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ARVO Annual Meeting Abstract June 2022

The effect of L-NAME on outflow facility in whole porcine eyes.

Ruth A Kelly; Fiona S McDonnell; Darryl R Overby; William Daniel Stamer

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1290 – F0105. doi:

ARVO Annual Meeting Abstract June 2022

The relationship between pressure-dependent changes in outflow facility and dimensional changes in the anterior segment during perfusion of enucleated mouse eyes

Ester Reina-Torres; Joseph van Batenburg-Sherwood; Darryl R Overby

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3301 – A0401. doi:

ARVO Annual Meeting Abstract June 2022

Spatial cluster analysis reveals how segmental outflow patterns change over time in living mice

Darryl R Overby; Tiffany Baptiste; Daniel Duffill; Ester Reina-Torres

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2647. doi:

Perspective February 2022

Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms

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Colleen M. McDowell; Krishnakumar Kizhatil; Michael H. Elliott; Darryl R. Overby; Joseph van Batenburg-Sherwood; J. Cameron Millar; Markus H. Kuehn; Gulab Zode; Ted S. Acott; Michael G. Anderson; Sanjoy K. Bhattacharya; Jacques A. Bertrand; Terete Borras; Diane E. Bovenkamp; Lin Cheng; John Danias; Michael Lucio De Ieso; Yiqin Du; Jennifer A. Faralli; Rudolf Fuchshofer; Preethi S. Ganapathy; Haiyan Gong; Samuel Herberg; Humberto Hernandez; Peter Humphries; Simon W. M. John; Paul L. Kaufman; Kate E. Keller; Mary J. Kelley; Ruth A. Kelly; David Krizaj; Ajay Kumar; Brian C. Leonard; Raquel L. Lieberman; Paloma Liton; Yutao Liu; Katy C. Liu; Navita N. Lopez; Weiming Mao; Timur Mavlyutov; Fiona McDonnell; Gillian J. McLellan; Philip Mzyk; Andrews Nartey; Louis R. Pasquale; Gaurang C. Patel; Padmanabhan P. Pattabiraman; Donna M. Peters; Vijaykrishna Raghunathan; Ponugoti Vasantha Rao; Naga Rayana; Urmimala Raychaudhuri; Ester Reina-Torres; Ruiyi Ren; Douglas Rhee; Uttio Roy Chowdhury; John R. Samples; E. Griffen Samples; Najam Sharif; Joel S. Schuman; Val C. Sheffield; Cooper H. Stevenson; Avinash Soundararajan; Preeti Subramanian; Chenna Kesavulu Sugali; Yang Sun; Carol B. Toris; Karen Y. Torrejon; Amir Vahabikashi; Janice A. Vranka; Ting Wang; Colin E. Willoughby; Chen Xin; Hongmin Yun; Hao F. Zhang; Michael P. Fautsch; Ernst R. Tamm; Abbot F. Clark; C. Ross Ethier; W. Daniel Stamer
TAGS: eye, mice, ocular hypertension, intraocular pressure, perfusion
Invest. Ophthalmol. Vis. Sci.. 2022; 63(2):12. doi: https://doi.org/10.1167/iovs.63.2.12

ARVO Annual Meeting Abstract June 2021

Elevated IOP stimulates NO-mediated IOP homeostasis in mice

Ester Reina Torres; Jason YH Chang; Joseph van Batenburg-Sherwood; Daniel W Stamer; Darryl R Overby

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2781. doi:

ARVO Annual Meeting Abstract June 2021

TRPV4-mediated oscillatory calcium signaling in TM cells requires internal stores

David Krizaj; Sarah N Redmon; Jackson M Baumann; Joseph M Sherwood; Darryl R Overby; Oleg Yarishkin

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2749. doi:

ARVO Annual Meeting Abstract June 2021

Automated machine learning detection of transcellular pores in Schlemm’s canal endothelial cells exposed to stretch

Justino Rodrigues; Anil Bharath; Darryl R Overby

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):483. doi:

ARVO Annual Meeting Abstract June 2021

Vasoregulator Effects on Outflow Resistance, Flow Patterns and Distal Vessels in the Conventional Outflow Pathway of Mouse and Human Eyes

Fiona S McDonnell; Todd Fleming; Megan Kuhn; Heather Schmitt; Kristin Perkumas; Joseph van Batenburg-Sherwood; Alex S Huang; Darryl R Overby; Daniel W Stamer

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):469. doi:

ARVO Annual Meeting Abstract June 2021

Calcium-Dependent Transcellular Pore Formation in Schlemm’s Canal Endothelial Cells

Jacques Bertrand; Daniel W Stamer; Darryl R Overby

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):484. doi:

Glaucoma August 2020

Aqueous Humor Outflow Requires Active Cellular Metabolism in Mice

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Ester Reina-Torres; Alexandra Boussommier-Calleja; Joseph M. Sherwood; Darryl R. Overby
TAGS: aqueous humor, body temperature, eye, metabolism, mice, temperature
Invest. Ophthalmol. Vis. Sci.. 2020; 61(10):45. doi: https://doi.org/10.1167/iovs.61.10.45

