Melissa Kaye Jones; Donald J Zack; Karl J Wahlin

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):496 – A0073. doi:

ARVO Annual Meeting Abstract June 2022

High content screen for small molecules that inhibit epithelial to mesenchymal transition in human stem cell-derived RPE cells

Srinivasa Sripathi; Cynthia Berlinicke; Xitiz Chamling; Rebekah Mikeasky; Yukan Duan; Caire Bell; Ming-Wen Hu; Julien Maruotti; Karl J Wahlin; Jiang Qian; Noriko Esumi; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):683 – F0137. doi:

ARVO Annual Meeting Abstract June 2022

Histone Deacetylase and Myosin Inhibitors Promote Neurite Outgrowth in Injured Retinal Ganglion Cells Derived from Human Pluripotent Stem Cells

Jie Cheng; Shuaizhang Li; Cynthia Berlinicke; Pingwu Zhang; Xiaoli Chang; Derek Stuart Welsbie; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2445 – F0389. doi:

ARVO Annual Meeting Abstract June 2022

Investigating the cell autonomous effects of NF1 mutation on human RGC development and survival

Casey Keuthan; Shuaizhang Li; Pingwu Zhang; Corina Anastasaki; Cynthia Berlinicke; Yuan Zhu; David Gutmann; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3910 – A0112. doi:

ARVO Annual Meeting Abstract June 2022

Improving integration of transplanted human stem cell derived retinal ganglion cells

Erika Antuanette Aguzzi; Kevin Yang Zhang; Arumugam Nagalingam; Xiaoli Chang; Donald J Zack; Thomas Vincent Johnson

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1140. doi:

Special Issue August 2021

Intrinsic Morphologic and Physiologic Development of Human Derived Retinal Ganglion Cells In Vitro

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Michael L. Risner; Silvia Pasini; Xitiz Chamling; Nolan R. McGrady; Jeffrey L. Goldberg; Donald J. Zack; David J. Calkins
TAGS: neurites, physiological development, retinal ganglion cells, voltage, rna, messenger, depolarization, proteins
Trans. Vis. Sci. Tech.. 2021; 10(10):1. doi: https://doi.org/10.1167/tvst.10.10.1

ARVO Annual Meeting Abstract June 2021

Simultaneous single-cell lineage tracing and transcriptomics of the developing mammalian retina

Claire Bell; Weixiang Fang; Stacey Cole; Kathleen Leeper; Cynthia Berlinicke; Pengfei Zhang; Tza-Huei Wang; Hongkai Ji; Reza Kalhor; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2614. doi:

ARVO Annual Meeting Abstract June 2021

The recipient retinal microenvironment regulates structural engraftment of transplanted human stem cell derived retinal ganglion cells in vivo

Thomas Vincent Johnson; Kevin Y Zhang; Arumugam Nagalingam; Xiaoli Chang; Harry A Quigley; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2425. doi:

ARVO Annual Meeting Abstract June 2021

Neuroprotection of transplanted human stem cell derived retinal ganglion cells: advancing cell replacement strategies for optic nerve regeneration

Kevin Y Zhang; Aru Nagalingam; Pingwu Zhang; Xiaoli Chang; Harry A Quigley; Derek S Welsbie; Donald J Zack; Thomas Vincent Johnson

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2376. doi:

ARVO Annual Meeting Abstract June 2021

Glaucomatous Optineurin-E50K mutation causes human retinal ganglion cell death by causing mitophagy defects

Kavitha Anbarasu; Michelle Surma; Kang-Chieh Huang; Jason S Meyer; Donald J Zack; Arupratan Das

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2348. doi:

Biochemistry and Molecular Biology April 2021

Transcriptome Landscape of Epithelial to Mesenchymal Transition of Human Stem Cell–Derived RPE

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Srinivasa R. Sripathi; Ming-Wen Hu; Melissa M. Liu; Jun Wan; Jie Cheng; Yukan Duan; Joseph L. Mertz; Karl J. Wahlin; Julien Maruotti; Cynthia A. Berlinicke; Jiang Qian; Donald J. Zack
TAGS: epithelial to mesenchymal transition, dissociation, tumor necrosis factors, gene expression profiling
Invest. Ophthalmol. Vis. Sci.. 2021; 62(4):1. doi: https://doi.org/10.1167/iovs.62.4.1

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Structural incorporation of transplanted human retinal ganglion cell neurites following proteolytic digestion or transgenic disruption of retinal extracellular matrix components

Thomas Vincent Johnson; Caitlyn Tuffy; Kevin Zhang; Joseph L Mertz; Harry A Quigley; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1163. doi:

