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ARVO Annual Meeting Abstract June 2024

Live-cell imaging of dynamic cellular events in RPE cells

David S Williams

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):13.

ARVO Annual Meeting Abstract June 2021

SARS-CoV2 Infection damages RPE Function and Suvival

Nan Hultgren; Barry Burgess; David S Williams

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2984.

ARVO Annual Meeting Abstract June 2021

Spatiotemporal dynamics of photoreceptor outer segment phagosome ingestion by the retinal pigment epithelium

Ankita Umapathy; Julie Chung; Madeline Tomlinson; Caleb Lim; David S Williams

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2952.

ARVO Annual Meeting Abstract June 2021

3D Ultrastructural Deconstruction of Rod Synapses after Retinal Detachment.

Gil Torten; Kenneth A. Linberg; Gabriel Luna; Guy A. Perkins; Mark H. Ellisman; David S. Williams; Steven K. Fisher

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3096.

ARVO Annual Meeting Abstract June 2020

Multimodal imaging in patients with MYO7A- related Usher syndrome

Leslie Small; Jessica Wong; Mark E Pennesi; Hao Zhou; Ruikang K Wang; Abhishek Chadha; David S Williams; Austin Roorda; Travis Proco; Jacque L Duncan

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):228.

ARVO Annual Meeting Abstract July 2019

Peripherin-2/rds functions for photoreceptor disk morphology by bending membranes

Andrew F X Goldberg; Michelle Lynn Milstein; Breyanna Lynn Cavanaugh; Stefanie Volland; David S Williams

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):573.

ARVO Annual Meeting Abstract July 2018

A Rapid protocol for the differentiation of human ARPE-19 cells

Roni A Hazim; Stefanie Volland; David S Williams

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3980.

ARVO Annual Meeting Abstract June 2017

RPE autonomous molecular events are sufficient for drusen biogenesis and extracellular matrix alterations in hiPSC-derived models of macular degeneration.

Ruchira Singh; Sonal Dalvi; Leslie MacDonald; Sandy Hung; Alex W Hewitt; Alice Pebay; David S Williams; Chad Alan Galloway

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3761.

ARVO Annual Meeting Abstract September 2016

Routing of opsin to the cilium

Abhishek Chadha; Stefanie Volland; David S Williams

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):568.

ARVO Annual Meeting Abstract September 2016

Mutations in CFH perturb RPE homeostasis in vitro

Roni Hazim; David S Williams

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6046.

ARVO Annual Meeting Abstract April 2014

A Three-Dimensional Culture Method to Expand Limbal Stem/Progenitor Cells

Hua Mei; Sheyla Gonzalez; Martin N Nakatsu; Elfren Ray Baclagon; Vanda S Lopes; David S Williams; Sophie Xiaohui Deng

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):527.

ARVO Annual Meeting Abstract April 2014

The Mouse Homolog of the Human LCA3 Gene, Spata7, Plays a Critical Role in Cilium Structural Maintenance and Protein Trafficking in Photoreceptor Cells

Rui Chen; Aiden Eblimit; Yiyun Chen; Minh Nguyen; Julian Esteve-Rudd; Lin Gan; Samuel M Wu; David S Williams; Ronald Roepman; Graeme Mardon

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):6315.

ARVO Annual Meeting Abstract March 2012

AMD-like Pathology in Klc1-/- Mice

Julian Esteve-Rudd; Concepcion Lillo; David S. Williams

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):4756.

Retina October 2011

Retinal Disease Course in Usher Syndrome 1B Due to MYO7A Mutations

PDF

Samuel G. Jacobson; Artur V. Cideciyan; Dan Gibbs; Alexander Sumaroka; Alejandro J. Roman; Tomas S. Aleman; Sharon B. Schwartz; Melani B. Olivares; Robert C. Russell; Janet D. Steinberg; Margaret A. Kenna; William J. Kimberling; Heidi L. Rehm; David S. Williams
TAGS: kinetics, mutation, perimetry, retina, retinal cone, retinal diseases, rod photoreceptors, usher syndrome, vision, photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2011; 52(11):7924-7936. https://doi.org/10.1167/iovs.11-8313

Includes: Supplemental Content

Retinal Cell Biology February 2010

Function of MYO7A in the Human RPE and the Validity of Shaker1 Mice as a Model for Usher Syndrome 1B

PDF

Daniel Gibbs; Tanja Diemer; Kornnika Khanobdee; Jane Hu; Dean Bok; David S. Williams
TAGS: cell motility, melanosomes, mice, retinal pigment cell, usher syndrome, validity of results, fetus
Invest. Ophthalmol. Vis. Sci.. 2010; 51(2):1130-1135. https://doi.org/10.1167/iovs.09-4032