Glaucoma May 2020

Age and Menopause Effects on Ocular Compliance and Aqueous Outflow

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Andrew J. Feola; Joseph M. Sherwood; Machelle T. Pardue; Darryl R. Overby; C. Ross Ethier
TAGS: glaucoma, menopause
Invest. Ophthalmol. Vis. Sci.. 2020; 61(5):16. doi: https://doi.org/10.1167/iovs.61.5.16

Glaucoma March 2020

The β 4 -Subunit of the Large-Conductance Potassium Ion Channel K Ca 1.1 Regulates Outflow Facility in Mice

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Jacques A. Bertrand; Martin Schicht; W. Daniel Stamer; David Baker; Joseph M. Sherwood; Elke Lütjen-Drecoll; David L. Selwood; Darryl R. Overby
TAGS: mice, potassium channel, eye
Invest. Ophthalmol. Vis. Sci.. 2020; 61(3):41. doi: https://doi.org/10.1167/iovs.61.3.41

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Blockade of the BK- a / β 4 potassium ion channel reduces outflow facility in mice

Jacques Alexander Bertrand; Joseph M Sherwood; Martin Schicht; Elke Lütjen-Drecoll; David Selwood; William D Stamer; Darryl R Overby

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5214. doi:

ARVO Annual Meeting Abstract July 2019

Actomyosin contractility and the vimentin cytoskeleton influence giant vacuole life-cycle in Schlemm’s canal endothelial cells

Darryl R Overby; Alice Spenlehauer; Andrea Cairoli; Joseph M Sherwood; Amir Vahabikashi; W Daniel Stamer; Chiu Fan Lee

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5122. doi:

ARVO Annual Meeting Abstract July 2019

Aqueous humour outflow requires active cellular metabolism

Ester Reina Torres; Joseph M Sherwood; Darryl R Overby

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5155. doi:

ARVO Annual Meeting Abstract July 2019

Elevated IOP increases Shear Stress in Schlemm’s Canal

Fiona McDonnell; Kristin Marie Perkumas; Nicole E. Ashpole; Joan Kalnitsky; Joseph M Sherwood; Darryl R Overby; W Daniel Stamer

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3181. doi:

ARVO Annual Meeting Abstract July 2018

DISTAL OUTFLOW RESISTANCE CAN BE REGULATED PHARMACOLOGICALLY

Fiona McDonnell; W. Michael Dismuke; Darryl R Overby; W Daniel Stamer

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6039. doi:

ARVO Annual Meeting Abstract July 2018

Impact of Estrogen Deficiency on Outflow Facility and Ocular Biomechanics in Rats

Andrew Feola; Joseph Sherwood; Darryl R Overby; Machelle T Pardue; C Ross Ethier

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1217. doi:

ARVO Annual Meeting Abstract July 2018

The effect of Ultrasound cycloplasty (UCP) using High Intensity Focused Ultrasound (HiFU) on aqueous humor dynamics

Pouya Alaghband; Elizabeth Angela P Galvis; Michael Madekurozwa; Esmail Eslah; Brian Chu; Darryl R Overby; K Sheng Lim

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1648. doi:

ARVO Annual Meeting Abstract July 2018

Modulation of outflow facility by the ocular pulse

Darryl R Overby; Michael Madekurozwa; W Daniel Stamer; Joseph Sherwood

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3971. doi:

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The effect of L-NAME on outflow facility in whole porcine eyes.

The relationship between pressure-dependent changes in outflow facility and dimensional changes in the anterior segment during perfusion of enucleated mouse eyes

Spatial cluster analysis reveals how segmental outflow patterns change over time in living mice

Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms

Elevated IOP stimulates NO-mediated IOP homeostasis in mice

TRPV4-mediated oscillatory calcium signaling in TM cells requires internal stores

Automated machine learning detection of transcellular pores in Schlemm’s canal endothelial cells exposed to stretch

Vasoregulator Effects on Outflow Resistance, Flow Patterns and Distal Vessels in the Conventional Outflow Pathway of Mouse and Human Eyes

Calcium-Dependent Transcellular Pore Formation in Schlemm’s Canal Endothelial Cells

Aqueous Humor Outflow Requires Active Cellular Metabolism in Mice

Age and Menopause Effects on Ocular Compliance and Aqueous Outflow

The β 4 -Subunit of the Large-Conductance Potassium Ion Channel K Ca 1.1 Regulates Outflow Facility in Mice

Blockade of the BK- a / β 4 potassium ion channel reduces outflow facility in mice

Actomyosin contractility and the vimentin cytoskeleton influence giant vacuole life-cycle in Schlemm’s canal endothelial cells

Aqueous humour outflow requires active cellular metabolism

Elevated IOP increases Shear Stress in Schlemm’s Canal

DISTAL OUTFLOW RESISTANCE CAN BE REGULATED PHARMACOLOGICALLY

Impact of Estrogen Deficiency on Outflow Facility and Ocular Biomechanics in Rats

The effect of Ultrasound cycloplasty (UCP) using High Intensity Focused Ultrasound (HiFU) on aqueous humor dynamics

Modulation of outflow facility by the ocular pulse

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