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ARVO Annual Meeting Abstract June 2020

NGM621 is a Potent Inhibitory Anti-Complement C3 Antibody in Development for Treatment of Geographic Atrophy

Alexander Loktev; Iris Ngan; Kalyani Mondal; Yan Wang; Jian Luo; Darrin Lindhout; Bin Fan; Raj Haldankar; Jie Tang; Husam Younis; David Shen; Hui Tian; Zhonghao Liu

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1798. doi:

ARVO Annual Meeting Abstract June 2020

Efficacy of Complement C3 Inhibition in Preclinical Models of Wet Age-related Macular Degeneration (AMD)

Wei-Sheng Chen; Benbo Song; Mary-Kamala Isoka; Maria Bogachek; Betty Li; Kalyani Mondal; Yan Wang; Serena Leong; Darrin Lindhout; Bin Fan; Raj Haldankar; Jie Tang; David Shen; Hui Tian; Zhonghao Liu; Alexander Loktev

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1799. doi:

ARVO Annual Meeting Abstract July 2019

Age at Glaucoma Diagnosis in Germline Myocilin Mutation Patients: Association with Polymorphisms in Protein Stabilities

Jie J Zheng; Tarin Tanji; Emily Cohen; Darrick Shen; Fei Yu

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5162. doi:

Retinal Cell Biology November 2016

Potential of Small Molecule–Mediated Reprogramming of Rod Photoreceptors to Treat Retinitis Pigmentosa

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Paul A. Nakamura; Shibing Tang; Andy A. Shimchuk; Sheng Ding; Thomas A. Reh
TAGS: dimethyl sulfoxide, mice, photoreceptors, retina, retinitis pigmentosa, rhodopsin, rod photoreceptors, small molecule, retinal cone, genes
Invest. Ophthalmol. Vis. Sci.. 2016; 57(14):6407-6415. doi: https://doi.org/10.1167/iovs.16-20177

ARVO Annual Meeting Abstract September 2016

Manipulating photoreceptor gene expression with putative Nr2e3 modulators

Paul A Nakamura; Shibing Tang; Sheng Ding; Thomas A Reh

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):580. doi:

ARVO Annual Meeting Abstract June 2015

Antibiotic Treatment Exacerbates Focal Retinal Degeneration in a Mouse Model of AMD

Liliana Guedez; Nicholas Popp; DeFen Shen; Haohua Qian; Yichao Li; Chi-Chao Chan

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):276. doi:

Vision Sciences Society Annual Meeting Abstract August 2014

Local Structure Drives Human Scene Categorization: Converging Evidence from Computational Analysis, Behavior, and Neural Decoding

Heeyoung Choo; Dandan Shen; Dirk Walther

Journal of Vision. 2014; 14(10):1124. doi: https://doi.org/10.1167/14.10.1124

ARVO Annual Meeting Abstract April 2014

Characterization of ocular lesions in gp91phox-/- and p47phox-/- mice with ocular pathological features of human chronic granulomatous disease

Yujuan Wang; Emilia L Falcone; Defen Shen; Mones S Abu-Asab; Alexander Ogilvy; Steven M Holland; Chi-Chao Chan

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2868. doi:

ARVO Annual Meeting Abstract April 2014

The involvement of IL-17RC pathway in the inflammatory stimuli of the multipotent retinal stem cells

Shida Chen; Defen Shen; Nicholas Popp; Jingsheng Tuo; Mones S Abu-Asab; Ting Xie; Chi-Chao Chan

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3984. doi:

ARVO Annual Meeting Abstract April 2014

Is There a Relationship Between Extranuclear DNA and Degenerative Mitochondria?

Alexander Ogilvy; De Fen Shen; Chi-Chao Chan; Mones S Abu-Asab

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):6324. doi:

Vision Sciences Society Annual Meeting Abstract July 2013

Viewpoint Independence in Implicit Scene Learning

Zhongting Wang; Shiyi Li; Haibo Yang; Deli Shen; Xuejun Bai; Hong-jin Sun

Journal of Vision. 2013; 13(9):219. doi: https://doi.org/10.1167/13.9.219

Vision Sciences Society Annual Meeting Abstract July 2013

Structural, not spectral properties underlie human categorization of natural scenes

Dirk Walther; Dandan Shen

Journal of Vision. 2013; 13(9):1054. doi: https://doi.org/10.1167/13.9.1054

Vision Sciences Society Annual Meeting Abstract July 2013

The Intrinsic Reference System in Spatial Learning: Evidence from a Contextual Cueing Paradigm

