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Glaucoma July 2025

Polygenic Risk Prediction for Normal-Tension Glaucoma

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Maryam Marzban; Santiago Diaz Torres; Regina Yu; Weixiong He; David A. Mackey; Ayellet V. Segrè; Janey Wiggs; Stuart MacGregor; Puya Gharahkhani; on behalf of the International Glaucoma Genetics Consortium
TAGS: datasets, low tension glaucoma, polygenic risk score, genome-wide association study
Invest. Ophthalmol. Vis. Sci.. 2025; 66(9):4. https://doi.org/10.1167/iovs.66.9.4

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2025

Global Axial Length Growth Charts: A Comprehensive Study Across Continents in the CREAM-KIDS Consortium

Sander Kneepkens; Gareth Lingham; Dirk Jan van Hemert; Jan Roelof Polling; Willem Tideman; James Loughman; Niall C Strang; Weizhong Lan; Jeremy Guggenheim; Kathryn Saunders; Seang-Mei Saw; Siofra Christine Harrington; Laura Guisasola; Amanda French; Rigmor C Baraas; David A Mackey; Jason Yam; Olavi Pärssinen; Caroline C W Klaver; Ian Flitcroft

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):517.

ARVO Annual Meeting Abstract June 2025

Increased axial length in people with recent birth years parallels an increase in myopia

David A Mackey; Andrew Turpin; Bill Morgan; Timothy Lewis-Carroll; Samantha Sze-Yee Lee; Paul Sanfilippo; Gareth Lingham

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5223.

ARVO Annual Meeting Abstract June 2025

Monitoring of population refractive error distributions: is cycloplegia essential?

Gareth Lingham; David A Mackey; Amanda French; Gui-Shuang Ying; Hongguang Cui; Siofra Christine Harrington; James Loughman; Ian Flitcroft

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5222.

ARVO Annual Meeting Abstract June 2025

Optic disc measures and intraocular pressure after long-term continuous positive airway pressure treatment for sleep apnoea

Samantha Sze-Yee Lee; Nigel McArdle; Gareth Lingham; Bhajan Singh; David A Mackey

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1682.

Glaucoma April 2025

Longitudinal Change in Retinal Nerve Fiber Layer Thickness and Intraocular Pressure in Young Adults

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Samantha Sze-Yee Lee; Gareth Lingham; Alex W. Hewitt; David A. Mackey
TAGS: intraocular pressure, retinal nerve fiber layer, young adult, eye, ophthalmic examination and evaluation
Trans. Vis. Sci. Tech.. 2025; 14(4):3. https://doi.org/10.1167/tvst.14.4.3

Includes: Supplemental Content

Clinical and Epidemiologic Research August 2024

Choroidal Changes During and After Discontinuing Long-Term 0.01% Atropine Treatment for Myopia Control

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Samantha Sze-Yee Lee; Gareth Lingham; Antony Clark; Scott A. Read; David Alonso-Caneiro; David A. Mackey
TAGS: atropine, choroid, myopia, placebos, eyedrops
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):21. https://doi.org/10.1167/iovs.65.10.21

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

A metabolome-wide analysis of Intraocular pressure suggests neuroinflammatory mechanisms as possible mechanisms involved in glaucoma

Pirro G Hysi; Ajda Pristavec; Anthony P Khawaja; Jospeh Bastasic; David A Mackey; Janey L Wiggs; Jamie E Craig; Louis R Pasquale; Christopher J Hammond; Marie-Hélène Roy-Gagnon

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):997.

ARVO Annual Meeting Abstract June 2024

Effect of age at menarche and pregnancy on refractive error in young adult women

David A Mackey; Nicholas Ong; Samantha Sze-Yee Lee

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1195.

ARVO Annual Meeting Abstract June 2024

Polygenic prediction of keratoconus and its measures: cross-sectional and longitudinal analyses in community-based young adults

Samantha Sze-Yee Lee; Santiago Diaz Torres; Weixiong He; Elsie Chan; Elaine Chong; Puya Gharahkhani; Stuart MacGregor; Gareth Lingham; David A Mackey

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2852.