ARVO Annual Meeting Abstract June 2020

Probing the Differentiation of Retinal Ganglion Cells from Human Embryonic Stem Cells with Inducible CRISPR Interference

Jie Cheng; Xiaoli Chang; Yukan Duan; Cynthia Berlinicke; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3794. doi:

ARVO Annual Meeting Abstract June 2020

Physiological and morphological development of human embryonic stem cell derived retinal ganglion cells

Michael L Risner; Cathryn Formichella; xitiz chamling; Thomas A Reh; Jeffrey Louis Goldberg; Donald J Zack; David J Calkins

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3871. doi:

ARVO Annual Meeting Abstract June 2020

Single-cell lineage tracing of developing retinal systems

Claire Bell; Weixiang Fang; Cynthia Berlinicke; Aniruddhah Kaushik; Pengfei Zhang; Tza-Huei Wang; Reza Kalhor; Hongkai Ji; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4014. doi:

ARVO Annual Meeting Abstract June 2020

Development of a Screening Platform that uses Genome Engineered hPSC-Derived OPCs for the Discovery of Remyelination Promoting Compounds

xitiz chamling; Cynthia Berlinicke; Yukan Duan; Xiaoli Chang; Peter Calabresi; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5184. doi:

ARVO Annual Meeting Abstract June 2020

Lysosome dependent mitophagy is critical for human RGC survival which is disrupted in glaucoma-associated Optineurin E50K mutation

Arupratan Das; Nicholas Marsh-Armstrong; Jason S Meyer; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):265. doi:

ARVO Annual Meeting Abstract June 2020

Enzymatic disruption of retinal extracellular matrix affects surface topology of transplanted human retinal ganglion cells

Kevin Y Zhang; Caitlyn Tuffy; Joseph L Mertz; Harry A Quigley; Donald J Zack; Thomas Vincent Johnson

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):635. doi:

Visual Neuroscience February 2020

TNFα-Mediated Priming of Mesenchymal Stem Cells Enhances Their Neuroprotective Effect on Retinal Ganglion Cells

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Ben Mead; Xitiz Chamling; Donald J. Zack; Zubair Ahmed; Stanislav Tomarev
TAGS: culture media, conditioned, exosomes, neuroprotection, neuroprotective effect, retinal ganglion cells, stem cell, mesenchymal, cell culture techniques
Invest. Ophthalmol. Vis. Sci.. 2020; 61(2):6. doi: https://doi.org/10.1167/iovs.61.2.6

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Intercellular material transfer following retinal ganglion cell transplantation

Temporal and isoform-specific expression analysis of the multiuse CTBP2/RIBEYE locus in the developing chicken and human retina.

High content screen for small molecules that inhibit epithelial to mesenchymal transition in human stem cell-derived RPE cells

Histone Deacetylase and Myosin Inhibitors Promote Neurite Outgrowth in Injured Retinal Ganglion Cells Derived from Human Pluripotent Stem Cells

Investigating the cell autonomous effects of NF1 mutation on human RGC development and survival

Improving integration of transplanted human stem cell derived retinal ganglion cells

Intrinsic Morphologic and Physiologic Development of Human Derived Retinal Ganglion Cells In Vitro

Simultaneous single-cell lineage tracing and transcriptomics of the developing mammalian retina

The recipient retinal microenvironment regulates structural engraftment of transplanted human stem cell derived retinal ganglion cells in vivo

Neuroprotection of transplanted human stem cell derived retinal ganglion cells: advancing cell replacement strategies for optic nerve regeneration

Glaucomatous Optineurin-E50K mutation causes human retinal ganglion cell death by causing mitophagy defects

Transcriptome Landscape of Epithelial to Mesenchymal Transition of Human Stem Cell–Derived RPE

Structural incorporation of transplanted human retinal ganglion cell neurites following proteolytic digestion or transgenic disruption of retinal extracellular matrix components

Probing the Differentiation of Retinal Ganglion Cells from Human Embryonic Stem Cells with Inducible CRISPR Interference

Physiological and morphological development of human embryonic stem cell derived retinal ganglion cells

Single-cell lineage tracing of developing retinal systems

Development of a Screening Platform that uses Genome Engineered hPSC-Derived OPCs for the Discovery of Remyelination Promoting Compounds

Lysosome dependent mitophagy is critical for human RGC survival which is disrupted in glaucoma-associated Optineurin E50K mutation

Enzymatic disruption of retinal extracellular matrix affects surface topology of transplanted human retinal ganglion cells

TNFα-Mediated Priming of Mesenchymal Stem Cells Enhances Their Neuroprotective Effect on Retinal Ganglion Cells

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