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Physiology and Pharmacology October 2019

Sympathetic Effects of Internal Carotid Nerve Manipulation on Choroidal Vascularity and Related Measures

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Juan-Carlos Martinez-Camarillo; Christine K. Spee; Michael Chen; Anthony Rodriguez; Kiran Nimmagadda; Gloria Paulina Trujillo-Sanchez; David R. Hinton; Alessandra Giarola; Victor Pikov; Arun Sridhar; Mark S. Humayun; Andrew C. Weitz
TAGS: eye, growth factor, neurons, angiogenesis, choroid, inflammatory markers, rats, vascular endothelial growth factor a, electric stimulation
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4303-4309. doi: https://doi.org/10.1167/iovs.18-25613

ARVO Annual Meeting Abstract July 2019

Sustained mitochondrial GSH is critical for retinal protection: characterization of GSH carrier proteins in RPE and protection by increased expression with αB crystallin chaperone peptide.

Mo Wang; LingIng Lau; Parameswaran G Sreekumar; Christine Spee; David R Hinton; Srinivas R Sadda; Ram Kannan

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1715. doi:

ARVO Annual Meeting Abstract July 2019

αB Crystallin Chaperone Peptide (mini Cry) Inhibits Senescence in RPE cells by Modulating Mitochondrial Biogenesis and Fission Proteins

Parameswaran G Sreekumar; David R Hinton; Judith Campisi; Srinivas R Sadda; Ram Kannan

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1950. doi:

ARVO Annual Meeting Abstract July 2019

Co-grafted sheets of hESC derived retina organoids and RPE improve vision function in RCS rats

Bin Lin; Juan Carlos Martinez; Dan Hong Zhu; David R Hinton; Mark Humayun; Bryce McLelland; Robert Aramant; Magdalene J Seiler; Biju Thomas

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2890. doi:

Articles May 2019

Histopathologic Assessment of Optic Nerves and Retina From a Patient With Chronically Implanted Argus II Retinal Prosthesis System

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Tai-Chi Lin; Lei-Chi Wang; Lan Yue; Yi Zhang; Paulo Falabella; Danhong Zhu; David R. Hinton; Narsing A. Rao; David G. Birch; Rand Spencer; Jessy D. Dorn; Mark S. Humayun
TAGS: eye, histopathology tests, implants, optic nerve, retina, visual prosthesis
Trans. Vis. Sci. Tech.. 2019; 8(3):31. doi: https://doi.org/10.1167/tvst.8.3.31

Retinal Cell Biology February 2019

Characterization and Regulation of Carrier Proteins of Mitochondrial Glutathione Uptake in Human Retinal Pigment Epithelium Cells

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Mo Wang; Lin-Ing Lau; Parameswaran G. Sreekumar; Christine Spee; David R. Hinton; Srinivas R. Sadda; Ram Kannan
TAGS: carrier proteins, glutathione, mitochondria, regulation, retinal pigment cell, proteins, retinal pigment epithelium, apoptosis, fluorescent antibody technique, caspase-3
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):500-516. doi: https://doi.org/10.1167/iovs.18-25686

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

CRISPR-Cas9 RNP complex, delivered via lipid nanoparticle, is effective in disruption of RHO gene in vitro

Amirmohsen Arbabi; Christine Spee; David R Hinton; Peter Z. Qin; Cheryl Mae Craft; Sarah F Hamm-Alvarez; Hossein Ameri

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):26. doi:

ARVO Annual Meeting Abstract July 2018

A Complete Retina Patch to Treat Irreversible Retinal Injuries

Biju Thomas; Bryce T McLelland; Danhong Zhu; Gabriel Nistor; Robert B Aramant; David R Hinton; Mark S. Humayun; Hans S Keirstead; Magdalene J Seiler

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):558. doi:

ARVO Annual Meeting Abstract July 2018

Role of mitochondrial ROS in TGF-ß-induced mitochondrial translocation of SMAD4 and its interaction with COXII

Ram Kannan; Parameswaran G Sreekumar; Keijiro Ishikawa; David R Hinton

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4036. doi:

ARVO Annual Meeting Abstract July 2018

αB crystallin peptide fused to elastin-like polypeptide provides long-term neuroprotection in a mouse model of AMD

Parameswaran G Sreekumar; Zhe Li; Wan Wang; Christine Spee; J. Andrew MacKay; David R Hinton; Ram Kannan

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2457. doi:

ARVO Annual Meeting Abstract June 2017

Steroid-Response in Primary Culture Scleral Cells, Implications for Distal Outflow Pathology.

Thania Bogarin; Sindhu Saraswathy; Elizabeth Tannous; Chi Zhang; Jose Gonzalez; James C Tan; David R Hinton; Robert N Weinreb; Jie J Zheng; Alex S Huang

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3480. doi:

ARVO Annual Meeting Abstract June 2017

Aqueous Angiography Based Comparison of High- and Low-Flow Regions for Alpha-Smooth Muscle Actin (α-SMA) and Versican in Post-Mortem Human Eyes.