Glaucoma June 2024

Assessing the Efficacy of Synthetic Optic Disc Images for Detecting Glaucomatous Optic Neuropathy Using Deep Learning

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Abadh K. Chaurasia; Stuart MacGregor; Jamie E. Craig; David A. Mackey; Alex W. Hewitt
TAGS: datasets, glaucoma, optic disk, optic nerve disorders, deep learning, training
Trans. Vis. Sci. Tech.. 2024; 13(6):1. https://doi.org/10.1167/tvst.13.6.1

Includes: Supplemental Content

Clinical and Epidemiologic Research November 2023

Changes in Refractive Error During Young Adulthood: The Effects of Longitudinal Screen Time, Ocular Sun Exposure, and Genetic Predisposition

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Samantha Sze-Yee Lee; Gareth Lingham; Carol A. Wang; Santiago Diaz Torres; Craig E. Pennell; Pirro G. Hysi; Christopher J. Hammond; Puya Gharahkhani; Rosie Clark; Jeremy A. Guggenheim; David A. Mackey
TAGS: adult, genetic predisposition to disease, myopia, refractive errors, screen time, sun exposure
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):28. https://doi.org/10.1167/iovs.64.14.28

Includes: Supplemental Content

Refractive Intervention August 2023

Distribution of Axial Length in Australians of Different Age Groups, Ethnicities, and Refractive Errors

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Vinay Kumar Nilagiri; Samantha Sze-Yee Lee; Gareth Lingham; Jason Charng; Seyhan Yazar; Alex W. Hewitt; Lyn R. Griffiths; Paul G. Sanfilippo; Tzu-Hsun Tsai; David A. Mackey
TAGS: ethnic group, refractive errors, myopia, eye
Trans. Vis. Sci. Tech.. 2023; 12(8):14. https://doi.org/10.1167/tvst.12.8.14

Includes: Supplemental Content

Glaucoma February 2023

Genetic Associations Between Smoking- and Glaucoma-Related Traits

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Jessica H. Tran; Kelsey V. Stuart; Victor de Vries; Joëlle E. Vergroesen; Clara C. Cousins; Pirro G. Hysi; Ron Do; Ghislain Rocheleau; Jae H. Kang; Janey L. Wiggs; Stuart MacGregor; Anthony P. Khawaja; David A. Mackey; Caroline C. W. Klaver; Wishal D. Ramdas; Louis R. Pasquale; for the UK Biobank Eye and Vision Consortium, and for the International Glaucoma Genetics Consortium
TAGS: genetics, glaucoma, smoking
Trans. Vis. Sci. Tech.. 2023; 12(2):20. https://doi.org/10.1167/tvst.12.2.20

Includes: Supplemental Content

Retina January 2023

Microperimetry and Adaptive Optics Imaging Reveal Localized Functional and Structural Changes in Asymptomatic RPGR Mutation Carriers

PDF

Danial Roshandel; Tina M. Lamey; Jason Charng; Rachael C. Heath Jeffery; Terri L. McLaren; Jennifer A. Thompson; John N. De Roach; Samuel McLenachan; David A. Mackey; Fred K. Chen
TAGS: diagnostic imaging, mutation, optics
Invest. Ophthalmol. Vis. Sci.. 2023; 64(1):3. https://doi.org/10.1167/iovs.64.1.3

Includes: Supplemental Content

Glaucoma October 2022

Attitudes Toward Glaucoma Genetic Risk Assessment in Unaffected Individuals

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Georgina L. Hollitt; Owen M. Siggs; Bronwyn Ridge; Miriam C. Keane; David A. Mackey; Stuart MacGregor; Alex W. Hewitt; Jamie E. Craig; Emmanuelle Souzeau
TAGS: genetic risk, glaucoma, attitude
Trans. Vis. Sci. Tech.. 2022; 11(10):38. https://doi.org/10.1167/tvst.11.10.38

Includes: Supplemental Content

Retina July 2022

The Relationship Between Fetal Growth and Retinal Nerve Fiber Layer Thickness in a Cohort of Young Adults