Shiyi Li; Zhongting Wang; Haibo Yang; Deli Shen; Xuejun Bai; Hong-jin Sun

Journal of Vision. 2013; 13(9):1057. doi: https://doi.org/10.1167/13.9.1057

ARVO Annual Meeting Abstract June 2013

NLRP3 inflammasome activation in human retinal pigment epithelium under inflammation and oxidative stress

Yujuan Wang; Mones Abu-Asab; DeFen Shen; Xi Chu; Alexander Ogilvy; Jingsheng Tuo; Chi-Chao Chan

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):149. doi:

ARVO Annual Meeting Abstract June 2013

Inflammasomes in human eyes with AMD and mouse retinas with focal retinal degeneration

Chi-Chao Chan; DeFen Shen; Yujuan Wang; Xi Chu; Mones Abu-Asab; Jingsheng Tuo

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):315. doi:

ARVO Annual Meeting Abstract June 2013

Distinct Profiles of Vitreous micro RNA in Primary Vitreoretinal Lymphoma and Uveitis

Jingsheng Tuo; DeFen Shen; Chi-Chao Chan

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):5881. doi:

ARVO Annual Meeting Abstract June 2013

Using a Murine Xenograft Model for Von Hippel-Lindau Disease-Associated Retinal Hemangioblastomas to Test Novel Therapies

Stanley Park; Yujuan Wang; Kristin Huntoon; DeFen Shen; Zhengping Zhuang; Chi-Chao Chan

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):5882. doi:

ARVO Annual Meeting Abstract June 2013

Gene Expression Profile of Ccl2/Cx3cr1 Double Deficient, Ccl2 Deficient or Cx3cr1 Deficient Mice with or without rd8 Background

De Fen Shen; Yujuan Wang; Jingsheng Tuo; Xi Chu; Chi-Chao Chan

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):140. doi:

ARVO Annual Meeting Abstract June 2013

Adult human RPE has greater susceptibility to IL17A-induced degeneration than fetal human RPE

Xi Chu; Yujuan Wang; De Fen Shen; Alexander Ogilvy; Rong Li; Shayma Jawad; Baoying Liu; Mones Abu-Asab; Jingsheng Tuo; Chi-Chao Chan

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1780. doi:

ARVO Annual Meeting Abstract June 2013

Extranuclear DNA: a Normal Phenomenon or an Indication of Pathology?

Alexander Ogilvy; De Fen Shen; Yujuan Wang; Chi-Chao Chan; Mones Abu-Asab

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1782. doi:

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NGM621 is a Potent Inhibitory Anti-Complement C3 Antibody in Development for Treatment of Geographic Atrophy

Efficacy of Complement C3 Inhibition in Preclinical Models of Wet Age-related Macular Degeneration (AMD)

Age at Glaucoma Diagnosis in Germline Myocilin Mutation Patients: Association with Polymorphisms in Protein Stabilities

Potential of Small Molecule–Mediated Reprogramming of Rod Photoreceptors to Treat Retinitis Pigmentosa

Manipulating photoreceptor gene expression with putative Nr2e3 modulators

Antibiotic Treatment Exacerbates Focal Retinal Degeneration in a Mouse Model of AMD

Local Structure Drives Human Scene Categorization: Converging Evidence from Computational Analysis, Behavior, and Neural Decoding

Characterization of ocular lesions in gp91phox-/- and p47phox-/- mice with ocular pathological features of human chronic granulomatous disease

The involvement of IL-17RC pathway in the inflammatory stimuli of the multipotent retinal stem cells

Is There a Relationship Between Extranuclear DNA and Degenerative Mitochondria?

Viewpoint Independence in Implicit Scene Learning

Structural, not spectral properties underlie human categorization of natural scenes

The Intrinsic Reference System in Spatial Learning: Evidence from a Contextual Cueing Paradigm

NLRP3 inflammasome activation in human retinal pigment epithelium under inflammation and oxidative stress

Inflammasomes in human eyes with AMD and mouse retinas with focal retinal degeneration

Distinct Profiles of Vitreous micro RNA in Primary Vitreoretinal Lymphoma and Uveitis

Using a Murine Xenograft Model for Von Hippel-Lindau Disease-Associated Retinal Hemangioblastomas to Test Novel Therapies

Gene Expression Profile of Ccl2/Cx3cr1 Double Deficient, Ccl2 Deficient or Cx3cr1 Deficient Mice with or without rd8 Background

Adult human RPE has greater susceptibility to IL17A-induced degeneration than fetal human RPE

Extranuclear DNA: a Normal Phenomenon or an Indication of Pathology?

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