Sindhu Saraswathy; Thania Bogarin; Chirayu Mohindroo; Brian Alan Francis; James C Tan; David R Hinton; Robert N Weinreb; Alex S Huang

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3479. doi:

ARVO Annual Meeting Abstract June 2017

αB crystallin peptide recombinantly fused with elastin-like polypeptides protects retina from NaIO3-induced RPE atrophy

Parameswaran G Sreekumar; Zhe Li; Wan Wang; Christine Spee; John Andrew MacKay; David R Hinton; Ram Kannan

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1923. doi:

ARVO Annual Meeting Abstract June 2017

Survival and functionality of iPSC-RPE cultured as a polarized monolayer on ultrathin parylene assessed in a new immunodeficient RCS rat model

Biju Thomas; Yousuf Shad; Juan Carlos Martinez; Niharika Singh; Young Chang Kim; Seth Freeman; Sean Anthony Mu; Vishweshwer Shastri; Kapil Bharti; Mark S Humayun; David R Hinton; Danhong Zhu

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3263. doi:

ARVO Annual Meeting Abstract June 2017

Exploring Cytoprotective Molecules for Polarized HESC-RPE Cells

Danhong Zhu; Jon takemoto; Sreekumar Parameswaran; David R Hinton

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4561. doi:

ARVO Annual Meeting Abstract June 2017

The mitochondrial-derived peptide humanin improves mitochondrial bioenergetics after endoplasmic reticulum stress in human RPE cells

Hiroto Terasaki; Parameswaran G Sreekumar; Hemal H Mehta; Pinchas Cohen; David R Hinton; Ram Kannan

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5361. doi:

ARVO Annual Meeting Abstract June 2017

Protective action of a novel HDL mimetic peptide, HM-10/10 in RPE in vitro and in a murine model of sodium iodate induced retinal degeneration

Ram Kannan; Feng Su; Robin Farias-Eisner; Christine Spee; Eric Barron; David R Hinton; Srinivasa T Reddy

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5364. doi:

ARVO Annual Meeting Abstract June 2017

The effects of Pigment Epithelium-Derived Factor on Epithelial-to-mesenchymal transition of the retinal pigment epithelium induced by TGF-β.

Sha Ouyang; Shikun He; Chirstine Spee; David R Hinton

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5977. doi:

Articles November 2016

Aqueous Angiography with Fluorescein and Indocyanine Green in Bovine Eyes

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Alex S. Huang; Sindhu Saraswathy; Anna Dastiridou; Alan Begian; Hanz Legaspi; Chirayu Mohindroo; James C. H. Tan; Brian A. Francis; Joseph Caprioli; David R. Hinton; Robert N. Weinreb
TAGS: angiogram, cattle, eye, fluorescein, indocyanine green
Trans. Vis. Sci. Tech.. 2016; 5(6):5. doi: https://doi.org/10.1167/tvst.5.6.5

ARVO Annual Meeting Abstract September 2016

SD-OCT Assessment of Retinal Structure After Subretinal Implantation of a Substrate-Adherent Monolayer of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium

Ana Martynova; Amir H Kashani; Rodrigo A Brant; Michael Koss; Danhong Zhu; David R Hinton; Dennis O Clegg; Mark S Humayun

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4270. doi:

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Sympathetic Effects of Internal Carotid Nerve Manipulation on Choroidal Vascularity and Related Measures

Sustained mitochondrial GSH is critical for retinal protection: characterization of GSH carrier proteins in RPE and protection by increased expression with αB crystallin chaperone peptide.

αB Crystallin Chaperone Peptide (mini Cry) Inhibits Senescence in RPE cells by Modulating Mitochondrial Biogenesis and Fission Proteins

Co-grafted sheets of hESC derived retina organoids and RPE improve vision function in RCS rats

Histopathologic Assessment of Optic Nerves and Retina From a Patient With Chronically Implanted Argus II Retinal Prosthesis System

Characterization and Regulation of Carrier Proteins of Mitochondrial Glutathione Uptake in Human Retinal Pigment Epithelium Cells

CRISPR-Cas9 RNP complex, delivered via lipid nanoparticle, is effective in disruption of RHO gene in vitro

A Complete Retina Patch to Treat Irreversible Retinal Injuries

Role of mitochondrial ROS in TGF-ß-induced mitochondrial translocation of SMAD4 and its interaction with COXII

αB crystallin peptide fused to elastin-like polypeptide provides long-term neuroprotection in a mouse model of AMD

Steroid-Response in Primary Culture Scleral Cells, Implications for Distal Outflow Pathology.

Aqueous Angiography Based Comparison of High- and Low-Flow Regions for Alpha-Smooth Muscle Actin (α-SMA) and Versican in Post-Mortem Human Eyes.

αB crystallin peptide recombinantly fused with elastin-like polypeptides protects retina from NaIO3-induced RPE atrophy

Survival and functionality of iPSC-RPE cultured as a polarized monolayer on ultrathin parylene assessed in a new immunodeficient RCS rat model

Exploring Cytoprotective Molecules for Polarized HESC-RPE Cells

The mitochondrial-derived peptide humanin improves mitochondrial bioenergetics after endoplasmic reticulum stress in human RPE cells

Protective action of a novel HDL mimetic peptide, HM-10/10 in RPE in vitro and in a murine model of sodium iodate induced retinal degeneration

The effects of Pigment Epithelium-Derived Factor on Epithelial-to-mesenchymal transition of the retinal pigment epithelium induced by TGF-β.

Aqueous Angiography with Fluorescein and Indocyanine Green in Bovine Eyes

SD-OCT Assessment of Retinal Structure After Subretinal Implantation of a Substrate-Adherent Monolayer of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium

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