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ARVO Annual Meeting Abstract September 2016

Long-term photoreceptor rescue in two rodent models of retinitis pigmentosa by adeno-associated virus delivery of Stanniocalcin-1

Gavin W Roddy; Douglas Yasumura; Michael Matthes; Marcel Victor Alavi; Sanford L. Boye; Michael P Fautsch; William W Hauswirth; Matthew LaVail

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2737.

Retinal Cell Biology October 2015

In Vivo Visualization of Endoplasmic Reticulum Stress in the Retina Using the ERAI Reporter Mouse

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Marcel V. Alavi; Wei-Chieh Chiang; Heike Kroeger; Douglas Yasumura; Michael T. Matthes; Takao Iwawaki; Matthew M. LaVail; Douglas B. Gould; Jonathan H. Lin
TAGS: endoplasmic reticulum, mice, retina, stress, fluorescence, ophthalmoscopy, proteins, eye
Invest. Ophthalmol. Vis. Sci.. 2015; 56(11):6961-6970. https://doi.org/10.1167/iovs.15-16969

Includes: Supplemental Content

Biochemistry and Molecular Biology October 2015

Allele-Specific Inhibition of Rhodopsin With an Antisense Oligonucleotide Slows Photoreceptor Cell Degeneration

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Susan F. Murray; Ali Jazayeri; Michael T. Matthes; Douglas Yasumura; Haidong Yang; Raechel Peralta; Andy Watt; Sue Freier; Gene Hung; Peter S. Adamson; Shuling Guo; Brett P. Monia; Matthew M. LaVail; Michael L. McCaleb
TAGS: alleles, antisense oligonucleotides, eye, mice, photoreceptors, rhodopsin, tissue degeneration, injections, painful bladder syndrome, rna
Invest. Ophthalmol. Vis. Sci.. 2015; 56(11):6362-6375. https://doi.org/10.1167/iovs.15-16400

ARVO Annual Meeting Abstract June 2015

An Expression Quantitative Trait Locus Modifies Mertk -Associated Retinal Degeneration

Douglas Vollrath; Douglas Yasumura; Wei Feng; Michael Matthes; Gillie Ben-Chorin; Natalie Nguyen; Cecilia Sedano; Melissa Ann Calton; Matthew M LaVail

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4347.

ARVO Annual Meeting Abstract June 2015

Melanopsin expression in the cornea

Shawntay Chaney; Anton Delwig; Andrea Bertke; Todd P Margolis; Douglas Yasumura; Ethan Buhr; Russell Van Gelder; Laura Cammas; David R Copenhagen

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4913.

ARVO Annual Meeting Abstract April 2014

Cellular ceramide acts as 2nd messenger mediating photoreceptor cell death in mammalian retinal degeneration

Nawajes Ali Mandal; Megan Stiles; Eleanor Sun; Tuan-Phat Huynh; Jeremy Tan; Douglas Yasumura; Michael T Matthes; Matthew M LaVail

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1256.

ARVO Annual Meeting Abstract April 2014

Prevention of photoreceptor cell degeneration in P23H rats after allele-specific knockdown of mutant Rhodopsin RNA expression using antisense oligonucleotide (ASO) treatment

Sue F Murray; Ali Jazayeri; Matthew M LaVail; Michael T Matthes; Douglas Yasumura; Haidong Yang; Michael McCaleb; Raechel Peralta; Andy Watt; Brett Monia

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1258.

ARVO Annual Meeting Abstract April 2014

Endoplasmic Reticulum-Associated Degradation (ERAD) of Mutant Rod Opsin Disrupts Photoreceptor Protein Homeostasis During Retinal Degeneration

Wei-Chieh Chiang; Heike Kroeger; Carissa Messah; Douglas Yasumura; Michael T Matthes; Sanae Sakami; Krzysztof Palczewski; Matthew M LaVail; Jonathan H Lin

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1742.

