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ARVO Annual Meeting Abstract June 2022

Early photoreceptor trajectories towards a cancer-predisposed cone precursor state

Dominic Shayler; Kevin Stachelek; Sunhye Lee; Yeha Kim; Mitali Singh; Maxwell Bay; Matthew Thornton; Narine Harutyunyan; Andrew Salas; Kayla Stepanian; Jennifer Aparicio; Brendan Grubbs; Michael Bonaguidi; Hardeep Singh; David Cobrinik

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4282. doi:

ARVO Annual Meeting Abstract June 2021

Establishing Clinical Utility of ctDNA Analysis for Diagnosis, Prognosis, and Treatment Monitoring of Retinoblastoma: the Aqueous Humor Liquid Biopsy

Liya Xu; Mary E Kim; Ashley Polski; Rishvanth K. Prabakar; Lishuang Shen; Chen-Ching Peng; Mark Reid; Patricia Chevez-Barrios; Jonathan Kim; Peter Kuhn; David Cobrinik; James Hicks; Jesse L Berry

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2839. doi:

Articles September 2020

Cell-Free DNA Tumor Fraction in the Aqueous Humor Is Associated With Therapeutic Response in Retinoblastoma Patients

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Ashley Polski; Liya Xu; Rishvanth K. Prabakar; Jonathan W. Kim; Rachana Shah; Rima Jubran; Peter Kuhn; David Cobrinik; James Hicks; Jesse L. Berry
TAGS: aqueous humor, cell-free dna, neoplasms, retinoblastoma, hypertension
Trans. Vis. Sci. Tech.. 2020; 9(10):30. doi: https://doi.org/10.1167/tvst.9.10.30

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Gain of chromosome 6p is a molecular biomarker for prognostication of retinoblastoma ocular survival: The aqueous humor surrogate tumor biopsy

Jesse L Berry; Liya Xu; Ashley Polski; Rishvanth Prabakar; mark reid; jonathan kim; peter kuhn; David Cobrinik; Jim Hicks

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2805. doi:

ARVO Annual Meeting Abstract June 2020

Longitudinal aqueous humor sampling reflects treatment response in retinoblastoma patients

Ashley Polski; Liya Xu; Rishvanth Prabakar; Jonathan W. Kim; peter kuhn; David Cobrinik; Jim Hicks; Jesse L Berry

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1394. doi:

ARVO Annual Meeting Abstract June 2020

Characterization and staging of outer plexiform layer morphogenesis and synaptogenesis in human retinal organoids

Sumitha Prameela Bharathan; Angela Ferrario; Kayla Stepanian; Rosanna Calderon; G. Esteban Fernandez; mark reid; Carolyn Marks; Matthew Thornton; Brendan Grubbs; Thomas Lee; David Cobrinik; Jennifer Aparicio; Aaron Nagiel

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4015. doi:

ARVO Annual Meeting Abstract July 2019

MYCN Overexpression Induces Cone Precursor Proliferation and Tumorigenesis in Explanted Retinae

Hardeep Pal Singh; Matthew Thornton; Brendan Grubbs; David Cobrinik

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1320. doi:

ARVO Annual Meeting Abstract July 2019

Normal retinal ganglion cell (RGC) production and candidate disease associated genes identified in optic nerve hypoplasia (ONH)

Jennifer Aparicio; Hannah Hopp; Laura Li; Kevin Stachelek; Narine Harutyunyan; David Craig; David Cobrinik; Mark Borchert

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3595. doi:

ARVO Annual Meeting Abstract July 2019

NCL is implicated in the NXNL1 gene splicing and leads to RdCVF expression in retinoblastoma cell lines

Najate Ait-Ali; Frédéric Blond; Sunhye Lee; Sijia Wang; David Cobrinik; Thierry D Leveillard

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4940. doi:

ARVO Annual Meeting Abstract July 2018

pRB Loss Induces Human Cone Precursor Proliferation and Inward Migration in Intact Cultured Retina

Hardeep Pal Singh; David Koos; Esteban Fernandez; Matthew E Thornton; Brendan H Grubbs; Rex Moats; Scott Fraser; David Cobrinik

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4961. doi:

ARVO Annual Meeting Abstract July 2018

Chromosomal Analysis in the Aqueous Humor of Retinoblastoma eyes is predictive of globe salvage: the Surrogate Tumor Biopsy

Jesse L Berry; Irsan Kooi; Liya Xu; A Linn Murphree; Bao Han Allison Le; Subramanian Krishnan; Kevin Stachelek; Thomas C Lee; Jonathan W Kim; Peter Kuhn; David Cobrinik; James Hicks

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1637. doi:

Retinal Cell Biology July 2017

Structural and Functional Characterization of Human Stem-Cell-Derived Retinal Organoids by Live Imaging