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Kathleen I. C. Dyer; Paul G. Sanfilippo; Seyhan Yazar; Jamie E. Craig; Alex W. Hewitt; John P. Newnham; David A. Mackey; Samantha S. Y. Lee
TAGS: cohort studies, fetal growth, retinal nerve fiber layer, young adult, pregnancy, birth weight, fetus
Trans. Vis. Sci. Tech.. 2022; 11(7):8. https://doi.org/10.1167/tvst.11.7.8

Includes: Supplemental Content

Genetics June 2022

Sonic Hedgehog Intron Variant Associated With an Unusual Pediatric Cortical Cataract

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Terri L. Young; Kristina N. Whisenhunt; Sarah M. LaMartina; Alex W. Hewitt; David A. Mackey; Stuart W. Tompson
TAGS: cataract, childhood, cortical cataract, introns, pediatrics, shh gene, enhancer of transcription, genes, genetic pedigree
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):25. https://doi.org/10.1167/iovs.63.6.25

Retina June 2022

Axial Length Distributions in Patients With Genetically Confirmed Inherited Retinal Diseases

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Katie M. Williams; Michalis Georgiou; Angelos Kalitzeos; Isabelle Chow; Pirro G. Hysi; Anthony G. Robson; Gareth Lingham; Fred K. Chen; David A. Mackey; Andrew R. Webster; Christopher J. Hammond; Polina Prokhoda; Joseph Carroll; Michel Michaelides; Omar A. Mahroo
TAGS: advanced life support, amyotrophic lateral sclerosis, antilymphocyte globulin, cohort studies, oculocutaneous albinism type 2, retinal diseases, albinism, abca4 gene, eye
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):15. https://doi.org/10.1167/iovs.63.6.15

ARVO Annual Meeting Abstract June 2022

Change in peripapillary retinal nerve fibre layer thickness from 20 to 28 years old

Samantha Sze-Yee Lee; Alex W Hewitt; David A Mackey

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1629 – A0124.

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Polygenic Risk Prediction for Normal-Tension Glaucoma

Global Axial Length Growth Charts: A Comprehensive Study Across Continents in the CREAM-KIDS Consortium

Increased axial length in people with recent birth years parallels an increase in myopia

Monitoring of population refractive error distributions: is cycloplegia essential?

Optic disc measures and intraocular pressure after long-term continuous positive airway pressure treatment for sleep apnoea

Longitudinal Change in Retinal Nerve Fiber Layer Thickness and Intraocular Pressure in Young Adults

Choroidal Changes During and After Discontinuing Long-Term 0.01% Atropine Treatment for Myopia Control

A metabolome-wide analysis of Intraocular pressure suggests neuroinflammatory mechanisms as possible mechanisms involved in glaucoma

Effect of age at menarche and pregnancy on refractive error in young adult women

Polygenic prediction of keratoconus and its measures: cross-sectional and longitudinal analyses in community-based young adults

Assessing the Efficacy of Synthetic Optic Disc Images for Detecting Glaucomatous Optic Neuropathy Using Deep Learning

Changes in Refractive Error During Young Adulthood: The Effects of Longitudinal Screen Time, Ocular Sun Exposure, and Genetic Predisposition

Distribution of Axial Length in Australians of Different Age Groups, Ethnicities, and Refractive Errors

Genetic Associations Between Smoking- and Glaucoma-Related Traits

Microperimetry and Adaptive Optics Imaging Reveal Localized Functional and Structural Changes in Asymptomatic RPGR Mutation Carriers

Attitudes Toward Glaucoma Genetic Risk Assessment in Unaffected Individuals

The Relationship Between Fetal Growth and Retinal Nerve Fiber Layer Thickness in a Cohort of Young Adults

Sonic Hedgehog Intron Variant Associated With an Unusual Pediatric Cortical Cataract

Axial Length Distributions in Patients With Genetically Confirmed Inherited Retinal Diseases

Change in peripapillary retinal nerve fibre layer thickness from 20 to 28 years old

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