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ARVO Annual Meeting Abstract June 2024

OTII OVA-specific Tregs can be Induced to Traffic into the Mouse Eye and Modulate Experimental Autoimmune Uveoretinitis via Intravitreal Injection of Ovalbumin Peptide.

Alan Roy Abraham; Panayiotis Maghsoudlou; Suci Cendanawati; Alison J Clare; David Alexander Copland; Lindsay B Nicholson; Andrew D Dick

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2993.

ARVO Annual Meeting Abstract June 2023

Intravitreal AAV delivery causes long-term subclinical microglia activation in mice

Philip Michael Langer; Amy Ward; Oliver Hugh Bell; Alison J Clare; Colin Chu; Ying Kai Chan; Andrew Dick; David Copland

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):781.

ARVO Annual Meeting Abstract June 2023

IL-23 drives uveitis by acting on a novel population of resident ocular T cells

David Copland; Robert Hedley; Amy Ward; Colin Chu; Jonathan Sherlock; Andrew D Dick

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2864.

Articles October 2019

Modelling Macular Edema: The Effect of IL-6 and IL-6R Blockade on Human Blood–Retinal Barrier Integrity In Vitro

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Marina Mesquida; Faye Drawnel; Philippa J. Lait; David A. Copland; Madeleine L. Stimpson; Victor Llorenç; Maite Sainz de la Maza; Alfredo Adan; Gabriella Widmer; Pamela Strassburger; Sascha Fauser; Andrew D. Dick; Richard W. J. Lee; Blanca Molins
TAGS: interleukin 6 receptor, interleukin-6, macular edema, personal integrity, blood-retinal barrier
Trans. Vis. Sci. Tech.. 2019; 8(5):32. https://doi.org/10.1167/tvst.8.5.32

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Interleukin-33 attenuates ocular angiogenesis through a mast cell dependent pathway.

Sofia Theodoropoulou; David Copland; Kepeng Ou; Jian Liu; Neal Millar; Andrew D Dick

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):987.

ARVO Annual Meeting Abstract July 2019

Mapping interleukin-33 to metabolic function in the retinal pigment epithelium

Louis Scott; Emma E Vincent; Natalie Hudson; David Copland; Kate Heesom; Matthew Campbell; Andrew Halestrap; Andrew D Dick; Sofia Theodoropoulou

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1685.

ARVO Annual Meeting Abstract July 2019

RNA-Seq Reveals Alterations in Homeostatic Microglial Function during Inflammation and Resolution

Oliver Hugh Bell; David Copland; Amy Ward; Colin J Chu; Clemens Lange; Andrew D Dick

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2800.

ARVO Annual Meeting Abstract July 2019

Gene therapy for Glaucoma by CRISPR-Cas9 mediated disruption of Aquaporin 1 in the Ciliary Body

Colin J Chu; Jiahui Wu; Oliver Hugh Bell; David Copland; Ryea Maswood; Alison Young; John Pooley; Peng Tee Khaw; Robin R Ali; Andrew D Dick

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5120.

ARVO Annual Meeting Abstract July 2019

Upregulation of CX3CR1 on CD4+ T cells during Experimental Autoimmune Uveoretinitis

Amy Ward; Oliver Hugh Bell; Louis Scott; David Copland; Andrew D Dick; Lindsay B Nicholson

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):784.

Special Issue July 2018

A Perspective of AMD Through the Eyes of Immunology

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David A. Copland; Sofia Theodoropoulou; Jian Liu; Andrew D. Dick
TAGS: body tissue, eye, immunology, inflammation, complement system proteins, microglia
Invest. Ophthalmol. Vis. Sci.. 2018; 59(4):AMD83-AMD92. https://doi.org/10.1167/iovs.18-23893

ARVO Annual Meeting Abstract July 2018

Modulation of mast cells regulates retinal microenvironment and vascular integrity.

Sofia Theodoropoulou; David A Copland; Jian Liu; Louis Scott; Jiahui Wu; Andrew D Dick

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5555.

ARVO Annual Meeting Abstract June 2017

Interleukin 33 attenuates choroidal neovascularization by activating mast cells.

Sofia Theodoropoulou; David A Copland; Jian Liu; Jiahui Wu; Andrew D Dick

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1627.

ARVO Annual Meeting Abstract June 2017

In vitro effects of IL-6 and IL-6R blockade on the blood-retinal barrier

Marina Mesquida; David A Copland; Philippa J P Lait; Victor Llorens; Maite Sainz De La Maza; Alfredo Adan Civera; Andrew D Dick; Richard W J Lee; Blanca Molins

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5728.

