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Glaucoma August 2020

Aqueous Humor Outflow Requires Active Cellular Metabolism in Mice

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Ester Reina-Torres; Alexandra Boussommier-Calleja; Joseph M. Sherwood; Darryl R. Overby
TAGS: aqueous humor, body temperature, eye, metabolism, mice, temperature
Invest. Ophthalmol. Vis. Sci.. 2020; 61(10):45. doi: https://doi.org/10.1167/iovs.61.10.45

Glaucoma May 2020

Age and Menopause Effects on Ocular Compliance and Aqueous Outflow

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Andrew J. Feola; Joseph M. Sherwood; Machelle T. Pardue; Darryl R. Overby; C. Ross Ethier
TAGS: glaucoma, menopause
Invest. Ophthalmol. Vis. Sci.. 2020; 61(5):16. doi: https://doi.org/10.1167/iovs.61.5.16

Glaucoma March 2020

The β 4 -Subunit of the Large-Conductance Potassium Ion Channel K Ca 1.1 Regulates Outflow Facility in Mice

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Jacques A. Bertrand; Martin Schicht; W. Daniel Stamer; David Baker; Joseph M. Sherwood; Elke Lütjen-Drecoll; David L. Selwood; Darryl R. Overby
TAGS: mice, potassium channel, eye
Invest. Ophthalmol. Vis. Sci.. 2020; 61(3):41. doi: https://doi.org/10.1167/iovs.61.3.41

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Elevated IOP increases Shear Stress in Schlemm’s Canal

Fiona McDonnell; Kristin Marie Perkumas; Nicole E. Ashpole; Joan Kalnitsky; Joseph M Sherwood; Darryl R Overby; W Daniel Stamer

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3181. doi:

ARVO Annual Meeting Abstract July 2019

Aqueous humour outflow requires active cellular metabolism

Ester Reina Torres; Joseph M Sherwood; Darryl R Overby

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5155. doi:

ARVO Annual Meeting Abstract July 2019

Blockade of the BK- a / β 4 potassium ion channel reduces outflow facility in mice

Jacques Alexander Bertrand; Joseph M Sherwood; Martin Schicht; Elke Lütjen-Drecoll; David Selwood; William D Stamer; Darryl R Overby

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5214. doi:

ARVO Annual Meeting Abstract July 2019

Actomyosin contractility and the vimentin cytoskeleton influence giant vacuole life-cycle in Schlemm’s canal endothelial cells

Darryl R Overby; Alice Spenlehauer; Andrea Cairoli; Joseph M Sherwood; Amir Vahabikashi; W Daniel Stamer; Chiu Fan Lee

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5122. doi:

ARVO Annual Meeting Abstract July 2018

INDUCIBLE MMP-3 EXPRESSION IN A STEROID-INDUCED MURINE MODEL OF GLAUCOMA

Jeffrey O'Callaghan; Paul S. Cassidy; Ester Reina-Torres; Joseph Sherwood; Marian M Humphries; Matthew Campbell; Colm J O'Brien; Elke Lütjen-Drecoll; W Daniel Stamer; Darryl R Overby; Peter Humphries

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3505. doi:

ARVO Annual Meeting Abstract July 2018

DISTAL OUTFLOW RESISTANCE CAN BE REGULATED PHARMACOLOGICALLY

Fiona McDonnell; W. Michael Dismuke; Darryl R Overby; W Daniel Stamer

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6039. doi:

ARVO Annual Meeting Abstract July 2018

Impact of Estrogen Deficiency on Outflow Facility and Ocular Biomechanics in Rats

Andrew Feola; Joseph Sherwood; Darryl R Overby; Machelle T Pardue; C Ross Ethier

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1217. doi:

ARVO Annual Meeting Abstract July 2018

The effect of Ultrasound cycloplasty (UCP) using High Intensity Focused Ultrasound (HiFU) on aqueous humor dynamics

Pouya Alaghband; Elizabeth Angela P Galvis; Michael Madekurozwa; Esmail Eslah; Brian Chu; Darryl R Overby; K Sheng Lim

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1648. doi:

ARVO Annual Meeting Abstract July 2018

Modulation of outflow facility by the ocular pulse

Darryl R Overby; Michael Madekurozwa; W Daniel Stamer; Joseph Sherwood

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3971. doi:

Glaucoma November 2017

Effect of Cromakalim Prodrug 1 (CKLP1) on Aqueous Humor Dynamics and Feasibility of Combination Therapy With Existing Ocular Hypotensive Agents

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Uttio Roy Chowdhury; Tommy A. Rinkoski; Cindy K. Bahler; J. Cameron Millar; Jacques A. Bertrand; Bradley H. Holman; Joseph M. Sherwood; Darryl R. Overby; Kristen L. Stoltz; Peter I. Dosa; Michael P. Fautsch
TAGS: antihypertensive agents, aqueous humor, combined modality therapy, cromakalim, eye, intraocular pressure, mice, oryctolagus cuniculus, prodrugs, perfusion
Invest. Ophthalmol. Vis. Sci.. 2017; 58(13):5731-5742. doi: https://doi.org/10.1167/iovs.17-22538

