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Cornea February 2025

Global MicroRNA Profiling of HSV-1 Infected Cornea Identifies miR-329 as a Novel Regulator of Virus Infection

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Pankaj Sharma; Raza Ali Naqvi; Hemant Borase; Divya Kapoor; Araceli Valverde; Kristelle Capistrano; Tejabhiram Yadavalli; Afsar R. Naqvi; Deepak Shukla
TAGS: human herpesvirus 1, micrornas, cornea, infections, virus diseases
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):61. https://doi.org/10.1167/iovs.66.2.61

Includes: Supplemental Content

Immunology and Microbiology June 2024

Rapid NETosis Is an Effector Mechanism to Combat Ocular Herpes Infection

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Chandrashekhar D. Patil; Hemant Borase; Satyashree Gagan; Pankaj Sharma; Divya Kapoor; Tejabhiram Yadavalli; Sandeep Jain; Joveeta Joseph; Bhupesh Bagga; Deepak Shukla
TAGS: dna, double-stranded, eye, eye infection herpes simplex, eye infections, human herpesvirus 1, infections, keratitis, herpetic, mice, neutrophils, cornea
Invest. Ophthalmol. Vis. Sci.. 2024; 65(6):36. https://doi.org/10.1167/iovs.65.6.36

Includes: Supplemental Content

Anatomy and Pathology/Oncology April 2024

Short-Term Myopic Defocus and Choroidal Thickness in Children and Adults

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Lisa A. Ostrin; Raman P. Sah; Hope M. Queener; Nimesh B. Patel; Raphaella Tran; Divya Shukla; Hanieh Mirhajianmoghadam
TAGS: adult, child, choroid, eye, refractive errors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):22. https://doi.org/10.1167/iovs.65.4.22

Immunology and Microbiology March 2024

Exploring Heparanase Levels in Tears: Insights From Herpes Simplex Virus-1 Keratitis Patients and Animal Studies

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Satyashree Gagan; Agimanailiu Khapuinamai; Divya Kapoor; Pankaj Sharma; Tejabhiram Yadavalli; Joveeta Joseph; Deepak Shukla; Bhupesh Bagga
TAGS: heparanase, herpes simplex infection, human herpesvirus 1, keratitis, mice, mice, inbred c57bl, viruses, simplexvirus, animal testing
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):7. https://doi.org/10.1167/iovs.65.3.7

Includes: Supplemental Content

Immunology and Microbiology November 2023

Unique Attributes of Guinea Pigs as New Models to Study Ocular Herpes Pathophysiology and Recurrence

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Tejabhiram Yadavalli; Chandrashekhar Patil; Pankaj Sharma; Ipsita Volety; Hemant Borase; Divya Kapoor; Deepak Shukla
TAGS: caviidae, guinea, human herpesvirus 1, infections, recurrence, keratitis, herpetic, cornea, oryctolagus cuniculus, pathology, viruses
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):41. https://doi.org/10.1167/iovs.64.14.41

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

New investigational therapies against herpetic infection of the cornea

Deepak Shukla

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2410.

ARVO Annual Meeting Abstract June 2023

Use of a multi-omic approach to drug discovery for the treatment of HSV-1 infection

Tejabhiram Yadavalli; Krishnaraju Madavaraju; Raghuram Koganti; Sudhanshu Kumar Singh; Joshua Ames; Rahul Suryawanshi; Chandrashekhar Devidas Patil; Ilina Bhattacharya; Deepak Shukla

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5185.

ARVO Annual Meeting Abstract June 2023

Expression of Heparan Sulfate degrading Enzyme: Heparanase in tears of patients diagnosed with HSV-1 keratitis

SATYASHREE GAGAN; Agimanailiu Khapuinamai; Tejabhiram Yadavalli; Deepak Shukla; Joveeta Joseph Ruben; Bhupesh Bagga

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2338.

ARVO Annual Meeting Abstract June 2022

Evaluation of ampyrone (4-aminoantipyrine), an activator of the intra-melanosomal domain of human tyrosinase, as a potential therapeutic agent for oculocutaneous albinism type 1B

VIJAY KUMAR KALASKAR; Monika Dolinska; Nathan Coussens; Sunit Dutta; Ighovie F Onojafe; Yingyos Jittayasothorn; Ramakrishna Prasad alur; Dhyanam Shukla; Robin Kee; Maria M Campos; Mones Abu-Asab; Tiziana Cogliati; YURI SERGEEV; Brian Patrick Brooks

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):676 – F0130.

ARVO Annual Meeting Abstract June 2022

Safety, efficacy and delivery of multiple nucleoside analogs via drug encapsulated carbon (DECON) based sustained drug release platform.

Tejabhiram Yadavalli; Joshua Ames; David Wu; Benjamin Ramirez; Navya Bellamkonda; Deepak Shukla

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1093.