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Andrew W. Browne; Cosimo Arnesano; Narine Harutyunyan; Thien Khuu; Juan Carlos Martinez; Harvey A. Pollack; David S. Koos; Thomas C. Lee; Scott E. Fraser; Rex A. Moats; Jennifer G. Aparicio; David Cobrinik
TAGS: diagnostic imaging, organoids
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3311-3318. doi: https://doi.org/10.1167/iovs.16-20796

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Aqueous Humor as a Surrogate Liquid Tumor Biopsy in Retinoblastoma

Jesse L Berry; Liya Xu; Kevin Stachelek; A. Linn Murphree; Emily Zolfoghari; Kathleen McGovern; Thomas Lee; Anders Carlsson; Peter Kuhn; Jonathan Kim; David Cobrinik; James Hicks

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):856. doi:

ARVO Annual Meeting Abstract September 2016

Human Stem Cell Derived Retinal Spheroids Characterized Non-Invasively for Structure and Function by Multimodal Imaging

Andrew Browne; Cosimo Arnesano; Thien Kuu; Harvey Pollack; Rex Moats; Lee Thomas; Jennifer Aparicio; Scott Fraser; David Cobrinik

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

Human Cone Precursor Program Underlying a Proliferative Response to pRB Loss

Hardeep Pal Singh; Sijia Wang; David Cobrinik

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):556. doi:

ARVO Annual Meeting Abstract June 2015

Altered RB and p27 expression patterns in hESC-derived versus fetal retinal cone-precursors

Dominic Shayler; Hardeep Pal Singh; Narine Harutyunyan; David Cobrinik

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3587. doi:

ARVO Annual Meeting Abstract June 2015

A Human Cone Precursor Program Underlying a Proliferative Response to RB Loss

Hardeep Pal Singh; David Cobrinik; Retinal development and cell biology

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):442. doi:

ARVO Annual Meeting Abstract June 2015

MDM2 Targeting sd-rxRNA® for Retinoblastoma Therapy

Kevin Stachelek; James Cardia; Donglai Qi; Hardeep Pal Singh; Lakshmipathi Pandarinathan; Katherine Holton; Karen Bulock; Pamela A Pavco; David Cobrinik; Michael Byrne

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5473. doi:

ARVO Annual Meeting Abstract April 2014

Evaluation of Human Embryonic Stem Cell-Derived Retina as a Potential Retinoblastoma Model

Victor Liao; Narine Harutyunyan; Jennifer Aparicio; David Cobrinik; Thomas C Lee

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2984. doi:

ARVO Annual Meeting Abstract April 2014

An Update on the Development of sd-rxRNA for Retinoblastoma Therapy

Michael Byrne; Donglai Qi; Kevin Stachelek; Hardeep Singh; James Cardia; Lakshmipathi Panderarinathan; Katherine Holton; Karen Bulock; David Cobrinik; Pamela A Pavco

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):6020. doi:

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Early photoreceptor trajectories towards a cancer-predisposed cone precursor state

Establishing Clinical Utility of ctDNA Analysis for Diagnosis, Prognosis, and Treatment Monitoring of Retinoblastoma: the Aqueous Humor Liquid Biopsy

Cell-Free DNA Tumor Fraction in the Aqueous Humor Is Associated With Therapeutic Response in Retinoblastoma Patients

Gain of chromosome 6p is a molecular biomarker for prognostication of retinoblastoma ocular survival: The aqueous humor surrogate tumor biopsy

Longitudinal aqueous humor sampling reflects treatment response in retinoblastoma patients

Characterization and staging of outer plexiform layer morphogenesis and synaptogenesis in human retinal organoids

MYCN Overexpression Induces Cone Precursor Proliferation and Tumorigenesis in Explanted Retinae

Normal retinal ganglion cell (RGC) production and candidate disease associated genes identified in optic nerve hypoplasia (ONH)

NCL is implicated in the NXNL1 gene splicing and leads to RdCVF expression in retinoblastoma cell lines

pRB Loss Induces Human Cone Precursor Proliferation and Inward Migration in Intact Cultured Retina

Chromosomal Analysis in the Aqueous Humor of Retinoblastoma eyes is predictive of globe salvage: the Surrogate Tumor Biopsy

Structural and Functional Characterization of Human Stem-Cell-Derived Retinal Organoids by Live Imaging

Aqueous Humor as a Surrogate Liquid Tumor Biopsy in Retinoblastoma

Human Stem Cell Derived Retinal Spheroids Characterized Non-Invasively for Structure and Function by Multimodal Imaging

Human Cone Precursor Program Underlying a Proliferative Response to pRB Loss

Altered RB and p27 expression patterns in hESC-derived versus fetal retinal cone-precursors

A Human Cone Precursor Program Underlying a Proliferative Response to RB Loss

MDM2 Targeting sd-rxRNA® for Retinoblastoma Therapy

Evaluation of Human Embryonic Stem Cell-Derived Retina as a Potential Retinoblastoma Model

An Update on the Development of sd-rxRNA for Retinoblastoma Therapy

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