ARVO Annual Meeting Abstract April 2014

Quantitative High Throughput Screening for Small Molecules That Promote Photoreceptor Differentiation and Survival

John A Fuller; Karl Wahlin; Cynthia Berlinicke; Douglas Yasumura; Michael T Matthes; Ryan MacArthur; Patricia Dranchak; Matthew M LaVail; James Inglese; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1911.

ARVO Annual Meeting Abstract April 2014

IRE1 Signaling and ER Stress Levels Increase With Age in Retina

Marcel Victor Alavi; Wei-Chieh Chiang; Heike Kroeger; Douglas Yasumura; Michael T Matthes; Matthew M LaVail; Douglas B Gould; Jonathan H Lin

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4565.

Retinal Cell Biology November 2012

Induction of Endoplasmic Reticulum Stress Genes, BiP and Chop , in Genetic and Environmental Models of Retinal Degeneration

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Heike Kroeger; Carissa Messah; Kelly Ahern; Jason Gee; Victory Joseph; Michael T. Matthes; Douglas Yasumura; Marina S. Gorbatyuk; Wei-Chieh Chiang; Matthew M. LaVail; Jonathan H. Lin
TAGS: cyclophosphamide, doxorubicin, prednisone, and vincristine, retinal degeneration, stress, genes, genetics, endoplasmic reticulum, rhodopsin, rats, retina
Invest. Ophthalmol. Vis. Sci.. 2012; 53(12):7590-7599. https://doi.org/10.1167/iovs.12-10221

Includes: Supplemental Content

Visual Psychophysics and Physiological Optics September 2012

Discordant Anatomical, Electrophysiological, and Visual Behavioral Profiles of Retinal Degeneration in Rat Models of Retinal Degenerative Disease

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Trevor J. McGill; Glen T. Prusky; Robert M. Douglas; Douglas Yasumura; Michael T. Matthes; Robert J. Lowe; Jacque L. Duncan; Haidong Yang; Kelly Ahern; Kate M. Daniello; Byron Silver; Matthew M. LaVail
TAGS: degenerative disorders, electroretinography, photoreceptors, rats, retinal degeneration, rhodopsin, tissue degeneration, vision
Invest. Ophthalmol. Vis. Sci.. 2012; 53(10):6232-6244. https://doi.org/10.1167/iovs.12-9569

Retina April 2012

Tyrosine-Mutant AAV8 Delivery of Human MERTK Provides Long-Term Retinal Preservation in RCS Rats

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Wen-Tao Deng; Astra Dinculescu; Qiuhong Li; Sanford L. Boye; Jie Li; Marina S. Gorbatyuk; Jijing Pang; Vince A. Chiodo; Michael T. Matthes; Douglas Yasumura; Li Liu; Fowzan S. Alkuraya; Kang Zhang; Douglas Vollrath; Matthew M. LaVail; William W. Hauswirth
TAGS: eye, mertk gene, rats, tyrosine, retina, photoreceptors, spatial vectors, did not receive therapy or drug
Invest. Ophthalmol. Vis. Sci.. 2012; 53(4):1895-1904. https://doi.org/10.1167/iovs.11-8831

Includes: Supplemental Content

ARVO Annual Meeting Abstract March 2012

Endoplasmic Reticulum Stress In Environmental And Genetic Models Of Retinal Degeneration

Jonathan H. Lin; Heike Kroeger; Carissa Messah; Kelly Ahern; Jason Gee; Victory Joseph; Michael T. Matthes; Douglas Yasumura; Marina S. Gorbatyuk; Matthew M. LaVail

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):4275.

ARVO Annual Meeting Abstract April 2011

Intravitreal Administration Of Adult Stem/progenitor Cells And Their Secreted Proteins Delays Retinal Degeneration By Decreasing Apoptosis In Two Rat Models

Gavin W. Roddy; Robert H. Rosa, Jr.; Matthew M. LaVail; Michael T. Matthes; Douglas Yasumura; Joo Youn Oh; Darwin J. Prockop

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2218.