ARVO Annual Meeting Abstract September 2016

In vitro effects of interleukin-6 on the outer blood-retinal barrier

Marina Mesquida; Philippa J P Lait; David Alexander Copland; Jian Liu; Victor Llorens; Maite Sainz De La Maza; Alfredo Adan Civera; Andrew D Dick; Richard W J Lee; Blanca Molins

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4184.

ARVO Annual Meeting Abstract June 2015

Interleukin 33/ST2 signaling regulates inflammatory response in choroidal stroma: implications for age-related macular degeneration.

Sofia Theodoropoulou; Jian Liu; Dong Li; Damo Xu; Iain McInnes; David A Copland; Andrew D Dick

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):841.

ARVO Annual Meeting Abstract June 2015

Novel anti-TNF-α antibody mimetic to treat ocular inflammation

David A Copland; Hanieh Khalili; Richard W J Lee; Peng Tee Khaw; Steve Brocchini; Andrew D Dick

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3210.

ARVO Annual Meeting Abstract June 2015

The role of impaired retinal pigment epithelial function in modulating macrophage activation

Jian Liu; David A Copland; Sofia Theodoropoulou; Miriam Barba; Lindsay B Nicholson; Andrew D Dick; Academic Unit of Ophthalmology, School of Clinical Sciences, University of Bristol, Bristol, United Kingdom

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3551.

ARVO Annual Meeting Abstract June 2015

The role of LRG1 in the regulation of angiogenesis in Experimental Autoimmune Uveoretinitis.

Gemma Beers; Natasha Jeffs; David A Copland; Peter S Adamson; Virginia L Calder; Lindsay B Nicholson; Stephen E Moss; John Greenwood; Andrew D Dick

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2313.

ARVO Annual Meeting Abstract April 2014

Characterising the role of lipoprotein-associated phospholipase A 2 (Lp-PLA 2 ) in experimental autoimmune uveoretinitis (EAU)

Gemma Beers; Joanne Boldison; David Alexander Copland; Peter S Adamson; Lindsay B Nicholson; Andrew D Dick

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2500.

ARVO Annual Meeting Abstract April 2014

Impaired autophagy in retinal pigment epithelial cells induces inflammatory responses in macrophages

Jian Liu; David Alexander Copland; Hsi An Amy Chiu; Lindsay B Nicholson; Andrew D Dick

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):66.

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OTII OVA-specific Tregs can be Induced to Traffic into the Mouse Eye and Modulate Experimental Autoimmune Uveoretinitis via Intravitreal Injection of Ovalbumin Peptide.

Intravitreal AAV delivery causes long-term subclinical microglia activation in mice

IL-23 drives uveitis by acting on a novel population of resident ocular T cells

Modelling Macular Edema: The Effect of IL-6 and IL-6R Blockade on Human Blood–Retinal Barrier Integrity In Vitro

Interleukin-33 attenuates ocular angiogenesis through a mast cell dependent pathway.

Mapping interleukin-33 to metabolic function in the retinal pigment epithelium

RNA-Seq Reveals Alterations in Homeostatic Microglial Function during Inflammation and Resolution

Gene therapy for Glaucoma by CRISPR-Cas9 mediated disruption of Aquaporin 1 in the Ciliary Body

Upregulation of CX3CR1 on CD4+ T cells during Experimental Autoimmune Uveoretinitis

A Perspective of AMD Through the Eyes of Immunology

Modulation of mast cells regulates retinal microenvironment and vascular integrity.

Interleukin 33 attenuates choroidal neovascularization by activating mast cells.

In vitro effects of IL-6 and IL-6R blockade on the blood-retinal barrier

In vitro effects of interleukin-6 on the outer blood-retinal barrier

Interleukin 33/ST2 signaling regulates inflammatory response in choroidal stroma: implications for age-related macular degeneration.

Novel anti-TNF-α antibody mimetic to treat ocular inflammation

The role of impaired retinal pigment epithelial function in modulating macrophage activation

The role of LRG1 in the regulation of angiogenesis in Experimental Autoimmune Uveoretinitis.

Characterising the role of lipoprotein-associated phospholipase A 2 (Lp-PLA 2 ) in experimental autoimmune uveoretinitis (EAU)

Impaired autophagy in retinal pigment epithelial cells induces inflammatory responses in macrophages

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