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Retina August 2022

Identification of Novel Retinal Pericyte-Targeting rAAV Vectors Through Directed Evolution

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Dwani D. Patel; Damien Marsic; Ramesh Periasamy; Sergei Zolotukhin; Daniel M. Lipinski
TAGS: capsid, pericytes, spatial vectors, libraries
Trans. Vis. Sci. Tech.. 2022; 11(8):28. doi: https://doi.org/10.1167/tvst.11.8.28

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Determining the cellular transduction efficacy of multiple rAAV vectors in the murine retina

Rachel Fehrman; Daniel M Lipinski

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):70 – A0043. doi:

ARVO Annual Meeting Abstract June 2022

Improving retinal vascular endothelial cell tropism through rational rAAV capsid design.

Ramesh Periasamy; Dwani D Patel; Sanford L Boye; Shannon E Boye; Daniel M Lipinski

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):66 – A0039. doi:

ARVO Annual Meeting Abstract June 2022

Safety and efficacy of recombinant adeno-associated virus (rAAV) mediated transduction in the anterior chamber of the African Green Monkey ( Chlorocebus sabaeus )

Kristina J Chern; Gavin J Marcoe; Kimica Isaac; Zendorf Gumbs; Dexter Fahie; Melissa O'Conner; Daniel M Lipinski

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):59 – A0032. doi:

ARVO Annual Meeting Abstract June 2022

Exploring the survival of transplanted hiPSC-derived photoreceptors in the 13-lined ground squirrel

Ching Tzu Yu; Sangeetha Kandoi; Ramesh Periasamy; Hannah M Follett; Phyllis Summerfelt; Chloe Guillaume; Owen Bowie; Nicole Manfredonia; Dana Merriman; Thomas B Connor; Daniel M Lipinski; Joseph Carroll; Deepak A Lamba

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1113. doi:

ARVO Annual Meeting Abstract June 2022

Characterization of a primary porcine RPE ‘drusen in a dish’ cell culture model

Erika Shaw; Daniel M Lipinski

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3160 – F0434. doi:

Articles August 2021

Development of a Preclinical Laser Speckle Contrast Imaging Instrument for Assessing Systemic and Retinal Vascular Function in Small Rodents

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Dwani D. Patel; Al-Hafeez Dhalla; Christian Viehland; Thomas B. Connor; Daniel M. Lipinski
TAGS: laser speckle contrast imaging, diagnostic imaging, rodentia, mice
Trans. Vis. Sci. Tech.. 2021; 10(9):19. doi: https://doi.org/10.1167/tvst.10.9.19

ARVO Annual Meeting Abstract June 2021

rAAV-mediated ASAH1 overexpression prevents retinal degeneration in Farber disease

Hanmeng Zhang; Murtaza S Nagree; Jeffrey A Medin; Daniel M Lipinski

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3064. doi:

ARVO Annual Meeting Abstract June 2021

Optimizing transfection and transduction-based gene delivery in primary and immortalized RPE cells

Erika Shaw; Daniel M Lipinski

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2696. doi:

ARVO Annual Meeting Abstract June 2021

Tolerability and efficacy of a rAAV-mediated glaucoma gene therapy in brown norway rats

Kristina J Ertel; Nathan W Li; Emily R Nettesheim; Christopher A Reid; Daniel M Lipinski

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1477. doi:

ARVO Annual Meeting Abstract June 2021

Development of rAAV capsid mutant vectors with improved tropism for retinal vascular endothelial.

Ramesh Periasamy; Dwani Patel; Shannon E Boye; Sanford L Boye; Daniel M Lipinski

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1468. doi:

ARVO Annual Meeting Abstract June 2020

Multimodal retinal imaging of the lined-seahorse (Hippocampus erectus) - a potential model for studying macular disease

Erika Shaw; Ross F Collery; Daniel M Lipinski

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):193. doi:

ARVO Annual Meeting Abstract June 2020

Targeting Retinal Vascular Endothelial cells using rAAV Capsid Mutant Vectors

Ramesh Periasamy; Dwani Patel; Benyapa Khowpinitchai; Shannon Boye; Sanford Boye; Daniel M Lipinski

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4480. doi:

Retina June 2020

Electroretinogram of the Cone-Dominant Thirteen-Lined Ground Squirrel during Euthermia and Hibernation in Comparison with the Rod-Dominant Brown Norway Rat