Includes: Multimedia, Supplemental Content

Retina September 2009

Retinal Pigment Epithelium Defects in Humans and Mice with Mutations in MYO7A : Imaging Melanosome-Specific Autofluorescence

PDF

Daniel Gibbs; Artur V. Cideciyan; Samuel G. Jacobson; David S. Williams
TAGS: autofluorescence, diagnostic imaging, melanosomes, mice, mutation, retinal pigment epithelium
Invest. Ophthalmol. Vis. Sci.. 2009; 50(9):4386-4393. https://doi.org/10.1167/iovs.09-3471

Includes: Supplemental Content

Retina August 2009

Harmonin in the Murine Retina and the Retinal Phenotypes of Ush1c -Mutant Mice and Human USH1C

PDF

David S. Williams; Tomas S. Aleman; Concepción Lillo; Vanda S. Lopes; Louise C. Hughes; Edwin M. Stone; Samuel G. Jacobson
TAGS: mice, phenotype, retina, antibodies, photoreceptors, synapses, protein isoforms, proteins
Invest. Ophthalmol. Vis. Sci.. 2009; 50(8):3881-3889. https://doi.org/10.1167/iovs.08-3358

Includes: Supplemental Content

Retina March 2008

Nrl -Knockout Mice Deficient in Rpe65 Fail to Synthesize 11- cis Retinal and Cone Outer Segments

PDF

Kecia L. Feathers; Arkady L. Lyubarsky; Naheed W. Khan; Karen Teofilo; Anand Swaroop; David S. Williams; Edward N. Pugh, Jr; Debra A. Thompson
TAGS: mice, retinal cone, retinoids, eye
Invest. Ophthalmol. Vis. Sci.. 2008; 49(3):1126-1135. https://doi.org/10.1167/iovs.07-1234

Retinal Cell Biology November 2006

Analysis of Kinesin-2 Function in Photoreceptor Cells Using Synchronous Cre -loxP Knockout of Kif3a with RHO-Cre

PDF

David Jimeno; Leonard Feiner; Concepcion Lillo; Karen Teofilo; Lawrence S. B. Goldstein; Eric A. Pierce; David S. Williams
TAGS: kinesin, mice, opsin, photoreceptors, retina, rod photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2006; 47(11):5039-5046. https://doi.org/10.1167/iovs.06-0032

Retina June 2005

Cone-like Morphological, Molecular, and Electrophysiological Features of the Photoreceptors of the Nrl Knockout Mouse

PDF

Lauren L. Daniele; Concepcion Lillo; Arkady L. Lyubarsky; Sergei S. Nikonov; Nancy Philp; Alan J. Mears; Anand Swaroop; David S. Williams; Edward N. Pugh, Jr
TAGS: photoreceptors, retinal cone, mice, retina
Invest. Ophthalmol. Vis. Sci.. 2005; 46(6):2156-2167. https://doi.org/10.1167/iovs.04-1427

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Live-cell imaging of dynamic cellular events in RPE cells

SARS-CoV2 Infection damages RPE Function and Suvival

Spatiotemporal dynamics of photoreceptor outer segment phagosome ingestion by the retinal pigment epithelium

3D Ultrastructural Deconstruction of Rod Synapses after Retinal Detachment.

Multimodal imaging in patients with MYO7A- related Usher syndrome

Peripherin-2/rds functions for photoreceptor disk morphology by bending membranes

A Rapid protocol for the differentiation of human ARPE-19 cells

RPE autonomous molecular events are sufficient for drusen biogenesis and extracellular matrix alterations in hiPSC-derived models of macular degeneration.

Routing of opsin to the cilium

Mutations in CFH perturb RPE homeostasis in vitro

A Three-Dimensional Culture Method to Expand Limbal Stem/Progenitor Cells

The Mouse Homolog of the Human LCA3 Gene, Spata7, Plays a Critical Role in Cilium Structural Maintenance and Protein Trafficking in Photoreceptor Cells

AMD-like Pathology in Klc1-/- Mice

Retinal Disease Course in Usher Syndrome 1B Due to MYO7A Mutations

Function of MYO7A in the Human RPE and the Validity of Shaker1 Mice as a Model for Usher Syndrome 1B

Retinal Pigment Epithelium Defects in Humans and Mice with Mutations in MYO7A : Imaging Melanosome-Specific Autofluorescence

Harmonin in the Murine Retina and the Retinal Phenotypes of Ush1c -Mutant Mice and Human USH1C

Nrl -Knockout Mice Deficient in Rpe65 Fail to Synthesize 11- cis Retinal and Cone Outer Segments

Analysis of Kinesin-2 Function in Photoreceptor Cells Using Synchronous Cre -loxP Knockout of Kif3a with RHO-Cre

Cone-like Morphological, Molecular, and Electrophysiological Features of the Photoreceptors of the Nrl Knockout Mouse

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