ARVO Annual Meeting Abstract April 2011

mTOR-Mediated Dedifferentiation of the RPE Initiates Photoreceptor Degeneration

Douglas Vollrath; Chen Zhao; Douglas Yasumura; Xiyan Li; Michael Matthes; Michael Snyder; Dean Bok; Joshua Dunaief; Matthew LaVail

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):4785.

ARVO Annual Meeting Abstract April 2010

Control of Müller Glial Cell Morphology by Focal Adhesion Kinase Impacts Visual Function in Mice

H. E. Beggs; C. Bouquet; G. Lambright; H. Yang; G. Nielsen; D. Yasumura; M. T. Matthes; J. L. Duncan; M. M. LaVail

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):1901.

ARVO Annual Meeting Abstract April 2010

Deletion of Focal Adhesion Kinase From the Retinal Pigment Epithelium Results in Progressive Retinal Degeneration in Mice

B. T. Pawlikowski; C. Bouquet; H. Yang; G. Nielsen; D. Yasumura; M. Matthes; J. L. Duncan; P. Chambon; M. M. LaVail; H. Beggs

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):5203.

ARVO Annual Meeting Abstract April 2010

Suppression of rds Expression by siRNA and Gene Replacement Strategies for Gene Therapy Using AAV Vector

H. Petrs-Silva; D. Yasumura; M. Matthes; M. LaVail; W. W. Hauswirth; A. Lewin

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):5336.

ARVO Annual Meeting Abstract April 2009

Chop Expression in Transgenic Animal Models of Retinal Degeneration

J. H. Lin; J. Kim; M. S. Gorbatyuk; K. Ahern; M. T. Matthes; D. Yasumura; A. S. Lewin; M. M. LaVail

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):4466.

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Long-term photoreceptor rescue in two rodent models of retinitis pigmentosa by adeno-associated virus delivery of Stanniocalcin-1

In Vivo Visualization of Endoplasmic Reticulum Stress in the Retina Using the ERAI Reporter Mouse

Allele-Specific Inhibition of Rhodopsin With an Antisense Oligonucleotide Slows Photoreceptor Cell Degeneration

An Expression Quantitative Trait Locus Modifies Mertk -Associated Retinal Degeneration

Melanopsin expression in the cornea

Cellular ceramide acts as 2nd messenger mediating photoreceptor cell death in mammalian retinal degeneration

Prevention of photoreceptor cell degeneration in P23H rats after allele-specific knockdown of mutant Rhodopsin RNA expression using antisense oligonucleotide (ASO) treatment

Endoplasmic Reticulum-Associated Degradation (ERAD) of Mutant Rod Opsin Disrupts Photoreceptor Protein Homeostasis During Retinal Degeneration

Quantitative High Throughput Screening for Small Molecules That Promote Photoreceptor Differentiation and Survival

IRE1 Signaling and ER Stress Levels Increase With Age in Retina

Induction of Endoplasmic Reticulum Stress Genes, BiP and Chop , in Genetic and Environmental Models of Retinal Degeneration

Discordant Anatomical, Electrophysiological, and Visual Behavioral Profiles of Retinal Degeneration in Rat Models of Retinal Degenerative Disease

Tyrosine-Mutant AAV8 Delivery of Human MERTK Provides Long-Term Retinal Preservation in RCS Rats

Endoplasmic Reticulum Stress In Environmental And Genetic Models Of Retinal Degeneration

Intravitreal Administration Of Adult Stem/progenitor Cells And Their Secreted Proteins Delays Retinal Degeneration By Decreasing Apoptosis In Two Rat Models

mTOR-Mediated Dedifferentiation of the RPE Initiates Photoreceptor Degeneration

Control of Müller Glial Cell Morphology by Focal Adhesion Kinase Impacts Visual Function in Mice

Deletion of Focal Adhesion Kinase From the Retinal Pigment Epithelium Results in Progressive Retinal Degeneration in Mice

Suppression of rds Expression by siRNA and Gene Replacement Strategies for Gene Therapy Using AAV Vector

Chop Expression in Transgenic Animal Models of Retinal Degeneration

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