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

A Method to Expose the Inner Wall of Schlemm’s Canal in Mice

A Thomas Read; Darryl R Overby; C Ross Ethier

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1064. doi:

ARVO Annual Meeting Abstract June 2017

Stretch-Dependent Pore Formation in Glaucomatous Schlemm’s Canal Cells

Darryl R Overby; Sietse Braakman; Alice Spenlehauer; Justino R Rodrigues; Carter Teal; A Thomas Read; W Daniel Stamer; C Ross Ethier

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3773. doi:

ARVO Annual Meeting Abstract June 2017

Comparison of Pressure-Dependent Facility in Rodent Eyes

Michael Madekurozwa; Andrew Feola; C Ross Ethier; Darryl R Overby; Joseph Sherwood

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1060. doi:

ARVO Annual Meeting Abstract June 2017

Factors affecting oscillatory shear stress in Schlemm's canal

Joseph Michael Sherwood; W Daniel Stamer; Darryl R Overby

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2454. doi:

Physiology and Pharmacology June 2017

VEGF as a Paracrine Regulator of Conventional Outflow Facility

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Ester Reina-Torres; Joanne C. Wen; Katy C. Liu; Guorong Li; Joseph M. Sherwood; Jason Y. H. Chang; Pratap Challa; Cassandra M. Flügel-Koch; W. Daniel Stamer; R. Rand Allingham; Darryl R. Overby
TAGS: vascular endothelial growth factor a, vascular endothelial growth factor receptor-2, paracrine
Invest. Ophthalmol. Vis. Sci.. 2017; 58(3):1899-1908. doi: https://doi.org/10.1167/iovs.16-20779

Includes: Supplemental Content

Physiology and Pharmacology May 2017

Intravitreal Anti-VEGF Injections Reduce Aqueous Outflow Facility in Patients With Neovascular Age-Related Macular Degeneration

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Joanne C. Wen; Ester Reina-Torres; Joseph M. Sherwood; Pratap Challa; Katy C. Liu; Guorong Li; Jason Y. H. Chang; Scott W. Cousins; Stefanie G. Schuman; Priyatham S. Mettu; W. Daniel Stamer; Darryl R. Overby; R. Rand Allingham
TAGS: exudative age-related macular degeneration, injections, intraocular pressure, eye, ocular hypertension
Invest. Ophthalmol. Vis. Sci.. 2017; 58(3):1893-1898. doi: https://doi.org/10.1167/iovs.16-20786

ARVO Annual Meeting Abstract September 2016

Sustained local delivery of dexamethasone using nanoparticles for steroid-induced ocular hypertension in mice

Jacques Alexander Bertrand; Joseph Michael Sherwood; Guorong Li; W Daniel Stamer; Darryl R Overby

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4706. doi:

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Aqueous Humor Outflow Requires Active Cellular Metabolism in Mice

Age and Menopause Effects on Ocular Compliance and Aqueous Outflow

The β 4 -Subunit of the Large-Conductance Potassium Ion Channel K Ca 1.1 Regulates Outflow Facility in Mice

Elevated IOP increases Shear Stress in Schlemm’s Canal

Aqueous humour outflow requires active cellular metabolism

Blockade of the BK- a / β 4 potassium ion channel reduces outflow facility in mice

Actomyosin contractility and the vimentin cytoskeleton influence giant vacuole life-cycle in Schlemm’s canal endothelial cells

INDUCIBLE MMP-3 EXPRESSION IN A STEROID-INDUCED MURINE MODEL OF GLAUCOMA

DISTAL OUTFLOW RESISTANCE CAN BE REGULATED PHARMACOLOGICALLY

Impact of Estrogen Deficiency on Outflow Facility and Ocular Biomechanics in Rats

The effect of Ultrasound cycloplasty (UCP) using High Intensity Focused Ultrasound (HiFU) on aqueous humor dynamics

Modulation of outflow facility by the ocular pulse

Effect of Cromakalim Prodrug 1 (CKLP1) on Aqueous Humor Dynamics and Feasibility of Combination Therapy With Existing Ocular Hypotensive Agents

A Method to Expose the Inner Wall of Schlemm’s Canal in Mice

Stretch-Dependent Pore Formation in Glaucomatous Schlemm’s Canal Cells

Comparison of Pressure-Dependent Facility in Rodent Eyes

Factors affecting oscillatory shear stress in Schlemm's canal

VEGF as a Paracrine Regulator of Conventional Outflow Facility

Intravitreal Anti-VEGF Injections Reduce Aqueous Outflow Facility in Patients With Neovascular Age-Related Macular Degeneration

Sustained local delivery of dexamethasone using nanoparticles for steroid-induced ocular hypertension in mice

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