ARVO Annual Meeting Abstract June 2021

Optineurin is a novel host defense factor against viral infections of the eye and infection-associated nerve damage

Deepak Shukla; Joshua Ames; Tejabhiram Yadavalli; Rahul K Suryawanshi; James Hopkins; Alex Agelidis; Tibor Valyi-Nagy

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2689.

ARVO Annual Meeting Abstract June 2021

Standardization of multiplex PCR for detection of viral uveitis causative agents

Mark Andrew Solinski; Rahul K Suryawanshi; Ram Koganti; Raman Michael; Neil Shah; Deepak Shukla; Veena R Raiji

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3453.

ARVO Annual Meeting Abstract June 2020

Antiviral efficacy of prodigiosin against corneal herpes simplex virus infection

Chandrashekhar Devidas Patil; Rahul K Suryawanshi; Lulia Koujah; Deepak Shukla

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2982.

ARVO Annual Meeting Abstract July 2019

Heparanase Activation by Cathepsin-L is a Trigger for Pro-Inflammatory and Pro-Angiogenic Conditions in the Cornea during Herpes Stromal Keratitis

Deepak Shukla; Alex Agelidis; James Hopkins

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4628.

ARVO Annual Meeting Abstract July 2018

Targeting Akt phosphorylation by a small molecule inhibitor generates an effective strategy to curb corneal herpes simplex virus type-1 infection

Deepak Shukla; Dinesh Jaishankar

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4931.

ARVO Annual Meeting Abstract July 2018

Heparanase upregulation in human corneal tissues infected with herpes simplex virus type 1

Ann-Marie Lobo; Deepak Shukla

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):513.

ARVO Annual Meeting Abstract June 2017

Antiviral activity of a 45 nucleotide DNA aptamer during HSV-1 infection of the cornea.

Tejabhiram Yadavalli; Neel Thakkar; Dinesh Jaishankar; Alex Agelidis; Deepak Shukla

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3599.

ARVO Annual Meeting Abstract June 2017

Dual role for autophagy in herpes simplex virus infection of the cornea

Deepak Shukla; Neel Thakkar; Dinesh Jaishankar

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3619.

ARVO Annual Meeting Abstract June 2017

Pharmacological inhibition of heparanase blocks release of HSV-1 from corneal epithelium

Alex Agelidis; James Hopkins; Deepak Shukla

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3623.

ARVO Annual Meeting Abstract June 2017

A cyclic anti-heparan sulfate peptide provides protection against primary and recurrent herpes simplex virus-1 (HSV-1) infection of the cornea

Dinesh Jaishankar; Deepak Shukla

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4295.

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Global MicroRNA Profiling of HSV-1 Infected Cornea Identifies miR-329 as a Novel Regulator of Virus Infection

Rapid NETosis Is an Effector Mechanism to Combat Ocular Herpes Infection

Short-Term Myopic Defocus and Choroidal Thickness in Children and Adults

Exploring Heparanase Levels in Tears: Insights From Herpes Simplex Virus-1 Keratitis Patients and Animal Studies

Unique Attributes of Guinea Pigs as New Models to Study Ocular Herpes Pathophysiology and Recurrence

New investigational therapies against herpetic infection of the cornea

Use of a multi-omic approach to drug discovery for the treatment of HSV-1 infection

Expression of Heparan Sulfate degrading Enzyme: Heparanase in tears of patients diagnosed with HSV-1 keratitis

Evaluation of ampyrone (4-aminoantipyrine), an activator of the intra-melanosomal domain of human tyrosinase, as a potential therapeutic agent for oculocutaneous albinism type 1B

Safety, efficacy and delivery of multiple nucleoside analogs via drug encapsulated carbon (DECON) based sustained drug release platform.

Optineurin is a novel host defense factor against viral infections of the eye and infection-associated nerve damage

Standardization of multiplex PCR for detection of viral uveitis causative agents

Antiviral efficacy of prodigiosin against corneal herpes simplex virus infection

Heparanase Activation by Cathepsin-L is a Trigger for Pro-Inflammatory and Pro-Angiogenic Conditions in the Cornea during Herpes Stromal Keratitis

Targeting Akt phosphorylation by a small molecule inhibitor generates an effective strategy to curb corneal herpes simplex virus type-1 infection

Heparanase upregulation in human corneal tissues infected with herpes simplex virus type 1

Antiviral activity of a 45 nucleotide DNA aptamer during HSV-1 infection of the cornea.

Dual role for autophagy in herpes simplex virus infection of the cornea

Pharmacological inhibition of heparanase blocks release of HSV-1 from corneal epithelium

A cyclic anti-heparan sulfate peptide provides protection against primary and recurrent herpes simplex virus-1 (HSV-1) infection of the cornea

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