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Hanmeng Zhang; Benjamin S. Sajdak; Dana K. Merriman; Maureen A. McCall; Joseph Carroll; Daniel M. Lipinski
TAGS: electroretinography, hibernating myocardium, rats, inbred bn, retinal cone, rod photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2020; 61(6):6. doi: https://doi.org/10.1167/iovs.61.6.6

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Intravitreal Delivery of rAAV2 Vectors to the 13-Lined Ground Squirrel Retina

Benjamin S Sajdak; Kristina J. Ertel; Hanmeng Zhang; Emily R. Nettesheim; Dana K. Merriman; Daniel M. Lipinski; Joseph Carroll

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2896. doi:

ARVO Annual Meeting Abstract July 2019

Biodistribution and tolerability of rAAV vectors in the anterior chamber for the treatment of primary open angle glaucoma

Kristina Ertel; Daniel M. Lipinski

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2922. doi:

ARVO Annual Meeting Abstract July 2019

Role of presynaptic LRIT3 expression in the restoration of dim light vision

Nazarul Hasan; gobinda Pangeni; Catherine Cobb; Emily R. Nettesheim; Daniel M. Lipinski; Maureen A McCall; Ronald G Gregg

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4788. doi:

ARVO Annual Meeting Abstract July 2019

A comparison of the electroretinogram in the cone-dominant thirteen-lined ground squirrel and the rod-dominant Brown Norway rat

Hanmeng Zhang; Benjamin S Sajdak; Dana K. Merriman; Joseph Carroll; Maureen A McCall; Daniel M. Lipinski

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5971. doi:

ARVO Annual Meeting Abstract July 2019

Validating Laser Speckle Contrast Imaging as a Quantitative Tool for Measuring Retinal Vascular Function in Rodents

Dwani Patel; Thomas B. Connor; Daniel M. Lipinski

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):172. doi:

Retina October 2018

A Destabilizing Domain Allows for Fast, Noninvasive, Conditional Control of Protein Abundance in the Mouse Eye – Implications for Ocular Gene Therapy

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Shyamtanu Datta; Marian Renwick; Viet Q. Chau; Fang Zhang; Emily R. Nettesheim; Daniel M. Lipinski; John D. Hulleman
TAGS: dihydrofolate reductase, eye, gene therapy, mice, proteins, retina, potable water, regulation, visual acuity
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):4909-4920. doi: https://doi.org/10.1167/iovs.18-24987

Includes: Supplemental Content

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Identification of Novel Retinal Pericyte-Targeting rAAV Vectors Through Directed Evolution

Determining the cellular transduction efficacy of multiple rAAV vectors in the murine retina

Improving retinal vascular endothelial cell tropism through rational rAAV capsid design.

Safety and efficacy of recombinant adeno-associated virus (rAAV) mediated transduction in the anterior chamber of the African Green Monkey ( Chlorocebus sabaeus )

Exploring the survival of transplanted hiPSC-derived photoreceptors in the 13-lined ground squirrel

Characterization of a primary porcine RPE ‘drusen in a dish’ cell culture model

Development of a Preclinical Laser Speckle Contrast Imaging Instrument for Assessing Systemic and Retinal Vascular Function in Small Rodents

rAAV-mediated ASAH1 overexpression prevents retinal degeneration in Farber disease

Optimizing transfection and transduction-based gene delivery in primary and immortalized RPE cells

Tolerability and efficacy of a rAAV-mediated glaucoma gene therapy in brown norway rats

Development of rAAV capsid mutant vectors with improved tropism for retinal vascular endothelial.

Multimodal retinal imaging of the lined-seahorse (Hippocampus erectus) - a potential model for studying macular disease

Targeting Retinal Vascular Endothelial cells using rAAV Capsid Mutant Vectors

Electroretinogram of the Cone-Dominant Thirteen-Lined Ground Squirrel during Euthermia and Hibernation in Comparison with the Rod-Dominant Brown Norway Rat

Intravitreal Delivery of rAAV2 Vectors to the 13-Lined Ground Squirrel Retina

Biodistribution and tolerability of rAAV vectors in the anterior chamber for the treatment of primary open angle glaucoma

Role of presynaptic LRIT3 expression in the restoration of dim light vision

A comparison of the electroretinogram in the cone-dominant thirteen-lined ground squirrel and the rod-dominant Brown Norway rat

Validating Laser Speckle Contrast Imaging as a Quantitative Tool for Measuring Retinal Vascular Function in Rodents

A Destabilizing Domain Allows for Fast, Noninvasive, Conditional Control of Protein Abundance in the Mouse Eye – Implications for Ocular Gene Therapy

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